2go5 - Revision history

OCA at 10:22, 12 January 2022

2022-01-12T10:22:43Z

←Older revision		Revision as of 10:22, 12 January 2022
Line 3:		Line 3:
	<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>		<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [~~http~~://en.wikipedia.org/wiki/Human Human], [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [~~http~~://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [https://en.wikipedia.org/wiki/Human Human], [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [https://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [~~http~~://pdbe.org/2go5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [https://pdbe.org/2go5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [https://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SRPRB_MOUSE SRPRB_MOUSE]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. [[~~http~~://www.uniprot.org/uniprot/SRP54_CANFA SRP54_CANFA]] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). [[~~http~~://www.uniprot.org/uniprot/SRPR_HUMAN SRPR_HUMAN]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.	+	[[https://www.uniprot.org/uniprot/SRPRB_MOUSE SRPRB_MOUSE]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. [[https://www.uniprot.org/uniprot/SRP54_CANFA SRP54_CANFA]] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). [[https://www.uniprot.org/uniprot/SRPR_HUMAN SRPR_HUMAN]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:52, 10 April 2020

2020-04-10T16:52:23Z

←Older revision		Revision as of 16:52, 10 April 2020
Line 3:		Line 3:
	<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>		<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 16:54, 6 March 2020

2020-03-06T16:54:09Z

←Older revision		Revision as of 16:54, 6 March 2020
Line 1:		Line 1:

	==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==		==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==
-	<~~StructureSection~~ load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>	+	<SX load='2go5' size='340' side='right' viewer='molstar' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
Line 36:		Line 36:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Canis sp]]		[[Category: Canis sp]]
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Triticum sp]]		[[Category: Triticum sp]]

OCA at 06:54, 20 June 2018

2018-06-20T06:54:00Z

←Older revision		Revision as of 06:54, 20 June 2018
Line 1:		Line 1:
		+
	==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==		==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==
	<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>		<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2go5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2go5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2go5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:14, 7 February 2016

2016-02-07T02:14:15Z

←Older revision		Revision as of 02:14, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2go5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:42, 9 September 2015

2015-09-09T20:42:21Z

←Older revision		Revision as of 20:42, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>		<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~], [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Human Human], [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://pdbe.org/2go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2go5" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Canis sp]]		[[Category: Canis sp]]
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Triticum sp]]		[[Category: Triticum sp]]
	[[Category: Beckmann, R]]		[[Category: Beckmann, R]]

OCA at 06:59, 24 December 2014

2014-12-24T06:59:28Z

←Older revision		Revision as of 06:59, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SRPRB_MOUSE SRPRB_MOUSE]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. [[http://www.uniprot.org/uniprot/SRP54_CANFA SRP54_CANFA]] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). [[http://www.uniprot.org/uniprot/SRPR_HUMAN SRPR_HUMAN]] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Canis sp.]]	+	[[Category: Canis sp]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Triticum sp.]]	+	[[Category: Triticum sp]]
-	[[Category: Beckmann, R.]]	+	[[Category: Beckmann, R]]
-	[[Category: Gartmann, M.]]	+	[[Category: Gartmann, M]]
-	[[Category: Halic, M.]]	+	[[Category: Halic, M]]
-	[[Category: Mielke, T.]]	+	[[Category: Mielke, T]]
-	[[Category: Pool, M R.]]	+	[[Category: Pool, M R]]
-	[[Category: Schlenker, O.]]	+	[[Category: Schlenker, O]]
-	[[Category: Sinning, I.]]	+	[[Category: Sinning, I]]
	[[Category: Ribosome]]		[[Category: Ribosome]]
	[[Category: Sr]]		[[Category: Sr]]
	[[Category: Srp]]		[[Category: Srp]]
	[[Category: Translation-rna complex]]		[[Category: Translation-rna complex]]

OCA at 02:16, 29 September 2014

2014-09-29T02:16:30Z

←Older revision		Revision as of 02:16, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2go5.~~png\|left~~\|200px]]	+	==Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex==
		+	<StructureSection load='2go5' size='340' side='right' caption='[[2go5]], [[Resolution\|resolution]] 7.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GO5 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2go5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2go5 RCSB], [http://www.ebi.ac.uk/pdbsum/2go5 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2go5_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Signal sequences of secretory and membrane proteins are recognized by the signal recognition particle (SRP) as they emerge from the ribosome. This results in their targeting to the membrane by docking with the SRP receptor, which facilitates transfer of the ribosome to the translocon. Here, we present the 8 angstrom cryo-electron microscopy structure of a "docking complex" consisting of a SRP-bound 80S ribosome and the SRP receptor. Interaction of the SRP receptor with both SRP and the ribosome rearranged the S domain of SRP such that a ribosomal binding site for the translocon, the L23e/L35 site, became exposed, whereas Alu domain-mediated elongation arrest persisted.

-	~~{{STRUCTURE_2go5\| PDB=2go5 \| SCENE= }}~~	+	Signal recognition particle receptor exposes the ribosomal translocon binding site.,Halic M, Gartmann M, Schlenker O, Mielke T, Pool MR, Sinning I, Beckmann R Science. 2006 May 5;312(5774):745-7. PMID:16675701<ref>PMID:16675701</ref>

-	~~===Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16675701}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2go5]] is a 9 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Canis_sp. Canis sp.]~~, ~~[http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens], [http://en~~.~~wikipedia.org~~/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA].	+

	==See Also==		==See Also==
-	*[[Ribosomal protein L23\|Ribosomal protein L23]]
	*[[Ribosomal protein L31\|Ribosomal protein L31]]		*[[Ribosomal protein L31\|Ribosomal protein L31]]
	*[[Ribosomal protein L35\|Ribosomal protein L35]]		*[[Ribosomal protein L35\|Ribosomal protein L35]]
	*[[Signal recognition particle protein\|Signal recognition particle protein]]		*[[Signal recognition particle protein\|Signal recognition particle protein]]
	*[[Signal recognition particle receptor\|Signal recognition particle receptor]]		*[[Signal recognition particle receptor\|Signal recognition particle receptor]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016675701<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Canis sp.]]		[[Category: Canis sp.]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]

OCA at 05:19, 20 October 2012

2012-10-20T05:19:01Z

←Older revision		Revision as of 05:19, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2go5]] is a 9 chain structure ~~of [[Ribosomal protein L23]], [[Ribosomal protein L31]], [[Ribosomal protein L35]], [[Signal recognition particle protein]] and [[Signal recognition particle receptor]]~~ with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA].	+	[[2go5]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_sp. Canis sp.], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Triticum_sp. Triticum sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GO5 OCA].

	==See Also==		==See Also==

OCA: Protected "2go5" [edit=sysop:move=sysop]

2012-07-25T09:39:44Z

Protected "2go5" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:39, 25 July 2012