2hkr - Revision history

OCA at 07:17, 24 March 2021

2021-03-24T07:17:26Z

←Older revision		Revision as of 07:17, 24 March 2021
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	==Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine==		==Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine==
-	<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='2hkr' size='340' side='right'caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Alcfa Alcfa] and [~~http~~://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HKR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcfa Alcfa] and [https://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HKR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hkm\|2hkm]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ALCFA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ALCFA])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase_(azurin) Aralkylamine dehydrogenase (azurin)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.9.2 1.4.9.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase_(azurin) Aralkylamine dehydrogenase (azurin)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.9.2 1.4.9.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [~~http~~://pdbe.org/2hkr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2hkr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hkr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [https://pdbe.org/2hkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [https://www.ebi.ac.uk/pdbsum/2hkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hkr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AAUA_ALCFA AAUA_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:7876189</ref> <ref>PMID:17087503</ref> <ref>PMID:17005560</ref> <ref>PMID:16614214</ref> [[~~http~~://www.uniprot.org/uniprot/AAUB_ALCFA AAUB_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:16614214</ref>	+	[[https://www.uniprot.org/uniprot/AAUA_ALCFA AAUA_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:7876189</ref> <ref>PMID:17087503</ref> <ref>PMID:17005560</ref> <ref>PMID:16614214</ref> [[https://www.uniprot.org/uniprot/AAUB_ALCFA AAUB_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:16614214</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 25:		Line 25:

	==See Also==		==See Also==
-	*[[Aromatic amine dehydrogenase\|Aromatic amine dehydrogenase]]	+	*[[Aromatic amine dehydrogenase 3D structures\|Aromatic amine dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 32:
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
	[[Category: Alcfa]]		[[Category: Alcfa]]
		+	[[Category: Large Structures]]
	[[Category: Leys, D]]		[[Category: Leys, D]]
	[[Category: Roujeinikova, A]]		[[Category: Roujeinikova, A]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 06:48, 27 June 2018

2018-06-27T06:48:18Z

←Older revision		Revision as of 06:48, 27 June 2018
Line 1:		Line 1:
		+
	==Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine==		==Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine==
	<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 8:		Line 9:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ALCFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ALCFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase_(azurin) Aralkylamine dehydrogenase (azurin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.9.2 1.4.9.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase_(azurin) Aralkylamine dehydrogenase (azurin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.9.2 1.4.9.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://pdbe.org/2hkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://pdbe.org/2hkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hkr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/2hkr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/2hkr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:26, 8 February 2016

2016-02-08T01:26:45Z

←Older revision		Revision as of 01:26, 8 February 2016
Line 20:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hkr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 06:35, 10 September 2015

2015-09-10T06:35:38Z

←Older revision		Revision as of 06:35, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HKR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcfa Alcfa] and [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HKR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ~~Alcaligenes faecalis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 ALCFA])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Aralkylamine_dehydrogenase~~ Aralkylamine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.99.4 1.4.99.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase_(azurin) Aralkylamine dehydrogenase (azurin)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.9.2 1.4.9.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://pdbe.org/2hkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AAUA_ALCFA AAUA_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:7876189</ref> <ref>PMID:17087503</ref> <ref>PMID:17005560</ref> <ref>PMID:16614214</ref> [[http://www.uniprot.org/uniprot/AAUB_ALCFA AAUB_ALCFA]] Oxidizes primary aromatic amines and, more slowly, some long-chain aliphatic amines, but not methylamine or ethylamine. Uses azurin as an electron acceptor to transfer electrons from the reduced tryptophylquinone cofactor.<ref>PMID:11495996</ref> <ref>PMID:16279953</ref> <ref>PMID:8188594</ref> <ref>PMID:16614214</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 25:
	==See Also==		==See Also==
	*[[Aromatic amine dehydrogenase\|Aromatic amine dehydrogenase]]		*[[Aromatic amine dehydrogenase\|Aromatic amine dehydrogenase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
-	[[Category: ~~Aralkylamine dehydrogenase~~]]	+	[[Category: Alcfa]]
	[[Category: Leys, D]]		[[Category: Leys, D]]
	[[Category: Roujeinikova, A]]		[[Category: Roujeinikova, A]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:23, 16 January 2015

2015-01-16T09:23:58Z

←Older revision		Revision as of 09:23, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HKR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HKR FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 Alcaligenes faecalis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 Alcaligenes faecalis])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase Aralkylamine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.99.4 1.4.99.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase Aralkylamine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.99.4 1.4.99.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
	[[Category: Aralkylamine dehydrogenase]]		[[Category: Aralkylamine dehydrogenase]]
-	[[Category: Leys, D.]]	+	[[Category: Leys, D]]
-	[[Category: Roujeinikova, A.]]	+	[[Category: Roujeinikova, A]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 10:51, 30 September 2014

2014-09-30T10:51:28Z

←Older revision		Revision as of 10:51, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2hkr.~~png~~\|~~left~~\|200px]]	+	==Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine==
		+	<StructureSection load='2hkr' size='340' side='right' caption='[[2hkr]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HKR FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZHH:2-(4-METHOXYPHENYL)ETHANAMINE'>ZHH</scene>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL)ACETAMIDE'>ZHZ</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRQ:2-AMINO-3-(6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL)-PROPIONIC+ACID'>TRQ</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2hkm\|2hkm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aauB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 Alcaligenes faecalis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase Aralkylamine dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.99.4 1.4.99.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/2hkr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

-	~~{{STRUCTURE_2hkr\| PDB~~=~~2hkr \| SCENE= }}~~	+	==See Also==
-		+	*[[Aromatic amine dehydrogenase\|Aromatic amine dehydrogenase]]
-	~~===Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine~~===	+	__TOC__
-		+	</StructureSection>
-		+
-	~~==About this Structure==~~	+
-	[[~~2hkr~~]] ~~is a 4 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA].~~	+
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
	[[Category: Aralkylamine dehydrogenase]]		[[Category: Aralkylamine dehydrogenase]]

OCA: Protected "2hkr" [edit=sysop:move=sysop]

2013-01-07T12:38:35Z

Protected "2hkr" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:38, 7 January 2013

OCA at 12:38, 7 January 2013

2013-01-07T12:38:32Z

←Older revision		Revision as of 12:38, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2hkr.png\|left\|200px]]		[[Image:2hkr.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2hkr", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2hkr\| PDB=2hkr \| SCENE= }}		{{STRUCTURE_2hkr\| PDB=2hkr \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~2HKR~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA].	+	[[2hkr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA].
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
	[[Category: Aralkylamine dehydrogenase]]		[[Category: Aralkylamine dehydrogenase]]
Line 20:		Line 13:
	[[Category: Roujeinikova, A.]]		[[Category: Roujeinikova, A.]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:48:37 2009''

OCA at 15:48, 16 February 2009

2009-02-16T15:48:39Z

←Older revision		Revision as of 15:48, 16 February 2009
Line 1:		Line 1:
-	[[Image:2hkr.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2hkr.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2hkr\| PDB=2hkr \| SCENE= }}		{{STRUCTURE_2hkr\| PDB=2hkr \| SCENE= }}

-	~~'''~~Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine~~'''~~	+	===Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine===


	==About this Structure==		==About this Structure==
-	2HKR is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA].	+	2HKR is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HKR OCA].
	[[Category: Alcaligenes faecalis]]		[[Category: Alcaligenes faecalis]]
	[[Category: Aralkylamine dehydrogenase]]		[[Category: Aralkylamine dehydrogenase]]
-	[[Category: Protein complex]]
	[[Category: Leys, D.]]		[[Category: Leys, D.]]
	[[Category: Roujeinikova, A.]]		[[Category: Roujeinikova, A.]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 06~~:24:~~26 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:48:37 2009''

OCA at 03:24, 4 May 2008

2008-05-04T03:24:26Z

←Older revision		Revision as of 03:24, 4 May 2008
Line 1:		Line 1:
	[[Image:2hkr.jpg\|left\|200px]]		[[Image:2hkr.jpg\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 2hkr \|SIZE=350\|CAPTION= <scene name='initialview01'>2hkr</scene>~~, ~~resolution 1~~.~~400Å~~	+	The line below this paragraph, containing "STRUCTURE_2hkr", creates the "Structure Box" on the page.
-	~~\|SITE= <scene name='pdbsite=AC1:Zhz+Binding+Site+For+Residue+H+1501'>AC1</scene> and <scene name='pdbsite=AC2:Zhh+Binding+Site+For+Residue+D+1502'>AC2</scene>~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=TRQ:2-AMINO-3-~~(~~6,7-DIOXO-6,7-DIHYDRO-1H-INDOL-3-YL~~)~~-PROPIONIC+ACID'>TRQ</scene>, <scene name='pdbligand=ZHH:2-~~(~~4-METHOXYPHENYL)ETHANAMINE'>ZHH</~~scene~~>, <scene name='pdbligand=ZHZ:2-(4-METHOXYPHENYL~~)~~ACETAMIDE'>ZHZ</scene>~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Aralkylamine_dehydrogenase Aralkylamine dehydrogenase]~~, ~~with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.99.4 1.4.99.4] </span>~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE= aauB ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=511 Alcaligenes faecalis])~~	+	-->
-	~~\|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02975 Me~~-~~amine~~-~~dh_L], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam06433 Me-amine-dh_H]</span~~>	+	{{STRUCTURE_2hkr\| PDB=2hkr \| SCENE= }}
-	\|~~RELATEDENTRY~~=~~[[2hkm~~\|~~2HKM]]~~	+
-	~~\|RESOURCES~~=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hkr OCA], [http://www.ebi.ac.uk/pdbsum/2hkr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hkr RCSB]</span>	+
-	}}	+

	'''Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine'''		'''Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine'''
Line 22:		Line 19:
	[[Category: Leys, D.]]		[[Category: Leys, D.]]
	[[Category: Roujeinikova, A.]]		[[Category: Roujeinikova, A.]]
-	[[Category: ~~oxidoreductase~~]]	+	[[Category: Oxidoreductase]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:24:26 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Apr~~ ~~2 11~~:57:16 2008''	+