2iyj - Revision history

OCA at 14:29, 13 December 2023

2023-12-13T14:29:41Z

←Older revision		Revision as of 14:29, 13 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [https://pdbe.org/2iyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [https://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [https://pdbe.org/2iyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [https://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q14F36_ECOLX Q14F36_ECOLX] Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.[RuleBase:RU364038]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Metcalf, P]]	+	[[Category: Metcalf P]]
-	[[Category: Yeh, S M]]	+	[[Category: Yeh S-M]]
-	~~[[Category: Disulfide bond isomerase]]~~	+
-	~~[[Category: Dsbc]]~~	+
-	~~[[Category: Dsbg]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Periplasmic]]~~	+
-	~~[[Category: Redox-active center~~]]	+

OCA at 07:56, 19 January 2022

2022-01-19T07:56:58Z

←Older revision		Revision as of 07:56, 19 January 2022
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	<StructureSection load='2iyj' size='340' side='right'caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2iyj' size='340' side='right'caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [~~http~~://pdbe.org/2iyj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [https://pdbe.org/2iyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [https://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:34, 15 April 2020

2020-04-15T07:34:43Z

←Older revision		Revision as of 07:34, 15 April 2020
Line 1:		Line 1:

	==Crystal structure of the N-terminal dimer domain of E.coli DsbC==		==Crystal structure of the N-terminal dimer domain of E.coli DsbC==
-	<StructureSection load='2iyj' size='340' side='right' caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2iyj' size='340' side='right'caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://pdbe.org/2iyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://pdbe.org/2iyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]	+	*[[Thiol:disulfide interchange protein 3D structures\|Thiol:disulfide interchange protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
	[[Category: Metcalf, P]]		[[Category: Metcalf, P]]
	[[Category: Yeh, S M]]		[[Category: Yeh, S M]]

OCA at 07:00, 11 July 2018

2018-07-11T07:00:03Z

←Older revision		Revision as of 07:00, 11 July 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF THE~~ N-~~TERMINAL DIMER DOMAIN OF~~ E.~~COLI DSBC~~==	+
		+	==Crystal structure of the N-terminal dimer domain of E.coli DsbC==
	<StructureSection load='2iyj' size='340' side='right' caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2iyj' size='340' side='right' caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://pdbe.org/2iyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://pdbe.org/2iyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iyj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iyj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iyj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:02, 12 September 2015

2015-09-12T00:02:06Z

←Older revision		Revision as of 00:02, 12 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://pdbe.org/2iyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2iyj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:53, 19 January 2015

2015-01-19T13:53:40Z

←Older revision		Revision as of 13:53, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Metcalf, P.]]	+	[[Category: Metcalf, P]]
-	[[Category: Yeh, S M.]]	+	[[Category: Yeh, S M]]
	[[Category: Disulfide bond isomerase]]		[[Category: Disulfide bond isomerase]]
	[[Category: Dsbc]]		[[Category: Dsbc]]

OCA at 08:06, 30 September 2014

2014-09-30T08:06:48Z

←Older revision		Revision as of 08:06, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2iyj.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE N-TERMINAL DIMER DOMAIN OF E.COLI DSBC==
		+	<StructureSection load='2iyj' size='340' side='right' caption='[[2iyj]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1eej\|1eej]], [[1g0t\|1g0t]], [[1jzd\|1jzd]], [[1jzo\|1jzo]], [[1tjd\|1tjd]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyj RCSB], [http://www.ebi.ac.uk/pdbsum/2iyj PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iyj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DsbC and DsbG are periplasmic disulfide-bond isomerases, enzymes that facilitate the folding of secreted proteins with multiple disulfide bonds by catalyzing disulfide-bond rearrangement. Both enzymes also have in vitro chaperone activity. The crystal structures of these molecules are similar and both are V-shaped homodimeric modular structures. Each dimeric molecule contains two separate C-terminal thioredoxin-fold domains, joined by hinged helical "stalks" to a single N-terminal dimerization domain formed from the N-terminal 67 residues of each monomer. In this work, the crystal structures of the separate DsbC and DsbG dimerization domains have been determined at resolutions of 2.0 and 1.9 A, respectively. The two structures are both similar to the corresponding domains in the full-length molecules, showing that the dimerization domains fold independently of the catalytic portions of the full-length molecules. Localized structural differences between DsbC and DsbG were observed near the dimer interface and may be relevant to the different functions of the two enzymes.

-	~~{{STRUCTURE_2iyj\| PDB=2iyj \| SCENE= }}~~	+	Structures of the dimerization domains of the Escherichia coli disulfide-bond isomerase enzymes DsbC and DsbG.,Yeh SM, Koon N, Squire C, Metcalf P Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):465-71. Epub 2007, Mar 16. PMID:17372350<ref>PMID:17372350</ref>

-	~~===CRYSTAL STRUCTURE OF THE N-TERMINAL DIMER DOMAIN OF E.COLI DSBC===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17372350}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2iyj]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017372350<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Metcalf, P.]]		[[Category: Metcalf, P.]]

OCA: Protected "2iyj" [edit=sysop:move=sysop]

2013-01-07T13:10:23Z

Protected "2iyj" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:10, 7 January 2013

OCA at 13:10, 7 January 2013

2013-01-07T13:10:21Z

←Older revision		Revision as of 13:10, 7 January 2013
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-	{{Seed}}
	[[Image:2iyj.png\|left\|200px]]		[[Image:2iyj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2iyj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2iyj\| PDB=2iyj \| SCENE= }}		{{STRUCTURE_2iyj\| PDB=2iyj \| SCENE= }}

	===CRYSTAL STRUCTURE OF THE N-TERMINAL DIMER DOMAIN OF E.COLI DSBC===		===CRYSTAL STRUCTURE OF THE N-TERMINAL DIMER DOMAIN OF E.COLI DSBC===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17372350}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17372350 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17372350}}		{{ABSTRACT_PUBMED_17372350}}

	==About this Structure==		==About this Structure==
-	~~2IYJ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA].	+	[[2iyj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17372350~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017372350</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Metcalf, P.]]		[[Category: Metcalf, P.]]
-	[[Category: Yeh, S-.M.]]	+	[[Category: Yeh, S M.]]
	[[Category: Disulfide bond isomerase]]		[[Category: Disulfide bond isomerase]]
	[[Category: Dsbc]]		[[Category: Dsbc]]
Line 33:		Line 21:
	[[Category: Periplasmic]]		[[Category: Periplasmic]]
	[[Category: Redox-active center]]		[[Category: Redox-active center]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:41:04 2009''

OCA at 05:41, 18 February 2009

2009-02-18T05:41:05Z

←Older revision		Revision as of 05:41, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2IYJ is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA].	+	2IYJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYJ OCA].

	==Reference==		==Reference==
-	Structures of the dimerization domains of the Escherichia coli disulfide-bond isomerase enzymes DsbC and DsbG., Yeh SM, Koon N, Squire C, Metcalf P, Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):465-71. Epub 2007, Mar 16. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17372350 17372350]~~	+	<ref group="xtra">PMID:17372350</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Metcalf, P.]]		[[Category: Metcalf, P.]]
	[[Category: Yeh, S-.M.]]		[[Category: Yeh, S-.M.]]
Line 35:		Line 34:
	[[Category: Redox-active center]]		[[Category: Redox-active center]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 14:~~07:~~14 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:41:04 2009''