2obs - Revision history

OCA at 08:57, 25 October 2023

2023-10-25T08:57:10Z

←Older revision		Revision as of 08:57, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2obr\|2obr]], [[2obt\|2obt]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [https://pdbe.org/2obs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [https://www.ebi.ac.uk/pdbsum/2obs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2obs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [https://pdbe.org/2obs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [https://www.ebi.ac.uk/pdbsum/2obs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2obs ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q913Z3_9CALI Q913Z3_9CALI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Norovirus]]		[[Category: Norovirus]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
-	[[Category: Cao, S]]	+	[[Category: Cao S]]
-	[[Category: Li, X]]	+	[[Category: Li X]]
-	[[Category: Rao, Z]]	+	[[Category: Rao Z]]
-	~~[[Category: Blood group trisaccharides type some]]~~	+
-	~~[[Category: Crystal structure]]~~	+
-	~~[[Category: Norovirus va387]]~~	+
-	~~[[Category: P domain]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 12:52, 9 June 2021

2021-06-09T12:52:17Z

←Older revision		Revision as of 12:52, 9 June 2021
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	<StructureSection load='2obs' size='340' side='right'caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2obs' size='340' side='right'caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [~~http~~://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [~~http~~://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2OBS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2obr\|2obr]], [[2obt\|2obt]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [~~http~~://pdbe.org/2obs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2obs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2obs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [https://pdbe.org/2obs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [https://www.ebi.ac.uk/pdbsum/2obs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2obs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:04, 31 July 2019

2019-07-31T08:04:08Z

←Older revision		Revision as of 08:04, 31 July 2019
Line 1:		Line 1:

	==Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A==		==Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A==
-	<StructureSection load='2obs' size='340' side='right' caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2obs' size='340' side='right'caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/2obs_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/2obs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2obs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2obs" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: ABO Blood Type Glycosyltransferases]]		[[Category: ABO Blood Type Glycosyltransferases]]
		+	[[Category: Large Structures]]
	[[Category: Norovirus]]		[[Category: Norovirus]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]

OCA at 08:56, 18 October 2017

2017-10-18T08:56:38Z

←Older revision		Revision as of 08:56, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A==		==Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A==
	<StructureSection load='2obs' size='340' side='right' caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2obs' size='340' side='right' caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. The December 2012 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://pdbe.org/2obs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://pdbe.org/2obs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2obs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2obs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2obs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2obs" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Virus coat protein\|Virus coat protein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: ABO Blood Type Glycosyltransferases]]
	[[Category: Norovirus]]		[[Category: Norovirus]]
		+	[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Cao, S]]		[[Category: Cao, S]]
	[[Category: Li, X]]		[[Category: Li, X]]

OCA at 10:21, 11 September 2015

2015-09-11T10:21:32Z

←Older revision		Revision as of 10:21, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://pdbe.org/2obs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2obs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:42, 19 January 2015

2015-01-19T18:42:41Z

←Older revision		Revision as of 18:42, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Norovirus]]		[[Category: Norovirus]]
-	[[Category: Cao, S.]]	+	[[Category: Cao, S]]
-	[[Category: Li, X.]]	+	[[Category: Li, X]]
-	[[Category: Rao, Z.]]	+	[[Category: Rao, Z]]
	[[Category: Blood group trisaccharides type some]]		[[Category: Blood group trisaccharides type some]]
	[[Category: Crystal structure]]		[[Category: Crystal structure]]

OCA at 10:33, 29 September 2014

2014-09-29T10:33:00Z

←Older revision		Revision as of 10:33, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2obs.~~png~~\|~~left~~\|200px]]	+	==Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A==
		+	<StructureSection load='2obs' size='340' side='right' caption='[[2obs]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OBS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GL0:BETA-D-GULOPYRANOSE'>GL0</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2obr\|2obr]], [[2obt\|2obt]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2obs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2obs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2obs RCSB], [http://www.ebi.ac.uk/pdbsum/2obs PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/2obs_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Noroviruses are one of the major causes of nonbacterial gastroenteritis epidemics in humans. Recent studies on norovirus receptors show that different noroviruses recognize different human histo-blood group antigens (HBGAs), and eight receptor binding patterns of noroviruses have been identified. The P domain of the norovirus capsids is directly involved in this recognition. To determine the precise locations and receptor binding modes of HBGA carbohydrates on the viral capsids, a recombinant P protein of a GII-4 strain norovirus, VA387, was cocrystallized with synthetic type A or B trisaccharides. Based on complex crystal structures observed at a 2.0-A resolution, we demonstrated that the receptor binding site lies at the outermost end of the P domain and forms an extensive hydrogen-bonding network with the saccharide ligand. The A and B trisaccharides display similar binding modes, and the common fucose ring plays a key role in this interaction. The extensive interface between the two protomers in a P dimer also plays a crucial role in the formation of the receptor binding interface.

-	~~{{STRUCTURE_2obs\| PDB=2obs \| SCENE= }}~~	+	Structural basis for the recognition of blood group trisaccharides by norovirus.,Cao S, Lou Z, Tan M, Chen Y, Liu Y, Zhang Z, Zhang XC, Jiang X, Li X, Rao Z J Virol. 2007 Jun;81(11):5949-57. Epub 2007 Mar 28. PMID:17392366<ref>PMID:17392366</ref>

-	~~===Crystal Structures~~ of ~~P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17392366}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2obs]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Norovirus Norovirus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA].~~	+

	==See Also==		==See Also==
	*[[Virus coat protein\|Virus coat protein]]		*[[Virus coat protein\|Virus coat protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017392366<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Norovirus]]		[[Category: Norovirus]]
	[[Category: Cao, S.]]		[[Category: Cao, S.]]

OCA at 18:08, 20 October 2012

2012-10-20T18:08:50Z

←Older revision		Revision as of 18:08, 20 October 2012
Line 1:		Line 1:
	[[Image:2obs.png\|left\|200px]]		[[Image:2obs.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2obs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2obs\| PDB=2obs \| SCENE= }}		{{STRUCTURE_2obs\| PDB=2obs \| SCENE= }}

	===Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A===		===Crystal Structures of P Domain of Norovirus VA387 in Complex with Blood Group Trisaccharides type A===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17392366}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17392366 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17392366}}		{{ABSTRACT_PUBMED_17392366}}

	==About this Structure==		==About this Structure==
	[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA].		[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA].
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==

OCA: Protected "2obs" [edit=sysop:move=sysop]

2011-08-24T06:50:43Z

Protected "2obs" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:50, 24 August 2011

OCA at 06:50, 24 August 2011

2011-08-24T06:50:41Z

←Older revision		Revision as of 06:50, 24 August 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2obs.png\|left\|200px]]		[[Image:2obs.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2OBS~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA].	+	[[2obs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBS OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17392366~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017392366</ref><references group="xtra"/>
	[[Category: Norovirus]]		[[Category: Norovirus]]
	[[Category: Cao, S.]]		[[Category: Cao, S.]]
Line 32:		Line 31:
	[[Category: Norovirus va387]]		[[Category: Norovirus va387]]
	[[Category: P domain]]		[[Category: P domain]]
-		+	[[Category: Viral protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 19:47:20 2009''~~	+