2kj7 - Revision history

OCA at 07:26, 14 April 2021

2021-04-14T07:26:53Z

←Older revision		Revision as of 07:26, 14 April 2021
Line 1:		Line 1:

	==Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles==		==Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles==
-	<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2kj7' size='340' side='right'caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [~~http~~://pdbe.org/2kj7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2kj7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2kj7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [https://pdbe.org/2kj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [https://www.ebi.ac.uk/pdbsum/2kj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kj7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/IAPP_RAT IAPP_RAT]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism (By similarity).	+	[[https://www.uniprot.org/uniprot/IAPP_RAT IAPP_RAT]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]
		+	[[Category: Large Structures]]
	[[Category: Brender, J R]]		[[Category: Brender, J R]]
	[[Category: Hartman, K]]		[[Category: Hartman, K]]

OCA at 10:07, 18 July 2018

2018-07-18T10:07:07Z

←Older revision		Revision as of 10:07, 18 July 2018
Line 1:		Line 1:
		+
	==Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles==		==Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles==
	<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://pdbe.org/2kj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://pdbe.org/2kj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kj7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 04:02, 10 February 2016

2016-02-10T04:02:32Z

←Older revision		Revision as of 04:02, 10 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kj7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:11, 11 September 2015

2015-09-11T05:11:28Z

←Older revision		Revision as of 05:11, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_norvegicus Rattus norvegicus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 ~~Rattus norvegicus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://pdbe.org/2kj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2kj7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rattus norvegicus~~]]	+	[[Category: Buffalo rat]]
	[[Category: Brender, J R]]		[[Category: Brender, J R]]
	[[Category: Hartman, K]]		[[Category: Hartman, K]]

OCA at 11:39, 25 December 2014

2014-12-25T11:39:52Z

←Older revision		Revision as of 11:39, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IAPP_RAT IAPP_RAT]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Brender, J R.]]	+	[[Category: Brender, J R]]
-	[[Category: Hartman, K.]]	+	[[Category: Hartman, K]]
-	[[Category: Nanga, R.]]	+	[[Category: Nanga, R]]
-	[[Category: Ramamoorthy, A.]]	+	[[Category: Ramamoorthy, A]]
-	[[Category: Subramanian, V.]]	+	[[Category: Subramanian, V]]
-	[[Category: Xu, J.]]	+	[[Category: Xu, J]]
	[[Category: Amidation]]		[[Category: Amidation]]
	[[Category: Amylin]]		[[Category: Amylin]]

OCA at 08:25, 30 September 2014

2014-09-30T08:25:30Z

←Older revision		Revision as of 08:25, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2kj7.~~png~~\|~~left~~\|200px]]	+	==Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles==
		+	<StructureSection load='2kj7' size='340' side='right' caption='[[2kj7]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Iapp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kj7 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Islet amyloid polypeptide (IAPP or amylin) is a 37-residue peptide hormone associated with glucose metabolism that is cosecreted with insulin by beta-cells in the pancreas. Since human IAPP is a highly amyloidogenic peptide, it has been suggested that the formation of IAPP amyloid fibers is responsible for the death of beta-cells during the early stages of type II diabetes. It has been hypothesized that transient membrane-bound alpha-helical structures of human IAPP are precursors to the formation of these amyloid deposits. On the other hand, rat IAPP forms transient alpha-helical structures but does not progress further to form amyloid fibrils. To understand the nature of this intermediate state and the difference in toxicity between the rat and human versions of IAPP, we have solved the high-resolution structure of rat IAPP in the membrane-mimicking detergent micelles composed of dodecylphosphocholine. The structure is characterized by a helical region spanning the residues A5 to S23 and a disordered C-terminus. A distortion in the helix is seen at R18 and S19 that may be involved in receptor binding. Paramagnetic quenching NMR experiments indicate that rat IAPP is bound on the surface of the micelle, in agreement with other nontoxic forms of IAPP. A comparison to the detergent-bound structures of other IAPP variants indicates that the N-terminal region may play a crucial role in the self-association and toxicity of IAPP by controlling access to the putative dimerization interface on the hydrophobic face of the amphipathic helix.

-	~~{{STRUCTURE_2kj7\| PDB=2kj7 \| SCENE= }}~~	+	Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.,Nanga RP, Brender JR, Xu J, Hartman K, Subramanian V, Ramamoorthy A J Am Chem Soc. 2009 Jun 17;131(23):8252-61. PMID:19456151<ref>PMID:19456151</ref>

-	~~===Three-Dimensional NMR Structure~~ of ~~Rat Islet Amyloid Polypeptide in DPC micelles===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19456151}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2kj7]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_norvegicus Rattus norvegicus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019456151<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Brender, J R.]]		[[Category: Brender, J R.]]

OCA: Protected "2kj7" [edit=sysop:move=sysop]

2013-01-07T10:49:54Z

Protected "2kj7" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:49, 7 January 2013

OCA at 10:49, 7 January 2013

2013-01-07T10:49:50Z

←Older revision		Revision as of 10:49, 7 January 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:2kj7.png\|left\|200px]]
-	[[Image:2kj7.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2kj7", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2kj7\| PDB=2kj7 \| SCENE= }}		{{STRUCTURE_2kj7\| PDB=2kj7 \| SCENE= }}

	===Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles===		===Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19456151}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19456151 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19456151}}		{{ABSTRACT_PUBMED_19456151}}

	==About this Structure==		==About this Structure==
-	~~2KJ7~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA].	+	[[2kj7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19456151~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019456151</ref><references group="xtra"/>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Brender, J R.]]		[[Category: Brender, J R.]]
Line 41:		Line 29:
	[[Category: Rat iapp]]		[[Category: Rat iapp]]
	[[Category: Secreted]]		[[Category: Secreted]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 09:05:31 2009''

OCA at 06:05, 25 June 2009

2009-06-25T06:05:33Z

←Older revision		Revision as of 06:05, 25 June 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2kj7.jpg\|left\|200px]]

-	The ~~entry 2kj7~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2kj7", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2kj7\| PDB=2kj7 \| SCENE= }}

-	~~Authors: Nanga, R., Jeffrey, B.R., Xu, J., Hartman, K., Subramanian, V., Ramamoorthy, A.~~	+	===Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles===

-	Description: Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in SDS micelles

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Jun ~~10 17~~:52:58 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19456151}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19456151 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19456151}}
		+
		+	==About this Structure==
		+	2KJ7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ7 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19456151</ref><references group="xtra"/>
		+	[[Category: Rattus norvegicus]]
		+	[[Category: Brender, J R.]]
		+	[[Category: Hartman, K.]]
		+	[[Category: Nanga, R.]]
		+	[[Category: Ramamoorthy, A.]]
		+	[[Category: Subramanian, V.]]
		+	[[Category: Xu, J.]]
		+	[[Category: Amidation]]
		+	[[Category: Amylin]]
		+	[[Category: Amyloid]]
		+	[[Category: Cleavage on pair of basic residue]]
		+	[[Category: Disulfide bond]]
		+	[[Category: Hormone]]
		+	[[Category: Iapp]]
		+	[[Category: Islet amyloid polypeptide]]
		+	[[Category: Rat iapp]]
		+	[[Category: Secreted]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 09:05:31 2009''

OCA at 14:52, 10 June 2009

2009-06-10T14:52:58Z

←Older revision		Revision as of 14:52, 10 June 2009
Line 5:		Line 5:
	Authors: Nanga, R., Jeffrey, B.R., Xu, J., Hartman, K., Subramanian, V., Ramamoorthy, A.		Authors: Nanga, R., Jeffrey, B.R., Xu, J., Hartman, K., Subramanian, V., Ramamoorthy, A.

-	Description: Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in SDS micelles.	+	Description: Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in SDS micelles

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Jun ~~4 07~~:16:22 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:52:58 2009''