2bq5 - Revision history

OCA at 13:52, 13 December 2023

2023-12-13T13:52:26Z

←Older revision		Revision as of 13:52, 13 December 2023
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	<StructureSection load='2bq5' size='340' side='right'caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>		<StructureSection load='2bq5' size='340' side='right'caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacteriophage_ms2 Bacteriophage ms2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1aq3\|1aq3]]~~, [[~~1aq4~~\|~~1aq4~~]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</div></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.91Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [https://pdbe.org/2bq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2bq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bq5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [https://pdbe.org/2bq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2bq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bq5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~COAT_BPMS2 COAT_BPMS2~~]~~] Forms~~ the ~~phage~~ shell~~; binds~~ to the ~~phage~~ RNA.	+	[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteriophage ms2~~]]	+	[[Category: Escherichia phage MS2]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Adams~~, C J~~]]	+	[[Category: Adams CJ]]
-	[[Category: Baron~~, A J~~]]	+	[[Category: Baron AJ]]
-	[[Category: Grahn, E]]	+	[[Category: Grahn E]]
-	[[Category: Helgstrand, C]]	+	[[Category: Helgstrand C]]
-	[[Category: Horn~~, W T~~]]	+	[[Category: Horn WT]]
-	[[Category: Lago, H]]	+	[[Category: Lago H]]
-	[[Category: Liljas, L]]	+	[[Category: Liljas L]]
-	[[Category: Peabody~~, D S~~]]	+	[[Category: Peabody DS]]
-	[[Category: Phillips~~, S E.V~~]]	+	[[Category: Phillips SEV]]
-	[[Category: Stockley~~, P G~~]]	+	[[Category: Stockley PG]]
-	[[Category: Stonehouse~~, N J~~]]	+	[[Category: Stonehouse NJ]]
-	[[Category: Tars, K]]	+	[[Category: Tars K]]
-	~~[[Category: Capsid]]~~	+
-	~~[[Category: Hairpin]]~~	+
-	~~[[Category: Icosahedral virus]]~~	+
-	~~[[Category: Levivirus]]~~	+
-	~~[[Category: Virus coat protein]]~~	+
-	~~[[Category: Virus-rna complex]]~~	+
-	~~[[Category: Virus/rna]]~~	+
-	~~[[Category: Virus/viral protein/rna~~]]	+

OCA at 13:39, 13 October 2021

2021-10-13T13:39:06Z

←Older revision		Revision as of 13:39, 13 October 2021
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	<StructureSection load='2bq5' size='340' side='right'caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>		<StructureSection load='2bq5' size='340' side='right'caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [~~http~~://pdbe.org/2bq5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bq5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bq5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [https://pdbe.org/2bq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2bq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bq5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.	+	[[https://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:19, 11 December 2019

2019-12-11T19:19:50Z

←Older revision		Revision as of 19:19, 11 December 2019
Line 1:		Line 1:

	==MS2 (N87AE89K mutant) - RNA hairpin complex==		==MS2 (N87AE89K mutant) - RNA hairpin complex==
-	<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>	+	<StructureSection load='2bq5' size='340' side='right'caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage ms2]]		[[Category: Bacteriophage ms2]]
		+	[[Category: Large Structures]]
	[[Category: Adams, C J]]		[[Category: Adams, C J]]
	[[Category: Baron, A J]]		[[Category: Baron, A J]]

OCA at 07:18, 17 January 2018

2018-01-17T07:18:58Z

←Older revision		Revision as of 07:18, 17 January 2018
Line 1:		Line 1:
-	==MS2 (N87AE89K ~~MUTANT~~) - RNA ~~HAIRPIN COMPLEX~~==	+
		+	==MS2 (N87AE89K mutant) - RNA hairpin complex==
	<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>		<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://pdbe.org/2bq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://pdbe.org/2bq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bq5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/2bq5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/2bq5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bq5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:14, 11 September 2015

2015-09-11T15:14:41Z

←Older revision		Revision as of 15:14, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>		<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacterio_phage_ms2 Enterobacterio phage~~ ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://pdbe.org/2bq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2bq5" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacterio phage~~ ms2]]	+	[[Category: Bacteriophage ms2]]
	[[Category: Adams, C J]]		[[Category: Adams, C J]]
	[[Category: Baron, A J]]		[[Category: Baron, A J]]

OCA at 18:14, 25 December 2014

2014-12-25T18:14:45Z

←Older revision		Revision as of 18:14, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
-	[[Category: Adams, C J.]]	+	[[Category: Adams, C J]]
-	[[Category: Baron, A J.]]	+	[[Category: Baron, A J]]
-	[[Category: Grahn, E.]]	+	[[Category: Grahn, E]]
-	[[Category: Helgstrand, C.]]	+	[[Category: Helgstrand, C]]
-	[[Category: Horn, W T.]]	+	[[Category: Horn, W T]]
-	[[Category: Lago, H.]]	+	[[Category: Lago, H]]
-	[[Category: Liljas, L.]]	+	[[Category: Liljas, L]]
-	[[Category: Peabody, D S.]]	+	[[Category: Peabody, D S]]
-	[[Category: Phillips, S E.V.]]	+	[[Category: Phillips, S E.V]]
-	[[Category: Stockley, P G.]]	+	[[Category: Stockley, P G]]
-	[[Category: Stonehouse, N J.]]	+	[[Category: Stonehouse, N J]]
-	[[Category: Tars, K.]]	+	[[Category: Tars, K]]
	[[Category: Capsid]]		[[Category: Capsid]]
	[[Category: Hairpin]]		[[Category: Hairpin]]

OCA at 11:10, 3 October 2014

2014-10-03T11:10:40Z

←Older revision		Revision as of 11:10, 3 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2bq5.~~png~~\|~~left~~\|200px]]	+	==MS2 (N87AE89K MUTANT) - RNA HAIRPIN COMPLEX==
		+	<StructureSection load='2bq5' size='340' side='right' caption='[[2bq5]], [[Resolution\|resolution]] 2.91Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BQ5 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1gkv\|1gkv]], [[1gkw\|1gkw]], [[1kuo\|1kuo]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[2bny\|2bny]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2bq5 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/2bq5_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sequence-specific interactions between RNA stem-loops and coat protein (CP) subunits play vital roles in the life cycles of the RNA bacteriophages, e.g., by allowing translational repression of their replicase cistrons and tagging their own RNA genomes for encapsidation. The CPs of bacteriophages Qbeta and MS2 each discriminate in favor of their cognate translational operators, even in the presence of closely related operators from other phages in vivo. Discrete mutations within the MS2 CP have been shown to relax this discrimination in vitro. We have determined the structures of eight complexes between such mutants and both MS2 and Qbeta stem-loops with X-ray crystallography. In conjunction with previously determined in vivo repression data, the structures enable us to propose the molecular basis for the discrimination mechanism.

-	~~{{STRUCTURE_2bq5\| PDB=2bq5 \| SCENE= }}~~	+	Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2.,Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ, Lago H, Adams CJ, Peabody DS, Phillips SE, Stonehouse NJ, Liljas L, Stockley PG Structure. 2006 Mar;14(3):487-95. PMID:16531233<ref>PMID:16531233</ref>

-	~~===MS2 (N87AE89K MUTANT) - RNA HAIRPIN COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16531233}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2bq5]] is~~ a ~~5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016531233<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J.]]

OCA: Protected "2bq5" [edit=sysop:move=sysop]

2013-01-06T11:01:50Z

Protected "2bq5" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:01, 6 January 2013

OCA at 11:01, 6 January 2013

2013-01-06T11:01:47Z

←Older revision		Revision as of 11:01, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2bq5.png\|left\|200px]]		[[Image:2bq5.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2bq5", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2bq5\| PDB=2bq5 \| SCENE= }}		{{STRUCTURE_2bq5\| PDB=2bq5 \| SCENE= }}

-	===MS2 (N87AE89K MUTANT)- RNA HAIRPIN COMPLEX===	+	===MS2 (N87AE89K MUTANT) - RNA HAIRPIN COMPLEX===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16531233}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16531233 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16531233}}		{{ABSTRACT_PUBMED_16531233}}

	==About this Structure==		==About this Structure==
-	~~2BQ5~~ is a 5 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA].	+	[[2bq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16531233~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016531233</ref><references group="xtra"/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J.]]
Line 42:		Line 30:
	[[Category: Levivirus]]		[[Category: Levivirus]]
	[[Category: Virus coat protein]]		[[Category: Virus coat protein]]
		+	[[Category: Virus-rna complex]]
		+	[[Category: Virus/rna]]
	[[Category: Virus/viral protein/rna]]		[[Category: Virus/viral protein/rna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:49:34 2009''

OCA at 23:49, 17 February 2009

2009-02-17T23:49:35Z

←Older revision		Revision as of 23:49, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2BQ5 is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA].	+	2BQ5 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BQ5 OCA].

	==Reference==		==Reference==
-	Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2., Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ, Lago H, Adams CJ, Peabody DS, Phillips SE, Stonehouse NJ, Liljas L, Stockley PG, Structure. 2006 Mar;14(3):487-95. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16531233 16531233]~~	+	<ref group="xtra">PMID:16531233</ref><references group="xtra"/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
-	[[Category: Protein complex]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J.]]
	[[Category: Baron, A J.]]		[[Category: Baron, A J.]]
Line 45:		Line 44:
	[[Category: Virus/viral protein/rna]]		[[Category: Virus/viral protein/rna]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 08~~:42:~~39 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:49:34 2009''