2bvy - Revision history

OCA at 13:56, 13 December 2023

2023-12-13T13:56:50Z

←Older revision		Revision as of 13:56, 13 December 2023
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	<StructureSection load='2bvy' size='340' side='right'caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bvy' size='340' side='right'caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium~~ fimi~~" mcbeth and scales 1913~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BVY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2bvt\|2bvt]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [https://pdbe.org/2bvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [https://www.ebi.ac.uk/pdbsum/2bvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bvy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [https://pdbe.org/2bvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [https://www.ebi.ac.uk/pdbsum/2bvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bvy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9XCV5_CELFI Q9XCV5_CELFI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium fimi mcbeth and scales 1913]]
-	[[Category: Large Structures]]
-	[[Category: Mannan endo-1,4-beta-mannosidase]]
-	[[Category: Anderson, L]]
-	[[Category: Leggio, L Lo]]
-	[[Category: Nours, J Le]]
-	[[Category: Stalbrand, H]]
-	[[Category: Stoll, D]]
-	[[Category: 4-mannanase]]
-	[[Category: Beta-1]]
	[[Category: Cellulomonas fimi]]		[[Category: Cellulomonas fimi]]
-	[[Category: ~~Clan gh-a~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Family 26~~]]	+	[[Category: Anderson L]]
-	[[Category: ~~Glycoside hydrolase~~]]	+	[[Category: Le Nours J]]
-	[[Category: ~~Hydrolase~~]]	+	[[Category: Lo Leggio L]]
		+	[[Category: Stalbrand H]]
		+	[[Category: Stoll D]]

OCA at 13:18, 24 November 2021

2021-11-24T13:18:55Z

←Older revision		Revision as of 13:18, 24 November 2021
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	<StructureSection load='2bvy' size='340' side='right'caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bvy' size='340' side='right'caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium fimi" mcbeth and scales 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BVY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium fimi" mcbeth and scales 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bvt\|2bvt]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [~~http~~://pdbe.org/2bvy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bvy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bvy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [https://pdbe.org/2bvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [https://www.ebi.ac.uk/pdbsum/2bvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bvy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:21, 19 February 2020

2020-02-19T08:21:11Z

←Older revision		Revision as of 08:21, 19 February 2020
Line 1:		Line 1:

	==The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi==		==The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi==
-	<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='2bvy' size='340' side='right'caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium fimi" mcbeth and scales 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium fimi" mcbeth and scales 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium fimi mcbeth and scales 1913]]		[[Category: Bacterium fimi mcbeth and scales 1913]]
		+	[[Category: Large Structures]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
	[[Category: Anderson, L]]		[[Category: Anderson, L]]

OCA at 06:54, 16 May 2018

2018-05-16T06:54:33Z

←Older revision		Revision as of 06:54, 16 May 2018
Line 1:		Line 1:
-	==~~THE STRUCTURE AND CHARACTERIZATION OF A MODULAR ENDO~~-~~BETA~~-1,4-~~MANNANASE FROM CELLULOMONAS FIMI~~==	+
		+	==The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi==
	<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://pdbe.org/2bvy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://pdbe.org/2bvy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bvy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bvy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bvy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:53, 7 February 2016

2016-02-07T09:53:58Z

←Older revision		Revision as of 09:53, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bvy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:19, 10 September 2015

2015-09-10T00:19:26Z

←Older revision		Revision as of 00:19, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cellulomonas_fimi Cellulomonas~~ fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_fimi"_mcbeth_and_scales_1913 "bacterium fimi" mcbeth and scales 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://pdbe.org/2bvy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2bvy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cellulomonas~~ fimi]]	+	[[Category: Bacterium fimi mcbeth and scales 1913]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
	[[Category: Anderson, L]]		[[Category: Anderson, L]]
Line 39:		Line 40:
	[[Category: 4-mannanase]]		[[Category: 4-mannanase]]
	[[Category: Beta-1]]		[[Category: Beta-1]]
		+	[[Category: Cellulomonas fimi]]
	[[Category: Clan gh-a]]		[[Category: Clan gh-a]]
	[[Category: Family 26]]		[[Category: Family 26]]
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 18:40, 15 January 2015

2015-01-15T18:40:37Z

←Older revision		Revision as of 18:40, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: Cellulomonas fimi]]		[[Category: Cellulomonas fimi]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
-	[[Category: Anderson, L.]]	+	[[Category: Anderson, L]]
-	[[Category: Leggio, L Lo.]]	+	[[Category: Leggio, L Lo]]
-	[[Category: Nours, J Le.]]	+	[[Category: Nours, J Le]]
-	[[Category: Stalbrand, H.]]	+	[[Category: Stalbrand, H]]
-	[[Category: Stoll, D.]]	+	[[Category: Stoll, D]]
	[[Category: 4-mannanase]]		[[Category: 4-mannanase]]
	[[Category: Beta-1]]		[[Category: Beta-1]]
-	[[Category: Cellulomonas fimi]]
	[[Category: Clan gh-a]]		[[Category: Clan gh-a]]
	[[Category: Family 26]]		[[Category: Family 26]]
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 03:05, 30 September 2014

2014-09-30T03:05:43Z

←Older revision		Revision as of 03:05, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2bvy.~~png~~\|~~left~~\|200px]]	+	==THE STRUCTURE AND CHARACTERIZATION OF A MODULAR ENDO-BETA-1,4-MANNANASE FROM CELLULOMONAS FIMI==
		+	<StructureSection load='2bvy' size='340' side='right' caption='[[2bvy]], [[Resolution\|resolution]] 2.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BVY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvt\|2bvt]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bvy RCSB], [http://www.ebi.ac.uk/pdbsum/2bvy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bvy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The endo-beta-1,4-mannanase from the soil bacterium Cellulomonas fimi is a modular plant cell wall degrading enzyme involved in the hydrolysis of the backbone of mannan, one of the most abundant polysaccharides of the hemicellulosic network in the plant cell wall. The crystal structure of a recombinant truncated endo-beta-1,4-mannanase from C. fimi (CfMan26A-50K) was determined by X-ray crystallography to 2.25 A resolution using the molecular replacement technique. The overall structure of the enzyme consists of a core (beta/alpha)8-barrel catalytic module characteristic of clan GH-A, connected via a linker to an immunoglobulin-like module of unknown function. A complex with the oligosaccharide mannotriose to 2.9 A resolution has also been obtained. Both the native structure and the complex show a cacodylate ion bound at the -1 subsite, while subsites -2, -3, and -4 are occupied by mannotriose in the complex. Enzyme kinetic analysis and the analysis of hydrolysis products from manno-oligosaccharides and mannopentitol suggest five important active-site cleft subsites. CfMan26A-50K has a high affinity -3 subsite with Phe325 as an aromatic platform, which explains the mannose releasing property of the enzyme. Structural differences with the homologous Cellvibrio japonicus beta-1,4-mannanase (CjMan26A) at the -2 and -3 subsites may explain the poor performance of CfMan26A mutants as "glycosynthases".

-	~~{{STRUCTURE_2bvy\| PDB=2bvy \| SCENE= }}~~	+	The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi.,Le Nours J, Anderson L, Stoll D, Stalbrand H, Lo Leggio L Biochemistry. 2005 Sep 27;44(38):12700-8. PMID:16171384<ref>PMID:16171384</ref>

-	~~===THE STRUCTURE AND CHARACTERIZATION OF A MODULAR ENDO-BETA-1~~,~~4-MANNANASE FROM CELLULOMONAS FIMI===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16171384}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2bvy]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Cellulomonas_fimi Cellulomonas fimi]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016171384<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Cellulomonas fimi]]		[[Category: Cellulomonas fimi]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]

OCA: Protected "2bvy" [edit=sysop:move=sysop]

2013-01-06T12:15:11Z

Protected "2bvy" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:15, 6 January 2013

OCA at 12:15, 6 January 2013

2013-01-06T12:15:08Z

←Older revision		Revision as of 12:15, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2bvy.png\|left\|200px]]		[[Image:2bvy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2bvy", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2bvy\| PDB=2bvy \| SCENE= }}		{{STRUCTURE_2bvy\| PDB=2bvy \| SCENE= }}

	===THE STRUCTURE AND CHARACTERIZATION OF A MODULAR ENDO-BETA-1,4-MANNANASE FROM CELLULOMONAS FIMI===		===THE STRUCTURE AND CHARACTERIZATION OF A MODULAR ENDO-BETA-1,4-MANNANASE FROM CELLULOMONAS FIMI===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16171384}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16171384 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16171384}}		{{ABSTRACT_PUBMED_16171384}}

	==About this Structure==		==About this Structure==
-	~~2BVY~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA].	+	[[2bvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BVY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16171384~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016171384</ref><references group="xtra"/>
	[[Category: Cellulomonas fimi]]		[[Category: Cellulomonas fimi]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
Line 31:		Line 19:
	[[Category: Stalbrand, H.]]		[[Category: Stalbrand, H.]]
	[[Category: Stoll, D.]]		[[Category: Stoll, D.]]
		+	[[Category: 4-mannanase]]
		+	[[Category: Beta-1]]
	[[Category: Cellulomonas fimi]]		[[Category: Cellulomonas fimi]]
	[[Category: Clan gh-a]]		[[Category: Clan gh-a]]
-	[[Category: ~~Glycoside hydrolase,beta-1,4-mannanase,family~~ 26]]	+	[[Category: Family 26]]
-		+	[[Category: Glycoside hydrolase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 13~~:~~01:11 2009''~~	+	[[Category: Hydrolase]]