2wic - Revision history

OCA at 10:12, 9 May 2024

2024-05-09T10:12:40Z

←Older revision		Revision as of 10:12, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2wic' size='340' side='right'caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2wic' size='340' side='right'caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus~~ pneumoniae~~" (schroeter 1886) flugge 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WIC FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID~~-~~GUANYLATE+ESTER'>GNP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2wia\|2wia]]~~, ~~[[2wib\|2wib]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [https://pdbe.org/2wic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [https://www.ebi.ac.uk/pdbsum/2wic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [https://pdbe.org/2wic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [https://www.ebi.ac.uk/pdbsum/2wic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A6TF32_KLEP7 A6TF32_KLEP7]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Klebsiella pneumoniae]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chang, Y W]]	+	[[Category: Chang Y-W]]
-	[[Category: Chen, J H]]	+	[[Category: Chen J-H]]
-	[[Category: Chen, Y C]]	+	[[Category: Chen Y-C]]
-	[[Category: Hsiao, C D]]	+	[[Category: Hsiao C-D]]
-	[[Category: Huang, T H]]	+	[[Category: Huang T-H]]
-	[[Category: Hung, K W]]	+	[[Category: Hung K-W]]
-	[[Category: Sun, Y J]]	+	[[Category: Sun Y-J]]
-	~~[[Category: Ferrous iron transport]]~~	+
-	~~[[Category: G protein]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Metal transport]]~~	+
-	~~[[Category: Signal transduction~~]]	+

OCA at 11:08, 6 April 2022

2022-04-06T11:08:22Z

←Older revision		Revision as of 11:08, 6 April 2022
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	<StructureSection load='2wic' size='340' side='right'caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2wic' size='340' side='right'caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WIC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wia\|2wia]], [[2wib\|2wib]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [~~http~~://pdbe.org/2wic PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wic PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [https://pdbe.org/2wic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [https://www.ebi.ac.uk/pdbsum/2wic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:46, 1 July 2020

2020-07-01T08:46:56Z

←Older revision		Revision as of 08:46, 1 July 2020
Line 1:		Line 1:

	==Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella Pneumoniae in GMPPNP binding state==		==Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella Pneumoniae in GMPPNP binding state==
-	<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='2wic' size='340' side='right'caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WIC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [http://pdbe.org/2wic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [http://www.ebi.ac.uk/pdbsum/2wic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [http://pdbe.org/2wic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [http://www.ebi.ac.uk/pdbsum/2wic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chang, Y W]]		[[Category: Chang, Y W]]
	[[Category: Chen, J H]]		[[Category: Chen, J H]]

OCA at 09:50, 26 September 2018

2018-09-26T09:50:14Z

←Older revision		Revision as of 09:50, 26 September 2018
Line 1:		Line 1:

-	==~~CRYSTAL STRUCTURES OF THE~~ N-~~TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN~~ GMPPNP ~~BINDING STATE~~==	+	==Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella Pneumoniae in GMPPNP binding state==
	<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/2wic_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/2wic_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:00, 11 August 2016

2016-08-11T15:00:06Z

←Older revision		Revision as of 15:00, 11 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE==		==CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE==
	<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Klebsiella_pneumoniae Klebsiella~~ pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WIC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [http://www.ebi.ac.uk/pdbsum/2wic PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [http://pdbe.org/2wic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [http://www.ebi.ac.uk/pdbsum/2wic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wic ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wic ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wic" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Klebsiella pneumoniae]]
	[[Category: Chang, Y W]]		[[Category: Chang, Y W]]
	[[Category: Chen, J H]]		[[Category: Chen, J H]]

OCA at 09:30, 25 January 2015

2015-01-25T09:30:40Z

←Older revision		Revision as of 09:30, 25 January 2015
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
-	[[Category: Chang, Y W.]]	+	[[Category: Chang, Y W]]
-	[[Category: Chen, J H.]]	+	[[Category: Chen, J H]]
-	[[Category: Chen, Y C.]]	+	[[Category: Chen, Y C]]
-	[[Category: Hsiao, C D.]]	+	[[Category: Hsiao, C D]]
-	[[Category: Huang, T H.]]	+	[[Category: Huang, T H]]
-	[[Category: Hung, K W.]]	+	[[Category: Hung, K W]]
-	[[Category: Sun, Y J.]]	+	[[Category: Sun, Y J]]
	[[Category: Ferrous iron transport]]		[[Category: Ferrous iron transport]]
	[[Category: G protein]]		[[Category: G protein]]

OCA at 09:33, 5 November 2014

2014-11-05T09:33:07Z

←Older revision		Revision as of 09:33, 5 November 2014
Line 1:		Line 1:
-	[[~~Image:~~2wic.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE==
		+	<StructureSection load='2wic' size='340' side='right' caption='[[2wic]], [[Resolution\|resolution]] 2.05Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WIC FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wia\|2wia]], [[2wib\|2wib]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wic OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wic RCSB], [http://www.ebi.ac.uk/pdbsum/2wic PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/2wic_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	FeoB is a G-protein coupled membrane protein essential for Fe(II) uptake in prokaryotes. Here, we report the crystal structures of the intracellular domain of FeoB (NFeoB) from Klebsiella pneumoniae (KpNFeoB) and Pyrococcus furiosus (PfNFeoB) with and without bound ligands. In the structures, a canonical G-protein domain (G domain) is followed by a helical bundle domain (S-domain), which despite its lack of sequence similarity between species is structurally conserved. In the nucleotide-free state, the G-domain's two switch regions point away from the binding site. This gives rise to an open binding pocket whose shallowness is likely to be responsible for the low nucleotide-binding affinity. Nucleotide binding induced significant conformational changes in the G5 motif which in the case of GMPPNP binding was accompanied by destabilization of the switch I region. In addition to the structural data, we demonstrate that Fe(II)-induced foot printing cleaves the protein close to a putative Fe(II)-binding site at the tip of switch I, and we identify functionally important regions within the S-domain. Moreover, we show that NFeoB exists as a monomer in solution, and that its two constituent domains can undergo large conformational changes. The data show that the S-domain plays important roles in FeoB function.

-	~~{{STRUCTURE_2wic\| PDB=2wic \| SCENE= }}~~	+	Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB.,Hung KW, Chang YW, Eng ET, Chen JH, Chen YC, Sun YJ, Hsiao CD, Dong G, Spasov KA, Unger VM, Huang TH J Struct Biol. 2010 Jun;170(3):501-12. Epub 2010 Feb 1. PMID:20123128<ref>PMID:20123128</ref>

-	~~===CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20123128}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wic]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020123128<~~/~~ref~~><~~ref group="xtra">PMID:015276215</ref><references group="xtra"~~/>	+
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
	[[Category: Chang, Y W.]]		[[Category: Chang, Y W.]]

OCA at 13:23, 30 January 2013

2013-01-30T13:23:38Z

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	[[Image:2wic.png\|left\|200px]]		[[Image:2wic.png\|left\|200px]]

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	{{STRUCTURE_2wic\| PDB=2wic \| SCENE= }}		{{STRUCTURE_2wic\| PDB=2wic \| SCENE= }}

	===CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE===		===CRYSTAL STRUCTURES OF THE N-TERMINAL INTRACELLULAR DOMAIN OF FEOB FROM KLEBSIELLA PNEUMONIAE IN GMPPNP BINDING STATE===

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20123128~~</ref><ref group="xtra">PMID:~~15276215~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020123128</ref><ref group="xtra">PMID:015276215</ref><references group="xtra"/>
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
	[[Category: Chang, Y W.]]		[[Category: Chang, Y W.]]

OCA: Protected "2wic" [edit=sysop:move=sysop]

2011-03-14T19:28:56Z

Protected "2wic" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:28, 14 March 2011

OCA at 19:28, 14 March 2011

2011-03-14T19:28:54Z

←Older revision		Revision as of 19:28, 14 March 2011
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-	~~{{Seed}}~~	+	[[Image:2wic.png\|left\|200px]]
-	[[Image:2wic.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	~~2WIC~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA].	+	[[2wic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIC OCA].

	==Reference==		==Reference==
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	[[Category: Metal transport]]		[[Category: Metal transport]]
	[[Category: Signal transduction]]		[[Category: Signal transduction]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:42:13 2010''