2poa - Revision history

OCA at 18:27, 20 October 2021

2021-10-20T18:27:33Z

←Older revision		Revision as of 18:27, 20 October 2021
Line 3:		Line 3:
	<StructureSection load='2poa' size='340' side='right'caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2poa' size='340' side='right'caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2POA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [~~http~~://pdbe.org/2poa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2poa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2poa ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [https://pdbe.org/2poa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [https://www.ebi.ac.uk/pdbsum/2poa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FABP_SCHMA FABP_SCHMA]] May play a role in the transport of fatty acids. Binds various fatty acids, such as arachidonic, oleic, palmitic and linolenic acid (in vitro).	+	[[https://www.uniprot.org/uniprot/FABP_SCHMA FABP_SCHMA]] May play a role in the transport of fatty acids. Binds various fatty acids, such as arachidonic, oleic, palmitic and linolenic acid (in vitro).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:34, 5 February 2020

2020-02-05T08:34:58Z

←Older revision		Revision as of 08:34, 5 February 2020
Line 1:		Line 1:

	==Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue==		==Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue==
-	<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>	+	<StructureSection load='2poa' size='340' side='right'caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]	+	*[[Fatty acid-binding protein 3D structures\|Fatty acid-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Blood fluke]]		[[Category: Blood fluke]]
		+	[[Category: Large Structures]]
	[[Category: Ho, P L]]		[[Category: Ho, P L]]
	[[Category: Oyama, S]]		[[Category: Oyama, S]]

OCA at 08:18, 29 August 2018

2018-08-29T08:18:24Z

←Older revision		Revision as of 08:18, 29 August 2018
Line 1:		Line 1:
		+
	==Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue==		==Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue==
	<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://pdbe.org/2poa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://pdbe.org/2poa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2poa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 10:42, 8 February 2016

2016-02-08T10:42:41Z

←Older revision		Revision as of 10:42, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:45, 10 September 2015

2015-09-10T10:45:59Z

←Older revision		Revision as of 10:45, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schistosoma_mansoni Schistosoma mansoni~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://pdbe.org/2poa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2poa" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Schistosoma mansoni~~]]	+	[[Category: Blood fluke]]
	[[Category: Ho, P L]]		[[Category: Ho, P L]]
	[[Category: Oyama, S]]		[[Category: Oyama, S]]
Line 43:		Line 44:
	[[Category: Molecular dynamic]]		[[Category: Molecular dynamic]]
	[[Category: Protein stability]]		[[Category: Protein stability]]
		+	[[Category: Schistosoma mansoni]]
	[[Category: Site directed mutagenesis]]		[[Category: Site directed mutagenesis]]
	[[Category: Vaccine antigen]]		[[Category: Vaccine antigen]]

OCA at 22:45, 24 December 2014

2014-12-24T22:45:45Z

←Older revision		Revision as of 22:45, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FABP_SCHMA FABP_SCHMA]] May play a role in the transport of fatty acids. Binds various fatty acids, such as arachidonic, oleic, palmitic and linolenic acid (in vitro).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Schistosoma mansoni]]		[[Category: Schistosoma mansoni]]
-	[[Category: Ho, P L.]]	+	[[Category: Ho, P L]]
-	[[Category: Oyama, S.]]	+	[[Category: Oyama, S]]
-	[[Category: Pertinhez, T A.]]	+	[[Category: Pertinhez, T A]]
-	[[Category: Ramos, C R.R.]]	+	[[Category: Ramos, C R.R]]
-	[[Category: Sforca, M L.]]	+	[[Category: Sforca, M L]]
-	[[Category: Spisni, A.]]	+	[[Category: Spisni, A]]
	[[Category: Fatty acid binding protein]]		[[Category: Fatty acid binding protein]]
	[[Category: Lipid binding protein]]		[[Category: Lipid binding protein]]
	[[Category: Molecular dynamic]]		[[Category: Molecular dynamic]]
	[[Category: Protein stability]]		[[Category: Protein stability]]
-	[[Category: Schistosoma mansoni]]
	[[Category: Site directed mutagenesis]]		[[Category: Site directed mutagenesis]]
	[[Category: Vaccine antigen]]		[[Category: Vaccine antigen]]

OCA at 07:19, 29 September 2014

2014-09-29T07:19:01Z

←Older revision		Revision as of 07:19, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2poa.~~png\|left~~\|200px]]	+	==Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue==
		+	<StructureSection load='2poa' size='340' side='right' caption='[[2poa]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2POA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2poa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2poa RCSB], [http://www.ebi.ac.uk/pdbsum/2poa PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Schistosoma mansoni fatty acid binding protein (FABP), Sm14, is a vaccine candidate against, S. mansoni and F. hepatica. Previously, we demonstrated the importance of a correct fold to achieve protection in immunized animals after cercariae challenge [[10]. C.R.R. Ramos, R.C.R. Figueredo, T.A. Pertinhez, M.M. Vilar, A.L.T.O. Nascimento, M. Tendler, I. Raw, A. Spisni, P.L. Ho, Gene structure and M20T polymorphism of the Schistosoma mansoni Sm14 fatty acid-binding protein: structural, functional and immunoprotection analysis. J. Biol. Chem. 278 (2003) 12745-12751.]. Here we show that the reduction of vaccine efficacy over time is due to protein dimerization and subsequent aggregation. We produced the mutants Sm14-M20(C62S) and Sm14-M20(C62V) that, as expected, did not dimerize in SDS-PAGE. Molecular dynamics calculations and unfolding experiments highlighted a higher structural stability of these mutants with respect to the wild-type. In addition, we found that the mutated proteins, after thermal denaturation, refolded to their active native molecular architecture as proved by the recovery of the fatty acid binding ability. Sm14-M20(C62V) turned out to be the more stable form over time, providing the basis to determine the first 3D solution structure of a Sm14 protein in its apo-form. Overall, Sm14-M20(C62V) possesses an improved structural stability over time, an essential feature to preserve its immunization capability and, in experimentally immunized animals, it exhibits a protection effect against S. mansoni cercariae infections comparable to the one obtained with the wild-type protein. These facts indicate this protein as a good lead molecule for large-scale production and for developing an effective Sm14 based anti-helminthes vaccine.

-	~~{{STRUCTURE_2poa\| PDB=2poa \| SCENE= }}~~	+	Stability improvement of the fatty acid binding protein Sm14 from S. mansoni by Cys replacement: structural and functional characterization of a vaccine candidate.,Ramos CR, Spisni A, Oyama S Jr, Sforca ML, Ramos HR, Vilar MM, Alves AC, Figueredo RC, Tendler M, Zanchin NI, Pertinhez TA, Ho PL Biochim Biophys Acta. 2009 Apr;1794(4):655-62. Epub 2008 Dec 25. PMID:19150418<ref>PMID:19150418</ref>

-	~~===Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution~~ of the ~~single Cys62 residue===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19150418}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2poa]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Schistosoma_mansoni Schistosoma mansoni]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA].~~	+

	==See Also==		==See Also==
	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]		*[[Fatty acid-binding protein\|Fatty acid-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019150418<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Schistosoma mansoni]]		[[Category: Schistosoma mansoni]]
	[[Category: Ho, P L.]]		[[Category: Ho, P L.]]

OCA at 09:53, 20 October 2012

2012-10-20T09:53:45Z

←Older revision		Revision as of 09:53, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2poa]] is a 1 chain structure ~~of [[Fatty acid-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA].	+	[[2poa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA].

	==See Also==		==See Also==

OCA: Protected "2poa" [edit=sysop:move=sysop]

2012-07-26T00:18:15Z

Protected "2poa" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:18, 26 July 2012

OCA at 00:18, 26 July 2012

2012-07-26T00:18:14Z

←Older revision		Revision as of 00:18, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2poa.png\|left\|200px]]		[[Image:2poa.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2poa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2poa\| PDB=2poa \| SCENE= }}		{{STRUCTURE_2poa\| PDB=2poa \| SCENE= }}

	===Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue===		===Schistosoma mansoni Sm14 Fatty Acid-Binding Protein: improvement of protein stability by substitution of the single Cys62 residue===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19150418}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19150418 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19150418}}		{{ABSTRACT_PUBMED_19150418}}

	==About this Structure==		==About this Structure==
-	~~2POA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA].	+	[[2poa]] is a 1 chain structure of [[Fatty acid-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POA OCA].
		+
		+	==See Also==
		+	*[[Fatty acid-binding protein\|Fatty acid-binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19150418~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019150418</ref><references group="xtra"/>
	[[Category: Schistosoma mansoni]]		[[Category: Schistosoma mansoni]]
	[[Category: Ho, P L.]]		[[Category: Ho, P L.]]
-	[[Category: ~~Jr.~~, S ~~Oyama~~.]]	+	[[Category: Oyama, S.]]
	[[Category: Pertinhez, T A.]]		[[Category: Pertinhez, T A.]]
	[[Category: Ramos, C R.R.]]		[[Category: Ramos, C R.R.]]
Line 38:		Line 29:
	[[Category: Site directed mutagenesis]]		[[Category: Site directed mutagenesis]]
	[[Category: Vaccine antigen]]		[[Category: Vaccine antigen]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 10:43:38 2009''