2k19 - Revision history

OCA at 09:43, 9 May 2024

2024-05-09T09:43:35Z

←Older revision		Revision as of 09:43, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [https://pdbe.org/2k19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [https://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [https://pdbe.org/2k19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [https://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:39, 14 June 2023

2023-06-14T08:39:35Z

←Older revision		Revision as of 08:39, 14 June 2023
Line 1:		Line 1:

	==NMR solution structure of PisI==		==NMR solution structure of PisI==
-	<StructureSection load='2k19' size='340' side='right'caption='[[2k19~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2k19' size='340' side='right'caption='[[2k19]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [https://pdbe.org/2k19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [https://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [https://pdbe.org/2k19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [https://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q2VU68_CARML Q2VU68_CARML]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Carnobacterium maltaromaticum]]		[[Category: Carnobacterium maltaromaticum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gursky~~, L J~~]]	+	[[Category: Gursky LJ]]
-	[[Category: Martin-Visscher~~, L A~~]]	+	[[Category: Martin-Visscher LA]]
-	[[Category: Sprules, T]]	+	[[Category: Sprules T]]
-	[[Category: Vederas~~, J C]]~~	+	[[Category: Vederas JC]]
-	~~[[Category: Antimicrobial protein]]~~	+
-	~~[[Category: Bacteriocin]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Immunity protein]]~~	+
-	~~[[Category: Pisi~~]]	+

OCA at 13:27, 24 November 2021

2021-11-24T13:27:18Z

←Older revision		Revision as of 13:27, 24 November 2021
Line 3:		Line 3:
	<StructureSection load='2k19' size='340' side='right'caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2k19' size='340' side='right'caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2K19 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [~~http~~://pdbe.org/2k19 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [https://pdbe.org/2k19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [https://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:53, 19 February 2020

2020-02-19T06:53:03Z

←Older revision		Revision as of 06:53, 19 February 2020
Line 1:		Line 1:

	==NMR solution structure of PisI==		==NMR solution structure of PisI==
-	<StructureSection load='2k19' size='340' side='right' caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2k19' size='340' side='right'caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Carnobacterium maltaromaticum]]		[[Category: Carnobacterium maltaromaticum]]
		+	[[Category: Large Structures]]
	[[Category: Gursky, L J]]		[[Category: Gursky, L J]]
	[[Category: Martin-Visscher, L A]]		[[Category: Martin-Visscher, L A]]

OCA at 11:17, 18 July 2018

2018-07-18T11:17:38Z

←Older revision		Revision as of 11:17, 18 July 2018
Line 1:		Line 1:
		+
	==NMR solution structure of PisI==		==NMR solution structure of PisI==
	<StructureSection load='2k19' size='340' side='right' caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2k19' size='340' side='right' caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://pdbe.org/2k19 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://pdbe.org/2k19 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k19 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k19_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k19_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k19 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:17, 11 September 2015

2015-09-11T21:17:30Z

←Older revision		Revision as of 21:17, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://pdbe.org/2k19 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2k19" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:00, 19 January 2015

2015-01-19T16:00:28Z

←Older revision		Revision as of 16:00, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Carnobacterium maltaromaticum]]		[[Category: Carnobacterium maltaromaticum]]
-	[[Category: Gursky, L J.]]	+	[[Category: Gursky, L J]]
-	[[Category: Martin-Visscher, L A.]]	+	[[Category: Martin-Visscher, L A]]
-	[[Category: Sprules, T.]]	+	[[Category: Sprules, T]]
-	[[Category: Vederas, J C.]]	+	[[Category: Vederas, J C]]
	[[Category: Antimicrobial protein]]		[[Category: Antimicrobial protein]]
	[[Category: Bacteriocin]]		[[Category: Bacteriocin]]

OCA at 09:04, 30 September 2014

2014-09-30T09:04:20Z

←Older revision		Revision as of 09:04, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2k19.~~png\|left~~\|200px]]	+	==NMR solution structure of PisI==
		+	<StructureSection load='2k19' size='340' side='right' caption='[[2k19]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K19 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pisI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2751 Carnobacterium maltaromaticum])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k19 RCSB], [http://www.ebi.ac.uk/pdbsum/2k19 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k19_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lactic acid bacteria produce and secrete bacteriocins. These bacteriocins are potent antimicrobial peptides that are active against other closely related bacteria. As a means of self-protection, producer organisms also express immunity proteins. Immunity proteins are generally located on the same genetic locus and are cotranscribed with the bacteriocin. Although some cross immunity between bacteriocins has been observed, immunity proteins are typically highly specific. Immunity proteins for the type IIa bacteriocins range from 81 to 115 amino acids in length and display substantial variation in their sequences. Nonetheless, such immunity proteins have been classified into three groupings (groups A, B, and C) according to sequence homology. The structures of a group C (ImB2) and two group A (EntA-im and PedB) immunity proteins have previously been reported. We herein report the nuclear magnetic resonance solution structure of the remaining class of the type IIa immunity proteins. PisI, a 98-amino acid protein, is a group B immunity protein conferring immunity against piscicolin 126 (PisA). Like ImB2, EntA-im, and PedB, PisI folds into a globular protein in aqueous solution and contains an antiparallel four-helix bundle. Compared to ImB2 and EntA-im, PisI has a substantially longer and more flexbile N-terminus, but a shorter C-terminus. No direct interaction between the bacteriocin and immunity protein is observed by NMR in either aqueous or membrane mimicking environments. This further suggests that the mechanism that mediates immunity is not due to a direct bacteriocin-immunity protein interaction but rather is receptor-mediated. It has now been confirmed that the four-helix bundle is indeed a structural motif among the type IIa immunity proteins.

-	~~{{STRUCTURE_2k19\| PDB=2k19 \| SCENE= }}~~	+	Nuclear magnetic resonance solution structure of PisI, a group B immunity protein that provides protection against the type IIa bacteriocin piscicolin 126, PisA.,Martin-Visscher LA, Sprules T, Gursky LJ, Vederas JC Biochemistry. 2008 Jun 17;47(24):6427-36. Epub 2008 May 24. PMID:18500825<ref>PMID:18500825</ref>

-	~~===NMR solution structure~~ of ~~PisI===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18500825}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2k19]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018500825<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Carnobacterium maltaromaticum]]		[[Category: Carnobacterium maltaromaticum]]
	[[Category: Gursky, L J.]]		[[Category: Gursky, L J.]]

OCA: Protected "2k19" [edit=sysop:move=sysop]

2013-01-07T11:23:31Z

Protected "2k19" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:23, 7 January 2013

OCA at 11:23, 7 January 2013

2013-01-07T11:23:27Z

←Older revision		Revision as of 11:23, 7 January 2013
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-	{{Seed}}
	[[Image:2k19.png\|left\|200px]]		[[Image:2k19.png\|left\|200px]]

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	{{STRUCTURE_2k19\| PDB=2k19 \| SCENE= }}		{{STRUCTURE_2k19\| PDB=2k19 \| SCENE= }}

	===NMR solution structure of PisI===		===NMR solution structure of PisI===

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-	<!--
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	{{ABSTRACT_PUBMED_18500825}}		{{ABSTRACT_PUBMED_18500825}}

	==About this Structure==		==About this Structure==
-	~~2K19~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA].	+	[[2k19]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnobacterium_maltaromaticum Carnobacterium maltaromaticum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K19 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18500825~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018500825</ref><references group="xtra"/>
	[[Category: Carnobacterium maltaromaticum]]		[[Category: Carnobacterium maltaromaticum]]
	[[Category: Gursky, L J.]]		[[Category: Gursky, L J.]]
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	[[Category: Immunity protein]]		[[Category: Immunity protein]]
	[[Category: Pisi]]		[[Category: Pisi]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:21:11 2009''