2r8t - Revision history

OCA at 11:49, 30 August 2023

2023-08-30T11:49:13Z

←Older revision		Revision as of 11:49, 30 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8T FirstGlance]. <br>		<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8T FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FBP:BETA~~-~~FRUCTOSE-1~~,~~6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>glpX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562 Escherichia coli])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [https://pdbe.org/2r8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [https://www.ebi.ac.uk/pdbsum/2r8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [https://pdbe.org/2r8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [https://www.ebi.ac.uk/pdbsum/2r8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8t ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GLPX_ECOLI GLPX_ECOLI]] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is likely to be involved in gluconeogenesis during growth on glycerol. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5-bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate.<ref>PMID:10986273</ref> <ref>PMID:19073594</ref>	+	[https://www.uniprot.org/uniprot/GLPX_ECOLI GLPX_ECOLI] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is likely to be involved in gluconeogenesis during growth on glycerol. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5-bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate.<ref>PMID:10986273</ref> <ref>PMID:19073594</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Fructose-bisphosphatase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brown, G]]	+	[[Category: Brown G]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Edwards AM]]
-	[[Category: Lunin~~, V V~~]]	+	[[Category: Lunin VV]]
-	[[Category: Savchenko, A]]	+	[[Category: Savchenko A]]
-	[[Category: Skarina, T]]	+	[[Category: Skarina T]]
-	[[Category: Yakunin, A]]	+	[[Category: Yakunin A]]
-	~~[[Category: 6-bisphosphatase]]~~	+
-	~~[[Category: Carbohydrate metabolism]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Glpx]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 04:18, 2 July 2021

2021-07-02T04:18:15Z

←Older revision		Revision as of 04:18, 2 July 2021
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	==Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate==		==Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate==
-	<StructureSection load='2r8t' size='340' side='right' caption='[[2r8t]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='2r8t' size='340' side='right'caption='[[2r8t]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2R8T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8T FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [~~http~~://pdbe.org/2r8t PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2r8t PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8t ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [https://pdbe.org/2r8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [https://www.ebi.ac.uk/pdbsum/2r8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8t ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GLPX_ECOLI GLPX_ECOLI]] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is likely to be involved in gluconeogenesis during growth on glycerol. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5-bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate.<ref>PMID:10986273</ref> <ref>PMID:19073594</ref>	+	[[https://www.uniprot.org/uniprot/GLPX_ECOLI GLPX_ECOLI]] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is likely to be involved in gluconeogenesis during growth on glycerol. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5-bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate.<ref>PMID:10986273</ref> <ref>PMID:19073594</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]	+	*[[Fructose-1%2C6-bisphosphatase 3D structures\|Fructose-1%2C6-bisphosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 30:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
		+	[[Category: Large Structures]]
	[[Category: Brown, G]]		[[Category: Brown, G]]
	[[Category: Edwards, A M]]		[[Category: Edwards, A M]]

OCA at 11:10, 5 September 2018

2018-09-05T11:10:49Z

←Older revision		Revision as of 11:10, 5 September 2018
Line 1:		Line 1:
		+
	==Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate==		==Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate==
	<StructureSection load='2r8t' size='340' side='right' caption='[[2r8t]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2r8t' size='340' side='right' caption='[[2r8t]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://pdbe.org/2r8t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://pdbe.org/2r8t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8t ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8t_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8t_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r8t ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 37:		Line 38:
	[[Category: 6-bisphosphatase]]		[[Category: 6-bisphosphatase]]
	[[Category: Carbohydrate metabolism]]		[[Category: Carbohydrate metabolism]]
		+	[[Category: Cytoplasm]]
	[[Category: Glpx]]		[[Category: Glpx]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 17:41, 11 September 2015

2015-09-11T17:41:59Z

←Older revision		Revision as of 17:41, 11 September 2015
Line 6:		Line 6:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://pdbe.org/2r8t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 19:44, 25 December 2014

2014-12-25T19:44:24Z

←Older revision		Revision as of 19:44, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R8T FirstGlance]. <br>		<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R8T FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GLPX_ECOLI GLPX_ECOLI]] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is likely to be involved in gluconeogenesis during growth on glycerol. Also displays a low activity toward glucose 1,6-bisphosphate, and no activity against ribulose 1,5-bisphosphate, fructose 2,6-bisphosphate, or fructose 1-phosphate.<ref>PMID:10986273</ref> <ref>PMID:19073594</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 23:
	==See Also==		==See Also==
	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]		*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
-	[[Category: Brown, G.]]	+	[[Category: Brown, G]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: Lunin, V V.]]	+	[[Category: Lunin, V V]]
-	[[Category: Savchenko, A.]]	+	[[Category: Savchenko, A]]
-	[[Category: Skarina, T.]]	+	[[Category: Skarina, T]]
-	[[Category: Yakunin, A.]]	+	[[Category: Yakunin, A]]
	[[Category: 6-bisphosphatase]]		[[Category: 6-bisphosphatase]]
	[[Category: Carbohydrate metabolism]]		[[Category: Carbohydrate metabolism]]
	[[Category: Glpx]]		[[Category: Glpx]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:49, 29 September 2014

2014-09-29T07:49:23Z

←Older revision		Revision as of 07:49, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2r8t.png\|left\|200px]]~~	+	==Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate==
-		+	<StructureSection load='2r8t' size='340' side='right' caption='[[2r8t]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~{{STRUCTURE_2r8t\| PDB=2r8t \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2r8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R8T FirstGlance]. <br>
-	===Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r8t RCSB], [http://www.ebi.ac.uk/pdbsum/2r8t PDBsum]</span></td></tr>
-	[[2r8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].	+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8t_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]		*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]

OCA at 20:41, 20 October 2012

2012-10-20T20:41:56Z

←Older revision		Revision as of 20:41, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[2r8t]] is a 1 chain structure ~~of [[Fructose-1%2C6-bisphosphatase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].	+	[[2r8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].

	==See Also==		==See Also==

OCA: Protected "2r8t" [edit=sysop:move=sysop]

2012-07-27T11:19:45Z

Protected "2r8t" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:19, 27 July 2012

OCA at 11:19, 27 July 2012

2012-07-27T11:19:43Z

←Older revision		Revision as of 11:19, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2r8t.png\|left\|200px]]		[[Image:2r8t.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2r8t", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2r8t\| PDB=2r8t \| SCENE= }}		{{STRUCTURE_2r8t\| PDB=2r8t \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~2R8T~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].	+	[[2r8t]] is a 1 chain structure of [[Fructose-1%2C6-bisphosphatase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].
		+
		+	==See Also==
		+	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
Line 25:		Line 21:
	[[Category: 6-bisphosphatase]]		[[Category: 6-bisphosphatase]]
	[[Category: Carbohydrate metabolism]]		[[Category: Carbohydrate metabolism]]
-	[[Category: Cytoplasm]]
	[[Category: Glpx]]		[[Category: Glpx]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:57:06 2009''

OCA at 02:57, 18 February 2009

2009-02-18T02:57:07Z

←Older revision		Revision as of 02:57, 18 February 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2r8t.png\|left\|200px]]

-	The ~~entry 2r8t~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2r8t", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2r8t\| PDB=2r8t \| SCENE= }}

-	~~Authors: Lunin~~, ~~V.V~~., ~~Skarina, T., Brown, G., Yakunin, A., Edwards, A.M., Savchenko, A.~~	+	===Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate===

-	Description: Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate

		+	==About this Structure==
		+	2R8T is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8T OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Fructose-bisphosphatase]]
		+	[[Category: Brown, G.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: Lunin, V V.]]
		+	[[Category: Savchenko, A.]]
		+	[[Category: Skarina, T.]]
		+	[[Category: Yakunin, A.]]
		+	[[Category: 6-bisphosphatase]]
		+	[[Category: Carbohydrate metabolism]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Glpx]]
		+	[[Category: Hydrolase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 11 08~~:48:~~03 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:57:06 2009''