2dci - Revision history

OCA at 10:34, 16 August 2023

2023-08-16T10:34:14Z

←Older revision		Revision as of 10:34, 16 August 2023
Line 1:		Line 1:

	==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==		==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==
-	<StructureSection load='2dci' size='340' side='right'caption='[[2dci~~]], [[NMR_Ensembles_of_Models \| 33 NMR models~~]]' scene=''>	+	<StructureSection load='2dci' size='340' side='right'caption='[[2dci]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Hong_Kong/126/1982(H3N2)) Influenza A virus (A/swine/Hong Kong/126/1982(H3N2))]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</div~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [https://pdbe.org/2dci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [https://www.ebi.ac.uk/pdbsum/2dci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dci ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [https://pdbe.org/2dci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [https://www.ebi.ac.uk/pdbsum/2dci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dci ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HEMA_I82A4 HEMA_I82A4]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.	+	[https://www.uniprot.org/uniprot/HEMA_I82A4 HEMA_I82A4] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lai~~, A L~~]]	+	[[Category: Lai AL]]
-	[[Category: Tamm~~, L K]]~~	+	[[Category: Tamm LK]]
-	~~[[Category: Fusion peptide]]~~	+
-	~~[[Category: Ha]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 06:49, 10 November 2021

2021-11-10T06:49:20Z

←Older revision		Revision as of 06:49, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='2dci' size='340' side='right'caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>		<StructureSection load='2dci' size='340' side='right'caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DCI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [~~http~~://pdbe.org/2dci PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dci PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dci ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [https://pdbe.org/2dci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [https://www.ebi.ac.uk/pdbsum/2dci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dci ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HEMA_I82A4 HEMA_I82A4]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.	+	[[https://www.uniprot.org/uniprot/HEMA_I82A4 HEMA_I82A4]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:50, 4 March 2020

2020-03-04T07:50:41Z

←Older revision		Revision as of 07:50, 4 March 2020
Line 1:		Line 1:

	==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==		==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==
-	<StructureSection load='2dci' size='340' side='right' caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>	+	<StructureSection load='2dci' size='340' side='right'caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Hemagglutinin\|Hemagglutinin]]	+	*[[Hemagglutinin 3D structures\|Hemagglutinin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lai, A L]]		[[Category: Lai, A L]]
	[[Category: Tamm, L K]]		[[Category: Tamm, L K]]

OCA at 06:40, 30 May 2018

2018-05-30T06:40:11Z

←Older revision		Revision as of 06:40, 30 May 2018
Line 1:		Line 1:
		+
	==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==		==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==
	<StructureSection load='2dci' size='340' side='right' caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>		<StructureSection load='2dci' size='340' side='right' caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [http://pdbe.org/2dci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [http://www.ebi.ac.uk/pdbsum/2dci PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [http://pdbe.org/2dci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [http://www.ebi.ac.uk/pdbsum/2dci PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dci ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:15, 11 September 2015

2015-09-11T23:15:27Z

←Older revision		Revision as of 23:15, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [http://www.ebi.ac.uk/pdbsum/2dci PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [http://pdbe.org/2dci PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [http://www.ebi.ac.uk/pdbsum/2dci PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HEMA_I82A4 HEMA_I82A4]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2dci" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 13:55, 17 December 2014

2014-12-17T13:55:04Z

←Older revision		Revision as of 13:55, 17 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2dci\| PDB=2dci \| SCENE= }}~~	+	==NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5==
-	===NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5===	+	<StructureSection load='2dci' size='340' side='right' caption='[[2dci]], [[NMR_Ensembles_of_Models \| 33 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_16407195}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCI FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ibn\|1ibn]], [[1ibo\|1ibo]], [[1xoo\|1xoo]], [[1xop\|1xop]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dci RCSB], [http://www.ebi.ac.uk/pdbsum/2dci PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The fusion peptide of influenza hemagglutinin is crucial for cell entry of this virus. Previous studies showed that this peptide adopts a boomerang-shaped structure in lipid model membranes at the pH of membrane fusion. To examine the role of the boomerang in fusion, we changed several residues proposed to stabilize the kink in this structure and measured fusion. Among these, mutants E11A and W14A expressed hemagglutinins with hemifusion and no fusion activities, and F9A and N12A had no effect on fusion, respectively. Binding enthalpies and free energies of mutant peptides to model membranes and their ability to perturb lipid bilayer structures correlated well with the fusion activities of the parent full-length molecules. The structure of W14A determined by NMR and site-directed spin labeling features a flexible kink that points out of the membrane, in sharp contrast to the more ordered boomerang of the wild-type, which points into the membrane. A specific fixed angle boomerang structure is thus required to support membrane fusion.

-	~~==About this Structure==~~	+	Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity.,Lai AL, Park H, White JM, Tamm LK J Biol Chem. 2006 Mar 3;281(9):5760-70. Epub 2005 Dec 28. PMID:16407195<ref>PMID:16407195</ref>
-	~~[[2dci]] is~~ a ~~1 chain~~ structure. ~~Full experimental information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2DCI OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Hemagglutinin\|Hemagglutinin]]		*[[Hemagglutinin\|Hemagglutinin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016407195<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
-	[[Category: Lai, A L.]]	+	</StructureSection>
-	[[Category: Tamm, L K.]]	+	[[Category: Lai, A L]]
		+	[[Category: Tamm, L K]]
	[[Category: Fusion peptide]]		[[Category: Fusion peptide]]
	[[Category: Ha]]		[[Category: Ha]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 11:05, 11 March 2013

2013-03-11T11:05:11Z

←Older revision		Revision as of 11:05, 11 March 2013
Line 1:		Line 1:
-	[[Image:2dci.png\|left\|200px]]
-
	{{STRUCTURE_2dci\| PDB=2dci \| SCENE= }}		{{STRUCTURE_2dci\| PDB=2dci \| SCENE= }}
-
	===NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5===		===NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5===
-
	{{ABSTRACT_PUBMED_16407195}}		{{ABSTRACT_PUBMED_16407195}}

OCA at 21:24, 20 October 2012

2012-10-20T21:24:07Z

←Older revision		Revision as of 21:24, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2dci]] is a 1 chain structure ~~of [[Hemagglutinin]]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA].	+	[[2dci]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA].

	==See Also==		==See Also==

OCA: Protected "2dci" [edit=sysop:move=sysop]

2012-07-27T13:08:28Z

Protected "2dci" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:08, 27 July 2012

OCA at 13:08, 27 July 2012

2012-07-27T13:08:26Z

←Older revision		Revision as of 13:08, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2dci.png\|left\|200px]]		[[Image:2dci.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2dci", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2dci\| PDB=2dci \| SCENE= }}		{{STRUCTURE_2dci\| PDB=2dci \| SCENE= }}

	===NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5===		===NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16407195}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16407195 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16407195}}		{{ABSTRACT_PUBMED_16407195}}

	==About this Structure==		==About this Structure==
-	~~2DCI~~ is a [[~~Single protein~~]] ~~structure~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA].	+	[[2dci]] is a 1 chain structure of [[Hemagglutinin]]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCI OCA].
		+
		+	==See Also==
		+	*[[Hemagglutinin\|Hemagglutinin]]

	==Reference==		==Reference==
-	~~Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity., Lai AL, Park H, White JM, Tamm LK, J Biol Chem. 2006 Mar 3;281(9):5760-70. Epub 2005 Dec 28.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16407195 16407195]~~	+	<ref group="xtra">PMID:016407195</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Lai, A L.]]		[[Category: Lai, A L.]]
	[[Category: Tamm, L K.]]		[[Category: Tamm, L K.]]
	[[Category: Fusion peptide]]		[[Category: Fusion peptide]]
	[[Category: Ha]]		[[Category: Ha]]
-		+	[[Category: Viral protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Jul 29 13:22:54 2008''~~	+