2qva - Revision history

OCA at 09:02, 25 October 2023

2023-10-25T09:02:19Z

←Older revision		Revision as of 09:02, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2qva' size='340' side='right'caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='2qva' size='340' side='right'caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVA FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2qrx\|2qrx]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">translin ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=7227 DROME])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [https://pdbe.org/2qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [https://www.ebi.ac.uk/pdbsum/2qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qva ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [https://pdbe.org/2qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [https://www.ebi.ac.uk/pdbsum/2qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qva ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7JVK6_DROME Q7JVK6_DROME]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drome~~]]	+	[[Category: Drosophila melanogaster]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gupta~~, G D~~]]	+	[[Category: Gupta GD]]
-	[[Category: Kumar, V]]	+	[[Category: Kumar V]]
-	[[Category: Makde~~, R D]]~~	+	[[Category: Makde RD]]
-	~~[[Category: D. melanogaster]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Translin~~]]	+

OCA at 04:07, 2 July 2021

2021-07-02T04:07:10Z

←Older revision		Revision as of 04:07, 2 July 2021
Line 1:		Line 1:

	==Crystal structure of Drosophila melanogaster Translin protein==		==Crystal structure of Drosophila melanogaster Translin protein==
-	<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='2qva' size='340' side='right'caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2QVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVA FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qrx\|2qrx]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [~~http~~://pdbe.org/2qva PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2qva PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2qva ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [https://pdbe.org/2qva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [https://www.ebi.ac.uk/pdbsum/2qva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qva ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Drome]]		[[Category: Drome]]
		+	[[Category: Large Structures]]
	[[Category: Gupta, G D]]		[[Category: Gupta, G D]]
	[[Category: Kumar, V]]		[[Category: Kumar, V]]

OCA at 10:44, 5 September 2018

2018-09-05T10:44:11Z

←Older revision		Revision as of 10:44, 5 September 2018
Line 1:		Line 1:
		+
	==Crystal structure of Drosophila melanogaster Translin protein==		==Crystal structure of Drosophila melanogaster Translin protein==
	<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://pdbe.org/2qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://pdbe.org/2qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qva ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qva_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qva_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:08, 9 February 2016

2016-02-09T16:08:19Z

←Older revision		Revision as of 16:08, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qva ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:52, 10 September 2015

2015-09-10T23:52:19Z

←Older revision		Revision as of 23:52, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVA FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 ~~Drosophila melanogaster~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://pdbe.org/2qva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2qva" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drosophila melanogaster~~]]	+	[[Category: Drome]]
	[[Category: Gupta, G D]]		[[Category: Gupta, G D]]
	[[Category: Kumar, V]]		[[Category: Kumar, V]]

OCA at 16:07, 19 January 2015

2015-01-19T16:07:54Z

←Older revision		Revision as of 16:07, 19 January 2015
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Gupta, G D.]]	+	[[Category: Gupta, G D]]
-	[[Category: Kumar, V.]]	+	[[Category: Kumar, V]]
-	[[Category: Makde, R D.]]	+	[[Category: Makde, R D]]
	[[Category: D. melanogaster]]		[[Category: D. melanogaster]]
	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]
	[[Category: Translin]]		[[Category: Translin]]

OCA at 05:44, 10 October 2014

2014-10-10T05:44:34Z

←Older revision		Revision as of 05:44, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. <br>	+	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 23:
	Crystal structures of Drosophila mutant translin and characterization of translin variants reveal the structural plasticity of translin proteins.,Gupta GD, Makde RD, Rao BJ, Kumar V FEBS J. 2008 Aug;275(16):4235-49. Epub 2008 Jul 18. PMID:18647346<ref>PMID:18647346</ref>		Crystal structures of Drosophila mutant translin and characterization of translin variants reveal the structural plasticity of translin proteins.,Gupta GD, Makde RD, Rao BJ, Kumar V FEBS J. 2008 Aug;275(16):4235-49. Epub 2008 Jul 18. PMID:18647346<ref>PMID:18647346</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA: Protected "2qva" [edit=sysop:move=sysop]

2014-05-07T08:30:24Z

Protected "2qva" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:30, 7 May 2014

OCA at 08:30, 7 May 2014

2014-05-07T08:30:19Z

←Older revision		Revision as of 08:30, 7 May 2014
Line 1:		Line 1:
-	~~{{Seed}}~~	+	==Crystal structure of Drosophila melanogaster Translin protein==
-	[[~~Image:~~2qva.~~png~~\|~~left~~\|200px]]	+	<StructureSection load='2qva' size='340' side='right' caption='[[2qva]], [[Resolution\|resolution]] 3.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2qva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qrx\|2qrx]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">translin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qva RCSB], [http://www.ebi.ac.uk/pdbsum/2qva PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qva_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Translin protein is highly conserved in eukaryotes. Human translin binds both ssDNA and RNA. Its nucleic acid binding site results from a combination of basic regions in the octameric structure. We report here the first biochemical characterization of wild-type Drosophila melanogaster (drosophila) translin and a chimeric translin, and present 3.5 A resolution crystal structures of drosophila P168S mutant translin from two crystal forms. The wild-type drosophila translin most likely exists as an octamer/decamer, and binds to the ssDNA Bcl-CL1 sequence. In contrast, ssDNA binding-incompetent drosophila P168S mutant translin exists as a tetramer. The structures of the mutant translin are identical in both crystal forms, and their C-terminal residues are disordered. The chimeric protein, possessing two nucleic acid binding motifs of drosophila translin, the C-terminal residues of human translin, and serine at position 168, attains the octameric state and binds to ssDNA. The present studies suggest that the oligomeric status of translin critically influences the DNA binding properties of translin proteins.

-	~~<!--~~	+	Crystal structures of Drosophila mutant translin and characterization of translin variants reveal the structural plasticity of translin proteins.,Gupta GD, Makde RD, Rao BJ, Kumar V FEBS J. 2008 Aug;275(16):4235-49. Epub 2008 Jul 18. PMID:18647346<ref>PMID:18647346</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2qva"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2qva\| PDB=2qva \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~Drosophila melanogaster Translin protein===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_18647346}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 18647346 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_18647346}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~2QVA is a 4 chains structure of sequences from [http:~~/~~/en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:18647346<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Gupta, G D.]]		[[Category: Gupta, G D.]]
	[[Category: Kumar, V.]]		[[Category: Kumar, V.]]
	[[Category: Makde, R D.]]		[[Category: Makde, R D.]]
-	[[Category: Crystal structure]]
	[[Category: D. melanogaster]]		[[Category: D. melanogaster]]
	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]
	[[Category: Translin]]		[[Category: Translin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:03:51 2009''

OCA at 09:03, 17 February 2009

2009-02-17T09:03:51Z

←Older revision		Revision as of 09:03, 17 February 2009
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-	[[Image:2qva.~~jpg~~\|left\|200px]]	+	[[Image:2qva.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	2QVA is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA].	+	2QVA is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVA OCA].

	==Reference==		==Reference==
-	Crystal structures of Drosophila mutant translin and characterization of translin variants reveal the structural plasticity of translin proteins., Gupta GD, Makde RD, Rao BJ, Kumar V, FEBS J. 2008 Jul 16. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18647346 18647346]~~	+	<ref group="xtra">PMID:18647346</ref><references group="xtra"/>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Single protein]]
	[[Category: Gupta, G D.]]		[[Category: Gupta, G D.]]
	[[Category: Kumar, V.]]		[[Category: Kumar, V.]]
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	[[Category: Translin]]		[[Category: Translin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 6 12~~:46:~~50 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:03:51 2009''