2osr - Revision history

OCA at 09:42, 22 May 2024

2024-05-22T09:42:48Z

←Older revision		Revision as of 09:42, 22 May 2024
Line 1:		Line 1:

	==NMR Structure of RRM-2 of Yeast NPL3 Protein==		==NMR Structure of RRM-2 of Yeast NPL3 Protein==
-	<StructureSection load='2osr' size='340' side='right'caption='[[2osr~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2osr' size='340' side='right'caption='[[2osr]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OSR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OSR FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2osq\|2osq]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [https://pdbe.org/2osr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [https://www.ebi.ac.uk/pdbsum/2osr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2osr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [https://pdbe.org/2osr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [https://www.ebi.ac.uk/pdbsum/2osr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2osr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NOP3_YEAST NOP3_YEAST]] Required for pre-rRNA processing and nuclear import as well as mitochondrial protein targeting. Binds to poly(A).	+	[https://www.uniprot.org/uniprot/NOP3_YEAST NOP3_YEAST] Required for pre-rRNA processing and nuclear import as well as mitochondrial protein targeting. Binds to poly(A).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Allain~~, F H~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Bucheli, M]]	+	[[Category: Allain FH]]
-	[[Category: Buratowski, S]]	+	[[Category: Bucheli M]]
-	[[Category: Deka, P]]	+	[[Category: Buratowski S]]
-	[[Category: Moore, C]]	+	[[Category: Deka P]]
-	[[Category: Skrisovska, L]]	+	[[Category: Moore C]]
-	[[Category: Varani, G]]	+	[[Category: Skrisovska L]]
-	~~[[Category: Mrna]]~~	+	[[Category: Varani G]]
-	~~[[Category: Npl3]]~~	+
-	~~[[Category: Rna binding protein]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rrm]]~~	+
-	~~[[Category: Sr protein~~]]	+

OCA at 13:04, 9 June 2021

2021-06-09T13:04:58Z

←Older revision		Revision as of 13:04, 9 June 2021
Line 1:		Line 1:

	==NMR Structure of RRM-2 of Yeast NPL3 Protein==		==NMR Structure of RRM-2 of Yeast NPL3 Protein==
-	<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2osr' size='340' side='right'caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2OSR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OSR FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2osq\|2osq]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [~~http~~://pdbe.org/2osr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2osr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2osr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [https://pdbe.org/2osr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [https://www.ebi.ac.uk/pdbsum/2osr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2osr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NOP3_YEAST NOP3_YEAST]] Required for pre-rRNA processing and nuclear import as well as mitochondrial protein targeting. Binds to poly(A).	+	[[https://www.uniprot.org/uniprot/NOP3_YEAST NOP3_YEAST]] Required for pre-rRNA processing and nuclear import as well as mitochondrial protein targeting. Binds to poly(A).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Allain, F H]]		[[Category: Allain, F H]]
	[[Category: Bucheli, M]]		[[Category: Bucheli, M]]

OCA at 07:24, 22 August 2018

2018-08-22T07:24:47Z

←Older revision		Revision as of 07:24, 22 August 2018
Line 1:		Line 1:
		+
	==NMR Structure of RRM-2 of Yeast NPL3 Protein==		==NMR Structure of RRM-2 of Yeast NPL3 Protein==
	<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://pdbe.org/2osr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://pdbe.org/2osr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2osr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2osr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2osr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2osr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:58, 11 September 2015

2015-09-11T10:58:07Z

←Older revision		Revision as of 10:58, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSR FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://pdbe.org/2osr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2osr" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Allain, F H]]		[[Category: Allain, F H]]
	[[Category: Bucheli, M]]		[[Category: Bucheli, M]]

OCA at 15:31, 25 December 2014

2014-12-25T15:31:48Z

←Older revision		Revision as of 15:31, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSR FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NOP3_YEAST NOP3_YEAST]] Required for pre-rRNA processing and nuclear import as well as mitochondrial protein targeting. Binds to poly(A).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Allain, F H.]]	+	[[Category: Allain, F H]]
-	[[Category: Bucheli, M.]]	+	[[Category: Bucheli, M]]
-	[[Category: Buratowski, S.]]	+	[[Category: Buratowski, S]]
-	[[Category: Deka, P.]]	+	[[Category: Deka, P]]
-	[[Category: Moore, C.]]	+	[[Category: Moore, C]]
-	[[Category: Skrisovska, L.]]	+	[[Category: Skrisovska, L]]
-	[[Category: Varani, G.]]	+	[[Category: Varani, G]]
	[[Category: Mrna]]		[[Category: Mrna]]
	[[Category: Npl3]]		[[Category: Npl3]]

OCA at 18:25, 30 September 2014

2014-09-30T18:25:40Z

←Older revision		Revision as of 18:25, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2osr.~~png~~\|~~left~~\|200px]]	+	==NMR Structure of RRM-2 of Yeast NPL3 Protein==
		+	<StructureSection load='2osr' size='340' side='right' caption='[[2osr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OSR FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osq\|2osq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP3, MTS1, NAB1, NPL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2osr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2osr RCSB], [http://www.ebi.ac.uk/pdbsum/2osr PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2osr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Yeast Npl3 is homologous to SR proteins in higher eukaryotes, a family of RNA-binding proteins that have multiple essential roles in RNA metabolism. This protein competes with 3'-end processing factors for binding to the nascent RNA, protecting the transcript from premature termination and coordinating transcription termination and the packaging of the fully processed transcript for export. The NMR structure of its RNA-binding domain shows two unusually compact RNA recognition motifs (RRMs), and identifies the RNA recognition surface in Npl3. Biochemical and NMR studies identify a class of G+U-rich RNA sequences with high specificity for this protein. The protein binds to RNA and forms a single globular structure, but the two RRMs of Npl3 are not equivalent, with the second domain forming much stronger interactions with G+U-rich RNA sequences that occur independently of the interaction of the first RRM. The specific binding to G+U-rich RNAs observed for the two RRMs of Npl3 is masked in the full-length protein by a much stronger but non-sequence-specific RNA-binding activity residing outside of its RRMs. The preference of Npl3 for G+U-rich sequences supports the model for its function in regulating recognition of 3'-end processing sites through competition with the Rna15 (yeast analog of human CstF-64 protein) subunit of the processing complex.

-	~~{{STRUCTURE_2osr\| PDB=2osr \| SCENE= }}~~	+	Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.,Deka P, Bucheli ME, Moore C, Buratowski S, Varani G J Mol Biol. 2008 Jan 4;375(1):136-50. Epub 2007 Sep 16. PMID:18022637<ref>PMID:18022637</ref>

-	~~===NMR Structure~~ of ~~RRM-2 of Yeast NPL3 Protein===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18022637}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2osr]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018022637<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Allain, F H.]]		[[Category: Allain, F H.]]

OCA: Protected "2osr" [edit=sysop:move=sysop]

2013-01-07T10:41:01Z

Protected "2osr" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:41, 7 January 2013

OCA at 10:40, 7 January 2013

2013-01-07T10:40:59Z

←Older revision		Revision as of 10:40, 7 January 2013
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-	{{Seed}}
	[[Image:2osr.png\|left\|200px]]		[[Image:2osr.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2osr", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2osr\| PDB=2osr \| SCENE= }}		{{STRUCTURE_2osr\| PDB=2osr \| SCENE= }}

	===NMR Structure of RRM-2 of Yeast NPL3 Protein===		===NMR Structure of RRM-2 of Yeast NPL3 Protein===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18022637}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18022637 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_18022637}}		{{ABSTRACT_PUBMED_18022637}}

	==About this Structure==		==About this Structure==
-	~~2OSR~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].	+	[[2osr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18022637~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018022637</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Allain, F H.]]		[[Category: Allain, F H.]]
Line 38:		Line 26:
	[[Category: Rrm]]		[[Category: Rrm]]
	[[Category: Sr protein]]		[[Category: Sr protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:26:16 2009''

OCA at 18:26, 17 February 2009

2009-02-17T18:26:17Z

←Older revision		Revision as of 18:26, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2OSR is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].	+	2OSR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].

	==Reference==		==Reference==
-	Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals., Deka P, Bucheli ME, Moore C, Buratowski S, Varani G, J Mol Biol. 2008 Jan 4;375(1):136-50. Epub 2007 Sep 16. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18022637 18022637]~~	+	<ref group="xtra">PMID:18022637</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Single protein]]
	[[Category: Allain, F H.]]		[[Category: Allain, F H.]]
	[[Category: Bucheli, M.]]		[[Category: Bucheli, M.]]
Line 40:		Line 39:
	[[Category: Sr protein]]		[[Category: Sr protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 04:~~20:~~28 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:26:16 2009''

OCA at 01:20, 29 July 2008

2008-07-29T01:20:33Z

←Older revision		Revision as of 01:20, 29 July 2008
Line 1:		Line 1:
-	[[Image:2osr.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2osr.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2osr\| PDB=2osr \| SCENE= }}		{{STRUCTURE_2osr\| PDB=2osr \| SCENE= }}

-	~~'''~~NMR Structure of RRM-2 of Yeast NPL3 Protein~~'''~~	+	===NMR Structure of RRM-2 of Yeast NPL3 Protein===


-	~~==Overview==~~	+	<!--
-	~~Yeast Npl3 is homologous to SR proteins in higher eukaryotes, a family of RNA~~-~~binding proteins that have multiple essential roles in RNA metabolism. This protein competes with 3'~~-~~end processing factors for binding to the nascent RNA~~, ~~protecting~~ the ~~transcript from premature termination and coordinating transcription termination and~~ the ~~packaging of the fully processed transcript for export. The NMR structure of its RNA-binding domain shows two unusually compact RNA recognition motifs~~ (~~RRMs), and identifies the RNA recognition surface in Npl3~~. ~~Biochemical and NMR studies identify a class of G+U-rich RNA sequences with high specificity for this protein~~. ~~The protein binds to RNA and forms a single globular structure~~, but the two RRMs of Npl3 are not equivalent, with the second domain forming much stronger interactions with G+U-rich RNA sequences that occur independently of the interaction of the first RRM. The specific binding to G+U-rich RNAs observed for the two RRMs of Npl3 is ~~masked in~~ the ~~full-length protein by a much stronger but non-sequence-specific RNA-binding activity residing outside of its RRMs~~. ~~The preference of Npl3 for G+U~~-~~rich sequences supports the model for its function in regulating recognition of 3'~~-~~end processing sites through competition with the Rna15 (yeast analog of human CstF-64 protein) subunit of the processing complex.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_18022637}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18022637 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18022637}}

	==About this Structure==		==About this Structure==
-	2OSR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].	+	2OSR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSR OCA].

	==Reference==		==Reference==
Line 35:		Line 39:
	[[Category: Rrm]]		[[Category: Rrm]]
	[[Category: Sr protein]]		[[Category: Sr protein]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 11~~:35:02 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:20:28 2008''