2igg - Revision history

OCA at 19:04, 29 May 2024

2024-05-29T19:04:08Z

←Older revision		Revision as of 19:04, 29 May 2024
Line 1:		Line 1:

	==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==		==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==
-	<StructureSection load='2igg' size='340' side='right'caption='[[2igg~~]], [[NMR_Ensembles_of_Models \| 27 NMR models~~]]' scene=''>	+	<StructureSection load='2igg' size='340' side='right'caption='[[2igg]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Streptococcus_gx7809~~ Streptococcus ~~gx7809~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IGG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sp._GX7805 Streptococcus sp. GX7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [https://pdbe.org/2igg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [https://www.ebi.ac.uk/pdbsum/2igg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [https://pdbe.org/2igg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [https://www.ebi.ac.uk/pdbsum/2igg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SPG2_STRSG SPG2_STRSG]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Streptococcus ~~gx7809~~]]	+	[[Category: Streptococcus sp. GX7805]]
-	[[Category: Derrick~~, J P~~]]	+	[[Category: Derrick JP]]
-	[[Category: Lian, L Y]]	+	[[Category: Lian L-Y]]
-	[[Category: Roberts~~, G C.K~~]]	+	[[Category: Roberts GCK]]
-	[[Category: Sutcliffe~~, M J~~]]	+	[[Category: Sutcliffe MJ]]
-	[[Category: Yang~~, J C]]~~	+	[[Category: Yang JC]]
-	~~[[Category: Immunoglobulin-binding protein~~]]	+

OCA at 10:27, 12 January 2022

2022-01-12T10:27:19Z

←Older revision		Revision as of 10:27, 12 January 2022
Line 3:		Line 3:
	<StructureSection load='2igg' size='340' side='right'caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>		<StructureSection load='2igg' size='340' side='right'caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IGG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [~~http~~://pdbe.org/2igg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2igg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [https://pdbe.org/2igg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [https://www.ebi.ac.uk/pdbsum/2igg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:45, 8 April 2020

2020-04-08T07:45:34Z

←Older revision		Revision as of 07:45, 8 April 2020
Line 1:		Line 1:

	==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==		==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==
-	<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>	+	<StructureSection load='2igg' size='340' side='right'caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IGG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://pdbe.org/2igg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://pdbe.org/2igg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Streptococcus gx7809]]		[[Category: Streptococcus gx7809]]
	[[Category: Derrick, J P]]		[[Category: Derrick, J P]]

OCA at 08:39, 4 July 2018

2018-07-04T08:39:53Z

←Older revision		Revision as of 08:39, 4 July 2018
Line 1:		Line 1:
		+
	==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==		==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==
	<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>		<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://pdbe.org/2igg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://pdbe.org/2igg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2igg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2igg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2igg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:55, 8 February 2016

2016-02-08T06:55:26Z

←Older revision		Revision as of 06:55, 8 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2igg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:01, 10 September 2015

2015-09-10T09:01:04Z

←Older revision		Revision as of 09:01, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>		<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_sp._gx7805~~ Streptococcus ~~sp. gx7805~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_gx7809 Streptococcus gx7809]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://pdbe.org/2igg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2igg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptococcus ~~sp. gx7805~~]]	+	[[Category: Streptococcus gx7809]]
	[[Category: Derrick, J P]]		[[Category: Derrick, J P]]
	[[Category: Lian, L Y]]		[[Category: Lian, L Y]]

OCA at 08:45, 16 January 2015

2015-01-16T08:45:15Z

←Older revision		Revision as of 08:45, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Protein G\|Protein G]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Streptococcus sp. gx7805]]		[[Category: Streptococcus sp. gx7805]]
-	[[Category: Derrick, J P.]]	+	[[Category: Derrick, J P]]
-	[[Category: Lian, L Y.]]	+	[[Category: Lian, L Y]]
-	[[Category: Roberts, G C.K.]]	+	[[Category: Roberts, G C.K]]
-	[[Category: Sutcliffe, M J.]]	+	[[Category: Sutcliffe, M J]]
-	[[Category: Yang, J C.]]	+	[[Category: Yang, J C]]
	[[Category: Immunoglobulin-binding protein]]		[[Category: Immunoglobulin-binding protein]]

OCA at 10:18, 30 September 2014

2014-09-30T10:18:29Z

←Older revision		Revision as of 10:18, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2igg.~~png\|left~~\|200px]]	+	==DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR==
		+	<StructureSection load='2igg' size='340' side='right' caption='[[2igg]], [[NMR_Ensembles_of_Models \| 27 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2igg RCSB], [http://www.ebi.ac.uk/pdbsum/2igg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/2igg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have used 1H nuclear magnetic resonance spectroscopy to determine the solution structures of two small (61 and 64 residue) immunoglobulin G (IgG)-binding domains from protein G, a cell-surface protein from Streptococcus strain G148. The two domains differ in sequence by four amino acid substitutions, and differ in their affinity for some subclasses of IgG. The structure of domain II was determined using a total of 478 distance restraints, 31 phi and 9 chi 1 dihedral angle restraints; that of domain III was determined using a total of 445 distance restraints, 31 phi and 9 chi 1 dihedral angle restraints. A protocol which involved distance geometry, simulated annealing and restrained molecular dynamics was used to determine ensembles of 40 structures consistent with these restraints. The structures are found to consist of an alpha-helix packed against a four-stranded antiparallel-parallel-antiparallel beta-sheet. The structures of the two domains are compared to each other and to the reported structure of a similar domain from a protein G from a different strain of Streptococcus. We conclude that the difference in affinity of domains II and III for IgG is due to local changes in amino acid side-chains, rather than a more extensive change in conformation, suggesting that one or more of the residues which differ between them are directly involved in interaction with IgG.

-	~~{{STRUCTURE_2igg\| PDB=2igg \| SCENE= }}~~	+	Determination of the solution structures of domains II and III of protein G from Streptococcus by 1H nuclear magnetic resonance.,Lian LY, Derrick JP, Sutcliffe MJ, Yang JC, Roberts GC J Mol Biol. 1992 Dec 20;228(4):1219-34. PMID:1474588<ref>PMID:1474588</ref>

-	~~===DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_1474588}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2igg]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_sp~~.~~_gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:001474588<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Streptococcus sp. gx7805]]		[[Category: Streptococcus sp. gx7805]]
	[[Category: Derrick, J P.]]		[[Category: Derrick, J P.]]

OCA: Protected "2igg" [edit=sysop:move=sysop]

2013-01-07T14:45:46Z

Protected "2igg" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:45, 7 January 2013

OCA at 14:45, 7 January 2013

2013-01-07T14:45:42Z

←Older revision		Revision as of 14:45, 7 January 2013
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-	{{Seed}}
	[[Image:2igg.png\|left\|200px]]		[[Image:2igg.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2igg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2igg\| PDB=2igg \| SCENE= }}		{{STRUCTURE_2igg\| PDB=2igg \| SCENE= }}

	===DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR===		===DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_1474588}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 1474588 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_1474588}}		{{ABSTRACT_PUBMED_1474588}}

	==About this Structure==		==About this Structure==
-	~~2IGG~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA].	+	[[2igg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._gx7805 Streptococcus sp. gx7805]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGG OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~1474588~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:001474588</ref><references group="xtra"/>
	[[Category: Streptococcus sp. gx7805]]		[[Category: Streptococcus sp. gx7805]]
	[[Category: Derrick, J P.]]		[[Category: Derrick, J P.]]
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	[[Category: Yang, J C.]]		[[Category: Yang, J C.]]
	[[Category: Immunoglobulin-binding protein]]		[[Category: Immunoglobulin-binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:59:12 2009''