2bih - Revision history

OCA at 13:39, 13 December 2023

2023-12-13T13:39:02Z

←Older revision		Revision as of 13:39, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2bih' size='340' side='right'caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2bih' size='340' side='right'caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MTV:(MOLYBDOPTERIN~~-S,~~S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2bii\|2bii]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Nitrate_reductase_~~(~~NAD(P~~)~~H) Nitrate reductase~~ (~~NAD(P~~)~~H)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [https://pdbe.org/2bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [https://www.ebi.ac.uk/pdbsum/2bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bih ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [https://pdbe.org/2bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [https://www.ebi.ac.uk/pdbsum/2bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NIA_PICAN NIA_PICAN]] Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	+	[https://www.uniprot.org/uniprot/NIA_PICAN NIA_PICAN] Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Barbier, G]]	+	[[Category: Ogataea angusta]]
-	[[Category: Campbell~~, W H~~]]	+	[[Category: Barbier G]]
-	[[Category: Fischer, K]]	+	[[Category: Campbell WH]]
-	[[Category: Hecht, H J]]	+	[[Category: Fischer K]]
-	[[Category: Mendel~~, R R~~]]	+	[[Category: Hecht H-J]]
-	[[Category: Schwarz, G]]	+	[[Category: Mendel RR]]
-	~~[[Category: Flavoprotein]]~~	+	[[Category: Schwarz G]]
-	~~[[Category: Nitrate assimilation]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 13:10, 24 November 2021

2021-11-24T13:10:34Z

←Older revision		Revision as of 13:10, 24 November 2021
Line 3:		Line 3:
	<StructureSection load='2bih' size='340' side='right'caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2bih' size='340' side='right'caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bii\|2bii]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [~~http~~://pdbe.org/2bih PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bih PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bih ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [https://pdbe.org/2bih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [https://www.ebi.ac.uk/pdbsum/2bih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NIA_PICAN NIA_PICAN]] Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	+	[[https://www.uniprot.org/uniprot/NIA_PICAN NIA_PICAN]] Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:59, 19 February 2020

2020-02-19T07:59:24Z

←Older revision		Revision as of 07:59, 19 February 2020
Line 1:		Line 1:

	==crystal structure of the Molybdenum-containing nitrate reducing fragment of Pichia angusta assimilatory nitrate reductase==		==crystal structure of the Molybdenum-containing nitrate reducing fragment of Pichia angusta assimilatory nitrate reductase==
-	<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='2bih' size='340' side='right'caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
Line 37:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Barbier, G]]		[[Category: Barbier, G]]
	[[Category: Campbell, W H]]		[[Category: Campbell, W H]]

OCA at 06:20, 16 May 2018

2018-05-16T06:20:27Z

←Older revision		Revision as of 06:20, 16 May 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF THE MOLYBDENUM~~-~~CONTAINING NITRATE REDUCING FRAGMENT OF PICHIA ANGUSTA ASSIMILATORY NITRATE REDUCTASE~~==	+
		+	==crystal structure of the Molybdenum-containing nitrate reducing fragment of Pichia angusta assimilatory nitrate reductase==
	<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://pdbe.org/2bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://pdbe.org/2bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bih ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/2bih_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/2bih_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:19, 7 February 2016

2016-02-07T18:19:46Z

←Older revision		Revision as of 18:19, 7 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bih ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:59, 10 September 2015

2015-09-10T03:59:16Z

←Older revision		Revision as of 03:59, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://pdbe.org/2bih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2bih" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ogataea angusta]]
	[[Category: Barbier, G]]		[[Category: Barbier, G]]
	[[Category: Campbell, W H]]		[[Category: Campbell, W H]]

OCA at 17:22, 24 December 2014

2014-12-24T17:22:59Z

←Older revision		Revision as of 17:22, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NIA_PICAN NIA_PICAN]] Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Ogataea angusta]]		[[Category: Ogataea angusta]]
-	[[Category: Barbier, G.]]	+	[[Category: Barbier, G]]
-	[[Category: Campbell, W H.]]	+	[[Category: Campbell, W H]]
-	[[Category: Fischer, K.]]	+	[[Category: Fischer, K]]
-	[[Category: Hecht, H J.]]	+	[[Category: Hecht, H J]]
-	[[Category: Mendel, R R.]]	+	[[Category: Mendel, R R]]
-	[[Category: Schwarz, G.]]	+	[[Category: Schwarz, G]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
	[[Category: Nitrate assimilation]]		[[Category: Nitrate assimilation]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 08:24, 3 October 2014

2014-10-03T08:24:55Z

←Older revision		Revision as of 08:24, 3 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2bih.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE MOLYBDENUM-CONTAINING NITRATE REDUCING FRAGMENT OF PICHIA ANGUSTA ASSIMILATORY NITRATE REDUCTASE==
		+	<StructureSection load='2bih' size='340' side='right' caption='[[2bih]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2bih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTV:(MOLYBDOPTERIN-S,S)-DIOXO-THIO-MOLYBDENUM(IV)'>MTV</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bii\|2bii]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrate_reductase_(NAD(P)H) Nitrate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.2 1.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bih RCSB], [http://www.ebi.ac.uk/pdbsum/2bih PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/2bih_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Nitrate assimilation in autotrophs provides most of the reduced nitrogen on earth. In eukaryotes, reduction of nitrate to nitrite is catalyzed by the molybdenum-containing NAD(P)H:nitrate reductase (NR; EC 1.7.1.1-3). In addition to the molybdenum center, NR contains iron-heme and flavin adenine dinucleotide as redox cofactors involved in an internal electron transport chain from NAD(P)H to nitrate. Recombinant, catalytically active Pichia angusta nitrate-reducing, molybdenum-containing fragment (NR-Mo) was expressed in P. pastoris and purified. Crystal structures for NR-Mo were determined at 1.7 and 2.6 angstroms. These structures revealed a unique slot for binding nitrate in the active site and identified key Arg and Trp residues potentially involved in nitrate binding. Dimeric NR-Mo is similar in overall structure to sulfite oxidases, with significant differences in the active site. Sulfate bound in the active site caused conformational changes, as compared with the unbound enzyme. Four ordered water molecules located in close proximity to Mo define a nitrate binding site, a penta-coordinated reaction intermediate, and product release. Because yeast NAD(P)H:NR is representative of the family of eukaryotic NR, we propose a general mechanism for nitrate reduction catalysis.

-	~~{{STRUCTURE_2bih\| PDB=2bih \| SCENE= }}~~	+	Structural basis of eukaryotic nitrate reduction: crystal structures of the nitrate reductase active site.,Fischer K, Barbier GG, Hecht HJ, Mendel RR, Campbell WH, Schwarz G Plant Cell. 2005 Apr;17(4):1167-79. Epub 2005 Mar 16. PMID:15772287<ref>PMID:15772287</ref>

-	~~===CRYSTAL STRUCTURE OF THE MOLYBDENUM-CONTAINING NITRATE REDUCING FRAGMENT OF PICHIA ANGUSTA ASSIMILATORY NITRATE REDUCTASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15772287}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2bih]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ogataea_angusta Ogataea angusta]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA].~~	+

	==See Also==		==See Also==
	*[[Nitrate reductase\|Nitrate reductase]]		*[[Nitrate reductase\|Nitrate reductase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015772287<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Ogataea angusta]]		[[Category: Ogataea angusta]]
	[[Category: Barbier, G.]]		[[Category: Barbier, G.]]

OCA at 07:30, 20 October 2012

2012-10-20T07:30:13Z

←Older revision		Revision as of 07:30, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2bih]] is a 1 chain structure ~~of [[Nitrate reductase]]~~ with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA].	+	[[2bih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIH OCA].

	==See Also==		==See Also==

OCA: Protected "2bih" [edit=sysop:move=sysop]

2012-07-25T16:31:53Z

Protected "2bih" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:31, 25 July 2012