2v49 - Revision history

OCA: Redirecting to 4v5a

2014-12-10T15:14:19Z

Redirecting to 4v5a

←Older revision		Revision as of 15:14, 10 December 2014
Line 1:		Line 1:
-	~~==STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.==~~	+	#REDIRECT [[4v5a]] This PDB entry is obsolete and replaced by 4v5a
-	~~<StructureSection load='2v49' size='340' side='right' caption='~~[[~~2v49]], [[Resolution\|resolution]] 3.50Å' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[2v49~~]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V49 FirstGlance]. <br>	+
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v46\|2v46]], [[2v47\|2v47]], [[2v48\|2v48]], [[1fjg\|1fjg]], [[1gix\|1gix]], [[1i94\|1i94]], [[1i95\|1i95]], [[1i96\|1i96]], [[1i97\|1i97]], [[1ibk\|1ibk]], [[1ibl\|1ibl]], [[1ibm\|1ibm]], [[1j5e\|1j5e]], [[1jgo\|1jgo]], [[1jgp\|1jgp]], [[1jgq\|1jgq]], [[1l1u\|1l1u]], [[1n32\|1n32]], [[1n33\|1n33]], [[1n34\|1n34]], [[1n36\|1n36]], [[1pns\|1pns]], [[1pnx\|1pnx]], [[1xmo\|1xmo]], [[1xmq\|1xmq]], [[1xnq\|1xnq]], [[1xnr\|1xnr]], [[1yl4\|1yl4]], [[2b64\|2b64]], [[2b9m\|2b9m]], [[2b9o\|2b9o]], [[2f4v\|2f4v]], [[2j00\|2j00]], [[2j02\|2j02]], [[2uu9\|2uu9]], [[2uua\|2uua]], [[2uub\|2uub]], [[2uuc\|2uuc]], [[2uxb\|2uxb]], [[2uxc\|2uxc]]</td></tr>	+
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v49 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v49 RCSB], [http://www.ebi.ac.uk/pdbsum/2v49 PDBsum]</span></td></tr>	+
-	~~<table>~~	+
-	~~== Evolutionary Conservation ==~~	+
-	~~[[Image:Consurf_key_small.gif\|200px\|right]]~~	+
-	~~Check<jmol>~~	+
-	~~<jmolCheckbox>~~	+
-	~~<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v49_consurf.spt"</scriptWhenChecked>~~	+
-	~~<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>~~	+
-	~~<text>to colour the structure by Evolutionary Conservation</text>~~	+
-	~~</jmolCheckbox>~~	+
-	~~</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method~~ and ~~the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].~~	+
-	~~<div style="clear:both"></div>~~	+
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	~~In bacteria, disassembly of the ribosome at the end of translation is facilitated~~ by an essential protein factor termed ribosome recycling factor (RRF), which works in concert with elongation factor G. Here we describe the crystal structure of the Thermus thermophilus RRF bound to a 70S ribosomal complex containing a stop codon in the A site, a transfer RNA anticodon stem-loop in the P site and tRNA(fMet) in the E site. The work demonstrates that structures of translation factors bound to 70S ribosomes can be determined at reasonably high resolution. Contrary to earlier reports, we did not observe any RRF-induced changes in bridges connecting the two subunits. This suggests that such changes are not a direct requirement for or consequence of RRF binding but possibly arise from the subsequent stabilization of a hybrid state of the ribosome.	+
-		+
-	Crystal structure of the ribosome recycling factor bound to the ribosome.,Weixlbaumer A, Petry S, Dunham CM, Selmer M, Kelley AC, Ramakrishnan V Nat Struct Mol Biol. 2007 Aug;14(8):733-7. Epub 2007 Jul 29. PMID:17660830<ref>PMID:17660830</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-		+
-	~~==See Also==~~	+
-	*[[Ribosome 3D structures\|Ribosome 3D structures]]	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Thermus thermophilus]]~~	+
-	~~[[Category: Dunham, C M.]]~~	+
-	~~[[Category: Kelley, A C.]]~~	+
-	~~[[Category: Petry, S.]]~~	+
-	~~[[Category: Ramakrishnan, V.]]~~	+
-	~~[[Category: Selmer, M.]]~~	+
-	~~[[Category: Weixlbaumer, A.]]~~	+
-	~~[[Category: Mrna]]~~	+
-	~~[[Category: Recycling]]~~	+
-	~~[[Category: Ribosome]]~~	+
-	~~[[Category: Rrf]]~~	+
-	~~[[Category: Translation]]~~	+
-	~~[[Category: Trna]]~~	+

OCA at 02:18, 1 October 2014

2014-10-01T02:18:23Z

←Older revision		Revision as of 02:18, 1 October 2014
Line 1:		Line 1:
-	~~{{Large structure}}~~	+	==STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.==
-	~~{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}~~	+	<StructureSection load='2v49' size='340' side='right' caption='[[2v49]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===	+	== Structural highlights ==
-	~~{{ABSTRACT_PUBMED_17660830}}~~	+	<table><tr><td colspan='2'>[[2v49]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V49 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v46\|2v46]], [[2v47\|2v47]], [[2v48\|2v48]], [[1fjg\|1fjg]], [[1gix\|1gix]], [[1i94\|1i94]], [[1i95\|1i95]], [[1i96\|1i96]], [[1i97\|1i97]], [[1ibk\|1ibk]], [[1ibl\|1ibl]], [[1ibm\|1ibm]], [[1j5e\|1j5e]], [[1jgo\|1jgo]], [[1jgp\|1jgp]], [[1jgq\|1jgq]], [[1l1u\|1l1u]], [[1n32\|1n32]], [[1n33\|1n33]], [[1n34\|1n34]], [[1n36\|1n36]], [[1pns\|1pns]], [[1pnx\|1pnx]], [[1xmo\|1xmo]], [[1xmq\|1xmq]], [[1xnq\|1xnq]], [[1xnr\|1xnr]], [[1yl4\|1yl4]], [[2b64\|2b64]], [[2b9m\|2b9m]], [[2b9o\|2b9o]], [[2f4v\|2f4v]], [[2j00\|2j00]], [[2j02\|2j02]], [[2uu9\|2uu9]], [[2uua\|2uua]], [[2uub\|2uub]], [[2uuc\|2uuc]], [[2uxb\|2uxb]], [[2uxc\|2uxc]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v49 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v49 RCSB], [http://www.ebi.ac.uk/pdbsum/2v49 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v49_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In bacteria, disassembly of the ribosome at the end of translation is facilitated by an essential protein factor termed ribosome recycling factor (RRF), which works in concert with elongation factor G. Here we describe the crystal structure of the Thermus thermophilus RRF bound to a 70S ribosomal complex containing a stop codon in the A site, a transfer RNA anticodon stem-loop in the P site and tRNA(fMet) in the E site. The work demonstrates that structures of translation factors bound to 70S ribosomes can be determined at reasonably high resolution. Contrary to earlier reports, we did not observe any RRF-induced changes in bridges connecting the two subunits. This suggests that such changes are not a direct requirement for or consequence of RRF binding but possibly arise from the subsequent stabilization of a hybrid state of the ribosome.

-	~~==About this Structure==~~	+	Crystal structure of the ribosome recycling factor bound to the ribosome.,Weixlbaumer A, Petry S, Dunham CM, Selmer M, Kelley AC, Ramakrishnan V Nat Struct Mol Biol. 2007 Aug;14(8):733-7. Epub 2007 Jul 29. PMID:17660830<ref>PMID:17660830</ref>
-	~~[[2v49]] is a 30 chain~~ structure ~~with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2V49 OCA].~~	+

-	~~==See Also==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	*[[Ribosomal protein L1\|Ribosomal protein L1]]	+	</div>
-	*[[Ribosomal protein L13\|Ribosomal protein L13]]	+
-	*[[Ribosomal protein L14\|Ribosomal protein L14]]	+
-	*[[Ribosomal protein L15\|Ribosomal protein L15]]	+
-	*[[Ribosomal protein L16\|Ribosomal protein L16]]	+
-	*[[Ribosomal protein L17\|Ribosomal protein L17]]	+
-	*[[Ribosomal protein L18\|Ribosomal protein L18]]	+
-	*[[Ribosomal protein L19\|Ribosomal protein L19]]	+
-	*[[Ribosomal protein L2\|Ribosomal protein L2]]	+
-	*[[Ribosomal protein L20\|Ribosomal protein L20]]	+
-	*[[Ribosomal protein L21\|Ribosomal protein L21]]	+
-	*[[Ribosomal protein L22\|Ribosomal protein L22]]	+
-	*[[Ribosomal protein L23\|Ribosomal protein L23]]	+
-	*[[Ribosomal protein L24\|Ribosomal protein L24]]	+
-	*[[Ribosomal protein L25\|Ribosomal protein L25]]	+
-	*[[Ribosomal protein L27\|Ribosomal protein L27]]	+
-	*[[Ribosomal protein L28\|Ribosomal protein L28]]	+
-	*[[Ribosomal protein L29\|Ribosomal protein L29]]	+
-	*[[Ribosomal protein L3\|Ribosomal protein L3]]	+
-	*[[Ribosomal protein L30\|Ribosomal protein L30]]	+
-	*[[Ribosomal protein L31\|Ribosomal protein L31]]	+
-	*[[Ribosomal protein L32\|Ribosomal protein L32]]	+
-	*[[Ribosomal protein L33\|Ribosomal protein L33]]	+
-	*[[Ribosomal protein L34\|Ribosomal protein L34]]	+
-	*[[Ribosomal protein L35\|Ribosomal protein L35]]	+
-	*[[Ribosomal protein L4\|Ribosomal protein L4]]	+
-	*[[Ribosomal protein L5\|Ribosomal protein L5]]	+
-	*[[Ribosomal protein L6\|Ribosomal protein L6]]	+
-	*[[Ribosomal protein L9\|Ribosomal protein L9]]	+
-	*[[Ribosome\|Ribosome]]	+

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:017660830~~</~~ref~~><~~references group="xtra"~~/>	+	*[[Ribosome 3D structures\|Ribosome 3D structures]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Dunham, C M.]]		[[Category: Dunham, C M.]]

OCA at 08:39, 11 March 2013

2013-03-11T08:39:00Z

←Older revision		Revision as of 08:39, 11 March 2013
Line 1:		Line 1:
-	~~[[Image:2v49.png\|left\|200px]]~~	+	{{Large structure}}
-		+
	{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}		{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}
-
	===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===		===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===
-
	{{ABSTRACT_PUBMED_17660830}}		{{ABSTRACT_PUBMED_17660830}}

OCA at 09:00, 20 October 2012

2012-10-20T09:00:02Z

←Older revision		Revision as of 09:00, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2v49]] is a 30 chain structure of [[Ribosomal protein L1]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L15]], [[Ribosomal protein L16]], [[Ribosomal protein L17]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L20]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L27]], [[Ribosomal protein L28]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L31]], [[Ribosomal protein L32]], [[Ribosomal protein L33]], [[Ribosomal protein L34]], [[Ribosomal protein L35]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]], [[Ribosomal protein L9]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].	+	[[2v49]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].

	==See Also==		==See Also==

OCA at 21:28, 25 July 2012

2012-07-25T21:28:56Z

←Older revision		Revision as of 21:28, 25 July 2012
Line 1:		Line 1:
	[[Image:2v49.png\|left\|200px]]		[[Image:2v49.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2v49", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}		{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}

	===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===		===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17660830}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17660830 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17660830}}		{{ABSTRACT_PUBMED_17660830}}

	==About this Structure==		==About this Structure==
-	[[2v49]] is a 30 chain structure of [[Ribosomal protein L1]], [[Ribosomal protein L2]], [[Ribosomal protein L3]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].	+	[[2v49]] is a 30 chain structure of [[Ribosomal protein L1]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L15]], [[Ribosomal protein L16]], [[Ribosomal protein L17]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L20]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L27]], [[Ribosomal protein L28]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L31]], [[Ribosomal protein L32]], [[Ribosomal protein L33]], [[Ribosomal protein L34]], [[Ribosomal protein L35]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]], [[Ribosomal protein L9]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].

	==See Also==		==See Also==
-	*[[Ribosomal protein L1]]	+	*[[Ribosomal protein L1\|Ribosomal protein L1]]
-	*[[Ribosomal protein L2]]	+	*[[Ribosomal protein L13\|Ribosomal protein L13]]
-	*[[Ribosomal protein L3]]	+	*[[Ribosomal protein L14\|Ribosomal protein L14]]
-	*[[Ribosomal protein L4]]	+	*[[Ribosomal protein L15\|Ribosomal protein L15]]
-	*[[Ribosomal protein L5]]	+	*[[Ribosomal protein L16\|Ribosomal protein L16]]
-	*[[Ribosomal protein L6]]	+	*[[Ribosomal protein L17\|Ribosomal protein L17]]
-	*[[Ribosome]]	+	*[[Ribosomal protein L18\|Ribosomal protein L18]]
		+	*[[Ribosomal protein L19\|Ribosomal protein L19]]
		+	*[[Ribosomal protein L2\|Ribosomal protein L2]]
		+	*[[Ribosomal protein L20\|Ribosomal protein L20]]
		+	*[[Ribosomal protein L21\|Ribosomal protein L21]]
		+	*[[Ribosomal protein L22\|Ribosomal protein L22]]
		+	*[[Ribosomal protein L23\|Ribosomal protein L23]]
		+	*[[Ribosomal protein L24\|Ribosomal protein L24]]
		+	*[[Ribosomal protein L25\|Ribosomal protein L25]]
		+	*[[Ribosomal protein L27\|Ribosomal protein L27]]
		+	*[[Ribosomal protein L28\|Ribosomal protein L28]]
		+	*[[Ribosomal protein L29\|Ribosomal protein L29]]
		+	*[[Ribosomal protein L3\|Ribosomal protein L3]]
		+	*[[Ribosomal protein L30\|Ribosomal protein L30]]
		+	*[[Ribosomal protein L31\|Ribosomal protein L31]]
		+	*[[Ribosomal protein L32\|Ribosomal protein L32]]
		+	*[[Ribosomal protein L33\|Ribosomal protein L33]]
		+	*[[Ribosomal protein L34\|Ribosomal protein L34]]
		+	*[[Ribosomal protein L35\|Ribosomal protein L35]]
		+	*[[Ribosomal protein L4\|Ribosomal protein L4]]
		+	*[[Ribosomal protein L5\|Ribosomal protein L5]]
		+	*[[Ribosomal protein L6\|Ribosomal protein L6]]
		+	*[[Ribosomal protein L9\|Ribosomal protein L9]]
		+	*[[Ribosome\|Ribosome]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17660830~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017660830</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Dunham, C M.]]		[[Category: Dunham, C M.]]

OCA: Protected "2v49" [edit=sysop:move=sysop]

2010-12-27T01:58:19Z

Protected "2v49" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:58, 27 December 2010

OCA at 01:58, 27 December 2010

2010-12-27T01:58:17Z

←Older revision		Revision as of 01:58, 27 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2v49.png\|left\|200px]]		[[Image:2v49.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2V49~~ is a ~~31 chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].	+	[[2v49]] is a 30 chain structure of [[Ribosomal protein L1]], [[Ribosomal protein L2]], [[Ribosomal protein L3]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].
		+
		+	==See Also==
		+	*[[Ribosomal protein L1]]
		+	*[[Ribosomal protein L2]]
		+	*[[Ribosomal protein L3]]
		+	*[[Ribosomal protein L4]]
		+	*[[Ribosomal protein L5]]
		+	*[[Ribosomal protein L6]]
		+	*[[Ribosome]]

	==Reference==		==Reference==
Line 37:		Line 45:
	[[Category: Translation]]		[[Category: Translation]]
	[[Category: Trna]]		[[Category: Trna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:59:33 2009''

OCA at 16:59, 16 February 2009

2009-02-16T16:59:34Z

←Older revision		Revision as of 16:59, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2V49 is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].	+	2V49 is a 31 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V49 OCA].

	==Reference==		==Reference==
-	Crystal structure of the ribosome recycling factor bound to the ribosome., Weixlbaumer A, Petry S, Dunham CM, Selmer M, Kelley AC, Ramakrishnan V, Nat Struct Mol Biol. 2007 Aug;14(8):733-7. Epub 2007 Jul 29. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17660830 17660830]~~	+	<ref group="xtra">PMID:17660830</ref><references group="xtra"/>
-	~~[[Category: Protein complex]]~~	+
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Dunham, C M.]]		[[Category: Dunham, C M.]]
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	[[Category: Trna]]		[[Category: Trna]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 23~~:19:~~22 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:59:33 2009''

OCA at 20:19, 27 July 2008

2008-07-27T20:19:31Z

←Older revision		Revision as of 20:19, 27 July 2008
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-	[[Image:2v49.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2v49.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}		{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}

-	~~'''~~STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.~~'''~~	+	===STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.===


-	~~==Overview==~~	+	<!--
-	~~In bacteria~~, ~~disassembly of the ribosome at the end of translation is facilitated by an essential protein factor termed ribosome recycling factor (RRF)~~, ~~which works in concert with elongation factor G. Here we describe the crystal structure of~~ the ~~Thermus thermophilus RRF bound~~ to ~~a 70S ribosomal complex containing a stop codon in~~ the ~~A site, a transfer RNA anticodon stem-loop in the P site and tRNA~~(~~fMet) in the E site. The work demonstrates that structures of translation factors bound to 70S ribosomes can be determined~~ at ~~reasonably high resolution~~. ~~Contrary to earlier reports~~, ~~we did not observe any RRF-induced changes in bridges connecting~~ the ~~two subunits. This suggests that such changes are not a direct requirement for or consequence of RRF binding but possibly arise from the subsequent stabilization of a hybrid state of the ribosome~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_17660830}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 17660830 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_17660830}}

	==About this Structure==		==About this Structure==
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	[[Category: Translation]]		[[Category: Translation]]
	[[Category: Trna]]		[[Category: Trna]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 18~~:11:46 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:19:22 2008''

OCA at 15:11, 4 May 2008

2008-05-04T15:11:48Z

←Older revision		Revision as of 15:11, 4 May 2008
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	[[Image:2v49.gif\|left\|200px]]		[[Image:2v49.gif\|left\|200px]]

-	{{Structure	+	<!--
-	\|PDB~~= 2v49 \|SIZE=350\|CAPTION= <~~scene ~~name='initialview01'>2v49</scene>~~, ~~resolution 3~~.~~50Å~~	+	The line below this paragraph, containing "STRUCTURE_2v49", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=A:ADENOSINE~~-~~5'~~-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene>	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	\|~~ACTIVITY~~=	+	or leave the SCENE parameter empty for the default display.
-	\|~~GENE~~=	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_2v49\| PDB=2v49 \| SCENE= }}
-	\|RELATEDENTRY=[[1fjg\|1FJG]], [[1gix\|1GIX]], [[1i94\|1I94]], [[1i95\|1I95]], [[1i96\|1I96]], [[1i97\|1I97]], [[1ibk\|1IBK]], [[1ibl\|1IBL]], [[1ibm\|1IBM]], [[1j5e\|1J5E]], [[1jgo\|1JGO]], [[1jgp\|1JGP]], [[1jgq\|1JGQ]], [[1l1u\|1L1U]], [[1n32\|1N32]], [[1n33\|1N33]], [[1n34\|1N34]], [[1n36\|1N36]], [[1pns\|1PNS]], [[1pnx\|1PNX]], [[1xmo\|1XMO]], [[1xmq\|1XMQ]], [[1xnq\|1XNQ]], [[1xnr\|1XNR]], [[1yl4\|1YL4]], [[2b64\|2B64]], [[2b9m\|2B9M]], [[2b9o\|2B9O]], [[2f4v\|2F4V]], [[2j00\|2J00]], [[2j02\|2J02]], [[2uu9\|2UU9]], [[2uua\|2UUA]], [[2uub\|2UUB]], [[2uuc\|2UUC]], [[2uxb\|2UXB]], [[2uxc\|2UXC]], [[2v46\|2V46]], [[2v47\|2V47]], [[2v48\|2V48]]	+
-	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v49 OCA], [http://www.ebi.ac.uk/pdbsum/2v49 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2v49 RCSB]</span>	+
-	}}	+

	'''STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.'''		'''STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT OF MOLECULE 2.'''
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	[[Category: Selmer, M.]]		[[Category: Selmer, M.]]
	[[Category: Weixlbaumer, A.]]		[[Category: Weixlbaumer, A.]]
-	[[Category: ~~mrna~~]]	+	[[Category: Mrna]]
-	[[Category: ~~recycling~~]]	+	[[Category: Recycling]]
-	[[Category: ~~ribosome~~]]	+	[[Category: Ribosome]]
-	[[Category: ~~rrf~~]]	+	[[Category: Rrf]]
-	[[Category: ~~translation~~]]	+	[[Category: Translation]]
-	[[Category: ~~trna~~]]	+	[[Category: Trna]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 18:11:46 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 05~~:08:22 2008''	+