2ft9 - Revision history

OCA at 08:45, 25 October 2023

2023-10-25T08:45:16Z

←Older revision		Revision as of 08:45, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2ftb\|2ftb]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [https://pdbe.org/2ft9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ft9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ft9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [https://pdbe.org/2ft9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ft9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ft9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/FABP2_AMBME FABP2_AMBME]] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). The specificity of axolotl L-FABP differs from that of LB-FABP. Binds 2 ligands per protein molecule.	+	[https://www.uniprot.org/uniprot/FABP2_AMBME FABP2_AMBME] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). The specificity of axolotl L-FABP differs from that of LB-FABP. Binds 2 ligands per protein molecule.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 38:
	[[Category: Ambystoma mexicanum]]		[[Category: Ambystoma mexicanum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Capaldi, S]]	+	[[Category: Capaldi S]]
-	[[Category: ~~Guariento, M~~]]	+	[[Category: Di Pietro SM]]
-	[[Category: ~~Monaco, H L~~]]	+	[[Category: Guariento M]]
-	[[Category: ~~Perduca, M~~]]	+	[[Category: Monaco HL]]
-	[[Category: ~~Pietro, S~~ M~~.Di~~]]	+	[[Category: Perduca M]]
-	[[Category: Santome~~, J A]]~~	+	[[Category: Santome JA]]
-	~~[[Category: Axolotl]]~~	+
-	~~[[Category: Cholic acid]]~~	+
-	~~[[Category: Lipid binding protein]]~~	+
-	~~[[Category: Liver basic fatty acid-binding protein]]~~	+
-	~~[[Category: Liver bile acid-binding protein~~]]	+

OCA at 14:36, 29 December 2021

2021-12-29T14:36:59Z

←Older revision		Revision as of 14:36, 29 December 2021
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	<StructureSection load='2ft9' size='340' side='right'caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ft9' size='340' side='right'caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ftb\|2ftb]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [~~http~~://pdbe.org/2ft9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ft9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ft9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [https://pdbe.org/2ft9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ft9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ft9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FABP2_AMBME FABP2_AMBME]] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). The specificity of axolotl L-FABP differs from that of LB-FABP. Binds 2 ligands per protein molecule.	+	[[https://www.uniprot.org/uniprot/FABP2_AMBME FABP2_AMBME]] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). The specificity of axolotl L-FABP differs from that of LB-FABP. Binds 2 ligands per protein molecule.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:05, 27 March 2020

2020-03-27T11:05:18Z

←Older revision		Revision as of 11:05, 27 March 2020
Line 1:		Line 1:

	==Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid==		==Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid==
-	<StructureSection load='2ft9' size='340' side='right' caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2ft9' size='340' side='right'caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]	+	*[[Fatty acid-binding protein 3D structures\|Fatty acid-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Ambystoma mexicanum]]		[[Category: Ambystoma mexicanum]]
		+	[[Category: Large Structures]]
	[[Category: Capaldi, S]]		[[Category: Capaldi, S]]
	[[Category: Guariento, M]]		[[Category: Guariento, M]]

OCA at 07:14, 20 June 2018

2018-06-20T07:14:06Z

←Older revision		Revision as of 07:14, 20 June 2018
Line 1:		Line 1:
		+
	==Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid==		==Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid==
	<StructureSection load='2ft9' size='340' side='right' caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ft9' size='340' side='right' caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://pdbe.org/2ft9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://pdbe.org/2ft9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ft9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/2ft9_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/2ft9_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ft9 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:14, 11 September 2015

2015-09-11T16:14:32Z

←Older revision		Revision as of 16:14, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://pdbe.org/2ft9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ft9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:52, 25 December 2014

2014-12-25T18:52:34Z

←Older revision		Revision as of 18:52, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FABP2_AMBME FABP2_AMBME]] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity). The specificity of axolotl L-FABP differs from that of LB-FABP. Binds 2 ligands per protein molecule.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Ambystoma mexicanum]]		[[Category: Ambystoma mexicanum]]
-	[[Category: Capaldi, S.]]	+	[[Category: Capaldi, S]]
-	[[Category: Guariento, M.]]	+	[[Category: Guariento, M]]
-	[[Category: Monaco, H L.]]	+	[[Category: Monaco, H L]]
-	[[Category: Perduca, M.]]	+	[[Category: Perduca, M]]
-	[[Category: Pietro, S M.Di.]]	+	[[Category: Pietro, S M.Di]]
-	[[Category: Santome, J A.]]	+	[[Category: Santome, J A]]
	[[Category: Axolotl]]		[[Category: Axolotl]]
	[[Category: Cholic acid]]		[[Category: Cholic acid]]

OCA at 10:11, 29 September 2014

2014-09-29T10:11:13Z

←Older revision		Revision as of 10:11, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2ft9.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid==
		+	<StructureSection load='2ft9' size='340' side='right' caption='[[2ft9]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FT9 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ftb\|2ftb]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ft9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ft9 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/2ft9_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The family of the liver bile acid-binding proteins (L-BABPs), formerly called liver basic fatty acid-binding proteins (Lb-FABPs) shares fold and sequence similarity with the paralogous liver fatty acid-binding proteins (L-FABPs) but has a different stoichiometry and specificity of ligand binding. This article describes the first X-ray structure of a member of the L-BABP family, axolotl (Ambystoma mexicanum) L-BABP, bound to two different ligands: cholic and oleic acid. The protein binds one molecule of oleic acid in a position that is significantly different from that of either of the two molecules that bind to rat liver FABP. The stoichiometry of binding of cholate is of two ligands per protein molecule, as observed in chicken L-BABP. The cholate molecule that binds buried most deeply into the internal cavity overlaps well with the analogous bound to chicken L-BABP, whereas the second molecule, which interacts with the first only through hydrophobic contacts, is more external and exposed to the solvent.

-	~~{{STRUCTURE_2ft9\| PDB=2ft9 \| SCENE= }}~~	+	Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic and oleic acid.,Capaldi S, Guariento M, Perduca M, Di Pietro SM, Santome JA, Monaco HL Proteins. 2006 Jul 1;64(1):79-88. PMID:16555310<ref>PMID:16555310</ref>

-	~~===Crystal structure~~ of ~~axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16555310}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2ft9]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA].~~	+

	==See Also==		==See Also==
	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]		*[[Fatty acid-binding protein\|Fatty acid-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016555310<~~/~~ref~~><~~ref group="xtra">PMID:011717512</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Ambystoma mexicanum]]		[[Category: Ambystoma mexicanum]]
	[[Category: Capaldi, S.]]		[[Category: Capaldi, S.]]

OCA at 20:12, 20 October 2012

2012-10-20T20:12:23Z

←Older revision		Revision as of 20:12, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2ft9]] is a 1 chain structure ~~of [[Fatty acid-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA].	+	[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA].

	==See Also==		==See Also==

OCA at 09:44, 27 July 2012

2012-07-27T09:44:11Z

←Older revision		Revision as of 09:44, 27 July 2012
Line 1:		Line 1:
	[[Image:2ft9.png\|left\|200px]]		[[Image:2ft9.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2ft9\| PDB=2ft9 \| SCENE= }}		{{STRUCTURE_2ft9\| PDB=2ft9 \| SCENE= }}

	===Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid===		===Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic acid===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16555310}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16555310 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16555310}}		{{ABSTRACT_PUBMED_16555310}}

	==About this Structure==		==About this Structure==
-	[[2ft9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA].	+	[[2ft9]] is a 1 chain structure of [[Fatty acid-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Ambystoma_mexicanum Ambystoma mexicanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FT9 OCA].
		+
		+	==See Also==
		+	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16555310~~</ref><ref group="xtra">PMID:~~11717512~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016555310</ref><ref group="xtra">PMID:011717512</ref><references group="xtra"/>
	[[Category: Ambystoma mexicanum]]		[[Category: Ambystoma mexicanum]]
	[[Category: Capaldi, S.]]		[[Category: Capaldi, S.]]

OCA: Protected "2ft9" [edit=sysop:move=sysop]

2011-03-15T00:07:25Z

Protected "2ft9" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:07, 15 March 2011