2e7z - Revision history

OCA at 09:50, 5 May 2021

2021-05-05T09:50:07Z

←Older revision		Revision as of 09:50, 5 May 2021
Line 3:		Line 3:
	<StructureSection load='2e7z' size='340' side='right'caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>		<StructureSection load='2e7z' size='340' side='right'caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Dsm_3246 Dsm 3246~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [~~http~~://pdbe.org/2e7z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2e7z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7z ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [https://pdbe.org/2e7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [https://www.ebi.ac.uk/pdbsum/2e7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AHY_PELAE AHY_PELAE]] Catalyzes the hydration of acetylene to form acetaldehyde. Ethylene cannot act as a substrate.<ref>PMID:7592321</ref>	+	[[https://www.uniprot.org/uniprot/AHY_PELAE AHY_PELAE]] Catalyzes the hydration of acetylene to form acetaldehyde. Ethylene cannot act as a substrate.<ref>PMID:7592321</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
-	[[Category: Dsm 3246]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Pelobacter acetylenicus]]
	[[Category: Einsle, O]]		[[Category: Einsle, O]]
	[[Category: Kroneck, P M.H]]		[[Category: Kroneck, P M.H]]

OCA at 09:33, 24 July 2019

2019-07-24T09:33:28Z

←Older revision		Revision as of 09:33, 24 July 2019
Line 1:		Line 1:

	==Acetylene Hydratase from Pelobacter acetylenicus==		==Acetylene Hydratase from Pelobacter acetylenicus==
-	<StructureSection load='2e7z' size='340' side='right' caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>	+	<StructureSection load='2e7z' size='340' side='right'caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_3246 Dsm 3246]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_3246 Dsm 3246]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7z_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7z_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
	[[Category: Dsm 3246]]		[[Category: Dsm 3246]]
		+	[[Category: Large Structures]]
	[[Category: Einsle, O]]		[[Category: Einsle, O]]
	[[Category: Kroneck, P M.H]]		[[Category: Kroneck, P M.H]]

OCA at 14:23, 12 October 2017

2017-10-12T14:23:36Z

←Older revision		Revision as of 14:23, 12 October 2017
Line 1:		Line 1:
		+
	==Acetylene Hydratase from Pelobacter acetylenicus==		==Acetylene Hydratase from Pelobacter acetylenicus==
	<StructureSection load='2e7z' size='340' side='right' caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>		<StructureSection load='2e7z' size='340' side='right' caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pelobacter_acetylenicus Pelobacter acetylenicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_3246 Dsm 3246]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://pdbe.org/2e7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://pdbe.org/2e7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
-	[[Category: ~~Pelobacter acetylenicus~~]]	+	[[Category: Dsm 3246]]
	[[Category: Einsle, O]]		[[Category: Einsle, O]]
	[[Category: Kroneck, P M.H]]		[[Category: Kroneck, P M.H]]

OCA at 03:25, 9 February 2016

2016-02-09T03:25:41Z

←Older revision		Revision as of 03:25, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7z ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:09, 10 September 2015

2015-09-10T18:09:28Z

←Older revision		Revision as of 18:09, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://pdbe.org/2e7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AHY_PELAE AHY_PELAE]] Catalyzes the hydration of acetylene to form acetaldehyde. Ethylene cannot act as a substrate.<ref>PMID:7592321</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 25:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2e7z" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:08, 15 January 2015

2015-01-15T17:08:20Z

←Older revision		Revision as of 17:08, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
	[[Category: Pelobacter acetylenicus]]		[[Category: Pelobacter acetylenicus]]
-	[[Category: Einsle, O.]]	+	[[Category: Einsle, O]]
-	[[Category: Kroneck, P M.H.]]	+	[[Category: Kroneck, P M.H]]
-	[[Category: Messerschmidt, A.]]	+	[[Category: Messerschmidt, A]]
-	[[Category: Seiffert, G B.]]	+	[[Category: Seiffert, G B]]
	[[Category: Dmso reductase family]]		[[Category: Dmso reductase family]]
	[[Category: Iron-sulfur-cluster]]		[[Category: Iron-sulfur-cluster]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Tungstoprotein]]		[[Category: Tungstoprotein]]

OCA at 02:09, 30 September 2014

2014-09-30T02:09:50Z

←Older revision		Revision as of 02:09, 30 September 2014
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-	[[~~Image~~:2e7z.~~png\|left~~\|200px]]	+	==Acetylene Hydratase from Pelobacter acetylenicus==
		+	<StructureSection load='2e7z' size='340' side='right' caption='[[2e7z]], [[Resolution\|resolution]] 1.26Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7Z FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=W:TUNGSTEN+ION'>W</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylenecarboxylate_hydratase Acetylenecarboxylate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.27 4.2.1.27] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e7z RCSB], [http://www.ebi.ac.uk/pdbsum/2e7z PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7z_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The tungsten-iron-sulfur enzyme acetylene hydratase stands out from its class because it catalyzes a nonredox reaction, the hydration of acetylene to acetaldehyde. Sequence comparisons group the protein into the dimethyl sulfoxide reductase family, and it contains a bis-molybdopterin guanine dinucleotide-ligated tungsten atom and a cubane-type [4Fe:4S] cluster. The crystal structure of acetylene hydratase at 1.26 A now shows that the tungsten center binds a water molecule that is activated by an adjacent aspartate residue, enabling it to attack acetylene bound in a distinct, hydrophobic pocket. This mechanism requires a strong shift of pK(a) of the aspartate, caused by a nearby low-potential [4Fe:4S] cluster. To access this previously unrecognized W-Asp active site, the protein evolved a new substrate channel distant from where it is found in other molybdenum and tungsten enzymes.

-	~~{{STRUCTURE_2e7z\| PDB=2e7z \| SCENE= }}~~	+	Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase.,Seiffert GB, Ullmann GM, Messerschmidt A, Schink B, Kroneck PM, Einsle O Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3073-7. PMID:17360611<ref>PMID:17360611</ref>

-	~~===Acetylene Hydratase from Pelobacter acetylenicus===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17360611}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2e7z]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017360611<~~/~~ref~~><~~ref group="xtra">PMID:016511024</ref><references group="xtra"~~/>	+
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
	[[Category: Pelobacter acetylenicus]]		[[Category: Pelobacter acetylenicus]]

OCA at 12:29, 23 January 2013

2013-01-23T12:29:46Z

←Older revision		Revision as of 12:29, 23 January 2013
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	[[Image:2e7z.png\|left\|200px]]		[[Image:2e7z.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2e7z", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2e7z\| PDB=2e7z \| SCENE= }}		{{STRUCTURE_2e7z\| PDB=2e7z \| SCENE= }}

	===Acetylene Hydratase from Pelobacter acetylenicus===		===Acetylene Hydratase from Pelobacter acetylenicus===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17360611}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17360611 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17360611}}		{{ABSTRACT_PUBMED_17360611}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17360611~~</ref><ref group="xtra">PMID:~~16511024~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017360611</ref><ref group="xtra">PMID:016511024</ref><references group="xtra"/>
	[[Category: Acetylenecarboxylate hydratase]]		[[Category: Acetylenecarboxylate hydratase]]
	[[Category: Pelobacter acetylenicus]]		[[Category: Pelobacter acetylenicus]]

OCA: Protected "2e7z" [edit=sysop:move=sysop]

2011-03-14T22:46:56Z

Protected "2e7z" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:46, 14 March 2011

OCA at 22:46, 14 March 2011

2011-03-14T22:46:55Z

←Older revision		Revision as of 22:46, 14 March 2011
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-	{{Seed}}
	[[Image:2e7z.png\|left\|200px]]		[[Image:2e7z.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2E7Z~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA].	+	[[2e7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pelobacter_acetylenicus Pelobacter acetylenicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Z OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:17360611</ref><ref group="xtra">PMID:16511024</ref><references group="xtra"/>		<ref group="xtra">PMID:17360611</ref><ref group="xtra">PMID:16511024</ref><references group="xtra"/>
-	[[Category: ~~Deleted entry~~]]	+	[[Category: Acetylenecarboxylate hydratase]]
	[[Category: Pelobacter acetylenicus]]		[[Category: Pelobacter acetylenicus]]
	[[Category: Einsle, O.]]		[[Category: Einsle, O.]]
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	[[Category: Dmso reductase family]]		[[Category: Dmso reductase family]]
	[[Category: Iron-sulfur-cluster]]		[[Category: Iron-sulfur-cluster]]
		+	[[Category: Lyase]]
	[[Category: Tungstoprotein]]		[[Category: Tungstoprotein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:05:25 2009''