2rqe - Revision history

OCA at 19:15, 29 May 2024

2024-05-29T19:15:51Z

←Older revision		Revision as of 19:15, 29 May 2024
Line 1:		Line 1:

	==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==		==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==
-	<StructureSection load='2rqe' size='340' side='right'caption='[[2rqe~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2rqe' size='340' side='right'caption='[[2rqe]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bommo Bommo~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [https://pdbe.org/2rqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [https://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [https://pdbe.org/2rqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [https://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BGBP_BOMMO BGBP_BOMMO]] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.<ref>PMID:10671539</ref> <ref>PMID:3136171</ref>	+	[https://www.uniprot.org/uniprot/BGBP_BOMMO BGBP_BOMMO] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.<ref>PMID:10671539</ref> <ref>PMID:3136171</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bommo~~]]	+	[[Category: Bombyx mori]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ashida, M]]	+	[[Category: Ashida M]]
-	[[Category: Horiuchi, M]]	+	[[Category: Horiuchi M]]
-	[[Category: Inagaki, F]]	+	[[Category: Inagaki F]]
-	[[Category: Kumeta, H]]	+	[[Category: Kumeta H]]
-	[[Category: Ochiai, M]]	+	[[Category: Ochiai M]]
-	[[Category: Ogura, K]]	+	[[Category: Ogura K]]
-	[[Category: Takahasi, K]]	+	[[Category: Takahasi K]]
-	~~[[Category: 3-glucan]]~~	+
-	~~[[Category: Beta-1]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Immune response]]~~	+
-	~~[[Category: Innate immunity]]~~	+
-	~~[[Category: Protein]]~~	+
-	~~[[Category: Secreted]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 06:56, 16 March 2022

2022-03-16T06:56:19Z

←Older revision		Revision as of 06:56, 16 March 2022
Line 3:		Line 3:
	<StructureSection load='2rqe' size='340' side='right'caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2rqe' size='340' side='right'caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2RQE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [~~http~~://pdbe.org/2rqe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [https://pdbe.org/2rqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [https://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BGBP_BOMMO BGBP_BOMMO]] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.<ref>PMID:10671539</ref> <ref>PMID:3136171</ref>	+	[[https://www.uniprot.org/uniprot/BGBP_BOMMO BGBP_BOMMO]] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.<ref>PMID:10671539</ref> <ref>PMID:3136171</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:04, 17 June 2020

2020-06-17T11:04:14Z

←Older revision		Revision as of 11:04, 17 June 2020
Line 1:		Line 1:

	==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==		==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==
-	<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2rqe' size='340' side='right'caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2RQE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://pdbe.org/2rqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://pdbe.org/2rqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Bommo]]		[[Category: Bommo]]
		+	[[Category: Large Structures]]
	[[Category: Ashida, M]]		[[Category: Ashida, M]]
	[[Category: Horiuchi, M]]		[[Category: Horiuchi, M]]

OCA at 08:19, 12 September 2018

2018-09-12T08:19:08Z

←Older revision		Revision as of 08:19, 12 September 2018
Line 1:		Line 1:
		+
	==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==		==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==
	<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://pdbe.org/2rqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://pdbe.org/2rqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rqe_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rqe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 10:54, 9 February 2016

2016-02-09T10:54:19Z

←Older revision		Revision as of 10:54, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bombyx_mori Bombyx mori~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://pdbe.org/2rqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rqe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2rqe" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bombyx mori~~]]	+	[[Category: Bommo]]
	[[Category: Ashida, M]]		[[Category: Ashida, M]]
	[[Category: Horiuchi, M]]		[[Category: Horiuchi, M]]

OCA at 06:24, 25 December 2014

2014-12-25T06:24:33Z

←Older revision		Revision as of 06:24, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BGBP_BOMMO BGBP_BOMMO]] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.<ref>PMID:10671539</ref> <ref>PMID:3136171</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Bombyx mori]]		[[Category: Bombyx mori]]
-	[[Category: Ashida, M.]]	+	[[Category: Ashida, M]]
-	[[Category: Horiuchi, M.]]	+	[[Category: Horiuchi, M]]
-	[[Category: Inagaki, F.]]	+	[[Category: Inagaki, F]]
-	[[Category: Kumeta, H.]]	+	[[Category: Kumeta, H]]
-	[[Category: Ochiai, M.]]	+	[[Category: Ochiai, M]]
-	[[Category: Ogura, K.]]	+	[[Category: Ogura, K]]
-	[[Category: Takahasi, K.]]	+	[[Category: Takahasi, K]]
	[[Category: 3-glucan]]		[[Category: 3-glucan]]
	[[Category: Beta-1]]		[[Category: Beta-1]]

OCA at 01:53, 1 October 2014

2014-10-01T01:53:41Z

←Older revision		Revision as of 01:53, 1 October 2014
Line 1:		Line 1:
-	[[~~Image~~:2rqe.~~png\|left~~\|200px]]	+	==Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition==
		+	<StructureSection load='2rqe' size='340' side='right' caption='[[2rqe]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RQE FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rqe RCSB], [http://www.ebi.ac.uk/pdbsum/2rqe PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rqe_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The beta-1,3-glucan recognition protein (betaGRP)/Gram-negative bacteria-binding protein 3 (GNBP3) is a crucial pattern-recognition receptor that specifically binds beta-1,3-glucan, a component of fungal cell walls. It evokes innate immunity against fungi through activation of the prophenoloxidase (proPO) cascade and Toll pathway in invertebrates. The betaGRP consists of an N-terminal beta-1,3-glucan-recognition domain and a C-terminal glucanase-like domain, with the former reported to be responsible for the proPO cascade activation. This report shows the solution structure of the N-terminal beta-1,3-glucan recognition domain of silkworm betaGRP. Although the N-terminal domain of betaGRP has a beta-sandwich fold, often seen in carbohydrate-binding modules, both NMR titration experiments and mutational analysis showed that betaGRP has a binding mechanism which is distinct from those observed in previously reported carbohydarate-binding domains. Our results suggest that betaGRP is a beta-1,3-glucan-recognition protein that specifically recognizes a triple-helical structure of beta-1,3-glucan.

-	~~{{STRUCTURE_2rqe\| PDB=2rqe \| SCENE= }}~~	+	Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition.,Takahasi K, Ochiai M, Horiuchi M, Kumeta H, Ogura K, Ashida M, Inagaki F Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11679-84. Epub 2009 Jun 26. PMID:19561300<ref>PMID:19561300</ref>

-	~~===Solution structure of the silkworm bGRP~~/~~GNBP3 N-terminal domain reveals the mechanism for b-1~~,~~3-glucan specific recognition===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19561300}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2rqe]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bombyx_mori Bombyx mori]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019561300<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bombyx mori]]		[[Category: Bombyx mori]]
	[[Category: Ashida, M.]]		[[Category: Ashida, M.]]

OCA: Protected "2rqe" [edit=sysop:move=sysop]

2013-01-07T22:48:39Z

Protected "2rqe" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:48, 7 January 2013

OCA at 22:48, 7 January 2013

2013-01-07T22:48:35Z

←Older revision		Revision as of 22:48, 7 January 2013
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-	{{Seed}}
	[[Image:2rqe.png\|left\|200px]]		[[Image:2rqe.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2rqe", creates the "Structure Box" on the page.
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2rqe\| PDB=2rqe \| SCENE= }}		{{STRUCTURE_2rqe\| PDB=2rqe \| SCENE= }}

	===Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition===		===Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19561300}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19561300 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19561300}}		{{ABSTRACT_PUBMED_19561300}}

	==About this Structure==		==About this Structure==
-	~~2RQE~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA].	+	[[2rqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19561300~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019561300</ref><references group="xtra"/>
	[[Category: Bombyx mori]]		[[Category: Bombyx mori]]
	[[Category: Ashida, M.]]		[[Category: Ashida, M.]]
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	[[Category: Secreted]]		[[Category: Secreted]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 09:43:33 2010''

OCA at 07:43, 18 January 2010

2010-01-18T07:43:34Z

←Older revision		Revision as of 07:43, 18 January 2010
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	===Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition===		===Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19561300}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19561300 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19561300}}

	==About this Structure==		==About this Structure==
	2RQE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA].		2RQE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19561300</ref><references group="xtra"/>
	[[Category: Bombyx mori]]		[[Category: Bombyx mori]]
	[[Category: Ashida, M.]]		[[Category: Ashida, M.]]
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	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Sep 30 20~~:17:~~45 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 09:43:33 2010''