2pu9 - Revision history

OCA at 18:29, 20 October 2021

2021-10-20T18:29:31Z

←Older revision		Revision as of 18:29, 20 October 2021
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	<StructureSection load='2pu9' size='340' side='right'caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2pu9' size='340' side='right'caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Cyanobacterium_synechocystis Cyanobacterium synechocystis~~] and [https://en.wikipedia.org/wiki/~~Spiol Spiol~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Spiol Spiol] and [https://en.wikipedia.org/wiki/Synechocystis_sp Synechocystis sp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 ~~Cyanobacterium synechocystis~~]), ftrV ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 ~~Cyanobacterium synechocystis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp]), ftrV ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [https://pdbe.org/2pu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [https://www.ebi.ac.uk/pdbsum/2pu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [https://pdbe.org/2pu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [https://www.ebi.ac.uk/pdbsum/2pu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu9 ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cyanobacterium synechocystis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Spiol]]		[[Category: Spiol]]
		+	[[Category: Synechocystis sp]]
	[[Category: Dai, S]]		[[Category: Dai, S]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 15:32, 17 June 2021

2021-06-17T15:32:52Z

←Older revision		Revision as of 15:32, 17 June 2021
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	==Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f==		==Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f==
-	<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='2pu9' size='340' side='right'caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cyanobacterium_synechocystis Cyanobacterium synechocystis] and [~~http~~://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Cyanobacterium_synechocystis Cyanobacterium synechocystis] and [https://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis]), ftrV ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis]), ftrV ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [~~http~~://pdbe.org/2pu9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pu9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [https://pdbe.org/2pu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [https://www.ebi.ac.uk/pdbsum/2pu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/Q55389_SYNY3 Q55389_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).[PIRNR:PIRNR000260] [[~~http~~://www.uniprot.org/uniprot/TRXF_SPIOL TRXF_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle. [[~~http~~://www.uniprot.org/uniprot/FTRV_SYNY3 FTRV_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).	+	[[https://www.uniprot.org/uniprot/Q55389_SYNY3 Q55389_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).[PIRNR:PIRNR000260] [[https://www.uniprot.org/uniprot/TRXF_SPIOL TRXF_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle. [[https://www.uniprot.org/uniprot/FTRV_SYNY3 FTRV_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/2pu9_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/2pu9_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2pu9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2pu9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ferredoxin thioredoxin reductase\|Ferredoxin thioredoxin reductase]]
		+	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Cyanobacterium synechocystis]]		[[Category: Cyanobacterium synechocystis]]
		+	[[Category: Large Structures]]
	[[Category: Spiol]]		[[Category: Spiol]]
	[[Category: Dai, S]]		[[Category: Dai, S]]

OCA at 09:33, 18 October 2017

2017-10-18T09:33:11Z

←Older revision		Revision as of 09:33, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f==		==Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f==
	<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://pdbe.org/2pu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://pdbe.org/2pu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 2pu9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2pu9" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Ferredoxin thioredoxin reductase\|Ferredoxin thioredoxin reductase]]
-	*[[Thioredoxin\|Thioredoxin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:34, 10 February 2016

2016-02-10T07:34:09Z

←Older revision		Revision as of 07:34, 10 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pu9 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:44, 11 September 2015

2015-09-11T06:44:28Z

←Older revision		Revision as of 06:44, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Spinacia_oleracea Spinacia oleracea~~] and [http://en.wikipedia.org/wiki/~~Synechocystis_sp. Synechocystis sp.~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Cyanobacterium_synechocystis Cyanobacterium synechocystis] and [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 ~~Synechocystis sp.~~]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 ~~Synechocystis sp.~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Cyanobacterium synechocystis])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://pdbe.org/2pu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/TRXF_SPIOL TRXF_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle. [[http://www.uniprot.org/uniprot/FTRV_SYNY3 FTRV_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).	+	[[http://www.uniprot.org/uniprot/Q55389_SYNY3 Q55389_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).[PIRNR:PIRNR000260] [[http://www.uniprot.org/uniprot/TRXF_SPIOL TRXF_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle. [[http://www.uniprot.org/uniprot/FTRV_SYNY3 FTRV_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2pu9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Spinacia oleracea~~]]	+	[[Category: Cyanobacterium synechocystis]]
-	[[Category: ~~Synechocystis sp~~]]	+	[[Category: Spiol]]
	[[Category: Dai, S]]		[[Category: Dai, S]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 12:45, 25 December 2014

2014-12-25T12:45:21Z

←Older revision		Revision as of 12:45, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TRXF_SPIOL TRXF_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The F form is known to activate a number of enzymes of the photosynthetic carbon cycle. [[http://www.uniprot.org/uniprot/FTRV_SYNY3 FTRV_SYNY3]] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Spinacia oleracea]]		[[Category: Spinacia oleracea]]
-	[[Category: Synechocystis sp.]]	+	[[Category: Synechocystis sp]]
-	[[Category: Dai, S.]]	+	[[Category: Dai, S]]
	[[Category: Electron transport]]		[[Category: Electron transport]]
	[[Category: Iron-sulfur]]		[[Category: Iron-sulfur]]

OCA at 09:37, 29 September 2014

2014-09-29T09:37:00Z

←Older revision		Revision as of 09:37, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2pu9.~~png~~\|~~left~~\|200px]]	+	==Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f==
		+	<StructureSection load='2pu9' size='340' side='right' caption='[[2pu9]], [[Resolution\|resolution]] 1.65Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PU9 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.]), ftrV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pu9 RCSB], [http://www.ebi.ac.uk/pdbsum/2pu9 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/2pu9_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Oxygen-evolving photosynthetic organisms regulate carbon metabolism through a light-dependent redox signalling pathway. Electrons are shuttled from photosystem I by means of ferredoxin (Fdx) to ferredoxin-thioredoxin reductase (FTR), which catalyses the two-electron-reduction of chloroplast thioredoxins (Trxs). These modify target enzyme activities by reduction, regulating carbon flow. FTR is unique in its use of a [4Fe-4S] cluster and a proximal disulphide bridge in the conversion of a light signal into a thiol signal. We determined the structures of FTR in both its one- and its two-electron-reduced intermediate states and of four complexes in the pathway, including the ternary Fdx-FTR-Trx complex. Here we show that, in the first complex (Fdx-FTR) of the pathway, the Fdx [2Fe-2S] cluster is positioned suitably for electron transfer to the FTR [4Fe-4S] centre. After the transfer of one electron, an intermediate is formed in which one sulphur atom of the FTR active site is free to attack a disulphide bridge in Trx and the other sulphur atom forms a fifth ligand for an iron atom in the FTR [4Fe-4S] centre--a unique structure in biology. Fdx then delivers a second electron that cleaves the FTR-Trx heterodisulphide bond, which occurs in the Fdx-FTR-Trx complex. In this structure, the redox centres of the three proteins are aligned to maximize the efficiency of electron transfer from the Fdx [2Fe-2S] cluster to the active-site disulphide of Trxs. These results provide a structural framework for understanding the mechanism of disulphide reduction by an iron-sulphur enzyme and describe previously unknown interaction networks for both Fdx and Trx (refs 4-6).

-	~~{{STRUCTURE_2pu9\| PDB=2pu9 \| SCENE= }}~~	+	Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.,Dai S, Friemann R, Glauser DA, Bourquin F, Manieri W, Schurmann P, Eklund H Nature. 2007 Jul 5;448(7149):92-6. PMID:17611542<ref>PMID:17611542</ref>

-	~~===Crystal srtucture~~ of the ~~binary complex between ferredoxin: thioredoxin reductase and thioredoxin f===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17611542}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2pu9]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en~~.~~wikipedia.org~~/~~wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA].~~	+

	==See Also==		==See Also==
	*[[Ferredoxin thioredoxin reductase\|Ferredoxin thioredoxin reductase]]		*[[Ferredoxin thioredoxin reductase\|Ferredoxin thioredoxin reductase]]
	*[[Thioredoxin\|Thioredoxin]]		*[[Thioredoxin\|Thioredoxin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017611542<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Spinacia oleracea]]		[[Category: Spinacia oleracea]]
	[[Category: Synechocystis sp.]]		[[Category: Synechocystis sp.]]

OCA at 16:49, 20 October 2012

2012-10-20T16:49:34Z

←Older revision		Revision as of 16:49, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2pu9]] is a 3 chain structure ~~of [[Ferredoxin thioredoxin reductase]] and [[Thioredoxin]]~~ with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA].	+	[[2pu9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA].

	==See Also==		==See Also==

OCA at 22:57, 26 July 2012

2012-07-26T22:57:10Z

←Older revision		Revision as of 22:57, 26 July 2012
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	[[Image:2pu9.png\|left\|200px]]		[[Image:2pu9.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2pu9\| PDB=2pu9 \| SCENE= }}		{{STRUCTURE_2pu9\| PDB=2pu9 \| SCENE= }}

	===Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f===		===Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17611542}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17611542 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17611542}}		{{ABSTRACT_PUBMED_17611542}}

	==About this Structure==		==About this Structure==
-	[[2pu9]] is a 3 chain structure of [[Thioredoxin]] with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA].	+	[[2pu9]] is a 3 chain structure of [[Ferredoxin thioredoxin reductase]] and [[Thioredoxin]] with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea] and [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU9 OCA].

	==See Also==		==See Also==
-	*[[Thioredoxin]]	+	*[[Ferredoxin thioredoxin reductase\|Ferredoxin thioredoxin reductase]]
		+	*[[Thioredoxin\|Thioredoxin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17611542~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017611542</ref><references group="xtra"/>
	[[Category: Spinacia oleracea]]		[[Category: Spinacia oleracea]]
	[[Category: Synechocystis sp.]]		[[Category: Synechocystis sp.]]

OCA: Protected "2pu9" [edit=sysop:move=sysop]

2010-12-26T22:29:31Z

Protected "2pu9" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:29, 26 December 2010