2pal - Revision history

OCA at 07:44, 9 March 2022

2022-03-09T07:44:16Z

←Older revision		Revision as of 07:44, 9 March 2022
Line 3:		Line 3:
	<StructureSection load='2pal' size='340' side='right'caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pal' size='340' side='right'caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Esolu Esolu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2PAL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Esolu Esolu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PAL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [~~http~~://pdbe.org/2pal PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pal PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pal ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [https://pdbe.org/2pal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [https://www.ebi.ac.uk/pdbsum/2pal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pal ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.	+	[[https://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:53, 3 June 2020

2020-06-03T06:53:30Z

←Older revision		Revision as of 06:53, 3 June 2020
Line 1:		Line 1:

	==IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS==		==IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS==
-	<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2pal' size='340' side='right'caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esolu Esolu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PAL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esolu Esolu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PAL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://pdbe.org/2pal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pal ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://pdbe.org/2pal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pal ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Esolu]]		[[Category: Esolu]]
		+	[[Category: Large Structures]]
	[[Category: Declercq, J P]]		[[Category: Declercq, J P]]
	[[Category: Parello, J]]		[[Category: Parello, J]]

OCA at 08:53, 29 August 2018

2018-08-29T08:53:42Z

←Older revision		Revision as of 08:53, 29 August 2018
Line 1:		Line 1:
		+
	==IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS==		==IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS==
	<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://pdbe.org/2pal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://pdbe.org/2pal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pal ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pal_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pal_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pal ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:47, 11 September 2015

2015-09-11T08:47:44Z

←Older revision		Revision as of 08:47, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Esox_lucius Esox lucius~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PAL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esolu Esolu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PAL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://pdbe.org/2pal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2pal" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Esox lucius~~]]	+	[[Category: Esolu]]
	[[Category: Declercq, J P]]		[[Category: Declercq, J P]]
	[[Category: Parello, J]]		[[Category: Parello, J]]

OCA at 14:03, 25 December 2014

2014-12-25T14:03:48Z

←Older revision		Revision as of 14:03, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PAL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PAL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
-	[[Category: Declercq, J P.]]	+	[[Category: Declercq, J P]]
-	[[Category: Parello, J.]]	+	[[Category: Parello, J]]
-	[[Category: Rambaud, J.]]	+	[[Category: Rambaud, J]]
-	[[Category: Tinant, B.]]	+	[[Category: Tinant, B]]
	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]

OCA at 08:01, 29 September 2014

2014-09-29T08:01:40Z

←Older revision		Revision as of 08:01, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2pal.~~png~~\|~~left~~\|200px]]	+	==IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS==
		+	<StructureSection load='2pal' size='340' side='right' caption='[[2pal]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PAL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pal RCSB], [http://www.ebi.ac.uk/pdbsum/2pal PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pal_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of the Ca-loaded form of pike 4.10 parvalbumin (minor component from pike muscle belonging to the beta phylogenetic series), with both its primary sites CD and EF occupied by Ca2+ ions and its third site occupied by an ammonium ion, as previously determined at 1.93 A resolution, has now been refined to a resolution of 1.65 A. The crystallization of this parvalbumin in different ionic environments has allowed three novel non-isomorphous crystalline forms to be obtained: (1) a first form, crystallized in the presence of a mixture of ammonium sulphate and manganese sulphate, for which all the cation binding sites in the protein are occupied by Mn2+; (2) a second form crystallized in the presence of MgSO4 as the precipitating agent, only differs from the Ca/NH4 form by the occupation of the third site by Mg2+, whereas the primary sites remain occupied by Ca2+; (3) a third form, also crystallized in the presence of MgSO4, corresponds to a well-defined molecular species with both the primary EF site and the third site occupied by Mg2+, whereas the primary CD site remains occupied by CA2+. The corresponding molecular structures reported here have been determined at resolutions between 1.8 and 2.4 A. The comparison of the different crystal structures allows the structural modifications accompanying the substitution of the primary sites by cations differing significantly in their ionic radii (Ca2+, Mn2+, Mg2+) to be investigated in detail, and it also leads to a precise description of the third site in a typical beta parvalbumin. The substitution Ca2+ by Mg2+ within the primary site EF is characterized by a "contraction" of the co-ordination sphere, with a decrease of the mean oxygen-metal distance by a value of 0.25 A and a decrease of the co-ordination number from 7 to 6, as a consequence of the loss of a bidentate ligand (Glu101), which becomes a monodentate one. Such an adaptation of the co-ordination sphere around a cation of smaller size involves, among others, the transformation of the Glu101 side-chain from the stable gauche(+) form to the less stable gauche(-) form. The third site is clearly described as a satellite of the CD primary site, since both sites possess common protein ligands, such as Asp53 and Glu59. Furthermore, Asp61 appears as a specific ligand of the third site in the different environments investigated in this work. We finally discuss the relevance of the third site to parvalbumin phylogeny.

-	~~{{STRUCTURE_2pal\| PDB=2pal \| SCENE= }}~~	+	Ionic interactions with parvalbumins. Crystal structure determination of pike 4.10 parvalbumin in four different ionic environments.,Declercq JP, Tinant B, Parello J, Rambaud J J Mol Biol. 1991 Aug 20;220(4):1017-39. PMID:1880797<ref>PMID:1880797</ref>

-	~~===IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_1880797}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2pal]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Esox_lucius Esox lucius]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].~~	+

	==See Also==		==See Also==
	*[[Parvalbumin\|Parvalbumin]]		*[[Parvalbumin\|Parvalbumin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:001880797<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
	[[Category: Declercq, J P.]]		[[Category: Declercq, J P.]]

OCA at 17:35, 20 October 2012

2012-10-20T17:35:40Z

←Older revision		Revision as of 17:35, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2pal]] is a 1 chain structure ~~of [[Parvalbumin]]~~ with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].	+	[[2pal]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].

	==See Also==		==See Also==

OCA: Protected "2pal" [edit=sysop:move=sysop]

2012-07-27T01:25:35Z

Protected "2pal" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:25, 27 July 2012

OCA at 01:25, 27 July 2012

2012-07-27T01:25:34Z

←Older revision		Revision as of 01:25, 27 July 2012
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-	{{Seed}}
	[[Image:2pal.png\|left\|200px]]		[[Image:2pal.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2pal", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2pal\| PDB=2pal \| SCENE= }}		{{STRUCTURE_2pal\| PDB=2pal \| SCENE= }}

	===IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS===		===IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_1880797}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 1880797 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_1880797}}		{{ABSTRACT_PUBMED_1880797}}

	==About this Structure==		==About this Structure==
-	~~2PAL~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].	+	[[2pal]] is a 1 chain structure of [[Parvalbumin]] with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].
		+
		+	==See Also==
		+	*[[Parvalbumin\|Parvalbumin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~1880797~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:001880797</ref><references group="xtra"/>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
	[[Category: Declercq, J P.]]		[[Category: Declercq, J P.]]
Line 30:		Line 21:
	[[Category: Tinant, B.]]		[[Category: Tinant, B.]]
	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:11:21 2009''

OCA at 16:11, 17 February 2009

2009-02-17T16:11:22Z

←Older revision		Revision as of 16:11, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2PAL is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].	+	2PAL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PAL OCA].

	==Reference==		==Reference==
-	Ionic interactions with parvalbumins. Crystal structure determination of pike 4.10 parvalbumin in four different ionic environments., Declercq JP, Tinant B, Parello J, Rambaud J, J Mol Biol. 1991 Aug 20;220(4):1017-39. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/1880797 1880797]~~	+	<ref group="xtra">PMID:1880797</ref><references group="xtra"/>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
-	[[Category: Single protein]]
	[[Category: Declercq, J P.]]		[[Category: Declercq, J P.]]
	[[Category: Parello, J.]]		[[Category: Parello, J.]]
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	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 01~~:48:~~30 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:11:21 2009''