2c32 - Revision history

OCA at 14:03, 13 December 2023

2023-12-13T14:03:53Z

←Older revision		Revision as of 14:03, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2c32' size='340' side='right'caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>		<StructureSection load='2c32' size='340' side='right'caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C32 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~1ymg~~\|~~1ymg~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 7.01Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [https://pdbe.org/2c32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [https://www.ebi.ac.uk/pdbsum/2c32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c32 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [https://pdbe.org/2c32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [https://www.ebi.ac.uk/pdbsum/2c32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c32 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN]] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>	+	[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bovin~~]]	+	[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Palanivelu~~, D V~~]]	+	[[Category: Palanivelu DV]]
-	[[Category: Schirmer, T]]	+	[[Category: Schirmer T]]
-	~~[[Category: Eye lens]]~~	+
-	~~[[Category: Gap junction]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Mixed micelle]]~~	+
-	~~[[Category: Phosphorylation]]~~	+
-	~~[[Category: Transmembrane~~]]	+

OCA at 06:47, 1 December 2021

2021-12-01T06:47:02Z

←Older revision		Revision as of 06:47, 1 December 2021
Line 3:		Line 3:
	<StructureSection load='2c32' size='340' side='right'caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>		<StructureSection load='2c32' size='340' side='right'caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2C32 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ymg\|1ymg]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [~~http~~://pdbe.org/2c32 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2c32 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2c32 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [https://pdbe.org/2c32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [https://www.ebi.ac.uk/pdbsum/2c32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c32 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN]] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>	+	[[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN]] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:58, 26 February 2020

2020-02-26T10:58:41Z

←Older revision		Revision as of 10:58, 26 February 2020
Line 1:		Line 1:

	==Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D-crystals==		==Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D-crystals==
-	<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>	+	<StructureSection load='2c32' size='340' side='right'caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Aquaporin\|Aquaporin]]	+	*[[Aquaporin 3D structures\|Aquaporin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bovin]]		[[Category: Bovin]]
		+	[[Category: Large Structures]]
	[[Category: Palanivelu, D V]]		[[Category: Palanivelu, D V]]
	[[Category: Schirmer, T]]		[[Category: Schirmer, T]]

OCA at 08:21, 23 May 2018

2018-05-23T08:21:28Z

←Older revision		Revision as of 08:21, 23 May 2018
Line 1:		Line 1:
-	==CO-~~AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN~~-0 ~~OBSERVED IN LOOSELY PACKED~~ 3D-~~CRYSTALS~~==	+
		+	==Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D-crystals==
	<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>		<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://pdbe.org/2c32 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://pdbe.org/2c32 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c32 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/2c32_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/2c32_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:09, 9 February 2016

2016-02-09T15:09:17Z

←Older revision		Revision as of 15:09, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c32 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:26, 10 September 2015

2015-09-10T23:26:41Z

←Older revision		Revision as of 23:26, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>		<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://pdbe.org/2c32 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2c32" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bos taurus~~]]	+	[[Category: Bovin]]
	[[Category: Palanivelu, D V]]		[[Category: Palanivelu, D V]]
	[[Category: Schirmer, T]]		[[Category: Schirmer, T]]

OCA at 07:36, 25 December 2014

2014-12-25T07:36:32Z

←Older revision		Revision as of 07:36, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN]] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
-	[[Category: Palanivelu, D V.]]	+	[[Category: Palanivelu, D V]]
-	[[Category: Schirmer, T.]]	+	[[Category: Schirmer, T]]
	[[Category: Eye lens]]		[[Category: Eye lens]]
	[[Category: Gap junction]]		[[Category: Gap junction]]

OCA at 01:03, 30 September 2014

2014-09-30T01:03:16Z

←Older revision		Revision as of 01:03, 30 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2c32\| PDB=2c32 \| SCENE= }}~~	+	==CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS==
-	===CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS===	+	<StructureSection load='2c32' size='340' side='right' caption='[[2c32]], [[Resolution\|resolution]] 7.01Å' scene=''>
-	~~{{ABSTRACT_PUBMED_16309700}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C32 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ymg\|1ymg]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c32 RCSB], [http://www.ebi.ac.uk/pdbsum/2c32 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/2c32_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aquaporin-0 (AQP0) is the major membrane protein in vertebrate eye lenses. It has been proposed that AQP0 tetramers mediate contact between membranes of adjacent lens fiber cells, which would be consistent with the extraordinarily narrow inter-cellular spacing. We have obtained 3D crystals of recombinant bovine AQP0 that diffract to 7.0 A resolution. The crystal packing was determined by molecular replacement and shows that, within the cubic lattice, AQP0 tetramers are associated head-to-head along their 4-fold axes. Oligomeric states larger than the tetramer were also observed in solution by native gel electrophoresis and analytical ultracentrifugation methods. In the crystals, there are no direct contacts between octamers, and it can thus be inferred that crystalline order is mediated solely by the detergent belts surrounding the membrane protein. Across the tetramer-tetramer interface, extracellular loops A and C interdigitate at the center and the perimeter of the octamer, respectively. The octamer structure is compared with that of the recently determined structure of truncated ovine AQP0 derived from electron diffraction of 2D crystals. Intriguingly, also in these crystals, octamers are observed, but with significantly different relative tetramer-tetramer orientations. The interactions observed in the loosely packed 3D crystals reported here may in fact represent an in vivo association mode between AQP0 tetramers from juxtaposed membranes in the eye lens.

-	~~==About this Structure==~~	+	Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D crystals.,Palanivelu DV, Kozono DE, Engel A, Suda K, Lustig A, Agre P, Schirmer T J Mol Biol. 2006 Jan 27;355(4):605-11. Epub 2005 Nov 8. PMID:16309700<ref>PMID:16309700</ref>
-	~~[[2c32]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bos_taurus Bos taurus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2C32 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Aquaporin\|Aquaporin]]		*[[Aquaporin\|Aquaporin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016309700<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Palanivelu, D V.]]		[[Category: Palanivelu, D V.]]

OCA at 09:54, 11 March 2013

2013-03-11T09:54:55Z

←Older revision		Revision as of 09:54, 11 March 2013
Line 1:		Line 1:
-	[[Image:2c32.png\|left\|200px]]
-
	{{STRUCTURE_2c32\| PDB=2c32 \| SCENE= }}		{{STRUCTURE_2c32\| PDB=2c32 \| SCENE= }}
-
	===CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS===		===CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS===
-
	{{ABSTRACT_PUBMED_16309700}}		{{ABSTRACT_PUBMED_16309700}}

OCA at 10:19, 6 January 2013

2013-01-06T10:19:58Z

←Older revision		Revision as of 10:19, 6 January 2013
Line 1:		Line 1:
	[[Image:2c32.png\|left\|200px]]		[[Image:2c32.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2c32", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2c32\| PDB=2c32 \| SCENE= }}		{{STRUCTURE_2c32\| PDB=2c32 \| SCENE= }}

	===CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS===		===CO-AXIAL ASSOCIATION OF RECOMBINANT EYE LENS AQUAPORIN-0 OBSERVED IN LOOSELY PACKED 3D-CRYSTALS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16309700}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16309700 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16309700}}		{{ABSTRACT_PUBMED_16309700}}

	==About this Structure==		==About this Structure==
-	[[2c32]] is a 1 chain structure ~~of [[Aquaporin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA].	+	[[2c32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C32 OCA].

	==See Also==		==See Also==
-	*[[Aquaporin]]	+	*[[Aquaporin\|Aquaporin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16309700~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016309700</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Palanivelu, D V.]]		[[Category: Palanivelu, D V.]]