2mvm - Revision history

OCA at 06:11, 15 May 2024

2024-05-15T06:11:05Z

←Older revision		Revision as of 06:11, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [https://pdbe.org/2mvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [https://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [https://pdbe.org/2mvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [https://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:08, 8 March 2023

2023-03-08T08:08:15Z

←Older revision		Revision as of 08:08, 8 March 2023
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	==Solution structure of eEF1Bdelta CAR domain==		==Solution structure of eEF1Bdelta CAR domain==
-	<StructureSection load='2mvm' size='340' side='right'caption='[[2mvm~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2mvm' size='340' side='right'caption='[[2mvm]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MVM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2mvn\|2mvn]]</div></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [https://pdbe.org/2mvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [https://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EEF1D, EF1D ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [https://pdbe.org/2mvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [https://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).	+	[https://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Feng, Y]]	+	[[Category: Feng Y]]
-	[[Category: Wu, H]]	+	[[Category: Wu H]]
-	~~[[Category: Guanine nucleotide exchange factor]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 15:21, 2 June 2021

2021-06-02T15:21:52Z

←Older revision		Revision as of 15:21, 2 June 2021
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	==Solution structure of eEF1Bdelta CAR domain==		==Solution structure of eEF1Bdelta CAR domain==
-	<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2mvm' size='340' side='right'caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MVM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2mvn\|2mvn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EEF1D, EF1D ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EEF1D, EF1D ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [~~http~~://pdbe.org/2mvm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [https://pdbe.org/2mvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [https://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).	+	[[https://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Elongation factor\|Elongation factor]]	+	*[[Elongation factor 3D structures\|Elongation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Feng, Y]]		[[Category: Feng, Y]]
	[[Category: Wu, H]]		[[Category: Wu, H]]
	[[Category: Guanine nucleotide exchange factor]]		[[Category: Guanine nucleotide exchange factor]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 07:46, 24 October 2018

2018-10-24T07:46:45Z

←Older revision		Revision as of 07:46, 24 October 2018
Line 3:		Line 3:
	<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MVM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EEF1D, EF1D ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [http://pdbe.org/2mvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [http://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [http://pdbe.org/2mvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [http://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>
	</table>		</table>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Feng, Y]]		[[Category: Feng, Y]]
	[[Category: Wu, H]]		[[Category: Wu, H]]
	[[Category: Guanine nucleotide exchange factor]]		[[Category: Guanine nucleotide exchange factor]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 17:31, 18 January 2017

2017-01-18T17:31:57Z

←Older revision		Revision as of 17:31, 18 January 2017
Line 1:		Line 1:
		+
	==Solution structure of eEF1Bdelta CAR domain==		==Solution structure of eEF1Bdelta CAR domain==
	<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [http://www.ebi.ac.uk/pdbsum/2mvm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [http://pdbe.org/2mvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [http://www.ebi.ac.uk/pdbsum/2mvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2mvm" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 07:00, 15 April 2015

2015-04-15T07:00:56Z

←Older revision		Revision as of 07:00, 15 April 2015
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Elongation factor\|Elongation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:29, 12 February 2015

2015-02-12T06:29:41Z

←Older revision		Revision as of 06:29, 12 February 2015
Line 8:		Line 8:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).		[[http://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Translationally-controlled tumor protein (TCTP) is an abundant protein which is highly conserved in eukaryotes. However, its primary function is still not clear. Human TCTP interacts with the metazoan-specific eukaryotic elongation factor 1Bdelta (eEF1Bdelta) and inhibits its guanine nucleotide exchange factor (GEF) activity, but the structural mechanism remains unknown. The interaction between TCTP and eEF1Bdelta was investigated by NMR titration, structure determination, paramagnetic relaxation enhancement, site-directed mutagenesis, isothermal titration calorimetry, and HADDOCK docking. We first demonstrated that the catalytic GEF domain of eEF1Bdelta is not responsible for binding to TCTP, but rather a previously unnoticed central acidic region (CAR) domain in eEF1Bdelta. The mutagenesis data and the structural model of the TCTP-eEF1Bdelta CAR domain complex revealed the key binding residues. These residues are highly conserved in eukaryotic TCTPs and in eEF1B GEFs including the eukaryotically-conserved eEF1Balpha, implying the interaction may be conserved in all eukaryotes. Interactions were confirmed between TCTP and the eEF1Balpha CAR domain for human, fission yeast and unicellular photosynthetic microalga proteins, suggesting that involvement in protein translation through the conserved interaction with eEF1B represents a primary function of TCTP.
		+
		+	Evolutionarily Conserved Binding of Translationally-Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.,Wu H, Gong W, Yao X, Wang J, Perrett S, Feng Y J Biol Chem. 2015 Jan 29. pii: jbc.M114.628594. PMID:25635048<ref>PMID:25635048</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 15:52, 7 February 2015

2015-02-07T15:52:43Z

←Older revision		Revision as of 15:52, 7 February 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Solution structure of eEF1Bdelta CAR domain==
-		+	<StructureSection load='2mvm' size='340' side='right' caption='[[2mvm]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~The entry~~ 2mvm is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2mvm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MVM FirstGlance]. <br>
-	~~Authors~~: Wu, H., ~~Feng~~, Y.	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2mvn\|2mvn]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mvm RCSB], [http://www.ebi.ac.uk/pdbsum/2mvm PDBsum]</span></td></tr>
-	~~Description: Solution structure of eEF1Bdelta CAR domain~~	+	</table>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/EF1D_HUMAN EF1D_HUMAN]] Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
		+	__TOC__
		+	</StructureSection>
	[[Category: Feng, Y]]		[[Category: Feng, Y]]
	[[Category: Wu, H]]		[[Category: Wu, H]]
		+	[[Category: Guanine nucleotide exchange factor]]
		+	[[Category: Translation]]

OCA at 12:29, 24 December 2014

2014-12-24T12:29:40Z

←Older revision		Revision as of 12:29, 24 December 2014
Line 6:		Line 6:

	Description: Solution structure of eEF1Bdelta CAR domain		Description: Solution structure of eEF1Bdelta CAR domain
		+	[[Category: Unreleased Structures]]
		+	[[Category: Feng, Y]]
		+	[[Category: Wu, H]]

OCA at 09:38, 29 October 2014

2014-10-29T09:38:51Z

←Older revision		Revision as of 09:38, 29 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2mvm is ON HOLD	+	The entry 2mvm is ON HOLD until Paper Publication

	Authors: Wu, H., Feng, Y.		Authors: Wu, H., Feng, Y.

	Description: Solution structure of eEF1Bdelta CAR domain		Description: Solution structure of eEF1Bdelta CAR domain