2eia - Revision history

OCA at 12:08, 10 February 2021

2021-02-10T12:08:33Z

←Older revision		Revision as of 12:08, 10 February 2021
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	==X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26==		==X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26==
-	<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='2eia' size='340' side='right'caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Eiav Eiav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2EIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Eiav Eiav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EIA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [~~http~~://pdbe.org/2eia PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2eia PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2eia ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [https://pdbe.org/2eia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [https://www.ebi.ac.uk/pdbsum/2eia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eia ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GAG_EIAVY GAG_EIAVY]] Matrix protein p15 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane (By similarity). Capsid protein p26 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p11 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). p9 plays a role in budding of the assembled particle by interacting with PDCD6IP/AIP1 (By similarity).	+	[[https://www.uniprot.org/uniprot/GAG_EIAVY GAG_EIAVY]] Matrix protein p15 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane (By similarity). Capsid protein p26 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p11 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). p9 plays a role in budding of the assembled particle by interacting with PDCD6IP/AIP1 (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Eiav]]		[[Category: Eiav]]
		+	[[Category: Large Structures]]
	[[Category: Jin, L]]		[[Category: Jin, L]]
	[[Category: Jin, Z]]		[[Category: Jin, Z]]

OCA at 06:35, 6 June 2018

2018-06-06T06:35:10Z

←Older revision		Revision as of 06:35, 6 June 2018
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		+
	==X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26==		==X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26==
	<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Eiav Eiav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Eiav Eiav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://pdbe.org/2eia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://pdbe.org/2eia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eia ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2eia_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2eia_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 00:12, 8 February 2016

2016-02-08T00:12:25Z

←Older revision		Revision as of 00:12, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eia ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:07, 10 September 2015

2015-09-10T06:07:06Z

←Older revision		Revision as of 06:07, 10 September 2015
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	<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Equine_infectious_anemia_virus Equine infectious anemia virus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Eiav Eiav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 ~~Equine infectious anemia virus~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 EIAV])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://pdbe.org/2eia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2eia" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Equine infectious anemia virus~~]]	+	[[Category: Eiav]]
	[[Category: Jin, L]]		[[Category: Jin, L]]
	[[Category: Jin, Z]]		[[Category: Jin, Z]]

OCA at 19:10, 24 December 2014

2014-12-24T19:10:46Z

←Older revision		Revision as of 19:10, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 Equine infectious anemia virus])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 Equine infectious anemia virus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GAG_EIAVY GAG_EIAVY]] Matrix protein p15 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane (By similarity). Capsid protein p26 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p11 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). p9 plays a role in budding of the assembled particle by interacting with PDCD6IP/AIP1 (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Equine infectious anemia virus]]		[[Category: Equine infectious anemia virus]]
-	[[Category: Jin, L.]]	+	[[Category: Jin, L]]
-	[[Category: Jin, Z.]]	+	[[Category: Jin, Z]]
-	[[Category: Lawson, C L.]]	+	[[Category: Lawson, C L]]
-	[[Category: Peterson, D L.]]	+	[[Category: Peterson, D L]]
	[[Category: Hiv]]		[[Category: Hiv]]
	[[Category: Lentivirus]]		[[Category: Lentivirus]]
	[[Category: Viral capsid eiav]]		[[Category: Viral capsid eiav]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 03:53, 29 September 2014

2014-09-29T03:53:35Z

←Older revision		Revision as of 03:53, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2eia.~~png\|left~~\|200px]]	+	==X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26==
		+	<StructureSection load='2eia' size='340' side='right' caption='[[2eia]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EIA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 Equine infectious anemia virus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2eia RCSB], [http://www.ebi.ac.uk/pdbsum/2eia PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2eia_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two crystal forms of recombinant p26 capsid protein (CA) from the equine infectious anemia virus (EIAV) have in common an antiparallel four-helix bundle dimer interface between N-terminal domains (NTDs). The dimer interface provides a lenient scaffold to accommodate the wide sequence variation in these helices within lentivirus CA. Pairs of dimers weakly associate to form exact or approximate D2 symmetry tetramers. In one of the two crystal forms, the tetramers are linked via dimerization of C-terminal domains (CTDs). We propose that the observed NTD and CTD homodimer interactions are involved in the assembly of the lentivirus capsid. The NTD homodimer shape readily suggests a model for the mature capsid core, based on hexagonal packing with dimensions and surface topology resembling described EIAV capsid cores. Combining available data for human immunodeficiency virus and EIAV CA, we also propose an assembly pathway for maturation of the lentivirus capsid core following proteolytic cleavage of the gag polyprotein precursor.

-	~~{{STRUCTURE_2eia\| PDB=2eia \| SCENE= }}~~	+	Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26.,Jin Z, Jin L, Peterson DL, Lawson CL J Mol Biol. 1999 Feb 12;286(1):83-93. PMID:9931251<ref>PMID:9931251</ref>

-	~~===X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9931251}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2eia]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA].~~	+

	==See Also==		==See Also==
	*[[Virus coat protein\|Virus coat protein]]		*[[Virus coat protein\|Virus coat protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:009931251<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Equine infectious anemia virus]]		[[Category: Equine infectious anemia virus]]
	[[Category: Jin, L.]]		[[Category: Jin, L.]]

OCA: Protected "2eia" [edit=sysop:move=sysop]

2012-10-20T08:15:44Z

Protected "2eia" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:15, 20 October 2012

OCA at 08:15, 20 October 2012

2012-10-20T08:15:41Z

←Older revision		Revision as of 08:15, 20 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2eia.png\|left\|200px]]		[[Image:2eia.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2eia", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2eia\| PDB=2eia \| SCENE= }}		{{STRUCTURE_2eia\| PDB=2eia \| SCENE= }}

	===X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26===		===X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_9931251}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 9931251 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_9931251}}		{{ABSTRACT_PUBMED_9931251}}

	==About this Structure==		==About this Structure==
-	~~2EIA~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA].	+	[[2eia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA].
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~9931251~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:009931251</ref><references group="xtra"/>
	[[Category: Equine infectious anemia virus]]		[[Category: Equine infectious anemia virus]]
	[[Category: Jin, L.]]		[[Category: Jin, L.]]
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	[[Category: Lawson, C L.]]		[[Category: Lawson, C L.]]
	[[Category: Peterson, D L.]]		[[Category: Peterson, D L.]]
-	[[Category: Crystal structure]]
	[[Category: Hiv]]		[[Category: Hiv]]
	[[Category: Lentivirus]]		[[Category: Lentivirus]]
	[[Category: Viral capsid eiav]]		[[Category: Viral capsid eiav]]
-		+	[[Category: Viral protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 17:24:54 2009''~~	+

OCA at 15:24, 16 February 2009

2009-02-16T15:24:55Z

←Older revision		Revision as of 15:24, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2EIA is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA].	+	2EIA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIA OCA].

	==Reference==		==Reference==
-	~~Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26., Jin Z, Jin L, Peterson DL, Lawson CL, J Mol Biol. 1999 Feb 12;286(1):83-93.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/9931251 9931251]~~	+	<ref group="xtra">PMID:9931251</ref><references group="xtra"/>
	[[Category: Equine infectious anemia virus]]		[[Category: Equine infectious anemia virus]]
-	[[Category: Single protein]]
	[[Category: Jin, L.]]		[[Category: Jin, L.]]
	[[Category: Jin, Z.]]		[[Category: Jin, Z.]]
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	[[Category: Viral capsid eiav]]		[[Category: Viral capsid eiav]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 20~~:48:~~52 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:24:54 2009''

OCA at 17:48, 27 July 2008

2008-07-27T17:48:56Z

←Older revision		Revision as of 17:48, 27 July 2008
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-	[[Image:2eia.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2eia.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2eia\| PDB=2eia \| SCENE= }}		{{STRUCTURE_2eia\| PDB=2eia \| SCENE= }}

-	~~'''~~X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26~~'''~~	+	===X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26===


-	~~==Overview==~~	+	<!--
-	~~Two crystal forms of recombinant p26 capsid protein (CA) from the equine infectious anemia virus (EIAV) have in common an antiparallel four~~-~~helix bundle dimer interface between N~~-~~terminal domains (NTDs).~~ The ~~dimer interface provides a lenient scaffold to accommodate~~ the ~~wide sequence variation in these helices within lentivirus CA. Pairs of dimers weakly associate~~ to ~~form exact or approximate D2 symmetry tetramers. In one of~~ the ~~two crystal forms, the tetramers are linked via dimerization of C-terminal domains~~ (~~CTDs)~~. ~~We propose that the observed NTD and CTD homodimer interactions are involved in the assembly of the lentivirus capsid~~. The NTD homodimer shape readily suggests a model for the mature capsid core, based on hexagonal packing with dimensions and surface topology resembling described EIAV capsid cores. Combining available data for human immunodeficiency virus and EIAV CA, ~~we also propose an assembly pathway for maturation of~~ the ~~lentivirus capsid core following proteolytic cleavage of the gag polyprotein precursor~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_9931251}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 9931251 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_9931251}}

	==About this Structure==		==About this Structure==
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	[[Category: Lentivirus]]		[[Category: Lentivirus]]
	[[Category: Viral capsid eiav]]		[[Category: Viral capsid eiav]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 02~~:35:36 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:48:52 2008''