2f2b - Revision history

OCA at 07:41, 23 August 2023

2023-08-23T07:41:49Z

←Older revision		Revision as of 07:41, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='2f2b' size='340' side='right'caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='2f2b' size='340' side='right'caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Mettm Mettm~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._Marburg Methanothermobacter marburgensis str. Marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2B FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.68Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[2evu\|2evu]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">aqpM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [https://pdbe.org/2f2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [https://www.ebi.ac.uk/pdbsum/2f2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [https://pdbe.org/2f2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [https://www.ebi.ac.uk/pdbsum/2f2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM]] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.	+	[https://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mettm~~]]	+	[[Category: Methanothermobacter marburgensis str. Marburg]]
-	[[Category: Agre, P]]	+	[[Category: Agre P]]
-	~~[[Category: CSMP, Center for Structures of Membrane Proteins~~]]	+	[[Category: Kitagawa Y]]
-	[[Category: Kitagawa, Y]]	+	[[Category: Kozono D]]
-	[[Category: Kozono, D]]	+	[[Category: Lee JK]]
-	[[Category: Lee~~, J K~~]]	+	[[Category: Remis J]]
-	[[Category: Remis, J]]	+	[[Category: Stroud RM]]
-	[[Category: Stroud~~, R M]]~~	+
-	~~[[Category: Center for structures of membrane protein]]~~	+
-	~~[[Category: Channel]]~~	+
-	~~[[Category: Csmp]]~~	+
-	~~[[Category: Integral membrane protein]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Protein]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Structural genomic~~]]	+

OCA at 10:36, 17 February 2021

2021-02-17T10:36:55Z

←Older revision		Revision as of 10:36, 17 February 2021
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	==Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution==		==Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution==
-	<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>	+	<StructureSection load='2f2b' size='340' side='right'caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mettm Mettm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2F2B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mettm Mettm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2evu\|2evu]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [~~http~~://pdbe.org/2f2b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2f2b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [https://pdbe.org/2f2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [https://www.ebi.ac.uk/pdbsum/2f2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM]] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.	+	[[https://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM]] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Aquaporin\|Aquaporin]]	+	*[[Aquaporin 3D structures\|Aquaporin 3D structures]]
-	*[[Nobel Prizes for 3D Molecular Structure\|Nobel Prizes for 3D ~~Molecular Structure~~]]	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mettm]]		[[Category: Mettm]]
	[[Category: Agre, P]]		[[Category: Agre, P]]

OCA at 09:23, 14 June 2018

2018-06-14T09:23:31Z

←Older revision		Revision as of 09:23, 14 June 2018
Line 1:		Line 1:
		+
	==Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution==		==Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution==
	<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://pdbe.org/2f2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://pdbe.org/2f2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2b_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2b_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:00, 8 February 2016

2016-02-08T14:00:53Z

←Older revision		Revision as of 14:00, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2b ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:15, 10 September 2015

2015-09-10T12:15:59Z

←Older revision		Revision as of 12:15, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mettm Mettm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 ~~Methanothermobacter marburgensis str. Marburg~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 METTM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://pdbe.org/2f2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2f2b" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanothermobacter marburgensis str. marburg~~]]	+	[[Category: Mettm]]
	[[Category: Agre, P]]		[[Category: Agre, P]]
	[[Category: CSMP, Center for Structures of Membrane Proteins]]		[[Category: CSMP, Center for Structures of Membrane Proteins]]

OCA at 23:50, 24 December 2014

2014-12-24T23:50:57Z

←Older revision		Revision as of 23:50, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2B FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2B FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 Methanothermobacter marburgensis str. Marburg])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 Methanothermobacter marburgensis str. Marburg])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AQPM_METTM AQPM_METTM]] Channel that permits osmotically driven movement of water in both directions. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Exhibits also a transient but reproducible increase in the initial glycerol flux.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Methanothermobacter marburgensis str. marburg]]		[[Category: Methanothermobacter marburgensis str. marburg]]
-	[[Category: Agre, P.]]	+	[[Category: Agre, P]]
-	[[Category: CSMP, Center for Structures of Membrane Proteins.]]	+	[[Category: CSMP, Center for Structures of Membrane Proteins]]
-	[[Category: Kitagawa, Y.]]	+	[[Category: Kitagawa, Y]]
-	[[Category: Kozono, D.]]	+	[[Category: Kozono, D]]
-	[[Category: Lee, J K.]]	+	[[Category: Lee, J K]]
-	[[Category: Remis, J.]]	+	[[Category: Remis, J]]
-	[[Category: Stroud, R M.]]	+	[[Category: Stroud, R M]]
	[[Category: Center for structures of membrane protein]]		[[Category: Center for structures of membrane protein]]
	[[Category: Channel]]		[[Category: Channel]]
Line 48:		Line 50:
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Protein]]		[[Category: Protein]]
-	[[Category: Protein structure initiative]]	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category: Psi-2~~]]	+
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 02:14, 30 September 2014

2014-09-30T02:14:14Z

←Older revision		Revision as of 02:14, 30 September 2014
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-	~~{{STRUCTURE_2f2b\| PDB=2f2b \| SCENE= }}~~	+	==Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution==
-	===Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution===	+	<StructureSection load='2f2b' size='340' side='right' caption='[[2f2b]], [[Resolution\|resolution]] 1.68Å' scene=''>
-	~~{{ABSTRACT_PUBMED_16361443}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2B FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2evu\|2evu]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aqpM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79929 Methanothermobacter marburgensis str. Marburg])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f2b RCSB], [http://www.ebi.ac.uk/pdbsum/2f2b PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2b_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To explore the structural basis of the unique selectivity spectrum and conductance of the transmembrane channel protein AqpM from the archaeon Methanothermobacter marburgensis, we determined the structure of AqpM to 1.68-A resolution by x-ray crystallography. The structure establishes AqpM as being in a unique subdivision between the two major subdivisions of aquaporins, the water-selective aquaporins, and the water-plus-glycerol-conducting aquaglyceroporins. In AqpM, isoleucine replaces a key histidine residue found in the lumen of water channels, which becomes a glycine residue in aquaglyceroporins. As a result of this and other side-chain substituents in the walls of the channel, the channel is intermediate in size and exhibits differentially tuned electrostatics when compared with the other subfamilies.

-	~~==About this Structure==~~	+	Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.,Lee JK, Kozono D, Remis J, Kitagawa Y, Agre P, Stroud RM Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18932-7. Epub 2005 Dec 16. PMID:16361443<ref>PMID:16361443</ref>
-	~~[[2f2b]] is a~~ 1 ~~chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanothermobacter_marburgensis_str~~.~~_marburg Methanothermobacter marburgensis str~~. ~~marburg]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2F2B OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Aquaporin\|Aquaporin]]		*[[Aquaporin\|Aquaporin]]
	*[[Nobel Prizes for 3D Molecular Structure\|Nobel Prizes for 3D Molecular Structure]]		*[[Nobel Prizes for 3D Molecular Structure\|Nobel Prizes for 3D Molecular Structure]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016361443<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Methanothermobacter marburgensis str. marburg]]		[[Category: Methanothermobacter marburgensis str. marburg]]
	[[Category: Agre, P.]]		[[Category: Agre, P.]]

OCA at 10:41, 11 March 2013

2013-03-11T10:41:48Z

←Older revision		Revision as of 10:41, 11 March 2013
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-	[[Image:2f2b.png\|left\|200px]]
-
	{{STRUCTURE_2f2b\| PDB=2f2b \| SCENE= }}		{{STRUCTURE_2f2b\| PDB=2f2b \| SCENE= }}
-
	===Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution===		===Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution===
-
	{{ABSTRACT_PUBMED_16361443}}		{{ABSTRACT_PUBMED_16361443}}

OCA at 12:06, 7 January 2013

2013-01-07T12:06:19Z

←Older revision		Revision as of 12:06, 7 January 2013
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	[[Image:2f2b.png\|left\|200px]]		[[Image:2f2b.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2f2b", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2f2b\| PDB=2f2b \| SCENE= }}		{{STRUCTURE_2f2b\| PDB=2f2b \| SCENE= }}

	===Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution===		===Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16361443}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16361443 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16361443}}		{{ABSTRACT_PUBMED_16361443}}

	==About this Structure==		==About this Structure==
-	[[2f2b]] is a 1 chain structure ~~of [[Aquaporin]]~~ with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA].	+	[[2f2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_marburgensis_str._marburg Methanothermobacter marburgensis str. marburg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2B OCA].

	==See Also==		==See Also==
-	*[[Aquaporin]]	+	*[[Aquaporin\|Aquaporin]]
		+	*[[Nobel Prizes for 3D Molecular Structure\|Nobel Prizes for 3D Molecular Structure]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16361443~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016361443</ref><references group="xtra"/>
	[[Category: Methanothermobacter marburgensis str. marburg]]		[[Category: Methanothermobacter marburgensis str. marburg]]
	[[Category: Agre, P.]]		[[Category: Agre, P.]]
Line 38:		Line 28:
	[[Category: Csmp]]		[[Category: Csmp]]
	[[Category: Integral membrane protein]]		[[Category: Integral membrane protein]]
		+	[[Category: Membrane protein]]
	[[Category: Protein]]		[[Category: Protein]]
	[[Category: Protein structure initiative]]		[[Category: Protein structure initiative]]
	[[Category: Psi-2]]		[[Category: Psi-2]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA: Protected "2f2b" [edit=sysop:move=sysop]

2010-12-26T22:10:42Z

Protected "2f2b" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:10, 26 December 2010