2ewh - Revision history

OCA at 07:40, 23 August 2023

2023-08-23T07:40:34Z

←Older revision		Revision as of 07:40, 23 August 2023
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	<StructureSection load='2ewh' size='340' side='right'caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2ewh' size='340' side='right'caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"thiobacillus_x"_parker_and_prisk_1953 "thiobacillus x" parker and prisk 1953~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [https://pdbe.org/2ewh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [https://www.ebi.ac.uk/pdbsum/2ewh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [https://pdbe.org/2ewh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [https://www.ebi.ac.uk/pdbsum/2ewh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CSOA_HALNC CSOA_HALNC~~]~~] Involved in the formation~~ of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.	+	[https://www.uniprot.org/uniprot/CSOSA_HALNC CSOSA_HALNC] The major shell protein of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, ccbL-ccbS) is sequestered (PubMed:7934888, PubMed:16535117). Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome (PubMed:17518518). The shell probably limits the diffusion of CO(2) into and out of the carboxysome (Probable). Molecular modeling shows the central pore of this protein is selectively permeable to anions such as HCO(3) rather than CO(2) or O(2) (Probable). There are estimated to be 2970 CsoS1A/CsoS1C proteins per carboxysome (the proteins differ by only 1 residue) (Ref.5).<ref>PMID:16535117</ref> <ref>PMID:17518518</ref> <ref>PMID:7934888</ref> <ref>PMID:22184212</ref> <ref>PMID:18258595</ref> <ref>PMID:30193460</ref> Unlike beta-carboxysomes, alpha-carboxysomes (Cb) can form without cargo protein. CsoS2 is essential for Cb formation and is also capable of targeting foreign proteins to the Cb. The Cb shell assembles with the aid of CsoS2; CsoS1A, CsoS1B and CsoS1C form the majority of the shell while CsoS4A and CsoS4B form vertices. CsoS1D forms pseudohexamers that probably control metabolite flux into and out of the shell.<ref>PMID:25826651</ref> <ref>PMID:33116131</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thiobacillus x parker and prisk 1953~~]]	+	[[Category: Halothiobacillus neapolitanus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kerfeld~~, C A~~]]	+	[[Category: Kerfeld CA]]
-	[[Category: Sawaya~~, M R~~]]	+	[[Category: Sawaya MR]]
-	[[Category: Tsai, Y]]	+	[[Category: Tsai Y]]
-	[[Category: Yeates~~, T O]]~~	+	[[Category: Yeates TO]]
-	~~[[Category: Bacterial microcompartment domain]]~~	+
-	~~[[Category: Carboxysome~~]]	+

OCA at 12:32, 10 February 2021

2021-02-10T12:32:25Z

←Older revision		Revision as of 12:32, 10 February 2021
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	==Carboxysome protein CsoS1A from Halothiobacillus neapolitanus==		==Carboxysome protein CsoS1A from Halothiobacillus neapolitanus==
-	<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='2ewh' size='340' side='right'caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"thiobacillus_x"_parker_and_prisk_1953 "thiobacillus x" parker and prisk 1953]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2EWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"thiobacillus_x"_parker_and_prisk_1953 "thiobacillus x" parker and prisk 1953]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [~~http~~://pdbe.org/2ewh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ewh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [https://pdbe.org/2ewh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [https://www.ebi.ac.uk/pdbsum/2ewh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CSOA_HALNC CSOA_HALNC]] Involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.	+	[[https://www.uniprot.org/uniprot/CSOA_HALNC CSOA_HALNC]] Involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ewh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ewh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Thiobacillus x parker and prisk 1953]]		[[Category: Thiobacillus x parker and prisk 1953]]
		+	[[Category: Large Structures]]
	[[Category: Kerfeld, C A]]		[[Category: Kerfeld, C A]]
	[[Category: Sawaya, M R]]		[[Category: Sawaya, M R]]

OCA at 07:29, 18 October 2017

2017-10-18T07:29:42Z

←Older revision		Revision as of 07:29, 18 October 2017
Line 1:		Line 1:
		+
	==Carboxysome protein CsoS1A from Halothiobacillus neapolitanus==		==Carboxysome protein CsoS1A from Halothiobacillus neapolitanus==
	<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://pdbe.org/2ewh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://pdbe.org/2ewh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 05:47, 8 February 2016

2016-02-08T05:47:50Z

←Older revision		Revision as of 05:47, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ewh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:30, 10 September 2015

2015-09-10T08:30:28Z

←Older revision		Revision as of 08:30, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Halothiobacillus_neapolitanus Halothiobacillus neapolitanus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"thiobacillus_x"_parker_and_prisk_1953 "thiobacillus x" parker and prisk 1953]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EWH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 ~~Halothiobacillus neapolitanus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 "Thiobacillus X" Parker and Prisk 1953])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://pdbe.org/2ewh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~CSOA_THINE CSOA_THINE~~]] Involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.	+	[[http://www.uniprot.org/uniprot/CSOA_HALNC CSOA_HALNC]] Involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ewh" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Halothiobacillus neapolitanus~~]]	+	[[Category: Thiobacillus x parker and prisk 1953]]
	[[Category: Kerfeld, C A]]		[[Category: Kerfeld, C A]]
	[[Category: Sawaya, M R]]		[[Category: Sawaya, M R]]

OCA at 21:05, 24 December 2014

2014-12-24T21:05:27Z

←Older revision		Revision as of 21:05, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EWH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 Halothiobacillus neapolitanus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 Halothiobacillus neapolitanus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CSOA_THINE CSOA_THINE]] Involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Halothiobacillus neapolitanus]]		[[Category: Halothiobacillus neapolitanus]]
-	[[Category: Kerfeld, C A.]]	+	[[Category: Kerfeld, C A]]
-	[[Category: Sawaya, M R.]]	+	[[Category: Sawaya, M R]]
-	[[Category: Tsai, Y.]]	+	[[Category: Tsai, Y]]
-	[[Category: Yeates, T O.]]	+	[[Category: Yeates, T O]]
	[[Category: Bacterial microcompartment domain]]		[[Category: Bacterial microcompartment domain]]
	[[Category: Carboxysome]]		[[Category: Carboxysome]]

OCA at 01:44, 30 September 2014

2014-09-30T01:44:01Z

←Older revision		Revision as of 01:44, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2ewh.~~png~~\|~~left~~\|200px]]	+	==Carboxysome protein CsoS1A from Halothiobacillus neapolitanus==
		+	<StructureSection load='2ewh' size='340' side='right' caption='[[2ewh]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EWH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">csoS1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=927 Halothiobacillus neapolitanus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ewh RCSB], [http://www.ebi.ac.uk/pdbsum/2ewh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ewh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The carboxysome is a bacterial organelle that functions to enhance the efficiency of CO2 fixation by encapsulating the enzymes ribulose bisphosphate carboxylase/oxygenase (RuBisCO) and carbonic anhydrase. The outer shell of the carboxysome is reminiscent of a viral capsid, being constructed from many copies of a few small proteins. Here we describe the structure of the shell protein CsoS1A from the chemoautotrophic bacterium Halothiobacillus neapolitanus. The CsoS1A protein forms hexameric units that pack tightly together to form a molecular layer, which is perforated by narrow pores. Sulfate ions, soaked into crystals of CsoS1A, are observed in the pores of the molecular layer, supporting the idea that the pores could be the conduit for negatively charged metabolites such as bicarbonate, which must cross the shell. The problem of diffusion across a semiporous protein shell is discussed, with the conclusion that the shell is sufficiently porous to allow adequate transport of small molecules. The molecular layer formed by CsoS1A is similar to the recently observed layers formed by cyanobacterial carboxysome shell proteins. This similarity supports the argument that the layers observed represent the natural structure of the facets of the carboxysome shell. Insights into carboxysome function are provided by comparisons of the carboxysome shell to viral capsids, and a comparison of its pores to the pores of transmembrane protein channels.

-	~~{{STRUCTURE_2ewh\| PDB=2ewh \| SCENE= }}~~	+	Structural analysis of CsoS1A and the protein shell of the Halothiobacillus neapolitanus carboxysome.,Tsai Y, Sawaya MR, Cannon GC, Cai F, Williams EB, Heinhorst S, Kerfeld CA, Yeates TO PLoS Biol. 2007 Jun;5(6):e144. PMID:17518518<ref>PMID:17518518</ref>

-	~~===Carboxysome protein CsoS1A from Halothiobacillus neapolitanus===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17518518}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2ewh]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017518518<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Halothiobacillus neapolitanus]]		[[Category: Halothiobacillus neapolitanus]]
	[[Category: Kerfeld, C A.]]		[[Category: Kerfeld, C A.]]

OCA: Protected "2ewh" [edit=sysop:move=sysop]

2013-01-06T10:58:44Z

Protected "2ewh" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:58, 6 January 2013

OCA at 10:58, 6 January 2013

2013-01-06T10:58:41Z

←Older revision		Revision as of 10:58, 6 January 2013
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-	{{Seed}}
	[[Image:2ewh.png\|left\|200px]]		[[Image:2ewh.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2ewh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2ewh\| PDB=2ewh \| SCENE= }}		{{STRUCTURE_2ewh\| PDB=2ewh \| SCENE= }}

	===Carboxysome protein CsoS1A from Halothiobacillus neapolitanus===		===Carboxysome protein CsoS1A from Halothiobacillus neapolitanus===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17518518}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17518518 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17518518}}		{{ABSTRACT_PUBMED_17518518}}

	==About this Structure==		==About this Structure==
-	~~2EWH~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA].	+	[[2ewh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17518518~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017518518</ref><references group="xtra"/>
	[[Category: Halothiobacillus neapolitanus]]		[[Category: Halothiobacillus neapolitanus]]
	[[Category: Kerfeld, C A.]]		[[Category: Kerfeld, C A.]]
Line 30:		Line 18:
	[[Category: Yeates, T O.]]		[[Category: Yeates, T O.]]
	[[Category: Bacterial microcompartment domain]]		[[Category: Bacterial microcompartment domain]]
-		+	[[Category: Carboxysome]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 19:26:38 2009''~~	+

OCA at 17:26, 16 February 2009

2009-02-16T17:26:49Z

←Older revision		Revision as of 17:26, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2EWH is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA].	+	2EWH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWH OCA].

	==Reference==		==Reference==
-	Structural analysis of CsoS1A and the protein shell of the Halothiobacillus neapolitanus carboxysome., Tsai Y, Sawaya MR, Cannon GC, Cai F, Williams EB, Heinhorst S, Kerfeld CA, Yeates TO, PLoS Biol. 2007 Jun;5(6):e144. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17518518 17518518]~~	+	<ref group="xtra">PMID:17518518</ref><references group="xtra"/>
	[[Category: Halothiobacillus neapolitanus]]		[[Category: Halothiobacillus neapolitanus]]
-	[[Category: Single protein]]
	[[Category: Kerfeld, C A.]]		[[Category: Kerfeld, C A.]]
	[[Category: Sawaya, M R.]]		[[Category: Sawaya, M R.]]
Line 32:		Line 31:
	[[Category: Bacterial microcompartment domain]]		[[Category: Bacterial microcompartment domain]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 23~~:38:~~48 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:26:38 2009''