2ds6 - Revision history

OCA at 08:29, 25 October 2023

2023-10-25T08:29:13Z

←Older revision		Revision as of 08:29, 25 October 2023
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	<StructureSection load='2ds6' size='340' side='right'caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ds6' size='340' side='right'caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [https://pdbe.org/2ds6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ds6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ds6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [https://pdbe.org/2ds6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ds6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ds6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CLPX_ECOLI CLPX_ECOLI]] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.[HAMAP-Rule:MF_00175]	+	[https://www.uniprot.org/uniprot/CLPX_ECOLI CLPX_ECOLI] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.[HAMAP-Rule:MF_00175]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hong~~, S B~~]]	+	[[Category: Hong SB]]
-	[[Category: Lee~~, B G~~]]	+	[[Category: Lee BG]]
-	[[Category: Park~~, E Y~~]]	+	[[Category: Park EY]]
-	[[Category: Song~~, H K]]~~	+	[[Category: Song HK]]
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Substrate binding domain]]~~	+
-	~~[[Category: Zinc finger domain~~]]	+

OCA at 10:35, 8 December 2021

2021-12-08T10:35:17Z

←Older revision		Revision as of 10:35, 8 December 2021
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	<StructureSection load='2ds6' size='340' side='right'caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ds6' size='340' side='right'caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [~~http~~://pdbe.org/2ds6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ds6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ds6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [https://pdbe.org/2ds6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ds6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ds6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CLPX_ECOLI CLPX_ECOLI]] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.[HAMAP-Rule:MF_00175]	+	[[https://www.uniprot.org/uniprot/CLPX_ECOLI CLPX_ECOLI]] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.[HAMAP-Rule:MF_00175]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</div>		</div>
	<div class="pdbe-citations 2ds6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2ds6" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Clp protease 3D structures\|Clp protease 3D structures]]
-	*[[ClpX\|ClpX]]
-	*[[Zinc Fingers\|Zinc Fingers]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:43, 4 March 2020

2020-03-04T07:43:35Z

←Older revision		Revision as of 07:43, 4 March 2020
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	==Structure of the ZBD in the tetragonal crystal form==		==Structure of the ZBD in the tetragonal crystal form==
-	<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2ds6' size='340' side='right'caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Clp ~~Protease~~\|Clp ~~Protease~~]]	+	*[[Clp protease 3D structures\|Clp protease 3D structures]]
	*[[ClpX\|ClpX]]		*[[ClpX\|ClpX]]
	*[[Zinc Fingers\|Zinc Fingers]]		*[[Zinc Fingers\|Zinc Fingers]]
Line 39:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Hong, S B]]		[[Category: Hong, S B]]
	[[Category: Lee, B G]]		[[Category: Lee, B G]]

OCA at 06:26, 30 May 2018

2018-05-30T06:26:52Z

←Older revision		Revision as of 06:26, 30 May 2018
Line 1:		Line 1:
		+
	==Structure of the ZBD in the tetragonal crystal form==		==Structure of the ZBD in the tetragonal crystal form==
	<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://pdbe.org/2ds6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://pdbe.org/2ds6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ds6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/2ds6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/2ds6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 31:

	==See Also==		==See Also==
		+	*[[Clp Protease\|Clp Protease]]
	*[[ClpX\|ClpX]]		*[[ClpX\|ClpX]]
	*[[Zinc Fingers\|Zinc Fingers]]		*[[Zinc Fingers\|Zinc Fingers]]

OCA at 09:28, 8 February 2016

2016-02-08T09:28:19Z

←Older revision		Revision as of 09:28, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ds6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:12, 10 September 2015

2015-09-10T10:12:05Z

←Older revision		Revision as of 10:12, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://pdbe.org/2ds6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ds6" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Hong, S B]]		[[Category: Hong, S B]]
	[[Category: Lee, B G]]		[[Category: Lee, B G]]

OCA at 22:19, 24 December 2014

2014-12-24T22:19:03Z

←Older revision		Revision as of 22:19, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CLPX_ECOLI CLPX_ECOLI]] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP.[HAMAP-Rule:MF_00175]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Hong, S B.]]	+	[[Category: Hong, S B]]
-	[[Category: Lee, B G.]]	+	[[Category: Lee, B G]]
-	[[Category: Park, E Y.]]	+	[[Category: Park, E Y]]
-	[[Category: Song, H K.]]	+	[[Category: Song, H K]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Substrate binding domain]]		[[Category: Substrate binding domain]]
	[[Category: Zinc finger domain]]		[[Category: Zinc finger domain]]

OCA at 00:06, 30 September 2014

2014-09-30T00:06:37Z

←Older revision		Revision as of 00:06, 30 September 2014
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-	~~{{STRUCTURE_2ds6~~\| ~~PDB~~=2ds6 \| ~~SCENE~~= }}	+	==Structure of the ZBD in the tetragonal crystal form==
-	===~~Structure~~ of the ~~ZBD in~~ the ~~tetragonal crystal form~~===	+	<StructureSection load='2ds6' size='340' side='right' caption='[[2ds6]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_17258768}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DS6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ds5\|2ds5]], [[2ds7\|2ds7]], [[2ds8\|2ds8]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ds6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ds6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/2ds6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The degradation of ssrA(AANDENYALAA)-tagged proteins in the bacterial cytosol is carried out by the ClpXP protease and is markedly stimulated by the SspB adaptor protein. It has previously been reported that the amino-terminal zinc-binding domain of ClpX (ZBD) is involved in complex formation with the SspB-tail (XB: ClpX-binding motif). In an effort to better understand the recognition of SspB by ClpX and the mechanism of delivery of ssrA-tagged substrates to ClpXP, we have determined the structures of ZBD alone at 1.5, 2.0, and 2.5 A resolution in each different crystal form and also in complex with XB peptide at 1.6 A resolution. The XB peptide forms an antiparallel beta-sheet with two beta-strands of ZBD, and the structure shows a 1:1 stoichiometric complex between ZBD and XB, suggesting that there are two independent SspB-tail-binding sites in ZBD. The high-resolution ZBD:XB complex structure, in combination with biochemical analyses, can account for key determinants in the recognition of the SspB-tail by ClpX and sheds light on the mechanism of delivery of target proteins to the prokaryotic degradation machine.

-	~~==About this Structure==~~	+	Structural basis of SspB-tail recognition by the zinc binding domain of ClpX.,Park EY, Lee BG, Hong SB, Kim HW, Jeon H, Song HK J Mol Biol. 2007 Mar 23;367(2):514-26. Epub 2007 Jan 9. PMID:17258768<ref>PMID:17258768</ref>
-	~~[[2ds6]] is a~~ 2 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2DS6 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[ClpX\|ClpX]]		*[[ClpX\|ClpX]]
	*[[Zinc Fingers\|Zinc Fingers]]		*[[Zinc Fingers\|Zinc Fingers]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017258768<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Hong, S B.]]		[[Category: Hong, S B.]]

OCA at 09:18, 11 March 2013

2013-03-11T09:18:39Z

←Older revision		Revision as of 09:18, 11 March 2013
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-	[[Image:2ds6.png\|left\|200px]]
-
	{{STRUCTURE_2ds6\| PDB=2ds6 \| SCENE= }}		{{STRUCTURE_2ds6\| PDB=2ds6 \| SCENE= }}
-
	===Structure of the ZBD in the tetragonal crystal form===		===Structure of the ZBD in the tetragonal crystal form===
-
	{{ABSTRACT_PUBMED_17258768}}		{{ABSTRACT_PUBMED_17258768}}

OCA at 09:42, 20 October 2012

2012-10-20T09:42:19Z

←Older revision		Revision as of 09:42, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2ds6]] is a 2 chain structure ~~of [[ClpX]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA].	+	[[2ds6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DS6 OCA].

	==See Also==		==See Also==