2o7x - Revision history

OCA at 14:19, 29 November 2023

2023-11-29T14:19:00Z

←Older revision		Revision as of 14:19, 29 November 2023
Line 1:		Line 1:

	==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==		==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==
-	<StructureSection load='2o7x' size='340' side='right'caption='[[2o7x~~]], [[NMR_Ensembles_of_Models \| 11 NMR models~~]]' scene=''>	+	<StructureSection load='2o7x' size='340' side='right'caption='[[2o7x]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [https://pdbe.org/2o7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [https://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [https://pdbe.org/2o7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [https://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Case~~, D A~~]]	+	[[Category: Case DA]]
-	[[Category: Chen, J]]	+	[[Category: Chen J]]
-	[[Category: Dupradeau~~, F Y~~]]	+	[[Category: Dupradeau FY]]
-	[[Category: Stubbe, J]]	+	[[Category: Stubbe J]]
-	[[Category: Turner~~, C J]]~~	+	[[Category: Turner CJ]]
-	~~[[Category: Abasic]]~~	+
-	~~[[Category: Amber]]~~	+
-	~~[[Category: Ape1]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Dna damage]]~~	+
-	~~[[Category: Molecular dynamic~~]]	+

OCA at 07:50, 2 March 2022

2022-03-02T07:50:25Z

←Older revision		Revision as of 07:50, 2 March 2022
Line 3:		Line 3:
	<StructureSection load='2o7x' size='340' side='right'caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>		<StructureSection load='2o7x' size='340' side='right'caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2O7X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [~~http~~://pdbe.org/2o7x PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [https://pdbe.org/2o7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [https://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:58, 27 May 2020

2020-05-27T07:58:28Z

←Older revision		Revision as of 07:58, 27 May 2020
Line 1:		Line 1:

	==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==		==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==
-	<StructureSection load='2o7x' size='340' side='right' caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>	+	<StructureSection load='2o7x' size='340' side='right'caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2O7X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://pdbe.org/2o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://pdbe.org/2o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Case, D A]]		[[Category: Case, D A]]
	[[Category: Chen, J]]		[[Category: Chen, J]]

OCA at 06:55, 22 August 2018

2018-08-22T06:55:43Z

←Older revision		Revision as of 06:55, 22 August 2018
Line 1:		Line 1:
		+
	==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==		==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==
	<StructureSection load='2o7x' size='340' side='right' caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>		<StructureSection load='2o7x' size='340' side='right' caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://pdbe.org/2o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://pdbe.org/2o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o7x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:54, 11 September 2015

2015-09-11T00:54:59Z

←Older revision		Revision as of 00:54, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://pdbe.org/2o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2o7x" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:34, 5 January 2015

2015-01-05T12:34:49Z

←Older revision		Revision as of 12:34, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Case, D A.]]	+	[[Category: Case, D A]]
-	[[Category: Chen, J.]]	+	[[Category: Chen, J]]
-	[[Category: Dupradeau, F Y.]]	+	[[Category: Dupradeau, F Y]]
-	[[Category: Stubbe, J.]]	+	[[Category: Stubbe, J]]
-	[[Category: Turner, C J.]]	+	[[Category: Turner, C J]]
	[[Category: Abasic]]		[[Category: Abasic]]
	[[Category: Amber]]		[[Category: Amber]]

OCA at 06:20, 9 July 2014

2014-07-09T06:20:39Z

←Older revision		Revision as of 06:20, 9 July 2014
Line 1:		Line 1:
-	[[~~Image:~~2o7x.~~png~~\|~~left\|200px~~]]	+	==Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)==
		+	<StructureSection load='2o7x' size='340' side='right' caption='[[2o7x]], [[NMR_Ensembles_of_Models \| 11 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O7X FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAB:2-DEOXY-RIBOFURANOSE-5-MONOPHOSPHATE'>AAB</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o7x RCSB], [http://www.ebi.ac.uk/pdbsum/2o7x PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Abasic sites are common DNA lesions resulting from spontaneous depurination and excision of damaged nucleobases by DNA repair enzymes. However, the influence of the local sequence context on the structure of the abasic site and ultimately, its recognition and repair, remains elusive. In the present study, duplex DNAs with three different bases (G, C or T) opposite an abasic site have been synthesized in the same sequence context (5'-CCA AAG6 XA8C CGG G-3', where X denotes the abasic site) and characterized by 2D NMR spectroscopy. Studies on a duplex DNA with an A opposite the abasic site in the same sequence has recently been reported [Chen,J., Dupradeau,F.-Y., Case,D.A., Turner,C.J. and Stubbe,J. (2007) Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites. Biochemistry, 46, 3096-3107]. Molecular modeling based on NMR-derived distance and dihedral angle restraints and molecular dynamics calculations have been applied to determine structural models and conformational flexibility of each duplex. The results indicate that all four duplexes adopt an overall B-form conformation with each unpaired base stacked between adjacent bases intrahelically. The conformation around the abasic site is more perturbed when the base opposite to the lesion is a pyrimidine (C or T) than a purine (G or A). In both the former cases, the neighboring base pairs (G6-C21 and A8-T19) are closer to each other than those in B-form DNA. Molecular dynamics simulations reveal that transient H-bond interactions between the unpaired pyrimidine (C20 or T20) and the base 3' to the abasic site play an important role in perturbing the local conformation. These results provide structural insight into the dynamics of abasic sites that are intrinsically modulated by the bases opposite the abasic site.

-	~~{{STRUCTURE_2o7x\| PDB=2o7x \| SCENE= }}~~	+	DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics.,Chen J, Dupradeau FY, Case DA, Turner CJ, Stubbe J Nucleic Acids Res. 2008 Jan;36(1):253-62. Epub 2007 Nov 19. PMID:18025040<ref>PMID:18025040</ref>

-	~~===Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18025040}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2o7x]] is~~ a ~~2 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2O7X OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018025040<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Case, D A.]]		[[Category: Case, D A.]]
	[[Category: Chen, J.]]		[[Category: Chen, J.]]

OCA: Protected "2o7x" [edit=sysop:move=sysop]

2013-01-07T12:19:29Z

Protected "2o7x" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:19, 7 January 2013

OCA at 12:19, 7 January 2013

2013-01-07T12:19:24Z

←Older revision		Revision as of 12:19, 7 January 2013
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-	{{Seed}}
	[[Image:2o7x.png\|left\|200px]]		[[Image:2o7x.png\|left\|200px]]

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	{{STRUCTURE_2o7x\| PDB=2o7x \| SCENE= }}		{{STRUCTURE_2o7x\| PDB=2o7x \| SCENE= }}

	===Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)===		===Duplex DNA containing an abasic site with an opposite G (beta anomer) in 5'-G_AC-3' (10 structure ensemble and averaged structure)===

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	{{ABSTRACT_PUBMED_18025040}}		{{ABSTRACT_PUBMED_18025040}}

	==About this Structure==		==About this Structure==
-	~~2O7X~~ is a 2 ~~chains~~ structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA].	+	[[2o7x]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O7X OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18025040~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018025040</ref><references group="xtra"/>
	[[Category: Case, D A.]]		[[Category: Case, D A.]]
	[[Category: Chen, J.]]		[[Category: Chen, J.]]
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	[[Category: Amber]]		[[Category: Amber]]
	[[Category: Ape1]]		[[Category: Ape1]]
		+	[[Category: Dna]]
	[[Category: Dna damage]]		[[Category: Dna damage]]
	[[Category: Molecular dynamic]]		[[Category: Molecular dynamic]]
-	[[Category: Nmr]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:37:34 2009''

OCA at 05:37, 16 September 2009

2009-09-16T05:37:35Z

←Older revision		Revision as of 05:37, 16 September 2009
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	==Reference==		==Reference==
-	~~DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics., Chen J, Dupradeau FY, Case DA, Turner CJ, Stubbe J, Nucleic Acids Res. 2008 Jan;36(1):253-62. Epub 2007 Nov 19.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18025040 18025040]~~	+	<ref group="xtra">PMID:18025040</ref><references group="xtra"/>
	[[Category: Case, D A.]]		[[Category: Case, D A.]]
	[[Category: Chen, J.]]		[[Category: Chen, J.]]
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	[[Category: Nmr]]		[[Category: Nmr]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Nov 27 13~~:49:~~24 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:37:34 2009''