2ive - Revision history

OCA at 14:26, 13 December 2023

2023-12-13T14:26:33Z

←Older revision		Revision as of 14:26, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2ive' size='340' side='right'caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2ive' size='340' side='right'caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_25232 Atcc 25232~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ivd\|2ivd]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [https://pdbe.org/2ive PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [https://www.ebi.ac.uk/pdbsum/2ive PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [https://pdbe.org/2ive PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [https://www.ebi.ac.uk/pdbsum/2ive PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PGOX_MYXXA PGOX_MYXXA] Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX (PubMed:8621504). Does not oxidize coproporphyrinogen III (PubMed:8621504). Involved in the classical protoporphyrin-dependent (PPD) heme b biosynthesis (PubMed:28123057).<ref>PMID:8621504</ref> <ref>PMID:28123057</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 25232]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Acharya~~, K R~~]]	+	[[Category: Myxococcus xanthus]]
-	[[Category: Boix, E]]	+	[[Category: Acharya KR]]
-	[[Category: Corradi~~, H R~~]]	+	[[Category: Boix E]]
-	[[Category: Corrigall~~, A V~~]]	+	[[Category: Corradi HR]]
-	[[Category: Meissner~~, P N~~]]	+	[[Category: Corrigall AV]]
-	[[Category: Mohan~~, C G~~]]	+	[[Category: Meissner PN]]
-	[[Category: Sturrock~~, E D]]~~	+	[[Category: Mohan CG]]
-	~~[[Category: Chlorophyll biosynthesis]]~~	+	[[Category: Sturrock ED]]
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Haem biosynthesis]]~~	+
-	~~[[Category: Heme biosynthesis]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Porphyria]]~~	+
-	~~[[Category: Porphyrin biosynthesis]]~~	+
-	~~[[Category: Protoporphyrinogen oxidase~~]]	+

OCA at 10:33, 12 January 2022

2022-01-12T10:33:24Z

←Older revision		Revision as of 10:33, 12 January 2022
Line 3:		Line 3:
	<StructureSection load='2ive' size='340' side='right'caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2ive' size='340' side='right'caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_25232 Atcc 25232]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_25232 Atcc 25232]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ivd\|2ivd]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [~~http~~://pdbe.org/2ive PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ive PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [https://pdbe.org/2ive PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [https://www.ebi.ac.uk/pdbsum/2ive PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:52, 8 April 2020

2020-04-08T07:52:11Z

←Older revision		Revision as of 07:52, 8 April 2020
Line 1:		Line 1:

	==Structure of protoporphyrinogen oxidase from Myxococcus xanthus==		==Structure of protoporphyrinogen oxidase from Myxococcus xanthus==
-	<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='2ive' size='340' side='right'caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25232 Atcc 25232]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25232 Atcc 25232]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://pdbe.org/2ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://pdbe.org/2ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 25232]]		[[Category: Atcc 25232]]
		+	[[Category: Large Structures]]
	[[Category: Acharya, K R]]		[[Category: Acharya, K R]]
	[[Category: Boix, E]]		[[Category: Boix, E]]

OCA at 08:32, 4 July 2018

2018-07-04T08:32:07Z

←Older revision		Revision as of 08:32, 4 July 2018
Line 1:		Line 1:
-	==~~STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS~~==	+
		+	==Structure of protoporphyrinogen oxidase from Myxococcus xanthus==
	<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://pdbe.org/2ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://pdbe.org/2ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ive ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ive_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ive_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 00:26, 10 February 2016

2016-02-10T00:26:13Z

←Older revision		Revision as of 00:26, 10 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ive ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:32, 11 September 2015

2015-09-11T03:32:43Z

←Older revision		Revision as of 03:32, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Myxococcus_xanthus Myxococcus xanthus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25232 Atcc 25232]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://pdbe.org/2ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ive" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Myxococcus xanthus~~]]	+	[[Category: Atcc 25232]]
	[[Category: Acharya, K R]]		[[Category: Acharya, K R]]
	[[Category: Boix, E]]		[[Category: Boix, E]]

OCA at 17:02, 19 January 2015

2015-01-19T17:02:38Z

←Older revision		Revision as of 17:02, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Myxococcus xanthus]]		[[Category: Myxococcus xanthus]]
-	[[Category: Acharya, K R.]]	+	[[Category: Acharya, K R]]
-	[[Category: Boix, E.]]	+	[[Category: Boix, E]]
-	[[Category: Corradi, H R.]]	+	[[Category: Corradi, H R]]
-	[[Category: Corrigall, A V.]]	+	[[Category: Corrigall, A V]]
-	[[Category: Meissner, P N.]]	+	[[Category: Meissner, P N]]
-	[[Category: Mohan, C G.]]	+	[[Category: Mohan, C G]]
-	[[Category: Sturrock, E D.]]	+	[[Category: Sturrock, E D]]
	[[Category: Chlorophyll biosynthesis]]		[[Category: Chlorophyll biosynthesis]]
	[[Category: Fad]]		[[Category: Fad]]

OCA at 10:10, 30 September 2014

2014-09-30T10:10:06Z

←Older revision		Revision as of 10:10, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2ive.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS==
		+	<StructureSection load='2ive' size='340' side='right' caption='[[2ive]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVE FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWN:(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL+LAURATE'>TWN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ivd\|2ivd]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ive OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ive RCSB], [http://www.ebi.ac.uk/pdbsum/2ive PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ive_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protoporphyrinogen IX oxidase, a monotopic membrane protein, which catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX in the heme/chlorophyll biosynthetic pathway, is distributed widely throughout nature. Here we present the structure of protoporphyrinogen IX oxidase from Myxococcus xanthus, an enzyme with similar catalytic properties to human protoporphyrinogen IX oxidase that also binds the common plant herbicide, acifluorfen. In the native structure, the planar porphyrinogen substrate is mimicked by a Tween 20 molecule, tracing three sides of the macrocycle. In contrast, acifluorfen does not mimic the planarity of the substrate but is accommodated by the shape of the binding pocket and held in place by electrostatic and aromatic interactions. A hydrophobic patch surrounded by positively charged residues suggests the position of the membrane anchor, differing from the one proposed for the tobacco mitochondrial protoporphyrinogen oxidase. Interestingly, there is a discrepancy between the dimerization state of the protein in solution and in the crystal. Conserved structural features are discussed in relation to a number of South African variegate porphyria-causing mutations in the human enzyme.

-	~~{{STRUCTURE_2ive\| PDB=2ive \| SCENE= }}~~	+	Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen.,Corradi HR, Corrigall AV, Boix E, Mohan CG, Sturrock ED, Meissner PN, Acharya KR J Biol Chem. 2006 Dec 15;281(50):38625-33. Epub 2006 Oct 17. PMID:17046834<ref>PMID:17046834</ref>

-	~~===STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17046834}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2ive]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Myxococcus_xanthus Myxococcus xanthus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017046834<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Myxococcus xanthus]]		[[Category: Myxococcus xanthus]]
	[[Category: Acharya, K R.]]		[[Category: Acharya, K R.]]

OCA: Protected "2ive" [edit=sysop:move=sysop]

2013-01-07T14:38:52Z

Protected "2ive" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:38, 7 January 2013

OCA at 14:38, 7 January 2013

2013-01-07T14:38:48Z

←Older revision		Revision as of 14:38, 7 January 2013
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-	{{Seed}}
	[[Image:2ive.png\|left\|200px]]		[[Image:2ive.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2ive\| PDB=2ive \| SCENE= }}		{{STRUCTURE_2ive\| PDB=2ive \| SCENE= }}

	===STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS===		===STRUCTURE OF PROTOPORPHYRINOGEN OXIDASE FROM MYXOCOCCUS XANTHUS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17046834}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17046834 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17046834}}		{{ABSTRACT_PUBMED_17046834}}

	==About this Structure==		==About this Structure==
-	~~2IVE~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA].	+	[[2ive]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17046834~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017046834</ref><references group="xtra"/>
	[[Category: Myxococcus xanthus]]		[[Category: Myxococcus xanthus]]
	[[Category: Acharya, K R.]]		[[Category: Acharya, K R.]]
Line 41:		Line 29:
	[[Category: Porphyrin biosynthesis]]		[[Category: Porphyrin biosynthesis]]
	[[Category: Protoporphyrinogen oxidase]]		[[Category: Protoporphyrinogen oxidase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:56:49 2009''