2ome - Revision history

OCA at 10:43, 30 August 2023

2023-08-30T10:43:19Z

←Older revision		Revision as of 10:43, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2ome' size='340' side='right'caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ome' size='340' side='right'caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OME FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OME FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NAD:NICOTINAMIDE~~-~~ADENINE-DINUCLEOTIDE'>NAD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CTBP2 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [https://pdbe.org/2ome PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [https://www.ebi.ac.uk/pdbsum/2ome PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ome ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [https://pdbe.org/2ome PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [https://www.ebi.ac.uk/pdbsum/2ome PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ome ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN]] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	+	[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Debreczeni~~, J E]]~~	+	[[Category: Debreczeni JE]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Edwards A]]
-	[[Category: Edwards, A]]	+	[[Category: Guo K]]
-	[[Category: Guo, K]]	+	[[Category: Kavanagh KL]]
-	[[Category: Kavanagh~~, K L~~]]	+	[[Category: Oppermann U]]
-	[[Category: Oppermann, U]]	+	[[Category: Pilka ES]]
-	[[Category: Pilka~~, E S~~]]	+	[[Category: Rojkova A]]
-	[[Category: Rojkova, A]]	+	[[Category: Sundstrom M]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Weigelt J]]
-	[[Category: Sundstrom, M]]	+	[[Category: Von Delft F]]
-	[[Category: Weigelt, J]]	+
-	[[Category: ~~C-terminal binding protein]]~~	+
-	~~[[Category: Ctbp2]]~~	+
-	~~[[Category: Dehydrogenase]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Sgc~~]]	+

OCA at 13:00, 9 June 2021

2021-06-09T13:00:04Z

←Older revision		Revision as of 13:00, 9 June 2021
Line 1:		Line 1:

	==Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)==		==Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)==
-	<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='2ome' size='340' side='right'caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2OME FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OME FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [~~http~~://pdbe.org/2ome PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ome PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ome ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [https://pdbe.org/2ome PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [https://www.ebi.ac.uk/pdbsum/2ome PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ome ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN]] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	+	[[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN]] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2ome_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2ome_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Debreczeni, J E]]		[[Category: Debreczeni, J E]]

OCA at 09:03, 18 October 2017

2017-10-18T09:03:32Z

←Older revision		Revision as of 09:03, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)==		==Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)==
	<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://pdbe.org/2ome PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://pdbe.org/2ome PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ome ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 21:30, 9 February 2016

2016-02-09T21:30:34Z

←Older revision		Revision as of 21:30, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ome ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 02:13, 11 September 2015

2015-09-11T02:13:39Z

←Older revision		Revision as of 02:13, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OME FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OME FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://pdbe.org/2ome PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Debreczeni, J E]]		[[Category: Debreczeni, J E]]

OCA at 09:40, 25 December 2014

2014-12-25T09:40:17Z

←Older revision		Revision as of 09:40, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OME FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OME FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN]] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Debreczeni, J E.]]	+	[[Category: Debreczeni, J E]]
-	[[Category: Delft, F von.]]	+	[[Category: Delft, F von]]
-	[[Category: Edwards, A.]]	+	[[Category: Edwards, A]]
-	[[Category: Guo, K.]]	+	[[Category: Guo, K]]
-	[[Category: Kavanagh, K L.]]	+	[[Category: Kavanagh, K L]]
-	[[Category: Oppermann, U.]]	+	[[Category: Oppermann, U]]
-	[[Category: Pilka, E S.]]	+	[[Category: Pilka, E S]]
-	[[Category: Rojkova, A.]]	+	[[Category: Rojkova, A]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Sundstrom, M.]]	+	[[Category: Sundstrom, M]]
-	[[Category: Weigelt, J.]]	+	[[Category: Weigelt, J]]
	[[Category: C-terminal binding protein]]		[[Category: C-terminal binding protein]]
	[[Category: Ctbp2]]		[[Category: Ctbp2]]
Line 37:		Line 39:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomics consortium]]

OCA at 18:33, 30 September 2014

2014-09-30T18:33:35Z

←Older revision		Revision as of 18:33, 30 September 2014
Line 1:		Line 1:
-	~~[[Image:2ome.png\|left\|200px]]~~	+	==Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)==
-		+	<StructureSection load='2ome' size='340' side='right' caption='[[2ome]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{STRUCTURE_2ome\| PDB=2ome \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OME FirstGlance]. <br>
-	===Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ome FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ome OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ome RCSB], [http://www.ebi.ac.uk/pdbsum/2ome PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	<table>
-	[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA].	+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2ome_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]

OCA: Protected "2ome" [edit=sysop:move=sysop]

2013-01-07T13:26:34Z

Protected "2ome" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:26, 7 January 2013

OCA at 13:26, 7 January 2013

2013-01-07T13:26:31Z

←Older revision		Revision as of 13:26, 7 January 2013
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-	{{Seed}}
	[[Image:2ome.png\|left\|200px]]		[[Image:2ome.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2ome", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2ome\| PDB=2ome \| SCENE= }}		{{STRUCTURE_2ome\| PDB=2ome \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2OME~~ is a 8 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA].	+	[[2ome]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA].
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]
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	[[Category: Ctbp2]]		[[Category: Ctbp2]]
	[[Category: Dehydrogenase]]		[[Category: Dehydrogenase]]
		+	[[Category: Oxidoreductase]]
	[[Category: Sgc]]		[[Category: Sgc]]
	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:53:52 2009''

OCA at 10:53, 17 February 2009

2009-02-17T10:53:53Z

←Older revision		Revision as of 10:53, 17 February 2009
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-	[[Image:2ome.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2ome.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2ome\| PDB=2ome \| SCENE= }}		{{STRUCTURE_2ome\| PDB=2ome \| SCENE= }}

-	~~'''~~Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)~~'''~~	+	===Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H)===


	==About this Structure==		==About this Structure==
-	2OME is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA].	+	2OME is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OME OCA].
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Single protein]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]
	[[Category: Debreczeni, J E.]]		[[Category: Debreczeni, J E.]]
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	[[Category: Sgc]]		[[Category: Sgc]]
	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 11:~~12:~~38 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:53:52 2009''