2los - Revision history

OCA at 05:48, 15 May 2024

2024-05-15T05:48:02Z

←Older revision		Revision as of 05:48, 15 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [https://pdbe.org/2los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [https://www.ebi.ac.uk/pdbsum/2los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [https://pdbe.org/2los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [https://www.ebi.ac.uk/pdbsum/2los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 11:10, 15 February 2023

2023-02-15T11:10:57Z

←Older revision		Revision as of 11:10, 15 February 2023
Line 1:		Line 1:

	==Backbone structure of human membrane protein TMEM14C==		==Backbone structure of human membrane protein TMEM14C==
-	<StructureSection load='2los' size='340' side='right'caption='[[2los~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2los' size='340' side='right'caption='[[2los]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</div></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [https://pdbe.org/2los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [https://www.ebi.ac.uk/pdbsum/2los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [https://pdbe.org/2los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [https://www.ebi.ac.uk/pdbsum/2los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TM14C_HUMAN TM14C_HUMAN]] Required for normal heme biosynthesis (By similarity).	+	[https://www.uniprot.org/uniprot/TM14C_HUMAN TM14C_HUMAN] Required for normal heme biosynthesis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Choe, S]]	+	[[Category: Choe S]]
-	[[Category: Klammt, C]]	+	[[Category: Klammt C]]
-	[[Category: Maslennikov, I]]	+	[[Category: Maslennikov I]]
-	[[Category: Riek, R]]	+	[[Category: Riek R]]
-	[[Category: Vajpai, N]]	+	[[Category: Vajpai N]]
-	~~[[Category: Helical bundle]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Paramagnetic relaxation enhancement~~]]	+

OCA at 10:15, 12 May 2021

2021-05-12T10:15:15Z

←Older revision		Revision as of 10:15, 12 May 2021
Line 1:		Line 1:

	==Backbone structure of human membrane protein TMEM14C==		==Backbone structure of human membrane protein TMEM14C==
-	<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2los' size='340' side='right'caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [~~http~~://pdbe.org/2los PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2los PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [https://pdbe.org/2los PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [https://www.ebi.ac.uk/pdbsum/2los PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TM14C_HUMAN TM14C_HUMAN]] Required for normal heme biosynthesis (By similarity).	+	[[https://www.uniprot.org/uniprot/TM14C_HUMAN TM14C_HUMAN]] Required for normal heme biosynthesis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Choe, S]]		[[Category: Choe, S]]
	[[Category: Klammt, C]]		[[Category: Klammt, C]]

OCA at 19:45, 1 August 2018

2018-08-01T19:45:23Z

←Older revision		Revision as of 19:45, 1 August 2018
Line 1:		Line 1:
		+
	==Backbone structure of human membrane protein TMEM14C==		==Backbone structure of human membrane protein TMEM14C==
	<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://pdbe.org/2los PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://pdbe.org/2los PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2los ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 21:53, 10 September 2015

2015-09-10T21:53:13Z

←Older revision		Revision as of 21:53, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://pdbe.org/2los PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2los" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Choe, S]]		[[Category: Choe, S]]
	[[Category: Klammt, C]]		[[Category: Klammt, C]]

OCA at 06:34, 25 December 2014

2014-12-25T06:34:29Z

←Older revision		Revision as of 06:34, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TM14C_HUMAN TM14C_HUMAN]] Required for normal heme biosynthesis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:25, 22 December 2014

2014-12-22T06:25:11Z

←Older revision		Revision as of 06:25, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Choe, S.]]	+	[[Category: Choe, S]]
-	[[Category: Klammt, C.]]	+	[[Category: Klammt, C]]
-	[[Category: Maslennikov, I.]]	+	[[Category: Maslennikov, I]]
-	[[Category: Riek, R.]]	+	[[Category: Riek, R]]
-	[[Category: Vajpai, N.]]	+	[[Category: Vajpai, N]]
	[[Category: Helical bundle]]		[[Category: Helical bundle]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Paramagnetic relaxation enhancement]]		[[Category: Paramagnetic relaxation enhancement]]

OCA at 07:01, 9 June 2014

2014-06-09T07:01:19Z

←Older revision		Revision as of 07:01, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~2los.~~png~~\|~~left~~\|~~200px~~]]	+	==Backbone structure of human membrane protein TMEM14C==
		+	<StructureSection load='2los' size='340' side='right' caption='[[2los]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lom\|2lom]], [[2lon\|2lon]], [[2loo\|2loo]], [[2lop\|2lop]], [[2loq\|2loq]], [[2lor\|2lor]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMEM14C, C6orf53, HSPC194 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2los FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2los OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2los RCSB], [http://www.ebi.ac.uk/pdbsum/2los PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Although nearly half of today's major pharmaceutical drugs target human integral membrane proteins (hIMPs), only 30 hIMP structures are currently available in the Protein Data Bank, largely owing to inefficiencies in protein production. Here we describe a strategy for the rapid structure determination of hIMPs, using solution NMR spectroscopy with systematically labeled proteins produced via cell-free expression. We report new backbone structures of six hIMPs, solved in only 18 months from 15 initial targets. Application of our protocols to an additional 135 hIMPs with molecular weight <30 kDa yielded 38 hIMPs suitable for structural characterization by solution NMR spectroscopy without additional optimization.

-	~~{{STRUCTURE_2los\| PDB=2los \| SCENE= }}~~	+	Facile backbone structure determination of human membrane proteins by NMR spectroscopy.,Klammt C, Maslennikov I, Bayrhuber M, Eichmann C, Vajpai N, Chiu EJ, Blain KY, Esquivies L, Kwon JH, Balana B, Pieper U, Sali A, Slesinger PA, Kwiatkowski W, Riek R, Choe S Nat Methods. 2012 May 20;9(8):834-9. doi: 10.1038/nmeth.2033. PMID:22609626<ref>PMID:22609626</ref>

-	~~===Backbone structure~~ of ~~human membrane protein TMEM14C===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22609626}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2los]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022609626<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Choe, S.]]		[[Category: Choe, S.]]

OCA at 04:45, 15 August 2012

2012-08-15T04:45:07Z

←Older revision		Revision as of 04:45, 15 August 2012
Line 1:		Line 1:
-	[[Image:2los.~~jpg~~\|left\|200px]]	+	[[Image:2los.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2los", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2los\| PDB=2los \| SCENE= }}		{{STRUCTURE_2los\| PDB=2los \| SCENE= }}

	===Backbone structure of human membrane protein TMEM14C===		===Backbone structure of human membrane protein TMEM14C===

		+	{{ABSTRACT_PUBMED_22609626}}

	==About this Structure==		==About this Structure==
	[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA].		[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022609626</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Choe, S.]]		[[Category: Choe, S.]]

OCA at 06:08, 23 May 2012

2012-05-23T06:08:46Z

←Older revision		Revision as of 06:08, 23 May 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:2los.jpg\|left\|200px]]

-	The ~~entry 2los~~ is ~~ON HOLD~~ ~~until Jul 26 2013~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2los", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2los\| PDB=2los \| SCENE= }}

-	~~Authors: Klammt, C., Vajpai, N., Maslennikov, I., Riek, R., Choe, S.~~	+	===Backbone structure of human membrane protein TMEM14C===

-	~~Description: Backbone~~ structure ~~of human membrane~~ protein ~~TMEM14C~~	+
		+	==About this Structure==
		+	[[2los]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOS OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Choe, S.]]
		+	[[Category: Klammt, C.]]
		+	[[Category: Maslennikov, I.]]
		+	[[Category: Riek, R.]]
		+	[[Category: Vajpai, N.]]
		+	[[Category: Helical bundle]]
		+	[[Category: Membrane protein]]
		+	[[Category: Paramagnetic relaxation enhancement]]