2iwh - Revision history

OCA at 09:30, 9 May 2024

2024-05-09T09:30:56Z

←Older revision		Revision as of 09:30, 9 May 2024
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	<StructureSection load='2iwh' size='340' side='right'caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2iwh' size='340' side='right'caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID~~-~~ADENYLATE+ESTER'>ANP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2iw3\|2iw3]]~~, ~~[[2ix3\|2ix3]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [https://pdbe.org/2iwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [https://www.ebi.ac.uk/pdbsum/2iwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [https://pdbe.org/2iwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [https://www.ebi.ac.uk/pdbsum/2iwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Anand, M]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Andersen~~, C B.F~~]]	+	[[Category: Anand M]]
-	[[Category: Andersen~~, G R~~]]	+	[[Category: Andersen CBF]]
-	[[Category: Balar, B]]	+	[[Category: Andersen GR]]
-	[[Category: Becker, T]]	+	[[Category: Balar B]]
-	[[Category: Beckmann, R]]	+	[[Category: Becker T]]
-	[[Category: Blau, M]]	+	[[Category: Beckmann R]]
-	[[Category: Boesen, T]]	+	[[Category: Blau M]]
-	[[Category: Halic, M]]	+	[[Category: Boesen T]]
-	[[Category: Kinzy~~, T G~~]]	+	[[Category: Halic M]]
-	[[Category: Mielke, T]]	+	[[Category: Kinzy TG]]
-	[[Category: Pedersen~~, J S~~]]	+	[[Category: Mielke T]]
-	[[Category: Spahn~~, C M.T]]~~	+	[[Category: Pedersen JS]]
-	~~[[Category: Acetylation]]~~	+	[[Category: Spahn CMT]]
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Elongation factor]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Phosphorylation]]~~	+
-	~~[[Category: Protein biosynthesis]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rrna-binding]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 10:05, 12 May 2021

2021-05-12T10:05:44Z

←Older revision		Revision as of 10:05, 12 May 2021
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	<StructureSection load='2iwh' size='340' side='right'caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2iwh' size='340' side='right'caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2iw3\|2iw3]], [[2ix3\|2ix3]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [~~http~~://pdbe.org/2iwh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2iwh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [https://pdbe.org/2iwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [https://www.ebi.ac.uk/pdbsum/2iwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:20, 24 July 2019

2019-07-24T07:20:55Z

←Older revision		Revision as of 07:20, 24 July 2019
Line 1:		Line 1:

	==Structure of yeast Elongation Factor 3 in complex with ADPNP==		==Structure of yeast Elongation Factor 3 in complex with ADPNP==
-	<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='2iwh' size='340' side='right'caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Elongation factor\|Elongation factor]]	+	*[[Elongation factor 3D structures\|Elongation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Anand, M]]		[[Category: Anand, M]]
	[[Category: Andersen, C B.F]]		[[Category: Andersen, C B.F]]

OCA at 08:17, 4 July 2018

2018-07-04T08:17:49Z

←Older revision		Revision as of 08:17, 4 July 2018
Line 1:		Line 1:
-	==~~STRUCTURE OF YEAST ELONGATION FACTOR~~ 3 ~~IN COMPLEX WITH~~ ADPNP==	+
		+	==Structure of yeast Elongation Factor 3 in complex with ADPNP==
	<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://pdbe.org/2iwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://pdbe.org/2iwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iwh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iwh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 47:		Line 48:
	[[Category: Pedersen, J S]]		[[Category: Pedersen, J S]]
	[[Category: Spahn, C M.T]]		[[Category: Spahn, C M.T]]
		+	[[Category: Acetylation]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Elongation factor]]		[[Category: Elongation factor]]

OCA at 11:34, 8 February 2016

2016-02-08T11:34:31Z

←Older revision		Revision as of 11:34, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iwh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:09, 10 September 2015

2015-09-10T11:09:02Z

←Older revision		Revision as of 11:09, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://pdbe.org/2iwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2iwh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Anand, M]]		[[Category: Anand, M]]
	[[Category: Andersen, C B.F]]		[[Category: Andersen, C B.F]]

OCA at 15:37, 19 January 2015

2015-01-19T15:37:49Z

←Older revision		Revision as of 15:37, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Anand, M.]]	+	[[Category: Anand, M]]
-	[[Category: Andersen, C B.F.]]	+	[[Category: Andersen, C B.F]]
-	[[Category: Andersen, G R.]]	+	[[Category: Andersen, G R]]
-	[[Category: Balar, B.]]	+	[[Category: Balar, B]]
-	[[Category: Becker, T.]]	+	[[Category: Becker, T]]
-	[[Category: Beckmann, R.]]	+	[[Category: Beckmann, R]]
-	[[Category: Blau, M.]]	+	[[Category: Blau, M]]
-	[[Category: Boesen, T.]]	+	[[Category: Boesen, T]]
-	[[Category: Halic, M.]]	+	[[Category: Halic, M]]
-	[[Category: Kinzy, T G.]]	+	[[Category: Kinzy, T G]]
-	[[Category: Mielke, T.]]	+	[[Category: Mielke, T]]
-	[[Category: Pedersen, J S.]]	+	[[Category: Pedersen, J S]]
-	[[Category: Spahn, C M.T.]]	+	[[Category: Spahn, C M.T]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Elongation factor]]		[[Category: Elongation factor]]

OCA at 03:02, 29 September 2014

2014-09-29T03:02:36Z

←Older revision		Revision as of 03:02, 29 September 2014
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-	[[~~Image:~~2iwh.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF YEAST ELONGATION FACTOR 3 IN COMPLEX WITH ADPNP==
		+	<StructureSection load='2iwh' size='340' side='right' caption='[[2iwh]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IWH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2iw3\|2iw3]], [[2ix3\|2ix3]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iwh RCSB], [http://www.ebi.ac.uk/pdbsum/2iwh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iwh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Elongation factor eEF3 is an ATPase that, in addition to the two canonical factors eEF1A and eEF2, serves an essential function in the translation cycle of fungi. eEF3 is required for the binding of the aminoacyl-tRNA-eEF1A-GTP ternary complex to the ribosomal A-site and has been suggested to facilitate the clearance of deacyl-tRNA from the E-site. Here we present the crystal structure of Saccharomyces cerevisiae eEF3, showing that it consists of an amino-terminal HEAT repeat domain, followed by a four-helix bundle and two ABC-type ATPase domains, with a chromodomain inserted in ABC2. Moreover, we present the cryo-electron microscopy structure of the ATP-bound form of eEF3 in complex with the post-translocational-state 80S ribosome from yeast. eEF3 uses an entirely new factor binding site near the ribosomal E-site, with the chromodomain likely to stabilize the ribosomal L1 stalk in an open conformation, thus allowing tRNA release.

-	~~{{STRUCTURE_2iwh\| PDB=2iwh \| SCENE= }}~~	+	Structure of eEF3 and the mechanism of transfer RNA release from the E-site.,Andersen CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T, Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R Nature. 2006 Oct 12;443(7112):663-8. Epub 2006 Aug 23. PMID:16929303<ref>PMID:16929303</ref>

-	~~===STRUCTURE OF YEAST ELONGATION FACTOR 3 IN COMPLEX WITH ADPNP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16929303}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2iwh]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA].~~	+

	==See Also==		==See Also==
	*[[Elongation factor\|Elongation factor]]		*[[Elongation factor\|Elongation factor]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016929303<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Anand, M.]]		[[Category: Anand, M.]]

OCA: Protected "2iwh" [edit=sysop:move=sysop]

2012-10-20T10:00:22Z

Protected "2iwh" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:00, 20 October 2012

OCA at 10:00, 20 October 2012

2012-10-20T10:00:21Z

←Older revision		Revision as of 10:00, 20 October 2012
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-	{{Seed}}
	[[Image:2iwh.png\|left\|200px]]		[[Image:2iwh.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2iwh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2iwh\| PDB=2iwh \| SCENE= }}		{{STRUCTURE_2iwh\| PDB=2iwh \| SCENE= }}

	===STRUCTURE OF YEAST ELONGATION FACTOR 3 IN COMPLEX WITH ADPNP===		===STRUCTURE OF YEAST ELONGATION FACTOR 3 IN COMPLEX WITH ADPNP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16929303}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16929303 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16929303}}		{{ABSTRACT_PUBMED_16929303}}

	==About this Structure==		==About this Structure==
-	~~2IWH~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA].	+	[[2iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWH OCA].
		+
		+	==See Also==
		+	*[[Elongation factor\|Elongation factor]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16929303~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016929303</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Anand, M.]]		[[Category: Anand, M.]]
Line 38:		Line 29:
	[[Category: Pedersen, J S.]]		[[Category: Pedersen, J S.]]
	[[Category: Spahn, C M.T.]]		[[Category: Spahn, C M.T.]]
-	[[Category: Acetylation]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Elongation factor]]		[[Category: Elongation factor]]
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	[[Category: Rrna-binding]]		[[Category: Rrna-binding]]
	[[Category: Translation]]		[[Category: Translation]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:41:31 2009''