2bym - Revision history

OCA at 09:20, 9 May 2024

2024-05-09T09:20:24Z

←Older revision		Revision as of 09:20, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2bym' size='340' side='right'caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2bym' size='340' side='right'caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BYM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2byk\|2byk]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [https://pdbe.org/2bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [https://www.ebi.ac.uk/pdbsum/2bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bym ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [https://pdbe.org/2bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [https://www.ebi.ac.uk/pdbsum/2bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bym ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CHRC_DROME CHRC_DROME] Histone-like protein which promotes nucleosome sliding of ATP-dependent nucleosome remodeling complexes (PubMed:10856248, PubMed:11447119). Part of the chromatin-accessibility complex (CHRAC) which uses energy/ATP to increase the general accessibility of DNA in chromatin (PubMed:10856248, PubMed:11447119). As an heterodimer with Chrac-14, binds DNA and facilitates nucleosome sliding by Acf (PubMed:16260604). As part of the CHRAC complex, required for oogenesis (PubMed:26851213).<ref>PMID:10856248</ref> <ref>PMID:11447119</ref> <ref>PMID:16260604</ref> <ref>PMID:26851213</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drome~~]]	+	[[Category: Drosophila melanogaster]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Becker~~, P B~~]]	+	[[Category: Becker PB]]
-	[[Category: Eberharter, A]]	+	[[Category: Eberharter A]]
-	[[Category: Fernandez-Tornero, C]]	+	[[Category: Fernandez-Tornero C]]
-	[[Category: Grune, T]]	+	[[Category: Grune T]]
-	[[Category: Hartlepp~~, K F~~]]	+	[[Category: Hartlepp KF]]
-	[[Category: Muller~~, C W]]~~	+	[[Category: Muller CW]]
-	~~[[Category: Chrac-14]]~~	+
-	~~[[Category: Chrac-16]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Dna-binding protein]]~~	+
-	~~[[Category: Histone fold]]~~	+
-	~~[[Category: Nucleosome sliding~~]]	+

OCA at 13:20, 24 November 2021

2021-11-24T13:20:49Z

←Older revision		Revision as of 13:20, 24 November 2021
Line 3:		Line 3:
	<StructureSection load='2bym' size='340' side='right'caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2bym' size='340' side='right'caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BYM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2byk\|2byk]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [~~http~~://pdbe.org/2bym PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bym PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bym ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [https://pdbe.org/2bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [https://www.ebi.ac.uk/pdbsum/2bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bym ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:02, 19 February 2020

2020-02-19T08:02:09Z

←Older revision		Revision as of 08:02, 19 February 2020
Line 1:		Line 1:

	==Histone fold heterodimer of the Chromatin Accessibility Complex==		==Histone fold heterodimer of the Chromatin Accessibility Complex==
-	<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='2bym' size='340' side='right'caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Drome]]		[[Category: Drome]]
		+	[[Category: Large Structures]]
	[[Category: Becker, P B]]		[[Category: Becker, P B]]
	[[Category: Eberharter, A]]		[[Category: Eberharter, A]]

OCA at 06:25, 16 May 2018

2018-05-16T06:25:16Z

←Older revision		Revision as of 06:25, 16 May 2018
Line 1:		Line 1:
-	==~~HISTONE FOLD HETERODIMER OF THE CHROMATIN ACCESSIBILITY COMPLEX~~==	+
		+	==Histone fold heterodimer of the Chromatin Accessibility Complex==
	<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://pdbe.org/2bym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://pdbe.org/2bym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bym ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/by/2bym_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/by/2bym_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bym ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 39:		Line 40:
	[[Category: Chrac-14]]		[[Category: Chrac-14]]
	[[Category: Chrac-16]]		[[Category: Chrac-16]]
		+	[[Category: Dna binding protein]]
	[[Category: Dna-binding protein]]		[[Category: Dna-binding protein]]
	[[Category: Histone fold]]		[[Category: Histone fold]]
	[[Category: Nucleosome sliding]]		[[Category: Nucleosome sliding]]

OCA at 08:24, 11 September 2015

2015-09-11T08:24:43Z

←Older revision		Revision as of 08:24, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://pdbe.org/2bym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2bym" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drosophila melanogaster~~]]	+	[[Category: Drome]]
	[[Category: Becker, P B]]		[[Category: Becker, P B]]
	[[Category: Eberharter, A]]		[[Category: Eberharter, A]]

OCA at 17:47, 15 January 2015

2015-01-15T17:47:24Z

←Older revision		Revision as of 17:47, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Becker, P B.]]	+	[[Category: Becker, P B]]
-	[[Category: Eberharter, A.]]	+	[[Category: Eberharter, A]]
-	[[Category: Fernandez-Tornero, C.]]	+	[[Category: Fernandez-Tornero, C]]
-	[[Category: Grune, T.]]	+	[[Category: Grune, T]]
-	[[Category: Hartlepp, K F.]]	+	[[Category: Hartlepp, K F]]
-	[[Category: Muller, C W.]]	+	[[Category: Muller, C W]]
	[[Category: Chrac-14]]		[[Category: Chrac-14]]
	[[Category: Chrac-16]]		[[Category: Chrac-16]]

OCA at 00:55, 30 September 2014

2014-09-30T00:55:09Z

←Older revision		Revision as of 00:55, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2bym.~~png~~\|~~left~~\|200px]]	+	==HISTONE FOLD HETERODIMER OF THE CHROMATIN ACCESSIBILITY COMPLEX==
		+	<StructureSection load='2bym' size='340' side='right' caption='[[2bym]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BYM FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byk\|2byk]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bym RCSB], [http://www.ebi.ac.uk/pdbsum/2bym PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/by/2bym_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The chromatin accessibility complex (CHRAC) is an abundant, evolutionarily conserved nucleosome remodeling machinery able to catalyze histone octamer sliding on DNA. CHRAC differs from the related ACF complex by the presence of two subunits with molecular masses of 14 and 16 kDa, whose structure and function were not known. We determined the structure of Drosophila melanogaster CHRAC14-CHRAC16 by X-ray crystallography at 2.4-angstroms resolution and found that they dimerize via a variant histone fold in a typical handshake structure. In further analogy to histones, CHRAC14-16 contain unstructured N- and C-terminal tail domains that protrude from the handshake structure. A dimer of CHRAC14-16 can associate with the N terminus of ACF1, thereby completing CHRAC. Low-affinity interactions of CHRAC14-16 with DNA significantly improve the efficiency of nucleosome mobilization by limiting amounts of ACF. Deletion of the negatively charged C terminus of CHRAC16 enhances DNA binding 25-fold but leads to inhibition of nucleosome sliding, in striking analogy to the effect of the DNA chaperone HMGB1 on nucleosome sliding. The presence of a surface compatible with DNA interaction and the geometry of an H2A-H2B heterodimer may provide a transient acceptor site for DNA dislocated from the histone surface and therefore facilitate the nucleosome remodeling process.

-	~~{{STRUCTURE_2bym\| PDB=2bym \| SCENE= }}~~	+	The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions.,Hartlepp KF, Fernandez-Tornero C, Eberharter A, Grune T, Muller CW, Becker PB Mol Cell Biol. 2005 Nov;25(22):9886-96. PMID:16260604<ref>PMID:16260604</ref>

-	~~===HISTONE FOLD HETERODIMER OF THE CHROMATIN ACCESSIBILITY COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16260604}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2bym]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Drosophila_melanogaster Drosophila melanogaster]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016260604<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Becker, P B.]]		[[Category: Becker, P B.]]

OCA: Protected "2bym" [edit=sysop:move=sysop]

2013-01-06T10:13:58Z

Protected "2bym" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:13, 6 January 2013

OCA at 10:13, 6 January 2013

2013-01-06T10:13:53Z

←Older revision		Revision as of 10:13, 6 January 2013
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-	{{Seed}}
	[[Image:2bym.png\|left\|200px]]		[[Image:2bym.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2bym", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2bym\| PDB=2bym \| SCENE= }}		{{STRUCTURE_2bym\| PDB=2bym \| SCENE= }}

	===HISTONE FOLD HETERODIMER OF THE CHROMATIN ACCESSIBILITY COMPLEX===		===HISTONE FOLD HETERODIMER OF THE CHROMATIN ACCESSIBILITY COMPLEX===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16260604}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16260604 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16260604}}		{{ABSTRACT_PUBMED_16260604}}

	==About this Structure==		==About this Structure==
-	~~2BYM~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA].	+	[[2bym]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16260604~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016260604</ref><references group="xtra"/>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Becker, P B.]]		[[Category: Becker, P B.]]
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	[[Category: Histone fold]]		[[Category: Histone fold]]
	[[Category: Nucleosome sliding]]		[[Category: Nucleosome sliding]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:53:02 2009''

OCA at 15:53, 17 February 2009

2009-02-17T15:53:04Z

←Older revision		Revision as of 15:53, 17 February 2009
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	==About this Structure==		==About this Structure==
-	2BYM is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA].	+	2BYM is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BYM OCA].

	==Reference==		==Reference==
-	The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions., Hartlepp KF, Fernandez-Tornero C, Eberharter A, Grune T, Muller CW, Becker PB, Mol Cell Biol. 2005 Nov;25(22):9886-96. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16260604 16260604]~~	+	<ref group="xtra">PMID:16260604</ref><references group="xtra"/>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Protein complex]]
	[[Category: Becker, P B.]]		[[Category: Becker, P B.]]
	[[Category: Eberharter, A.]]		[[Category: Eberharter, A.]]
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	[[Category: Nucleosome sliding]]		[[Category: Nucleosome sliding]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 00~~:58:~~36 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:53:02 2009''