2efo - Revision history

OCA at 08:39, 25 October 2023

2023-10-25T08:39:24Z

←Older revision		Revision as of 08:39, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2efo' size='340' side='right'caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2efo' size='340' side='right'caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Sulto Sulto~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">ST1022 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [https://pdbe.org/2efo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [https://www.ebi.ac.uk/pdbsum/2efo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efo ProSAT], [https://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [https://pdbe.org/2efo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [https://www.ebi.ac.uk/pdbsum/2efo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efo ProSAT], [https://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/F9VNT4_SULTO F9VNT4_SULTO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sulto~~]]	+	[[Category: Sulfurisphaera tokodaii str. 7]]
-	[[Category: Karthe, P]]	+	[[Category: Karthe P]]
-	[[Category: Kumarevel~~, T S~~]]	+	[[Category: Kumarevel TS]]
-	[[Category: Nakano, N]]	+	[[Category: Nakano N]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Shinkai A]]
-	[[Category: Shinkai, A]]	+	[[Category: Yokoyama S]]
-	[[Category: Yokoyama, S]]	+
-	~~[[Category: Lrp/asnc family gln binding]]~~	+
-	~~[[Category: National project on protein structural and functional analyse]]~~	+
-	~~[[Category: Nppsfa]]~~	+
-	~~[[Category: Rsgi]]~~	+
-	~~[[Category: St1022]]~~	+
-	~~[[Category: Transcription regulator]]~~	+
-	~~[[Category: Transcriptional regulator~~]]	+

OCA at 12:04, 10 February 2021

2021-02-10T12:04:45Z

←Older revision		Revision as of 12:04, 10 February 2021
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	==Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7==		==Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7==
-	<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='2efo' size='340' side='right'caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sulto Sulto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2EFO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulto Sulto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [~~http~~://pdbe.org/2efo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2efo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2efo ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [https://pdbe.org/2efo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [https://www.ebi.ac.uk/pdbsum/2efo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efo ProSAT], [https://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/2efo_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/2efo_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Sulto]]		[[Category: Sulto]]
	[[Category: Karthe, P]]		[[Category: Karthe, P]]

OCA at 10:19, 12 October 2017

2017-10-12T10:19:55Z

←Older revision		Revision as of 10:19, 12 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7==		==Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7==
	<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://pdbe.org/2efo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://pdbe.org/2efo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2efo ProSAT], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2efo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:23, 12 September 2015

2015-09-12T00:23:48Z

←Older revision		Revision as of 00:23, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulto Sulto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 ~~Sulfolobus tokodaii str. 7~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 SULTO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://pdbe.org/2efo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2efo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sulfolobus tokodaii str. 7~~]]	+	[[Category: Sulto]]
	[[Category: Karthe, P]]		[[Category: Karthe, P]]
	[[Category: Kumarevel, T S]]		[[Category: Kumarevel, T S]]

OCA at 17:29, 15 January 2015

2015-01-15T17:29:06Z

←Older revision		Revision as of 17:29, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 Sulfolobus tokodaii str. 7])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 Sulfolobus tokodaii str. 7])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Sulfolobus tokodaii str. 7]]		[[Category: Sulfolobus tokodaii str. 7]]
-	[[Category: Karthe, P.]]	+	[[Category: Karthe, P]]
-	[[Category: Kumarevel, T S.]]	+	[[Category: Kumarevel, T S]]
-	[[Category: Nakano, N.]]	+	[[Category: Nakano, N]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Shinkai, A.]]	+	[[Category: Shinkai, A]]
-	[[Category: Yokoyama, S.]]	+	[[Category: Yokoyama, S]]
	[[Category: Lrp/asnc family gln binding]]		[[Category: Lrp/asnc family gln binding]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
-	[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: St1022]]		[[Category: St1022]]
-	[[Category: Structural genomic]]
	[[Category: Transcription regulator]]		[[Category: Transcription regulator]]
	[[Category: Transcriptional regulator]]		[[Category: Transcriptional regulator]]

OCA at 00:42, 30 September 2014

2014-09-30T00:42:55Z

←Older revision		Revision as of 00:42, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2efo.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7==
		+	<StructureSection load='2efo' size='340' side='right' caption='[[2efo]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EFO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e7w\|2e7w]], [[2e7x\|2e7x]], [[2efn\|2efn]], [[2efp\|2efp]], [[2efq\|2efq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ST1022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273063 Sulfolobus tokodaii str. 7])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2efo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2efo RCSB], [http://www.ebi.ac.uk/pdbsum/2efo PDBsum], [http://www.topsan.org/Proteins/RSGI/2efo TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/2efo_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Genome analyses have revealed that members of the Lrp/AsnC family of transcriptional regulators are widely distributed among prokaryotes, including both bacteria and archaea. These regulatory proteins are involved in cellular metabolism in both global and specific manners, depending on the availability of the exogenous amino acid effectors. Here we report the first crystal structure of glutamine receptor protein (Grp) from Sulfolobus tokodaii strain 7, in the ligand-free and glutamine-bound (Grp-Gln) forms. Although the overall structures of both molecules are similar, a significant conformational change was observed at the ligand [L-glutamine (Gln)] binding site in the effector domain, which may be essential for further stabilization of the octameric structure, and in turn for facilitating DNA binding. In addition, we predicted promoter for the grp gene, and these analyses suggested the importance of cooperative binding to the protein. To gain insights into the ligand-induced conformational changes, we mutated all of the ligand-binding residues in Grp, and revealed the importance of Gln binding by biochemical and structural analyses. Further structural analyses showed that Y77 is crucial for ligand binding, and that the residues T132 and T134, which are highly conserved among the Lrp family of proteins, fluctuates between the active and inactive conformations, thus affecting protein oligomerization for DNA binding.

-	~~{{STRUCTURE_2efo\| PDB=2efo \| SCENE= }}~~	+	Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding.,Kumarevel T, Nakano N, Ponnuraj K, Gopinath SC, Sakamoto K, Shinkai A, Kumar PK, Yokoyama S Nucleic Acids Res. 2008 Aug;36(14):4808-20. Epub 2008 Jul 24. PMID:18653535<ref>PMID:18653535</ref>

-	~~===Crystal structure~~ of ~~Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18653535}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2efo]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_tokodaii_str~~.~~_7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018653535<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Sulfolobus tokodaii str. 7]]		[[Category: Sulfolobus tokodaii str. 7]]
	[[Category: Karthe, P.]]		[[Category: Karthe, P.]]

OCA: Protected "2efo" [edit=sysop:move=sysop]

2013-01-06T10:03:55Z

Protected "2efo" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:03, 6 January 2013

OCA at 10:03, 6 January 2013

2013-01-06T10:03:53Z

←Older revision		Revision as of 10:03, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2efo.png\|left\|200px]]		[[Image:2efo.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2efo", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2efo\| PDB=2efo \| SCENE= }}		{{STRUCTURE_2efo\| PDB=2efo \| SCENE= }}

	===Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7===		===Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18653535}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18653535 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18653535}}		{{ABSTRACT_PUBMED_18653535}}

	==About this Structure==		==About this Structure==
-	~~2EFO~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].	+	[[2efo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18653535~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018653535</ref><references group="xtra"/>
	[[Category: Sulfolobus tokodaii str. 7]]		[[Category: Sulfolobus tokodaii str. 7]]
	[[Category: Karthe, P.]]		[[Category: Karthe, P.]]
Line 40:		Line 28:
	[[Category: Transcription regulator]]		[[Category: Transcription regulator]]
	[[Category: Transcriptional regulator]]		[[Category: Transcriptional regulator]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:17 2009''

OCA at 08:25, 22 March 2009

2009-03-22T08:25:20Z

←Older revision		Revision as of 08:25, 22 March 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2EFO is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].	+	2EFO is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].

	==Reference==		==Reference==
-	Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding., Kumarevel T, Nakano N, Ponnuraj K, Gopinath SC, Sakamoto K, Shinkai A, Kumar PK, Yokoyama S, Nucleic Acids Res. 2008 Aug;36(14):4808-20. Epub 2008 Jul 24. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18653535 18653535]~~	+	<ref group="xtra">PMID:18653535</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Sulfolobus tokodaii str. 7]]		[[Category: Sulfolobus tokodaii str. 7]]
-	[[Category: ~~Pdbx_ordinal=~~, ~~<PDBx~~:~~audit_author~~.]]	+	[[Category: Karthe, P.]]
		+	[[Category: Kumarevel, T S.]]
		+	[[Category: Nakano, N.]]
		+	[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
		+	[[Category: Shinkai, A.]]
		+	[[Category: Yokoyama, S.]]
	[[Category: Lrp/asnc family gln binding]]		[[Category: Lrp/asnc family gln binding]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
Line 37:		Line 41:
	[[Category: Transcriptional regulator]]		[[Category: Transcriptional regulator]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Mar ~~18 20~~:19:14 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:17 2009''

OCA at 18:19, 18 March 2009

2009-03-18T18:19:15Z

←Older revision		Revision as of 18:19, 18 March 2009
Line 12:		Line 12:
	===Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7===		===Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18653535}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18653535 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18653535}}

	==About this Structure==		==About this Structure==
-	2EFO is a ~~1 chain~~ structure of sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_tokodaii~~ Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].	+	2EFO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii_str._7 Sulfolobus tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFO OCA].
-	~~[[Category:~~ Sulfolobus tokodaii]]	+
-	~~[[Category~~: ~~Karthe, P~~.]]	+	==Reference==
-	~~[[Category: Kumarevel~~, T S.]]	+	Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding., Kumarevel T, Nakano N, Ponnuraj K, Gopinath SC, Sakamoto K, Shinkai A, Kumar PK, Yokoyama S, Nucleic Acids Res. 2008 Aug;36(14):4808-20. Epub 2008 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18653535 18653535]
-	[[Category: ~~Nakano, N.~~]]	+	[[Category: Single protein]]
-	[[Category: ~~RSGI, RIKEN Structural Genomics/Proteomics Initiative~~.]]	+	[[Category: Sulfolobus tokodaii str. 7]]
-	[[Category: ~~Shinkai~~, A.]]	+	[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
-	[[Category: ~~Yokoyama, S.~~]]	+	[[Category: Lrp/asnc family gln binding]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
Line 29:		Line 35:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Transcription regulator]]		[[Category: Transcription regulator]]
-	[[Category: Transcriptional regulator~~,lrp/asnc family gln binding~~]]	+	[[Category: Transcriptional regulator]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Nov 16 15:52~~:19 ~~2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 18 20:19:14 2009''