2f5a - Revision history

OCA at 07:43, 23 August 2023

2023-08-23T07:43:17Z

←Older revision		Revision as of 07:43, 23 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [https://pdbe.org/2f5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [https://www.ebi.ac.uk/pdbsum/2f5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5a ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [https://pdbe.org/2f5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [https://www.ebi.ac.uk/pdbsum/2f5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5a ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 32:
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bryson, S]]	+	[[Category: Bryson S]]
-	[[Category: Hynes~~, R C~~]]	+	[[Category: Hynes RC]]
-	[[Category: Julien~~, J P~~]]	+	[[Category: Julien JP]]
-	[[Category: Pai~~, E F]]~~	+	[[Category: Pai EF]]
-	~~[[Category: Fab]]~~	+
-	~~[[Category: Gp41]]~~	+
-	~~[[Category: Hiv-1 neutralization]]~~	+
-	~~[[Category: Immunoglobulin~~]]	+

OCA at 16:01, 22 December 2021

2021-12-22T16:01:12Z

←Older revision		Revision as of 16:01, 22 December 2021
Line 3:		Line 3:
	<StructureSection load='2f5a' size='340' side='right'caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2f5a' size='340' side='right'caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2F5A FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [~~http~~://pdbe.org/2f5a PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2f5a PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5a ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [https://pdbe.org/2f5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [https://www.ebi.ac.uk/pdbsum/2f5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5a ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:45, 18 March 2020

2020-03-18T10:45:51Z

←Older revision		Revision as of 10:45, 18 March 2020
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5==		==CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5==
-	<StructureSection load='2f5a' size='340' side='right' caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='2f5a' size='340' side='right'caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
	[[Category: Bryson, S]]		[[Category: Bryson, S]]
	[[Category: Hynes, R C]]		[[Category: Hynes, R C]]

OCA at 09:13, 14 June 2018

2018-06-14T09:13:10Z

←Older revision		Revision as of 09:13, 14 June 2018
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5==		==CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5==
	<StructureSection load='2f5a' size='340' side='right' caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2f5a' size='340' side='right' caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://pdbe.org/2f5a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://pdbe.org/2f5a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5a ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f5a_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f5a_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 00:22, 10 February 2016

2016-02-10T00:22:26Z

←Older revision		Revision as of 00:22, 10 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f5a ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:30, 11 September 2015

2015-09-11T03:30:54Z

←Older revision		Revision as of 03:30, 11 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://pdbe.org/2f5a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2f5a" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:34, 16 January 2015

2015-01-16T08:34:25Z

←Older revision		Revision as of 08:34, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>		<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Bryson, S.]]	+	[[Category: Bryson, S]]
-	[[Category: Hynes, R C.]]	+	[[Category: Hynes, R C]]
-	[[Category: Julien, J P.]]	+	[[Category: Julien, J P]]
-	[[Category: Pai, E F.]]	+	[[Category: Pai, E F]]
	[[Category: Fab]]		[[Category: Fab]]
	[[Category: Gp41]]		[[Category: Gp41]]
	[[Category: Hiv-1 neutralization]]		[[Category: Hiv-1 neutralization]]
	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]

OCA at 02:05, 30 September 2014

2014-09-30T02:05:53Z

←Older revision		Revision as of 02:05, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2f5a.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5==
		+	<StructureSection load='2f5a' size='340' side='right' caption='[[2f5a]], [[Resolution\|resolution]] 2.05Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F5A FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f5a RCSB], [http://www.ebi.ac.uk/pdbsum/2f5a PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f5a_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The quest to create a human immunodeficiency virus type 1 (HIV-1) vaccine capable of eliciting broadly neutralizing antibodies against Env has been challenging. Among other problems, one difficulty in creating a potent immunogen resides in the substantial overall sequence variability of the HIV envelope protein. The membrane-proximal region (MPER) of gp41 is a particularly conserved tryptophan-rich region spanning residues 659 to 683, which is recognized by three broadly neutralizing monoclonal antibodies (bnMAbs), 2F5, Z13, and 4E10. In this study, we first describe the variability of residues in the gp41 MPER and report on the invariant nature of 15 out of 25 amino acids comprising this region. Subsequently, we evaluate the ability of the bnMAb 2F5 to recognize 31 varying sequences of the gp41 MPER at a molecular level. In 19 cases, resulting crystal structures show the various MPER peptides bound to the 2F5 Fab'. A variety of amino acid substitutions outside the 664DKW666 core epitope are tolerated. However, changes at the 664DKW666 motif itself are restricted to those residues that preserve the aspartate's negative charge, the hydrophobic alkyl-pi stacking arrangement between the beta-turn lysine and tryptophan, and the positive charge of the former. We also characterize a possible molecular mechanism of 2F5 escape by sequence variability at position 667, which is often observed in HIV-1 clade C isolates. Based on our results, we propose a somewhat more flexible molecular model of epitope recognition by bnMAb 2F5, which could guide future attempts at designing small-molecule MPER-like vaccines capable of eliciting 2F5-like antibodies.

-	~~{{STRUCTURE_2f5a\| PDB=2f5a \| SCENE= }}~~	+	Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.,Bryson S, Julien JP, Hynes RC, Pai EF J Virol. 2009 Nov;83(22):11862-75. Epub 2009 Sep 9. PMID:19740978<ref>PMID:19740978</ref>

-	~~===CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19740978}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2f5a]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019740978<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bryson, S.]]		[[Category: Bryson, S.]]

OCA: Protected "2f5a" [edit=sysop:move=sysop]

2013-01-07T14:37:10Z

Protected "2f5a" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:37, 7 January 2013

OCA at 14:37, 7 January 2013

2013-01-07T14:37:05Z

←Older revision		Revision as of 14:37, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2f5a.png\|left\|200px]]		[[Image:2f5a.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2f5a", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2f5a\| PDB=2f5a \| SCENE= }}		{{STRUCTURE_2f5a\| PDB=2f5a \| SCENE= }}

	===CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5===		===CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19740978}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19740978 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19740978}}		{{ABSTRACT_PUBMED_19740978}}

	==About this Structure==		==About this Structure==
-	~~2F5A~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA].	+	[[2f5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5A OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19740978~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019740978</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bryson, S.]]		[[Category: Bryson, S.]]
Line 33:		Line 21:
	[[Category: Hiv-1 neutralization]]		[[Category: Hiv-1 neutralization]]
	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]
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-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 13:58:35 2009''