2hx7 - Revision history

OCA at 10:02, 30 August 2023

2023-08-30T10:02:59Z

←Older revision		Revision as of 10:02, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2hx7' size='340' side='right'caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2hx7' size='340' side='right'caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[2fta\|2fta]]~~, [[~~2ft6~~\|~~2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>azu ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~287~~ "~~Bacillus aeruginosus~~" (~~Schroeter 1872) Trevisan 1885]~~)</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [https://pdbe.org/2hx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2hx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hx7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [https://pdbe.org/2hx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2hx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hx7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.	+	[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2hx7" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2hx7" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Azurin 3D structures\|Azurin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Banfield, M J~~]]	+	[[Category: Pseudomonas aeruginosa]]
-	[[Category: ~~Blue copper-binding protein]]~~	+	[[Category: Banfield MJ]]
-	~~[[Category: Electron transport]]~~	+
-	~~[[Category: Greek-key beta-barrel]]~~	+
-	~~[[Category: Loop mutagenesis~~]]	+

OCA at 07:23, 24 March 2021

2021-03-24T07:23:41Z

←Older revision		Revision as of 07:23, 24 March 2021
Line 1:		Line 1:

	==Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"==		==Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"==
-	<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='2hx7' size='340' side='right'caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [~~http~~://pdbe.org/2hx7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2hx7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hx7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [https://pdbe.org/2hx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2hx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hx7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.	+	[[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 2hx7" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2hx7" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Azurin\|Azurin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]

OCA at 08:27, 4 July 2018

2018-07-04T08:27:34Z

←Older revision		Revision as of 08:27, 4 July 2018
Line 1:		Line 1:
		+
	==Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"==		==Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"==
	<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://pdbe.org/2hx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://pdbe.org/2hx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hx7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hx7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hx7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:13, 7 February 2016

2016-02-07T03:13:47Z

←Older revision		Revision as of 03:13, 7 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hx7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:07, 9 September 2015

2015-09-09T21:07:47Z

←Older revision		Revision as of 21:07, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 ~~Pseudomonas aeruginosa~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://pdbe.org/2hx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2hx7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]

OCA at 07:24, 24 December 2014

2014-12-24T07:24:14Z

←Older revision		Revision as of 07:24, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Banfield, M J.]]	+	[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]
	[[Category: Greek-key beta-barrel]]		[[Category: Greek-key beta-barrel]]
	[[Category: Loop mutagenesis]]		[[Category: Loop mutagenesis]]

OCA at 08:11, 30 September 2014

2014-09-30T08:11:41Z

←Older revision		Revision as of 08:11, 30 September 2014
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-	[[~~Image:~~2hx7.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"==
		+	<StructureSection load='2hx7' size='340' side='right' caption='[[2hx7]], [[Resolution\|resolution]] 1.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HX7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2hx7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hx7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ligand-containing loops of two copper-binding electron-transfer proteins (cupredoxins) have been swapped. In the azurin (AZ) variant in which the plastocyanin (PC) sequence is introduced (AZPC), the loop adopts a conformation identical to that in PC. The reduction potential of AZPC is raised as compared to AZ and matches that of PC. In the previously published AZAMI variant (AMI = amicyanin), the shorter introduced loop adopts the same conformation as in AMI, and the reduction potential is lowered to equal that of AMI (Yanagisawa, S.; Dennison, C. J. Am. Chem. Soc. 2004, 126, 15711-15719. Li, C.; et al. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 7258-7263). Thus, the loop structure plays an important role in tuning the reduction potential of a type 1 copper site with contributions from protein dipoles in this region probably the most important feature. The structure of the loop also seems to be a major factor in controlling dissociation and protonation of the C-terminal His ligand, which can act as a switch to regulate electron-transfer reactivity. The PCAZ variant (PC with the AZ loop) possesses an active site, which is different from those of both PC and AZ, and it is assumed that the introduced loop does not adopt a structure as in AZ. This contributes to the observed instability of PCAZ and highlights that loop-scaffold interactions are important for stabilizing the active site of a cupredoxin.

-	~~{{STRUCTURE_2hx7\| PDB=2hx7 \| SCENE= }}~~	+	Engineering copper sites in proteins: loops confer native structures and properties to chimeric cupredoxins.,Li C, Banfield MJ, Dennison C J Am Chem Soc. 2007 Jan 24;129(3):709-18. PMID:17227035<ref>PMID:17227035</ref>

-	~~===Crystal structure~~ of ~~Cu(II) Azurin with~~ the ~~metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_17227035}}~~	+	==See Also==
-		+	*[[Azurin\|Azurin]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~2hx7~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:017227035<~~/~~ref~~><~~ref group="xtra">PMID:016651527</ref><references group="xtra"~~/>	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]

OCA at 13:07, 30 January 2013

2013-01-30T13:07:24Z

←Older revision		Revision as of 13:07, 30 January 2013
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	[[Image:2hx7.png\|left\|200px]]		[[Image:2hx7.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2hx7\| PDB=2hx7 \| SCENE= }}		{{STRUCTURE_2hx7\| PDB=2hx7 \| SCENE= }}

	===Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"===		===Crystal structure of Cu(II) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM"===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17227035}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17227035 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17227035}}		{{ABSTRACT_PUBMED_17227035}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17227035~~</ref><ref group="xtra">PMID:~~16651527~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017227035</ref><ref group="xtra">PMID:016651527</ref><references group="xtra"/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]

OCA: Protected "2hx7" [edit=sysop:move=sysop]

2011-03-14T19:01:39Z

Protected "2hx7" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:01, 14 March 2011

OCA at 19:01, 14 March 2011

2011-03-14T19:01:37Z

←Older revision		Revision as of 19:01, 14 March 2011
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-	{{Seed}}
	[[Image:2hx7.png\|left\|200px]]		[[Image:2hx7.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2HX7~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA].	+	[[2hx7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HX7 OCA].

	==Reference==		==Reference==
Line 27:		Line 26:
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]
		+	[[Category: Electron transport]]
	[[Category: Greek-key beta-barrel]]		[[Category: Greek-key beta-barrel]]
	[[Category: Loop mutagenesis]]		[[Category: Loop mutagenesis]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:41:22 2009''