2vbt - Revision history

OCA at 15:14, 13 December 2023

2023-12-13T15:14:09Z

←Older revision		Revision as of 15:14, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2vbt' size='340' side='right'caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2vbt' size='340' side='right'caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43067 Atcc 43067~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VBT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VBT FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CDP:CYTIDINE~~-~~5-DIPHOSPHATE'>CDP</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [https://pdbe.org/2vbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [https://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [https://pdbe.org/2vbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [https://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RIFK_METJA RIFK_METJA]] Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).<ref>PMID:18073108</ref> <ref>PMID:18245297</ref>	+	[https://www.uniprot.org/uniprot/RIFK_METJA RIFK_METJA] Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).<ref>PMID:18073108</ref> <ref>PMID:18245297</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43067]]
-	[[Category: CTP-dependent riboflavin kinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ammelburg, M]]	+	[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Djuranovic, S]]	+	[[Category: Ammelburg M]]
-	[[Category: Hartmann~~, M D~~]]	+	[[Category: Djuranovic S]]
-	[[Category: Lupas~~, A N~~]]	+	[[Category: Hartmann MD]]
-	[[Category: Martin, J]]	+	[[Category: Lupas AN]]
-	[[Category: Zeth, K]]	+	[[Category: Martin J]]
-	~~[[Category: Cradle-loop barrel]]~~	+	[[Category: Zeth K]]
-	~~[[Category: Ctp-dependent kinase]]~~	+
-	~~[[Category: Fmn]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 12:43, 23 March 2022

2022-03-23T12:43:46Z

←Older revision		Revision as of 12:43, 23 March 2022
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	<StructureSection load='2vbt' size='340' side='right'caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2vbt' size='340' side='right'caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VBT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VBT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [~~http~~://pdbe.org/2vbt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [https://pdbe.org/2vbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [https://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RIFK_METJA RIFK_METJA]] Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).<ref>PMID:18073108</ref> <ref>PMID:18245297</ref>	+	[[https://www.uniprot.org/uniprot/RIFK_METJA RIFK_METJA]] Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).<ref>PMID:18073108</ref> <ref>PMID:18245297</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:26, 17 June 2020

2020-06-17T11:26:25Z

←Older revision		Revision as of 11:26, 17 June 2020
Line 1:		Line 1:

	==Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4==		==Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4==
-	<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='2vbt' size='340' side='right'caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VBT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VBT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://pdbe.org/2vbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://pdbe.org/2vbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 36:
	[[Category: Atcc 43067]]		[[Category: Atcc 43067]]
	[[Category: CTP-dependent riboflavin kinase]]		[[Category: CTP-dependent riboflavin kinase]]
		+	[[Category: Large Structures]]
	[[Category: Ammelburg, M]]		[[Category: Ammelburg, M]]
	[[Category: Djuranovic, S]]		[[Category: Djuranovic, S]]

OCA at 08:16, 12 September 2018

2018-09-12T08:16:58Z

←Older revision		Revision as of 08:16, 12 September 2018
Line 1:		Line 1:
-	==~~RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH~~ CDP ~~AND~~ PO4==	+
		+	==Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4==
	<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://pdbe.org/2vbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://pdbe.org/2vbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vbt_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vbt_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 12:27, 7 February 2016

2016-02-07T12:27:32Z

←Older revision		Revision as of 12:27, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanocaldococcus_jannaschii Methanocaldococcus jannaschii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VBT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VBT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://pdbe.org/2vbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RIFK_METJA RIFK_METJA]] Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates (PubMed:18245297) or not (PubMed:18073108).<ref>PMID:18073108</ref> <ref>PMID:18245297</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vbt ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2vbt" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 43067]]
	[[Category: CTP-dependent riboflavin kinase]]		[[Category: CTP-dependent riboflavin kinase]]
-	[[Category: Methanocaldococcus jannaschii]]
	[[Category: Ammelburg, M]]		[[Category: Ammelburg, M]]
	[[Category: Djuranovic, S]]		[[Category: Djuranovic, S]]

OCA at 15:01, 19 January 2015

2015-01-19T15:01:48Z

←Older revision		Revision as of 15:01, 19 January 2015
Line 32:		Line 32:
	[[Category: CTP-dependent riboflavin kinase]]		[[Category: CTP-dependent riboflavin kinase]]
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Ammelburg, M.]]	+	[[Category: Ammelburg, M]]
-	[[Category: Djuranovic, S.]]	+	[[Category: Djuranovic, S]]
-	[[Category: Hartmann, M D.]]	+	[[Category: Hartmann, M D]]
-	[[Category: Lupas, A N.]]	+	[[Category: Lupas, A N]]
-	[[Category: Martin, J.]]	+	[[Category: Martin, J]]
-	[[Category: Zeth, K.]]	+	[[Category: Zeth, K]]
	[[Category: Cradle-loop barrel]]		[[Category: Cradle-loop barrel]]
	[[Category: Ctp-dependent kinase]]		[[Category: Ctp-dependent kinase]]
	[[Category: Fmn]]		[[Category: Fmn]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 06:26, 10 October 2014

2014-10-10T06:26:57Z

←Older revision		Revision as of 06:26, 10 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2vbt.~~png~~\|~~left~~\|200px]]	+	==RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND PO4==
		+	<StructureSection load='2vbt' size='340' side='right' caption='[[2vbt]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VBT FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2p3m\|2p3m]], [[2vbs\|2vbs]], [[2vbu\|2vbu]], [[2vbv\|2vbv]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP-dependent_riboflavin_kinase CTP-dependent riboflavin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.161 2.7.1.161] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vbt RCSB], [http://www.ebi.ac.uk/pdbsum/2vbt PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vbt_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Proteins of the cradle-loop barrel metafold are formed by duplication of a conserved betaalphabeta-element, suggesting a common evolutionary origin from an ancestral group of nucleic acid-binding proteins. The basal fold within this metafold, the RIFT barrel, is also found in a wide range of enzymes, whose homologous relationship with the nucleic acid-binding group is unclear. We have characterized a protein family that is intermediate in sequence and structure between the basal group of cradle-loop barrels and one family of RIFT-barrel enzymes, the riboflavin kinases. We report the structure, substrate-binding mode, and catalytic activity for one of these proteins, Methanocaldococcus jannaschii Mj0056, which is an archaeal riboflavin kinase. Mj0056 is unusual in utilizing CTP rather than ATP as the donor nucleotide, and sequence conservation in the relevant residues suggests that this is a general feature of archaeal riboflavin kinases.

-	~~{{STRUCTURE_2vbt\| PDB=2vbt \| SCENE= }}~~	+	A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels.,Ammelburg M, Hartmann MD, Djuranovic S, Alva V, Koretke KK, Martin J, Sauer G, Truffault V, Zeth K, Lupas AN, Coles M Structure. 2007 Dec;15(12):1577-90. PMID:18073108<ref>PMID:18073108</ref>

-	~~===RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND PO4===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18073108}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2vbt]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018073108<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: CTP-dependent riboflavin kinase]]		[[Category: CTP-dependent riboflavin kinase]]
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]

OCA: Protected "2vbt" [edit=sysop:move=sysop]

2013-01-07T21:18:50Z

Protected "2vbt" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:18, 7 January 2013

OCA at 21:18, 7 January 2013

2013-01-07T21:18:47Z

←Older revision		Revision as of 21:18, 7 January 2013
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-	{{Seed}}
	[[Image:2vbt.png\|left\|200px]]		[[Image:2vbt.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2vbt", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2vbt\| PDB=2vbt \| SCENE= }}		{{STRUCTURE_2vbt\| PDB=2vbt \| SCENE= }}

	===RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND PO4===		===RIBOFLAVIN KINASE MJ0056 FROM METHANOCALDOCOCCUS JANNASCHII IN COMPLEX WITH CDP AND PO4===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18073108}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18073108 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18073108}}		{{ABSTRACT_PUBMED_18073108}}

	==About this Structure==		==About this Structure==
-	~~2VBT~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA].	+	[[2vbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18073108~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018073108</ref><references group="xtra"/>
		+	[[Category: CTP-dependent riboflavin kinase]]
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Transferase]]
	[[Category: Ammelburg, M.]]		[[Category: Ammelburg, M.]]
	[[Category: Djuranovic, S.]]		[[Category: Djuranovic, S.]]
Line 36:		Line 24:
	[[Category: Fmn]]		[[Category: Fmn]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:48:14 2009''

OCA at 11:48, 16 February 2009

2009-02-16T11:48:16Z

←Older revision		Revision as of 11:48, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2VBT is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA].	+	2VBT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBT OCA].

	==Reference==		==Reference==
-	A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels., Ammelburg M, Hartmann MD, Djuranovic S, Alva V, Koretke KK, Martin J, Sauer G, Truffault V, Zeth K, Lupas AN, Coles M, Structure. 2007 Dec;15(12):1577-90. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18073108 18073108]~~	+	<ref group="xtra">PMID:18073108</ref><references group="xtra"/>
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Single protein]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Ammelburg, M.]]		[[Category: Ammelburg, M.]]
Line 38:		Line 37:
	[[Category: Transferase]]		[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27~~ 16:19:~~39 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:48:14 2009''