2f01 - Revision history

OCA at 07:41, 23 August 2023

2023-08-23T07:41:10Z

←Older revision		Revision as of 07:41, 23 August 2023
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	<StructureSection load='2f01' size='340' side='right'caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>		<StructureSection load='2f01' size='340' side='right'caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_4.1583 As 4.1583~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI~~-~~BIOTIN'>BTQ</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.85Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height~~: ~~3em;~~'>~~[[1mk5\|1mk5]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [https://pdbe.org/2f01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [https://www.ebi.ac.uk/pdbsum/2f01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f01 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [https://pdbe.org/2f01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [https://www.ebi.ac.uk/pdbsum/2f01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).	+	[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: As 4 1583]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Aubert, D G~~]]	+	[[Category: Streptomyces avidinii]]
-	[[Category: ~~Stenkamp, R E]]~~	+	[[Category: Aubert DG]]
-	~~[[Category: Thomas, N R~~]]	+	[[Category: Le Trong I]]
-	[[Category: Trong, I Le]]	+	[[Category: Stenkamp RE]]
-	[[Category: ~~Biotin~~]]	+	[[Category: Thomas NR]]
-	[[Category: ~~Biotin binding protein]]~~	+
-	~~[[Category: Protein/ligand interaction]]~~	+
-	~~[[Category: Streptavidin~~]]	+

OCA at 15:59, 22 December 2021

2021-12-22T15:59:49Z

←Older revision		Revision as of 15:59, 22 December 2021
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	<StructureSection load='2f01' size='340' side='right'caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>		<StructureSection load='2f01' size='340' side='right'caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2F01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mk5\|1mk5]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [~~http~~://pdbe.org/2f01 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2f01 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2f01 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [https://pdbe.org/2f01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [https://www.ebi.ac.uk/pdbsum/2f01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).	+	[[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:44, 18 March 2020

2020-03-18T10:44:04Z

←Older revision		Revision as of 10:44, 18 March 2020
Line 1:		Line 1:

	==Epi-biotin complex with core streptavidin==		==Epi-biotin complex with core streptavidin==
-	<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>	+	<StructureSection load='2f01' size='340' side='right'caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Avidin\|Avidin]]	+	*[[Avidin 3D structures\|Avidin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: As 4 1583]]		[[Category: As 4 1583]]
		+	[[Category: Large Structures]]
	[[Category: Aubert, D G]]		[[Category: Aubert, D G]]
	[[Category: Stenkamp, R E]]		[[Category: Stenkamp, R E]]

OCA at 08:24, 14 June 2018

2018-06-14T08:24:26Z

←Older revision		Revision as of 08:24, 14 June 2018
Line 1:		Line 1:
		+
	==Epi-biotin complex with core streptavidin==		==Epi-biotin complex with core streptavidin==
	<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>		<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://pdbe.org/2f01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://pdbe.org/2f01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2f01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f01_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f01_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f01 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:59, 12 September 2015

2015-09-12T01:59:36Z

←Older revision		Revision as of 01:59, 12 September 2015
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	<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>		<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_avidinii Streptomyces avidinii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://pdbe.org/2f01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2f01" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces avidinii~~]]	+	[[Category: As 4 1583]]
	[[Category: Aubert, D G]]		[[Category: Aubert, D G]]
	[[Category: Stenkamp, R E]]		[[Category: Stenkamp, R E]]

OCA at 22:22, 25 December 2014

2014-12-25T22:22:39Z

←Older revision		Revision as of 22:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Streptomyces avidinii]]		[[Category: Streptomyces avidinii]]
-	[[Category: Aubert, D G.]]	+	[[Category: Aubert, D G]]
-	[[Category: Stenkamp, R E.]]	+	[[Category: Stenkamp, R E]]
-	[[Category: Thomas, N R.]]	+	[[Category: Thomas, N R]]
-	[[Category: Trong, I Le.]]	+	[[Category: Trong, I Le]]
	[[Category: Biotin]]		[[Category: Biotin]]
	[[Category: Biotin binding protein]]		[[Category: Biotin binding protein]]
	[[Category: Protein/ligand interaction]]		[[Category: Protein/ligand interaction]]
	[[Category: Streptavidin]]		[[Category: Streptavidin]]

OCA at 09:27, 29 September 2014

2014-09-29T09:27:57Z

←Older revision		Revision as of 09:27, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2f01.~~png~~\|~~left~~\|200px]]	+	==Epi-biotin complex with core streptavidin==
		+	<StructureSection load='2f01' size='340' side='right' caption='[[2f01]], [[Resolution\|resolution]] 0.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F01 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1mk5\|1mk5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f01 RCSB], [http://www.ebi.ac.uk/pdbsum/2f01 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f01_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	(+)-Epi-biotin differs from (+)-biotin in the configuration of the chiral center at atom C2. This could lead to a difference in the mode of binding of (+)-epi-biotin to streptavidin, a natural protein receptor for (+)-biotin. Diffraction data were collected to a maximum of 0.85 Angstrom resolution for structural analysis of the complex of streptavidin with a sample of (+)-epi-biotin and refinement was carried out at both 1.0 and 0.85 Angstrom resolution. The structure determination shows a superposition of two ligands in the binding site, (+)-biotin and (+)-epi-biotin. The molecules overlap in the model for the complex except for the position of S1 in the tetrahydrothiophene ring. Differences in the conformation of the ring permits binding of each molecule to streptavidin with little observable difference in the protein structures at this high resolution.

-	~~{{STRUCTURE_2f01\| PDB=2f01 \| SCENE= }}~~	+	The high-resolution structure of (+)-epi-biotin bound to streptavidin.,Le Trong I, Aubert DG, Thomas NR, Stenkamp RE Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):576-81. Epub 2006, May 12. PMID:16699183<ref>PMID:16699183</ref>

-	~~===Epi-biotin complex with core streptavidin===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16699183}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2f01]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_avidinii Streptomyces avidinii]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA].~~	+

	==See Also==		==See Also==
	*[[Avidin\|Avidin]]		*[[Avidin\|Avidin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016699183<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces avidinii]]		[[Category: Streptomyces avidinii]]
	[[Category: Aubert, D G.]]		[[Category: Aubert, D G.]]

OCA at 22:21, 20 October 2012

2012-10-20T22:21:00Z

←Older revision		Revision as of 22:21, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2f01]] is a 2 chain structure ~~of [[Avidin]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA].	+	[[2f01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA].

	==See Also==		==See Also==

OCA: Protected "2f01" [edit=sysop:move=sysop]

2012-07-27T16:00:44Z

Protected "2f01" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:00, 27 July 2012

OCA at 16:00, 27 July 2012

2012-07-27T16:00:42Z

←Older revision		Revision as of 16:00, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2f01.png\|left\|200px]]		[[Image:2f01.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2f01", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2f01\| PDB=2f01 \| SCENE= }}		{{STRUCTURE_2f01\| PDB=2f01 \| SCENE= }}

	===Epi-biotin complex with core streptavidin===		===Epi-biotin complex with core streptavidin===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16699183}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16699183 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16699183}}		{{ABSTRACT_PUBMED_16699183}}

	==About this Structure==		==About this Structure==
-	~~2F01~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA].	+	[[2f01]] is a 2 chain structure of [[Avidin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F01 OCA].
		+
		+	==See Also==
		+	*[[Avidin\|Avidin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16699183~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016699183</ref><references group="xtra"/>
	[[Category: Streptomyces avidinii]]		[[Category: Streptomyces avidinii]]
	[[Category: Aubert, D G.]]		[[Category: Aubert, D G.]]
Line 30:		Line 21:
	[[Category: Trong, I Le.]]		[[Category: Trong, I Le.]]
	[[Category: Biotin]]		[[Category: Biotin]]
		+	[[Category: Biotin binding protein]]
	[[Category: Protein/ligand interaction]]		[[Category: Protein/ligand interaction]]
	[[Category: Streptavidin]]		[[Category: Streptavidin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:38:35 2009''