2pva - Revision history

OCA at 00:22, 28 December 2023

2023-12-28T00:22:40Z

←Older revision		Revision as of 00:22, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~OCS~~:~~CYSTEINESULFONIC~~+~~ACID~~'>~~OCS~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>~~[[3pva\|3pva]]~~</~~div></td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [https://pdbe.org/2pva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [https://www.ebi.ac.uk/pdbsum/2pva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [https://pdbe.org/2pva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [https://www.ebi.ac.uk/pdbsum/2pva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 27:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
-	~~[[Category: Penicillin amidase]]~~	+	[[Category: Brannigan JA]]
-	[[Category: Brannigan~~, J A~~]]	+	[[Category: Dauter Z]]
-	[[Category: Dauter, Z]]	+	[[Category: Dodson EJ]]
-	[[Category: Dodson~~, E J~~]]	+	[[Category: Dodson GG]]
-	[[Category: Dodson~~, G G~~]]	+	[[Category: McVey CE]]
-	[[Category: McVey~~, C E~~]]	+	[[Category: Pundle AV]]
-	[[Category: Pundle~~, A V~~]]	+	[[Category: Rao KN]]
-	[[Category: Rao~~, K N~~]]	+	[[Category: SivaRaman H]]
-	[[Category: SivaRaman, H]]	+	[[Category: Suresh CG]]
-	[[Category: Suresh~~, C G~~]]	+	[[Category: Verma CS]]
-	[[Category: Verma~~, C S]]~~	+
-	~~[[Category: Amidohydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ntn hydrolase]]~~	+
-	~~[[Category: Penicillin v acylase~~]]	+

OCA at 08:17, 19 January 2022

2022-01-19T08:17:48Z

OCA at 07:58, 15 April 2020

2020-04-15T07:58:50Z

←Older revision		Revision as of 07:58, 15 April 2020
Line 1:		Line 1:

	==OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS==		==OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS==
-	<StructureSection load='2pva' size='340' side='right' caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2pva' size='340' side='right'caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PVA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://pdbe.org/2pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://pdbe.org/2pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]

OCA at 05:59, 11 July 2018

2018-07-11T05:59:42Z

←Older revision		Revision as of 05:59, 11 July 2018
Line 1:		Line 1:
		+
	==OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS==		==OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS==
	<StructureSection load='2pva' size='340' side='right' caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2pva' size='340' side='right' caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://pdbe.org/2pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://pdbe.org/2pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pva_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pva_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pva ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 11:03, 11 September 2015

2015-09-11T11:03:56Z

←Older revision		Revision as of 11:03, 11 September 2015
Line 7:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://pdbe.org/2pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~PAC_BACSH PAC_BACSH~~]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[[http://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 15:35, 25 December 2014

2014-12-25T15:35:09Z

←Older revision		Revision as of 15:35, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PAC_BACSH PAC_BACSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 28:
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
-	[[Category: Brannigan, J A.]]	+	[[Category: Brannigan, J A]]
-	[[Category: Dauter, Z.]]	+	[[Category: Dauter, Z]]
-	[[Category: Dodson, E J.]]	+	[[Category: Dodson, E J]]
-	[[Category: Dodson, G G.]]	+	[[Category: Dodson, G G]]
-	[[Category: McVey, C E.]]	+	[[Category: McVey, C E]]
-	[[Category: Pundle, A V.]]	+	[[Category: Pundle, A V]]
-	[[Category: Rao, K N.]]	+	[[Category: Rao, K N]]
-	[[Category: SivaRaman, H.]]	+	[[Category: SivaRaman, H]]
-	[[Category: Suresh, C G.]]	+	[[Category: Suresh, C G]]
-	[[Category: Verma, C S.]]	+	[[Category: Verma, C S]]
	[[Category: Amidohydrolase]]		[[Category: Amidohydrolase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ntn hydrolase]]		[[Category: Ntn hydrolase]]
	[[Category: Penicillin v acylase]]		[[Category: Penicillin v acylase]]

OCA at 18:30, 30 September 2014

2014-09-30T18:30:23Z

←Older revision		Revision as of 18:30, 30 September 2014
Line 1:		Line 1:
-	~~[[Image:2pva.png\|left\|200px]]~~	+	==OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS==
-		+	<StructureSection load='2pva' size='340' side='right' caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{STRUCTURE_2pva\| PDB=2pva \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVA FirstGlance]. <br>
-	===OXIDIZED PENICILLIN V ACYLASE FROM B. SPHAERICUS===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [http://www.ebi.ac.uk/pdbsum/2pva PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pva_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Penicillin acylase\|Penicillin acylase]]		*[[Penicillin acylase\|Penicillin acylase]]
-		+	__TOC__
-	~~==Reference==~~	+	</StructureSection>
-	~~<ref group="xtra">PMID:010331865</ref><ref group="xtra">PMID:016511127</ref>~~<~~references group="xtra"~~/>	+
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]

OCA: Protected "2pva" [edit=sysop:move=sysop]

2013-01-07T18:24:48Z

Protected "2pva" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:24, 7 January 2013

OCA at 18:24, 7 January 2013

2013-01-07T18:24:46Z

←Older revision		Revision as of 18:24, 7 January 2013
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-	{{Seed}}
	[[Image:2pva.png\|left\|200px]]		[[Image:2pva.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2pva", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2pva\| PDB=2pva \| SCENE= }}		{{STRUCTURE_2pva\| PDB=2pva \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2PVA~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA].	+	[[2pva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA].
		+
		+	==See Also==
		+	*[[Penicillin acylase\|Penicillin acylase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~10331865~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:010331865</ref><ref group="xtra">PMID:016511127</ref><references group="xtra"/>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
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	[[Category: Verma, C S.]]		[[Category: Verma, C S.]]
	[[Category: Amidohydrolase]]		[[Category: Amidohydrolase]]
		+	[[Category: Hydrolase]]
	[[Category: Ntn hydrolase]]		[[Category: Ntn hydrolase]]
	[[Category: Penicillin v acylase]]		[[Category: Penicillin v acylase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:32:51 2009''

OCA at 18:32, 17 February 2009

2009-02-17T18:32:52Z

←Older revision		Revision as of 18:32, 17 February 2009
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	==About this Structure==		==About this Structure==
-	2PVA is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA].	+	2PVA is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA].

	==Reference==		==Reference==
-	Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members., Suresh CG, Pundle AV, SivaRaman H, Rao KN, Brannigan JA, McVey CE, Verma CS, Dauter Z, Dodson EJ, Dodson GG, Nat Struct Biol. 1999 May;6(5):414-6. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/10331865 10331865]~~	+	<ref group="xtra">PMID:10331865</ref><references group="xtra"/>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
-	[[Category: Single protein]]
	[[Category: Brannigan, J A.]]		[[Category: Brannigan, J A.]]
	[[Category: Dauter, Z.]]		[[Category: Dauter, Z.]]
Line 35:		Line 34:
	[[Category: Penicillin v acylase]]		[[Category: Penicillin v acylase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 04~~:26:~~19 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:32:51 2009''

←Older revision		Revision as of 08:17, 19 January 2022
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	<StructureSection load='2pva' size='340' side='right'caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2pva' size='340' side='right'caption='[[2pva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2PVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pva\|3pva]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3pva\|3pva]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [~~http~~://pdbe.org/2pva PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pva PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pva OCA], [https://pdbe.org/2pva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pva RCSB], [https://www.ebi.ac.uk/pdbsum/2pva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]