2bv3 - Revision history

OCA at 13:56, 13 December 2023

2023-12-13T13:56:22Z

←Older revision		Revision as of 13:56, 13 December 2023
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	<StructureSection load='2bv3' size='340' side='right'caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2bv3' size='340' side='right'caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID~~-~~GUANYLATE+ESTER'>GNP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1dar\|1dar]]~~, [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [https://pdbe.org/2bv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2bv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [https://pdbe.org/2bv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2bv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	+	[https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gudkov~~, A T~~]]	+	[[Category: Thermus thermophilus]]
-	[[Category: Hansson, S]]	+	[[Category: Gudkov AT]]
-	[[Category: Liljas, A]]	+	[[Category: Hansson S]]
-	[[Category: Logan~~, D T~~]]	+	[[Category: Liljas A]]
-	[[Category: Singh, R]]	+	[[Category: Logan DT]]
-	~~[[Category: Elongation factor]]~~	+	[[Category: Singh R]]
-	~~[[Category: Gtp-binding]]~~	+
-	~~[[Category: Protein biosynthesis]]~~	+
-	~~[[Category: Switch ii]]~~	+
-	~~[[Category: Translation mutation thr84ala~~]]	+

OCA at 13:40, 13 October 2021

2021-10-13T13:40:06Z

←Older revision		Revision as of 13:40, 13 October 2021
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	<StructureSection load='2bv3' size='340' side='right'caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2bv3' size='340' side='right'caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [~~http~~://pdbe.org/2bv3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bv3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [https://pdbe.org/2bv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2bv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	+	[[https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:06, 11 December 2019

2019-12-11T19:06:21Z

←Older revision		Revision as of 19:06, 11 December 2019
Line 1:		Line 1:

	==Crystal structure of a mutant elongation factor G trapped with a GTP analogue==		==Crystal structure of a mutant elongation factor G trapped with a GTP analogue==
-	<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2bv3' size='340' side='right'caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2bv3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2bv3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Elongation factor 3D structures\|Elongation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]		[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
		+	[[Category: Large Structures]]
	[[Category: Gudkov, A T]]		[[Category: Gudkov, A T]]
	[[Category: Hansson, S]]		[[Category: Hansson, S]]

OCA at 07:19, 17 January 2018

2018-01-17T07:19:14Z

←Older revision		Revision as of 07:19, 17 January 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF A MUTANT ELONGATION FACTOR~~ G ~~TRAPPED WITH A~~ GTP ~~ANALOGUE~~==	+
		+	==Crystal structure of a mutant elongation factor G trapped with a GTP analogue==
	<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://pdbe.org/2bv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://pdbe.org/2bv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2bv3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2bv3" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Elongation factor\|Elongation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:17, 9 February 2016

2016-02-09T18:17:02Z

←Older revision		Revision as of 18:17, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bv3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:48, 11 September 2015

2015-09-11T00:48:00Z

←Older revision		Revision as of 00:48, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://pdbe.org/2bv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2bv3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Gudkov, A T]]		[[Category: Gudkov, A T]]
	[[Category: Hansson, S]]		[[Category: Hansson, S]]

OCA at 08:36, 25 December 2014

2014-12-25T08:36:47Z

←Older revision		Revision as of 08:36, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Gudkov, A T.]]	+	[[Category: Gudkov, A T]]
-	[[Category: Hansson, S.]]	+	[[Category: Hansson, S]]
-	[[Category: Liljas, A.]]	+	[[Category: Liljas, A]]
-	[[Category: Logan, D T.]]	+	[[Category: Logan, D T]]
-	[[Category: Singh, R.]]	+	[[Category: Singh, R]]
	[[Category: Elongation factor]]		[[Category: Elongation factor]]
	[[Category: Gtp-binding]]		[[Category: Gtp-binding]]

OCA at 03:52, 29 September 2014

2014-09-29T03:52:05Z

←Older revision		Revision as of 03:52, 29 September 2014
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-	[[~~Image:~~2bv3.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF A MUTANT ELONGATION FACTOR G TRAPPED WITH A GTP ANALOGUE==
		+	<StructureSection load='2bv3' size='340' side='right' caption='[[2bv3]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dar\|1dar]], [[1efg\|1efg]], [[1elo\|1elo]], [[1fnm\|1fnm]], [[1ip8\|1ip8]], [[1ipm\|1ipm]], [[1ipo\|1ipo]], [[1ipr\|1ipr]], [[1jqm\|1jqm]], [[1jqs\|1jqs]], [[1ktv\|1ktv]], [[1pn6\|1pn6]], [[2efg\|2efg]], [[2bm1\|2bm1]], [[2bm0\|2bm0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bv3 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Elongation factor G (EF-G) is a G protein factor that catalyzes the translocation step in protein synthesis on the ribosome. Its GTP conformation in the absence of the ribosome is currently unknown. We present the structure of a mutant EF-G (T84A) in complex with the non-hydrolysable GTP analogue GDPNP. The crystal structure provides a first insight into conformational changes induced in EF-G by GTP. Comparison of this structure with that of EF-G in complex with GDP suggests that the GTP and GDP conformations in solution are very similar and that the major contribution to the active GTPase conformation, which is quite different, therefore comes from its interaction with the ribosome.

-	~~{{STRUCTURE_2bv3\| PDB=2bv3 \| SCENE= }}~~	+	Crystal structure of a mutant elongation factor G trapped with a GTP analogue.,Hansson S, Singh R, Gudkov AT, Liljas A, Logan DT FEBS Lett. 2005 Aug 15;579(20):4492-7. PMID:16083884<ref>PMID:16083884</ref>

-	~~===CRYSTAL STRUCTURE OF A MUTANT ELONGATION FACTOR G TRAPPED WITH A GTP ANALOGUE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16083884}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2bv3]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA].~~	+

	==See Also==		==See Also==
	*[[Elongation factor\|Elongation factor]]		*[[Elongation factor\|Elongation factor]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016083884<~~/~~ref~~><~~ref group="xtra">PMID:008070396</ref><ref group="xtra">PMID:011054294</ref><ref group="xtra">PMID:011371559</ref><ref group="xtra">PMID:015843024</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Gudkov, A T.]]		[[Category: Gudkov, A T.]]

OCA at 14:42, 20 October 2012

2012-10-20T14:42:20Z

←Older revision		Revision as of 14:42, 20 October 2012
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	[[Image:2bv3.png\|left\|200px]]		[[Image:2bv3.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2bv3\| PDB=2bv3 \| SCENE= }}		{{STRUCTURE_2bv3\| PDB=2bv3 \| SCENE= }}

	===CRYSTAL STRUCTURE OF A MUTANT ELONGATION FACTOR G TRAPPED WITH A GTP ANALOGUE===		===CRYSTAL STRUCTURE OF A MUTANT ELONGATION FACTOR G TRAPPED WITH A GTP ANALOGUE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16083884}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16083884 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16083884}}		{{ABSTRACT_PUBMED_16083884}}

	==About this Structure==		==About this Structure==
	[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA].		[[2bv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV3 OCA].
		+
		+	==See Also==
		+	*[[Elongation factor\|Elongation factor]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16083884~~</ref><ref group="xtra">PMID:~~8070396~~</ref><ref group="xtra">PMID:~~8070397~~</ref><ref group="xtra">PMID:~~8736554~~</ref><ref group="xtra">PMID:~~11054294</ref><ref group="xtra">PMID:11371559</ref><ref group="xtra">PMID:15843024~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016083884</ref><ref group="xtra">PMID:008070396</ref><ref group="xtra">PMID:011054294</ref><ref group="xtra">PMID:011371559</ref><ref group="xtra">PMID:015843024</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Gudkov, A T.]]		[[Category: Gudkov, A T.]]

OCA: Protected "2bv3" [edit=sysop:move=sysop]

2011-03-14T23:11:29Z

Protected "2bv3" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:11, 14 March 2011