2dfl - Revision history

OCA at 08:26, 25 October 2023

2023-10-25T08:26:34Z

←Older revision		Revision as of 08:26, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2dfl' size='340' side='right'caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2dfl' size='340' side='right'caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~'saccharolobus_solfataricus' 'saccharolobus~~ solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1t4g\|1t4g]], [[1pzn\|1pzn]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">RadA ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=2287 'Saccharolobus solfataricus'])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [https://pdbe.org/2dfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [https://www.ebi.ac.uk/pdbsum/2dfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [https://pdbe.org/2dfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [https://www.ebi.ac.uk/pdbsum/2dfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~RADA_SULSO RADA_SULSO]~~] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.	+	[https://www.uniprot.org/uniprot/RADA_SACS2 RADA_SACS2] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Saccharolobus solfataricus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Chen, L T~~]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: ~~Ko, T P~~]]	+	[[Category: Chen LT]]
-	[[Category: ~~Wang, A H.J~~]]	+	[[Category: Ko TP]]
-	[[Category: Wang~~, T F~~]]	+	[[Category: Wang AHJ]]
-	[[Category: ~~Archaea]]~~	+	[[Category: Wang TF]]
-	~~[[Category: Dmc1]]~~	+
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Filament]]~~	+
-	~~[[Category: Left-handed]]~~	+
-	~~[[Category: Molecular switch]]~~	+
-	~~[[Category: Rad51]]~~	+
-	~~[[Category: Reca]]~~	+
-	~~[[Category: Recombination~~]]	+

OCA at 12:01, 3 February 2021

2021-02-03T12:01:29Z

←Older revision		Revision as of 12:01, 3 February 2021
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	==Crystal structure of left-handed RadA filament==		==Crystal structure of left-handed RadA filament==
-	<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='2dfl' size='340' side='right'caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DFL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1t4g\|1t4g]], [[1pzn\|1pzn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 'Saccharolobus solfataricus'])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 'Saccharolobus solfataricus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [~~http~~://pdbe.org/2dfl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dfl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [https://pdbe.org/2dfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [https://www.ebi.ac.uk/pdbsum/2dfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RADA_SULSO RADA_SULSO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.	+	[[https://www.uniprot.org/uniprot/RADA_SULSO RADA_SULSO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Resolvase\|Resolvase]]	+	*[[Resolvase 3D structures\|Resolvase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Saccharolobus solfataricus]]		[[Category: Saccharolobus solfataricus]]
		+	[[Category: Large Structures]]
	[[Category: Chen, L T]]		[[Category: Chen, L T]]
	[[Category: Ko, T P]]		[[Category: Ko, T P]]

OCA at 06:14, 30 May 2018

2018-05-30T06:14:32Z

←Older revision		Revision as of 06:14, 30 May 2018
Line 1:		Line 1:
		+
	==Crystal structure of left-handed RadA filament==		==Crystal structure of left-handed RadA filament==
	<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~ATCC 35091~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 'Saccharolobus solfataricus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://pdbe.org/2dfl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://pdbe.org/2dfl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfl_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfl_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dfl ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 35091~~]]	+	[[Category: Saccharolobus solfataricus]]
	[[Category: Chen, L T]]		[[Category: Chen, L T]]
	[[Category: Ko, T P]]		[[Category: Ko, T P]]

OCA at 15:04, 11 September 2015

2015-09-11T15:04:13Z

←Older revision		Revision as of 15:04, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~Sulfolobus solfataricus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://pdbe.org/2dfl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2dfl" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Atcc 35091]]
	[[Category: Chen, L T]]		[[Category: Chen, L T]]
	[[Category: Ko, T P]]		[[Category: Ko, T P]]

OCA at 18:07, 25 December 2014

2014-12-25T18:07:34Z

←Older revision		Revision as of 18:07, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RADA_SULSO RADA_SULSO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
-	[[Category: Chen, L T.]]	+	[[Category: Chen, L T]]
-	[[Category: Ko, T P.]]	+	[[Category: Ko, T P]]
-	[[Category: Wang, A H.J.]]	+	[[Category: Wang, A H.J]]
-	[[Category: Wang, T F.]]	+	[[Category: Wang, T F]]
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Dmc1]]		[[Category: Dmc1]]

OCA at 05:32, 29 September 2014

2014-09-29T05:32:26Z

←Older revision		Revision as of 05:32, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2dfl.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of left-handed RadA filament==
		+	<StructureSection load='2dfl' size='340' side='right' caption='[[2dfl]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t4g\|1t4g]], [[1pzn\|1pzn]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RadA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dfl RCSB], [http://www.ebi.ac.uk/pdbsum/2dfl PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfl_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The RecA family of proteins mediates homologous recombination, an evolutionarily conserved pathway that maintains genomic stability by protecting against DNA double strand breaks. RecA proteins are thought to facilitate DNA strand exchange reactions as closed-rings or as right-handed helical filaments. Here, we report the crystal structure of a left-handed Sulfolobus solfataricus RadA helical filament. Each protomer in this left-handed filament is linked to its neighbour via interactions of a beta-strand polymerization motif with the neighbouring ATPase domain. Immediately following the polymerization motif, we identified an evolutionarily conserved hinge region (a subunit rotation motif) in which a 360 degrees clockwise axial rotation accompanies stepwise structural transitions from a closed ring to the AMP-PNP right-handed filament, then to an overwound right-handed filament and finally to the left-handed filament. Additional structural and functional analyses of wild-type and mutant proteins confirmed that the subunit rotation motif is crucial for enzymatic functions of RecA family proteins. These observations support the hypothesis that RecA family protein filaments may function as rotary motors.

-	~~{{STRUCTURE_2dfl\| PDB=2dfl \| SCENE= }}~~	+	Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins.,Chen LT, Ko TP, Chang YC, Lin KA, Chang CS, Wang AH, Wang TF Nucleic Acids Res. 2007;35(6):1787-801. Epub 2007 Feb 28. PMID:17329376<ref>PMID:17329376</ref>

-	~~===Crystal structure~~ of ~~left-handed RadA filament===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17329376}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2dfl]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA].~~	+

	==See Also==		==See Also==
	*[[Resolvase\|Resolvase]]		*[[Resolvase\|Resolvase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017329376<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Chen, L T.]]		[[Category: Chen, L T.]]

OCA at 19:47, 20 October 2012

2012-10-20T19:47:33Z

←Older revision		Revision as of 19:47, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2dfl]] is a 1 chain structure ~~of [[Resolvase]]~~ with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA].	+	[[2dfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA].

	==See Also==		==See Also==

OCA at 08:30, 27 July 2012

2012-07-27T08:30:12Z

←Older revision		Revision as of 08:30, 27 July 2012
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	[[Image:2dfl.png\|left\|200px]]		[[Image:2dfl.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2dfl", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2dfl\| PDB=2dfl \| SCENE= }}		{{STRUCTURE_2dfl\| PDB=2dfl \| SCENE= }}

	===Crystal structure of left-handed RadA filament===		===Crystal structure of left-handed RadA filament===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17329376}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17329376 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17329376}}		{{ABSTRACT_PUBMED_17329376}}

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	==See Also==		==See Also==
-	*[[Resolvase]]	+	*[[Resolvase\|Resolvase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17329376~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017329376</ref><references group="xtra"/>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Chen, L T.]]		[[Category: Chen, L T.]]

OCA: Protected "2dfl" [edit=sysop:move=sysop]

2010-12-27T02:20:03Z

Protected "2dfl" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:20, 27 December 2010

OCA at 02:20, 27 December 2010

2010-12-27T02:20:02Z

←Older revision		Revision as of 02:20, 27 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2dfl.png\|left\|200px]]		[[Image:2dfl.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2DFL~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA].	+	[[2dfl]] is a 1 chain structure of [[Resolvase]] with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFL OCA].
		+
		+	==See Also==
		+	*[[Resolvase]]

	==Reference==		==Reference==
Line 38:		Line 40:
	[[Category: Reca]]		[[Category: Reca]]
	[[Category: Recombination]]		[[Category: Recombination]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:11:19 2009''