2g0e - Revision history

OCA at 09:26, 14 February 2024

2024-02-14T09:26:07Z

←Older revision		Revision as of 09:26, 14 February 2024
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	<StructureSection load='2g0e' size='340' side='right'caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>		<StructureSection load='2g0e' size='340' side='right'caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_29970 Atcc 29970~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G0E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G0E FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CGQ:3~~-[C-[~~N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO~~]~~-[[AMINOMETHYLIDENE~~]~~AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.88Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;'>~~[[~~1jt6\|1jt6~~]], [[~~1jtx\|1jtx~~]]~~</div~~></td><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">qacR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [https://pdbe.org/2g0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [https://www.ebi.ac.uk/pdbsum/2g0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g0e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [https://pdbe.org/2g0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [https://www.ebi.ac.uk/pdbsum/2g0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g0e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/QACR_STAHA QACR_STAHA]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).	+	[https://www.uniprot.org/uniprot/QACR_STAHA QACR_STAHA] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 29970]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Schuman, J T~~]]	+	[[Category: Staphylococcus haemolyticus]]
-	[[Category: ~~Helix-turn-helix]]~~	+	[[Category: Schuman JT]]
-	~~[[Category: Transciptional repressor]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Trivalent~~]]	+

OCA at 15:37, 3 March 2021

2021-03-03T15:37:14Z

←Older revision		Revision as of 15:37, 3 March 2021
Line 1:		Line 1:

	==Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs==		==Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs==
-	<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>	+	<StructureSection load='2g0e' size='340' side='right'caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_29970 Atcc 29970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2G0E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_29970 Atcc 29970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G0E FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jt6\|1jt6]], [[1jtx\|1jtx]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [~~http~~://pdbe.org/2g0e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2g0e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2g0e ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [https://pdbe.org/2g0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [https://www.ebi.ac.uk/pdbsum/2g0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g0e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/QACR_STAHA QACR_STAHA]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).	+	[[https://www.uniprot.org/uniprot/QACR_STAHA QACR_STAHA]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g0e ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g0e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Tetracycline repressor protein 3D structures\|Tetracycline repressor protein 3D structures]]
		+	*[[Transcriptional activator 3D structures\|Transcriptional activator 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Atcc 29970]]		[[Category: Atcc 29970]]
		+	[[Category: Large Structures]]
	[[Category: Schuman, J T]]		[[Category: Schuman, J T]]
	[[Category: Helix-turn-helix]]		[[Category: Helix-turn-helix]]

OCA at 07:05, 20 June 2018

2018-06-20T07:05:01Z

←Older revision		Revision as of 07:05, 20 June 2018
Line 1:		Line 1:
		+
	==Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs==		==Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs==
	<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>		<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://pdbe.org/2g0e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://pdbe.org/2g0e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2g0e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/2g0e_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/2g0e_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:48, 8 February 2016

2016-02-08T16:48:31Z

←Older revision		Revision as of 16:48, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g0e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 13:32, 10 September 2015

2015-09-10T13:32:48Z

←Older revision		Revision as of 13:32, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>		<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_haemolyticus Staphylococcus haemolyticus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G0E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29970 Atcc 29970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G0E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ~~Staphylococcus haemolyticus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 ATCC 29970])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://pdbe.org/2g0e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staphylococcus haemolyticus~~]]	+	[[Category: Atcc 29970]]
	[[Category: Schuman, J T]]		[[Category: Schuman, J T]]
	[[Category: Helix-turn-helix]]		[[Category: Helix-turn-helix]]

OCA at 00:47, 25 December 2014

2014-12-25T00:47:18Z

←Older revision		Revision as of 00:47, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G0E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G0E FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 Staphylococcus haemolyticus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 Staphylococcus haemolyticus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/QACR_STAHA QACR_STAHA]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Staphylococcus haemolyticus]]		[[Category: Staphylococcus haemolyticus]]
-	[[Category: Schuman, J T.]]	+	[[Category: Schuman, J T]]
	[[Category: Helix-turn-helix]]		[[Category: Helix-turn-helix]]
	[[Category: Transciptional repressor]]		[[Category: Transciptional repressor]]
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Trivalent]]		[[Category: Trivalent]]

OCA at 08:01, 30 September 2014

2014-09-30T08:01:35Z

←Older revision		Revision as of 08:01, 30 September 2014
Line 1:		Line 1:
-	~~[[Image:2g0e.png\|left\|200px]]~~	+	==Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs==
-		+	<StructureSection load='2g0e' size='340' side='right' caption='[[2g0e]], [[Resolution\|resolution]] 2.88Å' scene=''>
-	~~{{STRUCTURE_2g0e\| PDB=2g0e \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G0E FirstGlance]. <br>
-	===Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CGQ:3-[C-[N-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1jt6\|1jt6]], [[1jtx\|1jtx]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">qacR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 Staphylococcus haemolyticus])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0e RCSB], [http://www.ebi.ac.uk/pdbsum/2g0e PDBsum]</span></td></tr>
-	[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA].	+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/2g0e_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Staphylococcus haemolyticus]]		[[Category: Staphylococcus haemolyticus]]
	[[Category: Schuman, J T.]]		[[Category: Schuman, J T.]]

OCA: Protected "2g0e" [edit=sysop:move=sysop]

2013-01-07T13:06:34Z

Protected "2g0e" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:06, 7 January 2013

OCA at 13:06, 7 January 2013

2013-01-07T13:06:33Z

←Older revision		Revision as of 13:06, 7 January 2013
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-	{{Seed}}
	[[Image:2g0e.png\|left\|200px]]		[[Image:2g0e.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2g0e", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2g0e\| PDB=2g0e \| SCENE= }}		{{STRUCTURE_2g0e\| PDB=2g0e \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2G0E~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA].	+	[[2g0e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA].
	[[Category: Staphylococcus haemolyticus]]		[[Category: Staphylococcus haemolyticus]]
	[[Category: Schuman, J T.]]		[[Category: Schuman, J T.]]
Line 21:		Line 14:
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Trivalent]]		[[Category: Trivalent]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:34:01 2009''

OCA at 22:34, 16 February 2009

2009-02-16T22:34:01Z

←Older revision		Revision as of 22:34, 16 February 2009
Line 1:		Line 1:
-	[[Image:2g0e.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2g0e.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2g0e\| PDB=2g0e \| SCENE= }}		{{STRUCTURE_2g0e\| PDB=2g0e \| SCENE= }}

-	~~'''~~Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs~~'''~~	+	===Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs===


	==About this Structure==		==About this Structure==
-	2G0E is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA].	+	2G0E is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G0E OCA].
-	~~[[Category: Single protein]]~~	+
	[[Category: Staphylococcus haemolyticus]]		[[Category: Staphylococcus haemolyticus]]
	[[Category: Schuman, J T.]]		[[Category: Schuman, J T.]]
Line 21:		Line 21:
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Trivalent]]		[[Category: Trivalent]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:34:01 2009''