2o7h - Revision history

OCA at 10:36, 16 August 2023

2023-08-16T10:36:42Z

←Older revision		Revision as of 10:36, 16 August 2023
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	<StructureSection load='2o7h' size='340' side='right'caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='2o7h' size='340' side='right'caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7H FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2zta\|2zta]], [[1zij\|1zij]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">GCN4 ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=4932 ATCC 18824])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [https://pdbe.org/2o7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [https://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [https://pdbe.org/2o7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [https://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.	+	[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 20:

	==See Also==		==See Also==
		+	*[[Gcn4 3D Structures\|Gcn4 3D Structures]]
	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]		*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Honnappa, S~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: ~~Jawhari, H~~]]	+	[[Category: Honnappa S]]
-	[[Category: ~~Steinmetz, M O~~]]	+	[[Category: Jawhari H]]
-	[[Category: ~~Activator]]~~	+	[[Category: Steinmetz MO]]
-	~~[[Category: Amino-acid biosynthesis]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Nuclear protein]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription regulation]]~~	+
-	~~[[Category: Trimeric coiled coil~~]]	+

OCA at 16:02, 8 June 2021

2021-06-08T16:02:10Z

←Older revision		Revision as of 16:02, 8 June 2021
Line 1:		Line 1:

	==Crystal structure of trimeric coiled coil GCN4 leucine zipper==		==Crystal structure of trimeric coiled coil GCN4 leucine zipper==
-	<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='2o7h' size='340' side='right'caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2O7H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7H FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zta\|2zta]], [[1zij\|1zij]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [~~http~~://pdbe.org/2o7h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7h ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [https://pdbe.org/2o7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [https://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.	+	[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 2o7h" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2o7h" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Honnappa, S]]		[[Category: Honnappa, S]]
	[[Category: Jawhari, H]]		[[Category: Jawhari, H]]

OCA at 08:53, 18 October 2017

2017-10-18T08:53:18Z

←Older revision		Revision as of 08:53, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of trimeric coiled coil GCN4 leucine zipper==		==Crystal structure of trimeric coiled coil GCN4 leucine zipper==
	<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://pdbe.org/2o7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://pdbe.org/2o7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 2o7h" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2o7h" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Gcn4\|Gcn4]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:27, 11 September 2015

2015-09-11T07:27:54Z

←Older revision		Revision as of 07:27, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7H FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://pdbe.org/2o7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2o7h" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Honnappa, S]]		[[Category: Honnappa, S]]
	[[Category: Jawhari, H]]		[[Category: Jawhari, H]]

OCA at 13:13, 25 December 2014

2014-12-25T13:13:39Z

←Older revision		Revision as of 13:13, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Gcn4\|Gcn4]]
	== References ==		== References ==
	<references/>		<references/>
Line 20:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Honnappa, S.]]	+	[[Category: Honnappa, S]]
-	[[Category: Jawhari, H.]]	+	[[Category: Jawhari, H]]
-	[[Category: Steinmetz, M O.]]	+	[[Category: Steinmetz, M O]]
	[[Category: Activator]]		[[Category: Activator]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]

OCA at 11:51, 29 October 2014

2014-10-29T11:51:58Z

←Older revision		Revision as of 11:51, 29 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2o7h.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of trimeric coiled coil GCN4 leucine zipper==
		+	<StructureSection load='2o7h' size='340' side='right' caption='[[2o7h]], [[Resolution\|resolution]] 1.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2o7h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7H FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zta\|2zta]], [[1zij\|1zij]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GCN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7h RCSB], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Coiled coils are extensively and successfully used nowadays to rationally design multistranded structures for applications, including basic research, biotechnology, nanotechnology, materials science, and medicine. The wide range of applications as well as the important functions these structures play in almost all biological processes highlight the need for a detailed understanding of the factors that control coiled-coil folding and oligomerization. Here, we address the important and unresolved question why the presence of particular oligomerization-state determinants within a coiled coil does frequently not correlate with its topology. We found an unexpected, general link between coiled-coil oligomerization-state specificity and trigger sequences, elements that are indispensable for coiled-coil formation. By using the archetype coiled-coil domain of the yeast transcriptional activator GCN4 as a model system, we show that well-established trimer-specific oligomerization-state determinants switch the peptide's topology from a dimer to a trimer only when inserted into the trigger sequence. We successfully confirmed our results in two other, unrelated coiled-coil dimers, ATF1 and cortexillin-1. We furthermore show that multiple topology determinants can coexist in the same trigger sequence, revealing a delicate balance of the resulting oligomerization state by position-dependent forces. Our experimental results should significantly improve the prediction of the oligomerization state of coiled coils. They therefore should have major implications for the rational design of coiled coils and consequently many applications using these popular oligomerization domains.

-	~~{{STRUCTURE_2o7h\| PDB=2o7h \| SCENE= }}~~	+	Molecular basis of coiled-coil oligomerization-state specificity.,Ciani B, Bjelic S, Honnappa S, Jawhari H, Jaussi R, Payapilly A, Jowitt T, Steinmetz MO, Kammerer RA Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19850-5. Epub 2010 Nov 2. PMID:21045134<ref>PMID:21045134</ref>

-	~~===Crystal structure~~ of ~~trimeric coiled coil GCN4 leucine zipper===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21045134}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2o7h]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021045134<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Honnappa, S.]]		[[Category: Honnappa, S.]]

OCA at 08:46, 16 January 2013

2013-01-16T08:46:45Z

←Older revision		Revision as of 08:46, 16 January 2013
Line 5:		Line 5:
	===Crystal structure of trimeric coiled coil GCN4 leucine zipper===		===Crystal structure of trimeric coiled coil GCN4 leucine zipper===

-	{{~~ABSTRACT_PUBMED_021045134~~}}	+	{{ABSTRACT_PUBMED_21045134}}

	==About this Structure==		==About this Structure==

OCA: Protected "2o7h" [edit=sysop:move=sysop]

2012-08-14T14:44:43Z

Protected "2o7h" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:44, 14 August 2012

OCA at 14:44, 14 August 2012

2012-08-14T14:44:41Z

←Older revision		Revision as of 14:44, 14 August 2012
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-	[[Image:2o7h.~~jpg~~\|left\|200px]]	+	[[Image:2o7h.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2o7h", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2o7h\| PDB=2o7h \| SCENE= }}		{{STRUCTURE_2o7h\| PDB=2o7h \| SCENE= }}

-	~~'''~~Crystal structure of trimeric coiled coil GCN4 leucine zipper~~'''~~	+	===Crystal structure of trimeric coiled coil GCN4 leucine zipper===

		+	{{ABSTRACT_PUBMED_021045134}}

	==About this Structure==		==About this Structure==
-	~~2O7H is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA].	+	[[2o7h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7H OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021045134</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Single protein]]
	[[Category: Honnappa, S.]]		[[Category: Honnappa, S.]]
	[[Category: Jawhari, H.]]		[[Category: Jawhari, H.]]
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	[[Category: Dna-binding]]		[[Category: Dna-binding]]
	[[Category: Nuclear protein]]		[[Category: Nuclear protein]]
		+	[[Category: Transcription]]
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
	[[Category: Trimeric coiled coil]]		[[Category: Trimeric coiled coil]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 10:25:02 2008''

OCA at 07:25, 4 May 2008

2008-05-04T07:25:03Z

←Older revision		Revision as of 07:25, 4 May 2008
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	[[Image:2o7h.jpg\|left\|200px]]		[[Image:2o7h.jpg\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 2o7h \|SIZE=350\|CAPTION= <scene name='initialview01'>2o7h</scene>~~, ~~resolution 1~~.~~86Å~~	+	The line below this paragraph, containing "STRUCTURE_2o7h", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND=~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY=~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE= GCN4~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]~~)	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_2o7h\| PDB=2o7h \| SCENE= }}
-	~~\|RELATEDENTRY=[[2zta\|2ZTA]]~~, ~~[[1zij\|1ZIJ]]~~	+
-	~~\|RESOURCES=<span class='plainlinks'>[http://oca~~.~~weizmann.ac.il/oca~~-~~docs/fgij/fg.htm?mol=2o7h FirstGlance], [http://oca.weizmann.ac.il/oca~~-~~bin/ocaids?id~~=2o7h ~~OCA], [http://www.ebi.ac.uk/pdbsum/2o7h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId~~=~~2o7h RCSB]</span>~~	+
-	}}	+

	'''Crystal structure of trimeric coiled coil GCN4 leucine zipper'''		'''Crystal structure of trimeric coiled coil GCN4 leucine zipper'''
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	[[Category: Jawhari, H.]]		[[Category: Jawhari, H.]]
	[[Category: Steinmetz, M O.]]		[[Category: Steinmetz, M O.]]
-	[[Category: ~~activator~~]]	+	[[Category: Activator]]
-	[[Category: ~~amino~~-acid biosynthesis]]	+	[[Category: Amino-acid biosynthesis]]
-	[[Category: ~~dna~~-binding]]	+	[[Category: Dna-binding]]
-	[[Category: ~~nuclear~~ protein]]	+	[[Category: Nuclear protein]]
-	[[Category: ~~transcription~~ regulation]]	+	[[Category: Transcription regulation]]
-	[[Category: ~~trimeric~~ coiled coil]]	+	[[Category: Trimeric coiled coil]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 10:25:02 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 04~~:13:50 2008''	+