2rg0 - Revision history

OCA at 20:54, 20 October 2021

2021-10-20T20:54:20Z

←Older revision		Revision as of 20:54, 20 October 2021
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	<StructureSection load='2rg0' size='340' side='right'caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2rg0' size='340' side='right'caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=CBI:CELLOBIOSE'~~>~~CBI</scene>,~~ <scene name='pdbligand=~~CTT~~:BETA-D-~~GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE~~'>~~CTT~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [~~http~~://pdbe.org/2rg0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2rg0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2rg0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [https://pdbe.org/2rg0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [https://www.ebi.ac.uk/pdbsum/2rg0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rg0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:44, 25 December 2019

2019-12-25T09:44:13Z

←Older revision		Revision as of 09:44, 25 December 2019
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	==Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose==		==Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose==
-	<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='2rg0' size='340' side='right'caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 16460]]		[[Category: Atcc 16460]]
		+	[[Category: Large Structures]]
	[[Category: Koivula, A]]		[[Category: Koivula, A]]
	[[Category: Parkkinen, T]]		[[Category: Parkkinen, T]]

OCA at 16:27, 15 August 2018

2018-08-15T16:27:10Z

←Older revision		Revision as of 16:27, 15 August 2018
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	<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Melanocarpus_albomyces Melanocarpus albomyces~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBI:CELLOBIOSE'>CBI</scene>, <scene name='pdbligand=CTT:BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE'>CTT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBI:CELLOBIOSE'>CBI</scene>, <scene name='pdbligand=CTT:BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE'>CTT</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Melanocarpus albomyces~~]]	+	[[Category: Atcc 16460]]
	[[Category: Koivula, A]]		[[Category: Koivula, A]]
	[[Category: Parkkinen, T]]		[[Category: Parkkinen, T]]

OCA at 18:57, 1 August 2018

2018-08-01T18:57:56Z

←Older revision		Revision as of 18:57, 1 August 2018
Line 1:		Line 1:
		+
	==Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose==		==Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose==
	<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://pdbe.org/2rg0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://pdbe.org/2rg0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rg0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rg0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rg0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:13, 7 February 2016

2016-02-07T11:13:09Z

←Older revision		Revision as of 11:13, 7 February 2016
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-~~cellobiosidase~~ Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://pdbe.org/2rg0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rg0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2rg0" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cellulose 1,4-beta-cellobiosidase]]
	[[Category: Melanocarpus albomyces]]		[[Category: Melanocarpus albomyces]]
	[[Category: Koivula, A]]		[[Category: Koivula, A]]

OCA at 13:48, 19 January 2015

2015-01-19T13:48:43Z

←Older revision		Revision as of 13:48, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBI:CELLOBIOSE'>CBI</scene>, <scene name='pdbligand=CTT:BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE'>CTT</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBI:CELLOBIOSE'>CBI</scene>, <scene name='pdbligand=CTT:BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE'>CTT</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Cellulose 1,4-beta-cellobiosidase]]		[[Category: Cellulose 1,4-beta-cellobiosidase]]
	[[Category: Melanocarpus albomyces]]		[[Category: Melanocarpus albomyces]]
-	[[Category: Koivula, A.]]	+	[[Category: Koivula, A]]
-	[[Category: Parkkinen, T.]]	+	[[Category: Parkkinen, T]]
-	[[Category: Rouvinen, J.]]	+	[[Category: Rouvinen, J]]
-	[[Category: Vehmaanper, J.]]	+	[[Category: Vehmaanper, J]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 18:16, 30 September 2014

2014-09-30T18:16:34Z

←Older revision		Revision as of 18:16, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2rg0.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose==
		+	<StructureSection load='2rg0' size='340' side='right' caption='[[2rg0]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RG0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBI:CELLOBIOSE'>CBI</scene>, <scene name='pdbligand=CTT:BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSYL-(1- 4)-BETA-D-GLUCOPYRANOSE'>CTT</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfw\|2rfw]], [[2rfy\|2rfy]], [[2rfz\|2rfz]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rg0 RCSB], [http://www.ebi.ac.uk/pdbsum/2rg0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rg0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cellobiohydrolase from Melanocarpus albomyces (Cel7B) is a thermostable, single-module, cellulose-degrading enzyme. It has relatively low catalytic activity under normal temperatures, which allows structural studies of the binding of unmodified substrates to the native enzyme. In this study, we have determined the crystal structure of native Ma Cel7B free and in complex with three different cello-oligomers: cellobiose (Glc(2)), cellotriose (Glc(3)), and cellotetraose (Glc(4)), at high resolution (1.6-2.1 A). In each case, four molecules were found in the asymmetric unit, which provided 12 different complex structures. The overall fold of the enzyme is characteristic of a glycoside hydrolase family 7 cellobiohydrolase, where the loops extending from the core beta-sandwich structure form a long tunnel composed of multiple subsites for the binding of the glycosyl units of a cellulose chain. The catalytic residues at the reducing end of the tunnel are conserved, and the mechanism is expected to be retaining similarly to the other family 7 members. The oligosaccharides in different complex structures occupied different subsite sets, which partly overlapped and ranged from -5 to +2. In four cellotriose and one cellotetraose complex structures, the cello-oligosaccharide also spanned over the cleavage site (-1/+1). There were surprisingly large variations in the amino acid side chain conformations and in the positions of glycosyl units in the different cello-oligomer complexes, particularly at subsites near the catalytic site. However, in each complex structure, all glycosyl residues were in the chair (4C(1)) conformation. Implications in relation to the complex structures with respect to the reaction mechanism are discussed.

-	~~{{STRUCTURE_2rg0\| PDB=2rg0 \| SCENE= }}~~	+	Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding.,Parkkinen T, Koivula A, Vehmaanpera J, Rouvinen J Protein Sci. 2008 Aug;17(8):1383-94. Epub 2008 May 21. PMID:18499583<ref>PMID:18499583</ref>

-	~~===Crystal structure~~ of ~~cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18499583}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2rg0]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018499583<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Cellulose 1,4-beta-cellobiosidase]]		[[Category: Cellulose 1,4-beta-cellobiosidase]]
	[[Category: Melanocarpus albomyces]]		[[Category: Melanocarpus albomyces]]

OCA: Protected "2rg0" [edit=sysop:move=sysop]

2013-01-07T20:54:38Z

Protected "2rg0" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:54, 7 January 2013

OCA at 20:54, 7 January 2013

2013-01-07T20:54:36Z

←Older revision		Revision as of 20:54, 7 January 2013
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-	{{Seed}}
	[[Image:2rg0.png\|left\|200px]]		[[Image:2rg0.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2rg0\| PDB=2rg0 \| SCENE= }}		{{STRUCTURE_2rg0\| PDB=2rg0 \| SCENE= }}

	===Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose===		===Crystal structure of cellobiohydrolase from Melanocarpus albomyces complexed with cellotetraose===

-
-	<!--
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	{{ABSTRACT_PUBMED_18499583}}		{{ABSTRACT_PUBMED_18499583}}

	==About this Structure==		==About this Structure==
-	~~2RG0~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA].	+	[[2rg0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18499583~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018499583</ref><references group="xtra"/>
	[[Category: Cellulose 1,4-beta-cellobiosidase]]		[[Category: Cellulose 1,4-beta-cellobiosidase]]
	[[Category: Melanocarpus albomyces]]		[[Category: Melanocarpus albomyces]]
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	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:25:20 2009''

OCA at 11:25, 16 February 2009

2009-02-16T11:25:21Z

←Older revision		Revision as of 11:25, 16 February 2009
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	{{Seed}}		{{Seed}}
-	[[Image:2rg0.~~jpg~~\|left\|200px]]	+	[[Image:2rg0.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	2RG0 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA].	+	2RG0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG0 OCA].

	==Reference==		==Reference==
-	Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding., Parkkinen T, Koivula A, Vehmaanpera J, Rouvinen J, Protein Sci. 2008 Aug;17(8):1383-94. Epub 2008 May 21. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18499583 18499583]~~	+	<ref group="xtra">PMID:18499583</ref><references group="xtra"/>
	[[Category: Cellulose 1,4-beta-cellobiosidase]]		[[Category: Cellulose 1,4-beta-cellobiosidase]]
	[[Category: Melanocarpus albomyces]]		[[Category: Melanocarpus albomyces]]
-	[[Category: Single protein]]
	[[Category: Koivula, A.]]		[[Category: Koivula, A.]]
	[[Category: Parkkinen, T.]]		[[Category: Parkkinen, T.]]
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	[[Category: Hydrolase]]		[[Category: Hydrolase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Sep 17~~ 13:35:~~05 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:25:20 2009''