2qh1 - Revision history

OCA at 11:31, 30 August 2023

2023-08-30T11:31:57Z

←Older revision		Revision as of 11:31, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2qh1' size='340' side='right'caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2qh1' size='340' side='right'caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Theac Theac~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum_DSM_1728 Thermoplasma acidophilum DSM 1728]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[1pvm\|1pvm]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">Ta0289 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [https://pdbe.org/2qh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [https://www.ebi.ac.uk/pdbsum/2qh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [https://pdbe.org/2qh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [https://www.ebi.ac.uk/pdbsum/2qh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh1 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9HLD9_THEAC Q9HLD9_THEAC]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Theac~~]]	+	[[Category: Thermoplasma acidophilum DSM 1728]]
-	[[Category: Brown, G]]	+	[[Category: Brown G]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Proudfoot M]]
-	[[Category: Proudfoot, M]]	+	[[Category: Savchenko A]]
-	[[Category: Savchenko, A]]	+	[[Category: Singer AU]]
-	[[Category: Singer~~, A U~~]]	+	[[Category: Xu L]]
-	[[Category: Xu, L]]	+	[[Category: Yakunin AF]]
-	[[Category: Yakunin~~, A F]]~~	+
-	~~[[Category: Cbs-rubredoxin-like protein]]~~	+
-	~~[[Category: Fe+2]]~~	+
-	~~[[Category: Hypothetical protein]]~~	+
-	~~[[Category: Mcsg]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 08:19, 25 June 2021

2021-06-25T08:19:55Z

←Older revision		Revision as of 08:19, 25 June 2021
Line 1:		Line 1:

	==Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state==		==Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state==
-	<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2qh1' size='340' side='right'caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Theac Theac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Theac Theac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pvm\|1pvm]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [~~http~~://pdbe.org/2qh1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2qh1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [https://pdbe.org/2qh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [https://www.ebi.ac.uk/pdbsum/2qh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Theac]]		[[Category: Theac]]
	[[Category: Brown, G]]		[[Category: Brown, G]]

OCA at 11:01, 5 September 2018

2018-09-05T11:01:44Z

←Older revision		Revision as of 11:01, 5 September 2018
Line 1:		Line 1:
		+
	==Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state==		==Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state==
	<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://pdbe.org/2qh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://pdbe.org/2qh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qh1_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qh1_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qh1 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:39, 11 September 2015

2015-09-11T07:39:50Z

←Older revision		Revision as of 07:39, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermoplasma_acidophilum Thermoplasma acidophilum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theac Theac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~2303 Thermoplasma acidophilum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://pdbe.org/2qh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2qh1" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermoplasma acidophilum~~]]	+	[[Category: Theac]]
	[[Category: Brown, G]]		[[Category: Brown, G]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 13:21, 25 December 2014

2014-12-25T13:21:45Z

←Older revision		Revision as of 13:21, 25 December 2014
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Thermoplasma acidophilum]]		[[Category: Thermoplasma acidophilum]]
-	[[Category: Brown, G.]]	+	[[Category: Brown, G]]
-	[[Category: ~~MCSG, Midwest Center for~~ Structural ~~Genomics.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Proudfoot, M.]]	+	[[Category: Proudfoot, M]]
-	[[Category: Savchenko, A.]]	+	[[Category: Savchenko, A]]
-	[[Category: Singer, A U.]]	+	[[Category: Singer, A U]]
-	[[Category: Xu, L.]]	+	[[Category: Xu, L]]
-	[[Category: Yakunin, A F.]]	+	[[Category: Yakunin, A F]]
	[[Category: Cbs-rubredoxin-like protein]]		[[Category: Cbs-rubredoxin-like protein]]
	[[Category: Fe+2]]		[[Category: Fe+2]]
	[[Category: Hypothetical protein]]		[[Category: Hypothetical protein]]
	[[Category: Mcsg]]		[[Category: Mcsg]]
-	[[Category: ~~Midwest center for structural genomic]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
-	~~[[Category: Psi-2~~]]	+
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomic]]
-	[[Category: Structural genomics consortium]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 05:59, 10 October 2014

2014-10-10T05:59:27Z

←Older revision		Revision as of 05:59, 10 October 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 Thermoplasma acidophilum])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 Thermoplasma acidophilum])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:55, 9 June 2014

2014-06-09T06:55:03Z

←Older revision		Revision as of 06:55, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~2qh1.~~png~~\|~~left~~\|200px]]	+	==Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state==
		+	<StructureSection load='2qh1' size='340' side='right' caption='[[2qh1]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QH1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pvm\|1pvm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ta0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 Thermoplasma acidophilum])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qh1 RCSB], [http://www.ebi.ac.uk/pdbsum/2qh1 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qh1_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have identified a novel family of proteins, in which the N-terminal cystathionine beta-synthase (CBS) domain is fused to the C-terminal Zn ribbon domain. Four proteins were overexpressed in Escherichia coli and purified: TA0289 from Thermoplasma acidophilum, TV1335 from Thermoplasma volcanium, PF1953 from Pyrococcus furiosus, and PH0267 from Pyrococcus horikoshii. The purified proteins had a red/purple color in solution and an absorption spectrum typical of rubredoxins (Rds). Metal analysis of purified proteins revealed the presence of several metals, with iron and zinc being the most abundant metals (2-67% of iron and 12-74% of zinc). Crystal structures of both mercury- and iron-bound TA0289 (1.5-2.0 A resolution) revealed a dimeric protein whose intersubunit contacts are formed exclusively by the alpha-helices of two cystathionine beta-synthase subdomains, whereas the C-terminal domain has a classical Zn ribbon planar architecture. All proteins were reversibly reduced by chemical reductants (ascorbate or dithionite) or by the general Rd reductase NorW from E. coli in the presence of NADH. Reduced TA0289 was found to be capable of transferring electrons to cytochrome C from horse heart. Likewise, the purified Zn ribbon protein KTI11 from Saccharomyces cerevisiae had a purple color in solution and an Rd-like absorption spectrum, contained both iron and zinc, and was reduced by the Rd reductase NorW from E. coli. Thus, recombinant Zn ribbon domains from archaea and yeast demonstrate an Rd-like electron carrier activity in vitro. We suggest that, in vivo, some Zn ribbon domains might also bind iron and therefore possess an electron carrier activity, adding another physiological role to this large family of important proteins.

-	~~{{STRUCTURE_2qh1\| PDB=2qh1 \| SCENE= }}~~	+	Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain.,Proudfoot M, Sanders SA, Singer A, Zhang R, Brown G, Binkowski A, Xu L, Lukin JA, Murzin AG, Joachimiak A, Arrowsmith CH, Edwards AM, Savchenko AV, Yakunin AF J Mol Biol. 2008 Jan 4;375(1):301-15. Epub 2007 Nov 1. PMID:18021800<ref>PMID:18021800</ref>

-	~~===Structure of TA289~~, a ~~CBS-rubredoxin-like protein, in its Fe+2-bound state===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18021800}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2qh1]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018021800<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Thermoplasma acidophilum]]		[[Category: Thermoplasma acidophilum]]
	[[Category: Brown, G.]]		[[Category: Brown, G.]]

OCA at 11:34, 20 August 2012

2012-08-20T11:34:59Z

←Older revision		Revision as of 11:34, 20 August 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2qh1]] is a 2 chain structure ~~of [[TA0289]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA].	+	[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA].
-		+
-	~~==See Also==~~	+
-	*[[TA0289\|TA0289]]	+

	==Reference==		==Reference==

OCA at 00:04, 27 July 2012

2012-07-27T00:04:01Z

←Older revision		Revision as of 00:04, 27 July 2012
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	[[Image:2qh1.png\|left\|200px]]		[[Image:2qh1.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2qh1\| PDB=2qh1 \| SCENE= }}		{{STRUCTURE_2qh1\| PDB=2qh1 \| SCENE= }}

	===Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state===		===Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18021800}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_18021800}}		{{ABSTRACT_PUBMED_18021800}}

OCA at 07:12, 13 June 2012

2012-06-13T07:12:57Z

←Older revision		Revision as of 07:12, 13 June 2012
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	==About this Structure==		==About this Structure==
-	[[2qh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA].	+	[[2qh1]] is a 2 chain structure of [[TA0289]] with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH1 OCA].
		+
		+	==See Also==
		+	*[[TA0289\|TA0289]]

	==Reference==		==Reference==