2pst - Revision history

OCA at 09:11, 21 February 2024

2024-02-21T09:11:48Z

←Older revision		Revision as of 09:11, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='2pst' size='340' side='right'caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pst' size='340' side='right'caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PST FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PST FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2gpf~~\|~~2gpf~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [https://pdbe.org/2pst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [https://www.ebi.ac.uk/pdbsum/2pst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pst ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [https://pdbe.org/2pst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [https://www.ebi.ac.uk/pdbsum/2pst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pst ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9I169_PSEAE Q9I169_PSEAE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pst ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pst ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Many bacteria use nonribosomal peptide synthetase (NRPS) proteins to produce peptide antibiotics and siderophores. The catalytic domains of the NRPS proteins are usually linked in large multidomain proteins. Often, additional proteins are coexpressed with NRPS proteins that modify the NRPS peptide products, ensure the availability of substrate building blocks, or play a role in the import or export of the NRPS product. Many NRPS clusters include a small protein of approximately 80 amino acids with homology to the MbtH protein of mycobactin synthesis in Mycobacteria tuberculosis; no function has been assigned to these proteins. Pseudomonas aeruginosa utilizes an NRPS cluster to synthesize the siderophore pyoverdine. The pyoverdine peptide contains a dihydroxyquinoline-based chromophore, as well as two formyl-N-hydroxyornithine residues, which are involved in iron binding. The pyoverdine cluster contains four modular NRPS enzymes and 10-15 additional proteins that are essential for pyoverdine production. Coexpressed with the pyoverdine synthetic enzymes is a 72-amino acid MbtH-like family member designated PA2412. We have determined the three-dimensional structure of the PA2412 protein and describe here the structure and the location of conserved regions. Additionally, we have further analyzed a deletion mutant of the PA2412 protein for growth and pyoverdine production. Our results demonstrate that PA2412 is necessary for the production or secretion of pyoverdine at normal levels. The PA2412 deletion strain is able to use exogenously produced pyoverdine, showing that there is no defect in the uptake or utilization of the iron-pyoverdine complex.
-
-	The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.,Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM J Biol Chem. 2007 Jul 13;282(28):20425-34. Epub 2007 May 14. PMID:17502378<ref>PMID:17502378</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2pst" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Drake~~, E J~~]]	+	[[Category: Drake EJ]]
-	[[Category: Gulick~~, A M~~]]	+	[[Category: Gulick AM]]
-	[[Category: Shah~~, M B]]~~	+	[[Category: Shah MB]]
-	~~[[Category: Cog3251]]~~	+
-	~~[[Category: Mbth-like family]]~~	+
-	~~[[Category: Non-ribosomal peptide synthesis cluster]]~~	+
-	~~[[Category: Pyoverdine synthesis]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 15:32, 17 June 2021

2021-06-17T15:32:05Z

←Older revision		Revision as of 15:32, 17 June 2021
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	<StructureSection load='2pst' size='340' side='right'caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pst' size='340' side='right'caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PST FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PST FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gpf\|2gpf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [~~http~~://pdbe.org/2pst PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pst PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pst ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [https://pdbe.org/2pst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [https://www.ebi.ac.uk/pdbsum/2pst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pst ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:40, 31 July 2019

2019-07-31T07:40:43Z

←Older revision		Revision as of 07:40, 31 July 2019
Line 1:		Line 1:

	==1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa==		==1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa==
-	<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2pst' size='340' side='right'caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2pst_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2pst_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pseae]]		[[Category: Pseae]]
	[[Category: Drake, E J]]		[[Category: Drake, E J]]

OCA at 09:32, 18 October 2017

2017-10-18T09:32:40Z

←Older revision		Revision as of 09:32, 18 October 2017
Line 1:		Line 1:
		+
	==1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa==		==1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa==
	<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://pdbe.org/2pst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://pdbe.org/2pst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pst ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pst ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:15, 11 September 2015

2015-09-11T12:15:25Z

←Older revision		Revision as of 12:15, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://pdbe.org/2pst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2pst" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas aeruginosa pao1~~]]	+	[[Category: Pseae]]
	[[Category: Drake, E J]]		[[Category: Drake, E J]]
	[[Category: Gulick, A M]]		[[Category: Gulick, A M]]

OCA at 16:19, 25 December 2014

2014-12-25T16:19:17Z

←Older revision		Revision as of 16:19, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas aeruginosa pao1]]		[[Category: Pseudomonas aeruginosa pao1]]
-	[[Category: Drake, E J.]]	+	[[Category: Drake, E J]]
-	[[Category: Gulick, A M.]]	+	[[Category: Gulick, A M]]
-	[[Category: Shah, M B.]]	+	[[Category: Shah, M B]]
	[[Category: Cog3251]]		[[Category: Cog3251]]
	[[Category: Mbth-like family]]		[[Category: Mbth-like family]]

OCA at 19:28, 30 September 2014

2014-09-30T19:28:12Z

←Older revision		Revision as of 19:28, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2pst.~~png~~\|~~left~~\|200px]]	+	==1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa==
		+	<StructureSection load='2pst' size='340' side='right' caption='[[2pst]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PST FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gpf\|2gpf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pst RCSB], [http://www.ebi.ac.uk/pdbsum/2pst PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2pst_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Many bacteria use nonribosomal peptide synthetase (NRPS) proteins to produce peptide antibiotics and siderophores. The catalytic domains of the NRPS proteins are usually linked in large multidomain proteins. Often, additional proteins are coexpressed with NRPS proteins that modify the NRPS peptide products, ensure the availability of substrate building blocks, or play a role in the import or export of the NRPS product. Many NRPS clusters include a small protein of approximately 80 amino acids with homology to the MbtH protein of mycobactin synthesis in Mycobacteria tuberculosis; no function has been assigned to these proteins. Pseudomonas aeruginosa utilizes an NRPS cluster to synthesize the siderophore pyoverdine. The pyoverdine peptide contains a dihydroxyquinoline-based chromophore, as well as two formyl-N-hydroxyornithine residues, which are involved in iron binding. The pyoverdine cluster contains four modular NRPS enzymes and 10-15 additional proteins that are essential for pyoverdine production. Coexpressed with the pyoverdine synthetic enzymes is a 72-amino acid MbtH-like family member designated PA2412. We have determined the three-dimensional structure of the PA2412 protein and describe here the structure and the location of conserved regions. Additionally, we have further analyzed a deletion mutant of the PA2412 protein for growth and pyoverdine production. Our results demonstrate that PA2412 is necessary for the production or secretion of pyoverdine at normal levels. The PA2412 deletion strain is able to use exogenously produced pyoverdine, showing that there is no defect in the uptake or utilization of the iron-pyoverdine complex.

-	~~{{STRUCTURE_2pst\| PDB=2pst \| SCENE= }}~~	+	The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.,Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM J Biol Chem. 2007 Jul 13;282(28):20425-34. Epub 2007 May 14. PMID:17502378<ref>PMID:17502378</ref>

-	~~===1.8A Crystal Structure~~ of the ~~PA2412 protein from Pseudomonas aeruginosa===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17502378}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2pst]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017502378<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pseudomonas aeruginosa pao1]]		[[Category: Pseudomonas aeruginosa pao1]]
	[[Category: Drake, E J.]]		[[Category: Drake, E J.]]

OCA: Protected "2pst" [edit=sysop:move=sysop]

2013-01-07T11:49:21Z

Protected "2pst" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:49, 7 January 2013

OCA at 11:49, 7 January 2013

2013-01-07T11:49:19Z

←Older revision		Revision as of 11:49, 7 January 2013
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-	{{Seed}}
	[[Image:2pst.png\|left\|200px]]		[[Image:2pst.png\|left\|200px]]

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	{{STRUCTURE_2pst\| PDB=2pst \| SCENE= }}		{{STRUCTURE_2pst\| PDB=2pst \| SCENE= }}

	===1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa===		===1.8A Crystal Structure of the PA2412 protein from Pseudomonas aeruginosa===

-
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	{{ABSTRACT_PUBMED_17502378}}		{{ABSTRACT_PUBMED_17502378}}

	==About this Structure==		==About this Structure==
-	~~2PST~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa~~ Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA].	+	[[2pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17502378~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017502378</ref><references group="xtra"/>
-	[[Category: Pseudomonas aeruginosa]]	+	[[Category: Pseudomonas aeruginosa pao1]]
	[[Category: Drake, E J.]]		[[Category: Drake, E J.]]
	[[Category: Gulick, A M.]]		[[Category: Gulick, A M.]]
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	[[Category: Non-ribosomal peptide synthesis cluster]]		[[Category: Non-ribosomal peptide synthesis cluster]]
	[[Category: Pyoverdine synthesis]]		[[Category: Pyoverdine synthesis]]
-		+	[[Category: Unknown function]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 21:34:15 2009''~~	+

OCA at 19:34, 17 February 2009

2009-02-17T19:34:16Z

←Older revision		Revision as of 19:34, 17 February 2009
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	==About this Structure==		==About this Structure==
-	2PST is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA].	+	2PST is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PST OCA].

	==Reference==		==Reference==
-	The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa., Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM, J Biol Chem. 2007 Jul 13;282(28):20425-34. Epub 2007 May 14. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17502378 17502378]~~	+	<ref group="xtra">PMID:17502378</ref><references group="xtra"/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Single protein]]
	[[Category: Drake, E J.]]		[[Category: Drake, E J.]]
	[[Category: Gulick, A M.]]		[[Category: Gulick, A M.]]
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	[[Category: Pyoverdine synthesis]]		[[Category: Pyoverdine synthesis]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 05~~:42:~~20 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:34:15 2009''