2e1m - Revision history

OCA at 08:33, 25 October 2023

2023-10-25T08:33:26Z

←Older revision		Revision as of 08:33, 25 October 2023
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	<StructureSection load='2e1m' size='340' side='right'caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2e1m' size='340' side='right'caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E1M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._X-119-6 Streptomyces sp. X-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FAD:FLAVIN~~-~~ADENINE+DINUCLEOTIDE'>FAD</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https:~~/~~/en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase]~~, ~~with EC number [https~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [https://pdbe.org/2e1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [https://www.ebi.ac.uk/pdbsum/2e1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1m ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [https://pdbe.org/2e1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [https://www.ebi.ac.uk/pdbsum/2e1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1m ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8L3C7_9ACTN Q8L3C7_9ACTN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: L-glutamate oxidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Streptomyces sp. x-119-6]]	+	[[Category: Streptomyces sp. X-119-6]]
-	[[Category: Arima, J]]	+	[[Category: Arima J]]
-	[[Category: Inagaki, K]]	+	[[Category: Inagaki K]]
-	[[Category: Kashima, A]]	+	[[Category: Kashima A]]
-	[[Category: Kusakabe, H]]	+	[[Category: Kusakabe H]]
-	[[Category: Mizuno, H]]	+	[[Category: Mizuno H]]
-	[[Category: Sakaguchi, C]]	+	[[Category: Sakaguchi C]]
-	[[Category: Sasaki, C]]	+	[[Category: Sasaki C]]
-	[[Category: Sugio, S]]	+	[[Category: Sugio S]]
-	[[Category: Tamura, T]]	+	[[Category: Tamura T]]
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: L-amino acid oxidase]]~~	+
-	~~[[Category: L-gox]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 17:19, 15 December 2021

2021-12-15T17:19:22Z

←Older revision		Revision as of 17:19, 15 December 2021
Line 3:		Line 3:
	<StructureSection load='2e1m' size='340' side='right'caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2e1m' size='340' side='right'caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2E1M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [~~http~~://pdbe.org/2e1m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2e1m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1m ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [https://pdbe.org/2e1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [https://www.ebi.ac.uk/pdbsum/2e1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1m ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:25, 11 March 2020

2020-03-11T08:25:24Z

←Older revision		Revision as of 08:25, 11 March 2020
Line 1:		Line 1:

	==Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6==		==Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6==
-	<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='2e1m' size='340' side='right'caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: L-glutamate oxidase]]		[[Category: L-glutamate oxidase]]
		+	[[Category: Large Structures]]
	[[Category: Streptomyces sp. x-119-6]]		[[Category: Streptomyces sp. x-119-6]]
	[[Category: Arima, J]]		[[Category: Arima, J]]

OCA at 06:53, 6 June 2018

2018-06-06T06:53:48Z

←Older revision		Revision as of 06:53, 6 June 2018
Line 1:		Line 1:
		+
	==Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6==		==Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6==
	<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://pdbe.org/2e1m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://pdbe.org/2e1m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1m ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e1/2e1m_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e1/2e1m_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:54, 9 February 2016

2016-02-09T02:54:15Z

←Older revision		Revision as of 02:54, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e1m ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:54, 10 September 2015

2015-09-10T17:54:53Z

←Older revision		Revision as of 17:54, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._x-119-6 Streptomyces sp. x-119-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://pdbe.org/2e1m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2e1m" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: L-glutamate oxidase]]		[[Category: L-glutamate oxidase]]
-	[[Category: Streptomyces sp]]	+	[[Category: Streptomyces sp. x-119-6]]
	[[Category: Arima, J]]		[[Category: Arima, J]]
	[[Category: Inagaki, K]]		[[Category: Inagaki, K]]

OCA at 16:41, 15 January 2015

2015-01-15T16:41:15Z

←Older revision		Revision as of 16:41, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: L-glutamate oxidase]]		[[Category: L-glutamate oxidase]]
-	[[Category: Streptomyces sp.]]	+	[[Category: Streptomyces sp]]
-	[[Category: Arima, J.]]	+	[[Category: Arima, J]]
-	[[Category: Inagaki, K.]]	+	[[Category: Inagaki, K]]
-	[[Category: Kashima, A.]]	+	[[Category: Kashima, A]]
-	[[Category: Kusakabe, H.]]	+	[[Category: Kusakabe, H]]
-	[[Category: Mizuno, H.]]	+	[[Category: Mizuno, H]]
-	[[Category: Sakaguchi, C.]]	+	[[Category: Sakaguchi, C]]
-	[[Category: Sasaki, C.]]	+	[[Category: Sasaki, C]]
-	[[Category: Sugio, S.]]	+	[[Category: Sugio, S]]
-	[[Category: Tamura, T.]]	+	[[Category: Tamura, T]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
	[[Category: L-amino acid oxidase]]		[[Category: L-amino acid oxidase]]
-	[[Category: L-glutamate oxidase]]
	[[Category: L-gox]]		[[Category: L-gox]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 01:54, 30 September 2014

2014-09-30T01:54:44Z

←Older revision		Revision as of 01:54, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2e1m.~~png\|left~~\|200px]]	+	==Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6==
		+	<StructureSection load='2e1m' size='340' side='right' caption='[[2e1m]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E1M FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-glutamate_oxidase L-glutamate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.11 1.4.3.11] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e1m RCSB], [http://www.ebi.ac.uk/pdbsum/2e1m PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e1/2e1m_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	L-Glutamate oxidase (LGOX) from Streptomyces sp. X-119-6, which catalyzes the oxidative deamination of L-glutamate, has attracted increasing attention as a component of amperometric L-glutamate sensors used in the food industry and clinical biochemistry. The precursor of LGOX, which has a homodimeric structure, is less active than the mature enzyme with an alpha(2)beta(2)V(2) structure; enzymatic proteolysis of the precursor forms the stable mature enzyme. We solved the crystal structure of mature LGOX using molecular replacement with a structurally homologous model of L-amino acid oxidase (LAAO) from snake venom: LGOX has a deeply buried active site and two entrances from the surface of the protein into the active site. Comparison of the LGOX structure with that of LAAO revealed that LGOX has three regions that are absent from the LAAO structure, one of which is involved in the formation of the entrance. Furthermore, the arrangement of the residues composing the active site differs between LGOX and LAAO, and the active site of LGOX is narrower than that of LAAO. Results of the comparative analyses described herein raise the possibility that such a unique structure of LGOX is associated with its substrate specificity.

-	~~{{STRUCTURE_2e1m\| PDB=2e1m \| SCENE= }}~~	+	Structural characterization of L-glutamate oxidase from Streptomyces sp. X-119-6.,Arima J, Sasaki C, Sakaguchi C, Mizuno H, Tamura T, Kashima A, Kusakabe H, Sugio S, Inagaki K FEBS J. 2009 Jul;276(14):3894-903. Epub 2009 Jun 15. PMID:19531050<ref>PMID:19531050</ref>

-	~~===Crystal Structure~~ of ~~L-Glutamate Oxidase from Streptomyces sp~~. ~~X-119-6===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19531050}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2e1m]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019531050<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: L-glutamate oxidase]]		[[Category: L-glutamate oxidase]]
	[[Category: Streptomyces sp.]]		[[Category: Streptomyces sp.]]

OCA: Protected "2e1m" [edit=sysop:move=sysop]

2013-01-06T11:08:15Z

Protected "2e1m" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:08, 6 January 2013

OCA at 11:08, 6 January 2013

2013-01-06T11:08:11Z

←Older revision		Revision as of 11:08, 6 January 2013
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-	{{Seed}}
	[[Image:2e1m.png\|left\|200px]]		[[Image:2e1m.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2e1m", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2e1m\| PDB=2e1m \| SCENE= }}		{{STRUCTURE_2e1m\| PDB=2e1m \| SCENE= }}

	===Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6===		===Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19531050}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19531050 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19531050}}		{{ABSTRACT_PUBMED_19531050}}

	==About this Structure==		==About this Structure==
-	~~2E1M~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/~~Bacteria Bacteria~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA].	+	[[2e1m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1M OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19531050~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019531050</ref><references group="xtra"/>
-	~~[[Category: Bacteria]]~~	+
	[[Category: L-glutamate oxidase]]		[[Category: L-glutamate oxidase]]
		+	[[Category: Streptomyces sp.]]
	[[Category: Arima, J.]]		[[Category: Arima, J.]]
	[[Category: Inagaki, K.]]		[[Category: Inagaki, K.]]
Line 35:		Line 23:
	[[Category: Sugio, S.]]		[[Category: Sugio, S.]]
	[[Category: Tamura, T.]]		[[Category: Tamura, T.]]
-	[[Category: 3d-structure]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
Line 42:		Line 29:
	[[Category: L-gox]]		[[Category: L-gox]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Aug 4 16:47:06 2009''