2mio - Revision history

OCA at 06:06, 15 May 2024

2024-05-15T06:06:02Z

←Older revision		Revision as of 06:06, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [https://pdbe.org/2mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [https://www.ebi.ac.uk/pdbsum/2mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [https://pdbe.org/2mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [https://www.ebi.ac.uk/pdbsum/2mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:58, 8 March 2023

2023-03-08T07:58:27Z

←Older revision		Revision as of 07:58, 8 March 2023
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	==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==		==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==
-	<StructureSection load='2mio' size='340' side='right'caption='[[2mio~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2mio' size='340' side='right'caption='[[2mio]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [https://pdbe.org/2mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [https://www.ebi.ac.uk/pdbsum/2mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [https://pdbe.org/2mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [https://www.ebi.ac.uk/pdbsum/2mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).	+	[https://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

	==See Also==		==See Also==
Line 14:		Line 13:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Eletsky, A]]	+	[[Category: Eletsky A]]
-	[[Category: Everett~~, J K~~]]	+	[[Category: Everett JK]]
-	[[Category: Janjua, H]]	+	[[Category: Janjua H]]
-	[[Category: Montelione~~, G T]]~~	+	[[Category: Montelione GT]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Pulavarti SVSRK]]
-	[[Category: Pulavarti~~, S V.S R.K~~]]	+	[[Category: Sukumaran DK]]
-	[[Category: Sukumaran~~, D K~~]]	+	[[Category: Szyperski T]]
-	[[Category: Szyperski, T]]	+	[[Category: Wang H]]
-	[[Category: Wang, H]]	+	[[Category: Xiao R]]
-	[[Category: Xiao, R]]	+	[[Category: Xu X]]
-	[[Category: Xu, X]]	+
-	~~[[Category: Nesg]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Psi-biology]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 15:15, 2 June 2021

2021-06-02T15:15:16Z

←Older revision		Revision as of 15:15, 2 June 2021
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	==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==		==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==
-	<StructureSection load='2mio' size='340' side='right' caption='[[2mio]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2mio' size='340' side='right'caption='[[2mio]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [~~http~~://pdbe.org/2mio PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2mio PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [https://pdbe.org/2mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [https://www.ebi.ac.uk/pdbsum/2mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).	+	[[https://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

	==See Also==		==See Also==
-	*[[Rho GTPase activating protein\|Rho GTPase activating protein]]	+	*[[Rho GTPase activating protein 3D structures\|Rho GTPase activating protein 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Eletsky, A]]		[[Category: Eletsky, A]]
	[[Category: Everett, J K]]		[[Category: Everett, J K]]

OCA at 22:38, 9 August 2018

2018-08-09T22:38:11Z

←Older revision		Revision as of 22:38, 9 August 2018
Line 1:		Line 1:
		+
	==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==		==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==
	<StructureSection load='2mio' size='340' side='right' caption='[[2mio]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mio' size='340' side='right' caption='[[2mio]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://pdbe.org/2mio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://pdbe.org/2mio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).		[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
		+
		+	==See Also==
		+	*[[Rho GTPase activating protein\|Rho GTPase activating protein]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 21:45, 9 September 2015

2015-09-09T21:45:38Z

←Older revision		Revision as of 21:45, 9 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://pdbe.org/2mio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:48, 24 December 2014

2014-12-24T07:48:17Z

←Older revision		Revision as of 07:48, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:57, 21 December 2014

2014-12-21T17:57:56Z

←Older revision		Revision as of 17:57, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2mio\| PDB=2mio \| SCENE= }}~~	+	==Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A==
-	===Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A===	+	<StructureSection load='2mio' size='340' side='right' caption='[[2mio]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-		+	== Structural highlights ==
-	==~~Function~~==	+	<table><tr><td colspan='2'>[[2mio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIO FirstGlance]. <br>
-	[[http://~~www~~.~~uniprot~~.org/~~uniprot~~/~~RHG10_HUMAN RHG10_HUMAN~~]~~] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state~~. ~~Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases~~. ~~Inhibits PAK2 proteolytic fragment PAK~~-~~2p34 kinase activity and changes its localization from~~ the ~~nucleus to the perinuclear region~~. ~~Stabilizes PAK~~-~~2p34 thereby increasing stimulation of cell death (By similarity)~~.	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ARHGAP10, GRAF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mio RCSB], [http://www.ebi.ac.uk/pdbsum/2mio PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	</table>
-	[[2mio]~~] is a 1 chain structure. Full experimental information is available from~~ [http://oca.weizmann.ac.il/oca-bin/~~ocashort~~?id=~~2MIO~~ OCA].	+	__TOC__
-	[[Category: Eletsky, A.]]	+	</StructureSection>
-	[[Category: Everett, J K.]]	+	[[Category: Human]]
-	[[Category: Janjua, H.]]	+	[[Category: Eletsky, A]]
-	[[Category: Montelione, G T.]]	+	[[Category: Everett, J K]]
-	[[Category: ~~NESG, Northeast~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Janjua, H]]
-	[[Category: Pulavarti, S V.S R.K.]]	+	[[Category: Montelione, G T]]
-	[[Category: Sukumaran, D K.]]	+	[[Category: Structural genomic]]
-	[[Category: Szyperski, T.]]	+	[[Category: Pulavarti, S V.S R.K]]
-	[[Category: Wang, H.]]	+	[[Category: Sukumaran, D K]]
-	[[Category: Xiao, R.]]	+	[[Category: Szyperski, T]]
-	[[Category: Xu, X.]]	+	[[Category: Wang, H]]
		+	[[Category: Xiao, R]]
		+	[[Category: Xu, X]]
	[[Category: Nesg]]		[[Category: Nesg]]
-	[[Category: ~~Northeast structural genomics consortium]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
	[[Category: Psi-biology]]		[[Category: Psi-biology]]
-	[[Category: Structural genomic]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 12:11, 1 January 2014

2014-01-01T12:11:02Z

←Older revision		Revision as of 12:11, 1 January 2014
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-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_2mio\| PDB=2mio \| SCENE= }}
		+	===Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A===

-	~~The entry 2mio is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

-	~~Authors~~: ~~Xu, X~~., Eletsky, A., ~~Pulavarti, S.V.S.R.~~K.~~, Wang~~, H., ~~Janjua, H~~., ~~Xiao, R~~., ~~Everett, J~~.K., Sukumaran, D.T., ~~Montelione, G.T~~., ~~Szyperski, T~~., Northeast ~~Structural Genomics Consortium (NESG)~~	+	==About this Structure==
-		+	[[2mio]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA].
-	~~Description~~: ~~Solution NMR Structure of SH3 Domain 1 of Rho GTPase~~-~~activating Protein 10 from Homo sapiens, Northeast~~ Structural ~~Genomics Consortium (NESG) Target HR9129A~~	+	[[Category: Eletsky, A.]]
		+	[[Category: Everett, J K.]]
		+	[[Category: Janjua, H.]]
		+	[[Category: Montelione, G T.]]
		+	[[Category: NESG, Northeast Structural Genomics Consortium.]]
		+	[[Category: Pulavarti, S V.S R.K.]]
		+	[[Category: Sukumaran, D K.]]
		+	[[Category: Szyperski, T.]]
		+	[[Category: Wang, H.]]
		+	[[Category: Xiao, R.]]
		+	[[Category: Xu, X.]]
		+	[[Category: Nesg]]
		+	[[Category: Northeast structural genomics consortium]]
		+	[[Category: Protein structure initiative]]
		+	[[Category: Psi-biology]]
		+	[[Category: Structural genomic]]
		+	[[Category: Unknown function]]

OCA: Protected "2mio" [edit=sysop:move=sysop]

2013-12-25T09:01:20Z

Protected "2mio" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:01, 25 December 2013

OCA: New page: '''Unreleased structure''' The entry 2mio is ON HOLD Authors: Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.T., Montelione, G.T...

2013-12-25T09:01:19Z

New page: '''Unreleased structure''' The entry 2mio is ON HOLD Authors: Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.T., Montelione, G.T...

New page

'''Unreleased structure'''

The entry 2mio is ON HOLD

Authors: Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)

Description: Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A