2ho0 - Revision history

OCA at 09:59, 30 August 2023

2023-08-30T09:59:52Z

←Older revision		Revision as of 09:59, 30 August 2023
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	<StructureSection load='2ho0' size='340' side='right'caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ho0' size='340' side='right'caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [https://pdbe.org/2ho0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ho0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ho0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [https://pdbe.org/2ho0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ho0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ho0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7B004_ECOLX Q7B004_ECOLX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bell~~, C E~~]]	+	[[Category: Bell CE]]
-	[[Category: Ndjonka, D]]	+	[[Category: Ndjonka D]]
-	~~[[Category: Viral protein~~]]	+

OCA at 17:44, 20 October 2021

2021-10-20T17:44:57Z

←Older revision		Revision as of 17:44, 20 October 2021
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	<StructureSection load='2ho0' size='340' side='right'caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ho0' size='340' side='right'caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [~~http~~://pdbe.org/2ho0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ho0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ho0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [https://pdbe.org/2ho0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ho0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ho0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2ho0" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2ho0" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Bacteriophage repressor 3D structures\|Bacteriophage repressor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:12, 1 April 2020

2020-04-01T10:12:58Z

←Older revision		Revision as of 10:12, 1 April 2020
Line 1:		Line 1:

	==Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region==		==Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region==
-	<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2ho0' size='340' side='right'caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Bacteriophage repressor\|Bacteriophage repressor]]	+	*[[Bacteriophage repressor 3D structures\|Bacteriophage repressor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Bell, C E]]		[[Category: Bell, C E]]
	[[Category: Ndjonka, D]]		[[Category: Ndjonka, D]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 06:09, 27 June 2018

2018-06-27T06:09:09Z

←Older revision		Revision as of 06:09, 27 June 2018
Line 1:		Line 1:
		+
	==Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region==		==Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region==
	<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://pdbe.org/2ho0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://pdbe.org/2ho0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ho0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/2ho0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/2ho0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ho0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:16, 11 September 2015

2015-09-11T17:16:54Z

←Older revision		Revision as of 17:16, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://pdbe.org/2ho0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ho0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Bell, C E]]		[[Category: Bell, C E]]
	[[Category: Ndjonka, D]]		[[Category: Ndjonka, D]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 08:47, 16 January 2015

2015-01-16T08:47:39Z

←Older revision		Revision as of 08:47, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Bell, C E.]]	+	[[Category: Bell, C E]]
-	[[Category: Ndjonka, D.]]	+	[[Category: Ndjonka, D]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 08:24, 30 September 2014

2014-09-30T08:24:47Z

←Older revision		Revision as of 08:24, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2ho0.~~png~~\|~~left~~\|200px]]	+	==Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region==
		+	<StructureSection load='2ho0' size='340' side='right' caption='[[2ho0]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HO0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f39\|1f39]], [[1jhc\|1jhc]], [[1jhe\|1jhe]], [[2hnf\|2hnf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ho0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ho0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ho0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ho0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/2ho0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The key event in the switch from lysogenic to lytic growth of phage lambda is the self-cleavage of lambda repressor, which is induced by the formation of a RecA-ssDNA-ATP filament at a site of DNA damage. Lambda repressor cleaves itself at the peptide bond between Ala111 and Gly112, but only when bound as a monomer to the RecA-ssDNA-ATP filament. Here we have designed a hyper-cleavable fragment of lambda repressor containing the hinge and C-terminal domain (residues 101-229), in which the monomer-monomer interface is disrupted by two point mutations and a deletion of seven residues at the C terminus. This fragment crystallizes as a monomer and its structure has been determined to 1.8 A resolution. The hinge region, which bears the cleavage site, is folded over the active site of the C-terminal oligomerization domain (CTD) but with the cleavage site flipped out and exposed to solvent. Thus, the structure represents a non-cleavable conformation of the repressor, but one that is poised for cleavage after modest rearrangements that are presumably stabilized by binding to RecA. The structure provides a unique snapshot of lambda repressor in a conformation that sheds light on how its self-cleavage is tempered in the absence of RecA, as well as a framework for interpreting previous genetic and biochemical data concerning the RecA-mediated cleavage reaction.

-	~~{{STRUCTURE_2ho0\| PDB=2ho0 \| SCENE= }}~~	+	Structure of a hyper-cleavable monomeric fragment of phage lambda repressor containing the cleavage site region.,Ndjonka D, Bell CE J Mol Biol. 2006 Sep 22;362(3):479-89. Epub 2006 Jul 15. PMID:16934834<ref>PMID:16934834</ref>

-	~~===Structure of~~ a ~~Hyper-cleavable Monomeric Fragment~~ of ~~Phage Lambda Repressor Containing~~ the ~~Cleavage Site Region===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_16934834}}~~	+	==See Also==
-		+	*[[Bacteriophage repressor\|Bacteriophage repressor]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~2ho0~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:016934834<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bell, C E.]]		[[Category: Bell, C E.]]
	[[Category: Ndjonka, D.]]		[[Category: Ndjonka, D.]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA: Protected "2ho0" [edit=sysop:move=sysop]

2013-01-07T10:49:28Z

Protected "2ho0" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:49, 7 January 2013

OCA at 10:49, 7 January 2013

2013-01-07T10:49:24Z

←Older revision		Revision as of 10:49, 7 January 2013
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-	{{Seed}}
	[[Image:2ho0.png\|left\|200px]]		[[Image:2ho0.png\|left\|200px]]

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	{{STRUCTURE_2ho0\| PDB=2ho0 \| SCENE= }}		{{STRUCTURE_2ho0\| PDB=2ho0 \| SCENE= }}

	===Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region===		===Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16934834}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16934834 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16934834}}		{{ABSTRACT_PUBMED_16934834}}

	==About this Structure==		==About this Structure==
-	~~2HO0~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA].	+	[[2ho0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16934834~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016934834</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bell, C E.]]		[[Category: Bell, C E.]]
	[[Category: Ndjonka, D.]]		[[Category: Ndjonka, D.]]
-	[[Category: ~~Virus/viral~~ protein]]	+	[[Category: Viral protein]]
-		+
-	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:32:54 2009''~~	+

OCA at 02:32, 18 February 2009

2009-02-18T02:32:56Z

←Older revision		Revision as of 02:32, 18 February 2009
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	==About this Structure==		==About this Structure==
-	2HO0 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA].	+	2HO0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HO0 OCA].

	==Reference==		==Reference==
-	~~Structure of a hyper-cleavable monomeric fragment of phage lambda repressor containing the cleavage site region., Ndjonka D, Bell CE, J Mol Biol. 2006 Sep 22;362(3):479-89. Epub 2006 Jul 15.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16934834 16934834]~~	+	<ref group="xtra">PMID:16934834</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Bell, C E.]]		[[Category: Bell, C E.]]
	[[Category: Ndjonka, D.]]		[[Category: Ndjonka, D.]]
	[[Category: Virus/viral protein]]		[[Category: Virus/viral protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 11~~:21:~~02 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:32:54 2009''